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Pathway Human Homo sapiens

Carboxyterminal post-translational modifications of tubulin

R-HSA-8955332 in Reactome release 97: under Post-translational protein modification, with 46 genes placed in it by the mapping files and 0 child pathways in the hierarchy.

The same number in the other species

Reactome writes the mouse and rat events it infers from a human pathway under the human number with the species token. A door opens only where that species' own list in this release holds the id: R-MMU-8955332 (mouse), R-RNO-8955332 (rat). Whether the event was inferred from this one is what the record says.

01The record

Reactome's own record of this pathway

What this tells you

The pathway list, the hierarchy and the genes on this page are read from the files Reactome publishes for Reactome release 97, built into this site on 2026-09-09: the pathway list, the hierarchy relationship file and the two gene mapping files. The record card is the one live read, Reactome's own record of this pathway.

Reactome's download page describes the mapping files: Mapping files link the source database identifier to the lowest level pathway diagram or subset of the pathway, all levels of the pathway hierarchy or database identifier to all reactions. [R13] The gene list here is the all-levels mapping of NCBI Gene ids, filled from the all-levels mapping of Ensembl ids where the NCBI file has no row for a gene; each row names which file it came from by the shape of its source id. Each row carries the evidence codes the file writes for it, as written and unranked, and both where the file writes both; no page of Reactome's documentation the survey read defines the codes, so this page does not expand them. A gene id the identity files do not name is kept as the source's own id with no door rather than turned into a symbol.

On citing what a search finds, Reactome says: It should be remembered that while we strive to contain the most current and accurate data, Reactome should not be used in citations where other primary sources of information are available. [R12] The record card prints the literature Reactome attaches to a curated pathway for that reason. The data are public domain: All data in the Reactome database and files derived from that data are licensed under the Creative Commons Public Domain Dedication (CC0). User may copy, modify, and distribute these data, even for commercial purposes, without asking for permission. Attribution is encouraged but not required. [R10] The pathway illustrations are licensed apart, under CC BY 4.0, and none is shown here.

A gene on this list is one Reactome places in this pathway in this release, and that is all the row says: it does not say the gene is expressed in a tissue or associated with a disease, which are the other two explorers' questions, read from other sources. Reactome's papers of record are [R01] [R02].

  1. [R01] Ragueneau E, Gong C, Sinquin P, Sevilla C, Beavers D, Grentner A, et al. (2026). The Reactome Knowledgebase 2026. Nucleic Acids Research 54:D673-D681. PMID 41251150, doi 10.1093/nar/gkaf1223.
  2. [R02] Milacic M, Beavers D, Conley P, Gong C, Gillespie M, Griss J, et al. (2024). The Reactome Pathway Knowledgebase 2024. Nucleic Acids Research 52:D672-D678. PMID 37941124, doi 10.1093/nar/gkad1025.
  3. [R10] Reactome, reactome.org. License Agreement. https://reactome.org/license, read 2026-09-09.
  4. [R12] Reactome, reactome.org. Citing us. https://reactome.org/cite, read 2026-09-09.
  5. [R13] Reactome, reactome.org. Download. https://reactome.org/download-data, read 2026-09-09.
Reading this pathway's record from Reactome (the pathway record).Still reading. A first read of a pathway can take a while; this page waits up to 35 seconds for it, and its scripts then bring in the panel, or a line saying what did not arrive.

02The genes

Genes Reactome places in this human pathway

The mapping files place 46 genes in this human pathway; showing 1 to 46, in pages of 100, sorted by symbol for reading. The order carries no ranking.

