FAQs Sign up for updates

Want to know the latest on AUM's products?

Sign up today to get the most exclusive discounts offers


Guaranteed Knockdown For RNA Silencing and Regulation Studies

Advantages of FANA for RNA Silencing and Regulation Studies

  • Gymnotic (Self) delivery: Uptake of the FANA oligos without a delivery agent. No transfection reagent, formulation, conjugate or viral vector transduction needed for delivery.

  • Excellent uptake of FANAs in primary cells and difficult to transfect cell lines (T- cells, B-cells, neurons, endothelial cells, and others)

  • Ideal for in vivo applications (no formulation, conjugate or viral vector needed for delivery).

  • Ideal for mouse, insect, fish, and amphibian models (no formulation, conjugate or viral vector needed for delivery).

  • Non-toxic toxic and do no cause cell death in cells culture and in vivo, thus eliminating the need to expand the number of cells.

  • Resistant to degradation by serum and cellular nucleases significantly improves duration of activity. FANA oligos do not degrade (up to several weeks/months)

  • Long term sustained silencing (can be used as an alternative to generating stable cell lines)

  • Low non-specific protein binding decreases toxicity.

  • Does not alter the biology of cells and the experimental outcome (as is the case of transfection and delivery reagents)

  • Ability to bind to RNA target with high affinity and specificity.

  • No RISC associated off target effects (as is the case of siRNAs).

  • Effective in low concentrations due high bioavailability.

  • Excellent experimental reproducibility.

  • Saves significant time and resources.

  • Easy to use and Cost effective.

  • Super easy to use (very convenient).

  • Cost efficient.

Order Now