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Pathway Human Homo sapiens

Kinesins

R-HSA-983189 in Reactome release 97: under Factors involved in megakaryocyte development and platelet production, with 61 genes placed in it by the mapping files and 0 child pathways in the hierarchy.

The same number in the other species

Reactome writes the mouse and rat events it infers from a human pathway under the human number with the species token. A door opens only where that species' own list in this release holds the id: R-MMU-983189 (mouse), R-RNO-983189 (rat). Whether the event was inferred from this one is what the record says.

01The record

Reactome's own record of this pathway

What this tells you

The pathway list, the hierarchy and the genes on this page are read from the files Reactome publishes for Reactome release 97, built into this site on 2026-09-09: the pathway list, the hierarchy relationship file and the two gene mapping files. The record card is the one live read, Reactome's own record of this pathway.

Reactome's download page describes the mapping files: Mapping files link the source database identifier to the lowest level pathway diagram or subset of the pathway, all levels of the pathway hierarchy or database identifier to all reactions. [R13] The gene list here is the all-levels mapping of NCBI Gene ids, filled from the all-levels mapping of Ensembl ids where the NCBI file has no row for a gene; each row names which file it came from by the shape of its source id. Each row carries the evidence codes the file writes for it, as written and unranked, and both where the file writes both; no page of Reactome's documentation the survey read defines the codes, so this page does not expand them. A gene id the identity files do not name is kept as the source's own id with no door rather than turned into a symbol.

On citing what a search finds, Reactome says: It should be remembered that while we strive to contain the most current and accurate data, Reactome should not be used in citations where other primary sources of information are available. [R12] The record card prints the literature Reactome attaches to a curated pathway for that reason. The data are public domain: All data in the Reactome database and files derived from that data are licensed under the Creative Commons Public Domain Dedication (CC0). User may copy, modify, and distribute these data, even for commercial purposes, without asking for permission. Attribution is encouraged but not required. [R10] The pathway illustrations are licensed apart, under CC BY 4.0, and none is shown here.

A gene on this list is one Reactome places in this pathway in this release, and that is all the row says: it does not say the gene is expressed in a tissue or associated with a disease, which are the other two explorers' questions, read from other sources. Reactome's papers of record are [R01] [R02].

  1. [R01] Ragueneau E, Gong C, Sinquin P, Sevilla C, Beavers D, Grentner A, et al. (2026). The Reactome Knowledgebase 2026. Nucleic Acids Research 54:D673-D681. PMID 41251150, doi 10.1093/nar/gkaf1223.
  2. [R02] Milacic M, Beavers D, Conley P, Gong C, Gillespie M, Griss J, et al. (2024). The Reactome Pathway Knowledgebase 2024. Nucleic Acids Research 52:D672-D678. PMID 37941124, doi 10.1093/nar/gkad1025.
  3. [R10] Reactome, reactome.org. License Agreement. https://reactome.org/license, read 2026-09-09.
  4. [R12] Reactome, reactome.org. Citing us. https://reactome.org/cite, read 2026-09-09.
  5. [R13] Reactome, reactome.org. Download. https://reactome.org/download-data, read 2026-09-09.
Reading this pathway's record from Reactome (the pathway record).Still reading. A first read of a pathway can take a while; this page waits up to 35 seconds for it, and its scripts then bring in the panel, or a line saying what did not arrive.

02The genes

Genes Reactome places in this human pathway

The mapping files place 61 genes in this human pathway; showing 1 to 61, in pages of 100, sorted by symbol for reading. The order carries no ranking.