Genes Reactome places in this human pathway, page 1 of 1
GeneAGBL1AuthorityHGNC:26504Mapping file id123624 NCBI fileEvidenceIEA
GeneAGBL2AuthorityHGNC:26296Mapping file id79841 NCBI fileEvidenceIEA
GeneAGBL3AuthorityHGNC:27981Mapping file id340351 NCBI fileEvidenceIEA
GeneAGBL4AuthorityHGNC:25892Mapping file id84871 NCBI fileEvidenceIEA
GeneAGBL5AuthorityHGNC:26147Mapping file id60509 NCBI fileEvidenceIEA
GeneAGTPBP1AuthorityHGNC:17258Mapping file id23287 NCBI fileEvidenceIEA
GeneLRRC49AuthorityHGNC:25965Mapping file id54839 NCBI fileEvidenceIEA
GeneNICN1AuthorityHGNC:18317Mapping file id84276 NCBI fileEvidenceIEA
GeneSVBPAuthorityHGNC:29204Mapping file id374969 NCBI fileEvidenceIEA
GeneTPGS1AuthorityHGNC:25058Mapping file id91978 NCBI fileEvidenceIEA
GeneTPGS2AuthorityHGNC:24561Mapping file id25941 NCBI fileEvidenceIEA
GeneTTLAuthorityHGNC:21586Mapping file id150465 NCBI fileEvidenceIEA
GeneTTLL1AuthorityHGNC:1312Mapping file id25809 NCBI fileEvidenceIEA
GeneTTLL10AuthorityHGNC:26693Mapping file id254173 NCBI fileEvidenceTAS
GeneTTLL11AuthorityHGNC:18113Mapping file id158135 NCBI fileEvidenceTAS
GeneTTLL12AuthorityHGNC:28974Mapping file id23170 NCBI fileEvidenceTAS
GeneTTLL13AuthorityHGNC:32484Mapping file idENSG00000213471 Ensembl fileEvidenceTAS
GeneTTLL2AuthorityHGNC:21211Mapping file id83887 NCBI fileEvidenceTAS
GeneTTLL3AuthorityHGNC:24483Mapping file id26140 NCBI fileEvidenceTAS
GeneTTLL4AuthorityHGNC:28976Mapping file id9654 NCBI fileEvidenceTAS
GeneTTLL5AuthorityHGNC:19963Mapping file id23093 NCBI fileEvidenceTAS
GeneTTLL6AuthorityHGNC:26664Mapping file id284076 NCBI fileEvidenceTAS
GeneTTLL7AuthorityHGNC:26242Mapping file id79739 NCBI fileEvidenceTAS
GeneTTLL8AuthorityHGNC:34000Mapping file idENSG00000138892 Ensembl fileEvidenceTAS
GeneTTLL9AuthorityHGNC:16118Mapping file id164395 NCBI fileEvidenceTAS
GeneTUBA1AAuthorityHGNC:20766Mapping file id7846 NCBI fileEvidenceIEA, TAS
GeneTUBA1BAuthorityHGNC:18809Mapping file id10376 NCBI fileEvidenceIEA, TAS
GeneTUBA1CAuthorityHGNC:20768Mapping file id84790 NCBI fileEvidenceIEA, TAS
GeneTUBA3CAuthorityHGNC:12408Mapping file id7278 NCBI fileEvidenceIEA, TAS
GeneTUBA3DAuthorityHGNC:24071Mapping file id113457 NCBI fileEvidenceIEA, TAS
GeneTUBA3EAuthorityHGNC:20765Mapping file id112714 NCBI fileEvidenceIEA, TAS
GeneTUBA4AAuthorityHGNC:12407Mapping file id7277 NCBI fileEvidenceIEA, TAS
GeneTUBA4BAuthorityHGNC:18637Mapping file id80086 NCBI fileEvidenceIEA, TAS
GeneTUBA8AuthorityHGNC:12410Mapping file id51807 NCBI fileEvidenceIEA, TAS
GeneTUBAL3AuthorityHGNC:23534Mapping file id79861 NCBI fileEvidenceIEA, TAS
GeneTUBB1AuthorityHGNC:16257Mapping file id81027 NCBI fileEvidenceIEA, TAS
GeneTUBB2AAuthorityHGNC:12412Mapping file id7280 NCBI fileEvidenceIEA, TAS
GeneTUBB2BAuthorityHGNC:30829Mapping file id347733 NCBI fileEvidenceIEA, TAS
GeneTUBB3AuthorityHGNC:20772Mapping file id10381 NCBI fileEvidenceIEA, TAS
GeneTUBB4AAuthorityHGNC:20774Mapping file id10382 NCBI fileEvidenceIEA, TAS
GeneTUBB4BAuthorityHGNC:20771Mapping file id10383 NCBI fileEvidenceIEA, TAS
GeneTUBB6AuthorityHGNC:20776Mapping file id84617 NCBI fileEvidenceIEA, TAS
GeneTUBB8AuthorityHGNC:20773Mapping file id347688 NCBI fileEvidenceIEA, TAS
GeneTUBB8BAuthorityHGNC:24983Mapping file id260334 NCBI fileEvidenceIEA, TAS
GeneVASH1AuthorityHGNC:19964Mapping file id22846 NCBI fileEvidenceIEA
GeneVASH2AuthorityHGNC:25723Mapping file id79805 NCBI fileEvidenceIEA

Evidence codes on this page: IEA, TAS, as the mapping file writes them; a row carrying two was written twice by the file, once under each. The mapping file id says which file placed the gene: an NCBI Gene id from NCBI2Reactome_All_Levels.txt, an Ensembl gene id from Ensembl2Reactome_All_Levels.txt. The two files can disagree about a code, so a row's codes are the one file's view. Measured by this site's build over this release on 2026-09-09: of the 138,908 human pathway-gene pairs both files place, 207 (0.149 per cent, over 47 genes) carry TAS in the Ensembl file where the NCBI rows carry IEA alone.

  • Reactome mapping files, the human rows for this pathway · Reactome release 97 · read · Reactome downloads"NCBI2Reactome_All_Levels.txt" and "Ensembl2Reactome_All_Levels.txt", Reactome, release 97, https://reactome.org/download-data/ (date of access 2026-09-09). Data CC0; attribution encouraged.

03The hierarchy

Parents and children in this release's hierarchy

Children

None: no pathway of this release's list names this one as a parent.

Reactome's hierarchy is a graph rather than a tree: a pathway can sit under more than one parent, and the gene counts are each pathway's own placements at every level under it, so a parent's count is not the sum of its children's.

  • Reactome, the human pathway list and hierarchy relationship file · Reactome release 97 · read · Reactome downloads"ReactomePathways.txt" and "ReactomePathwaysRelation.txt", Reactome, release 97, https://reactome.org/download-data/ (date of access 2026-09-09). Data CC0; attribution encouraged.