Genes Reactome places in this human pathway, page 1 of 1
GeneCENPEAuthorityHGNC:1856Mapping file id1062 NCBI fileEvidenceTAS
GeneKIF11AuthorityHGNC:6388Mapping file id3832 NCBI fileEvidenceTAS
GeneKIF12AuthorityHGNC:21495Mapping file id113220 NCBI fileEvidenceTAS
GeneKIF13BAuthorityHGNC:14405Mapping file id23303 NCBI fileEvidenceTAS
GeneKIF15AuthorityHGNC:17273Mapping file id56992 NCBI fileEvidenceIEA, TAS
GeneKIF16BAuthorityHGNC:15869Mapping file id55614 NCBI fileEvidenceTAS
GeneKIF18AAuthorityHGNC:29441Mapping file id81930 NCBI fileEvidenceIEA, TAS
GeneKIF18BAuthorityHGNC:27102Mapping file id146909 NCBI fileEvidenceTAS
GeneKIF19AuthorityHGNC:26735Mapping file id124602 NCBI fileEvidenceTAS
GeneKIF1AAuthorityHGNC:888Mapping file id547 NCBI fileEvidenceTAS
GeneKIF1BAuthorityHGNC:16636Mapping file id23095 NCBI fileEvidenceTAS
GeneKIF1CAuthorityHGNC:6317Mapping file id10749 NCBI fileEvidenceTAS
GeneKIF20AAuthorityHGNC:9787Mapping file id10112 NCBI fileEvidenceTAS
GeneKIF20BAuthorityHGNC:7212Mapping file id9585 NCBI fileEvidenceTAS
GeneKIF21AAuthorityHGNC:19349Mapping file id55605 NCBI fileEvidenceTAS
GeneKIF21BAuthorityHGNC:29442Mapping file id23046 NCBI fileEvidenceTAS
GeneKIF22AuthorityHGNC:6391Mapping file id3835 NCBI fileEvidenceTAS
GeneKIF23AuthorityHGNC:6392Mapping file id9493 NCBI fileEvidenceTAS
GeneKIF25AuthorityHGNC:6390Mapping file id3834 NCBI fileEvidenceTAS
GeneKIF26AAuthorityHGNC:20226Mapping file id26153 NCBI fileEvidenceTAS
GeneKIF26BAuthorityHGNC:25484Mapping file id55083 NCBI fileEvidenceTAS
GeneKIF27AuthorityHGNC:18632Mapping file id55582 NCBI fileEvidenceTAS
GeneKIF2AAuthorityHGNC:6318Mapping file id3796 NCBI fileEvidenceTAS
GeneKIF2BAuthorityHGNC:29443Mapping file id84643 NCBI fileEvidenceTAS
GeneKIF2CAuthorityHGNC:6393Mapping file id11004 NCBI fileEvidenceTAS
GeneKIF3AAuthorityHGNC:6319Mapping file id11127 NCBI fileEvidenceIEA, TAS
GeneKIF3BAuthorityHGNC:6320Mapping file id9371 NCBI fileEvidenceIEA, TAS
GeneKIF3CAuthorityHGNC:6321Mapping file id3797 NCBI fileEvidenceIEA, TAS
GeneKIF4AAuthorityHGNC:13339Mapping file id24137 NCBI fileEvidenceTAS
GeneKIF4BAuthorityHGNC:6322Mapping file id285643 NCBI fileEvidenceTAS
GeneKIF5AAuthorityHGNC:6323Mapping file id3798 NCBI fileEvidenceTAS
GeneKIF5BAuthorityHGNC:6324Mapping file id3799 NCBI fileEvidenceTAS
GeneKIF6AuthorityHGNC:21202Mapping file id221458 NCBI fileEvidenceTAS
GeneKIF9AuthorityHGNC:16666Mapping file id64147 NCBI fileEvidenceIEA, TAS
GeneKIFAP3AuthorityHGNC:17060Mapping file id22920 NCBI fileEvidenceIEA, TAS
GeneKIFC1AuthorityHGNC:6389Mapping file id3833 NCBI fileEvidenceIEA, TAS
GeneKIFC2AuthorityHGNC:29530Mapping file id90990 NCBI fileEvidenceTAS
GeneKLC1AuthorityHGNC:6387Mapping file id3831 NCBI fileEvidenceTAS
GeneKLC2AuthorityHGNC:20716Mapping file id64837 NCBI fileEvidenceTAS
GeneKLC3AuthorityHGNC:20717Mapping file id147700 NCBI fileEvidenceTAS
GeneKLC4AuthorityHGNC:21624Mapping file id89953 NCBI fileEvidenceTAS
GeneRACGAP1AuthorityHGNC:9804Mapping file id29127 NCBI fileEvidenceTAS
GeneTUBA1AAuthorityHGNC:20766Mapping file id7846 NCBI fileEvidenceTAS
GeneTUBA1BAuthorityHGNC:18809Mapping file id10376 NCBI fileEvidenceTAS
GeneTUBA1CAuthorityHGNC:20768Mapping file id84790 NCBI fileEvidenceTAS
GeneTUBA3CAuthorityHGNC:12408Mapping file id7278 NCBI fileEvidenceTAS
GeneTUBA3DAuthorityHGNC:24071Mapping file id113457 NCBI fileEvidenceTAS
GeneTUBA3EAuthorityHGNC:20765Mapping file id112714 NCBI fileEvidenceTAS
GeneTUBA4AAuthorityHGNC:12407Mapping file id7277 NCBI fileEvidenceTAS
GeneTUBA4BAuthorityHGNC:18637Mapping file id80086 NCBI fileEvidenceTAS
GeneTUBA8AuthorityHGNC:12410Mapping file id51807 NCBI fileEvidenceTAS
GeneTUBAL3AuthorityHGNC:23534Mapping file id79861 NCBI fileEvidenceTAS
GeneTUBB1AuthorityHGNC:16257Mapping file id81027 NCBI fileEvidenceTAS
GeneTUBB2AAuthorityHGNC:12412Mapping file id7280 NCBI fileEvidenceTAS
GeneTUBB2BAuthorityHGNC:30829Mapping file id347733 NCBI fileEvidenceTAS
GeneTUBB3AuthorityHGNC:20772Mapping file id10381 NCBI fileEvidenceTAS
GeneTUBB4AAuthorityHGNC:20774Mapping file id10382 NCBI fileEvidenceTAS
GeneTUBB4BAuthorityHGNC:20771Mapping file id10383 NCBI fileEvidenceTAS
GeneTUBB6AuthorityHGNC:20776Mapping file id84617 NCBI fileEvidenceTAS
GeneTUBB8AuthorityHGNC:20773Mapping file id347688 NCBI fileEvidenceTAS
GeneTUBB8BAuthorityHGNC:24983Mapping file id260334 NCBI fileEvidenceTAS

Evidence codes on this page: IEA, TAS, as the mapping file writes them; a row carrying two was written twice by the file, once under each. The mapping file id says which file placed the gene: an NCBI Gene id from NCBI2Reactome_All_Levels.txt, an Ensembl gene id from Ensembl2Reactome_All_Levels.txt. The two files can disagree about a code, so a row's codes are the one file's view. Measured by this site's build over this release on 2026-09-09: of the 138,908 human pathway-gene pairs both files place, 207 (0.149 per cent, over 47 genes) carry TAS in the Ensembl file where the NCBI rows carry IEA alone.

  • Reactome mapping files, the human rows for this pathway · Reactome release 97 · read · Reactome downloads"NCBI2Reactome_All_Levels.txt" and "Ensembl2Reactome_All_Levels.txt", Reactome, release 97, https://reactome.org/download-data/ (date of access 2026-09-09). Data CC0; attribution encouraged.

03The hierarchy

Parents and children in this release's hierarchy

Children

None: no pathway of this release's list names this one as a parent.

Reactome's hierarchy is a graph rather than a tree: a pathway can sit under more than one parent, and the gene counts are each pathway's own placements at every level under it, so a parent's count is not the sum of its children's.

  • Reactome, the human pathway list and hierarchy relationship file · Reactome release 97 · read · Reactome downloads"ReactomePathways.txt" and "ReactomePathwaysRelation.txt", Reactome, release 97, https://reactome.org/download-data/ (date of access 2026-09-09). Data CC0; attribution encouraged.