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Pathway Human Homo sapiens

NuRD complex assembly

R-HSA-9937850 in Reactome release 97: under CHD3, CHD4, CHD5 subfamily, with 96 genes placed in it by the mapping files and 1 child pathway in the hierarchy.

The same number in the other species

Reactome writes the mouse and rat events it infers from a human pathway under the human number with the species token. A door opens only where that species' own list in this release holds the id: R-MMU-9937850 (mouse), R-RNO-9937850 (rat). Whether the event was inferred from this one is what the record says.

01The record

Reactome's own record of this pathway

What this tells you

The pathway list, the hierarchy and the genes on this page are read from the files Reactome publishes for Reactome release 97, built into this site on 2026-09-09: the pathway list, the hierarchy relationship file and the two gene mapping files. The record card is the one live read, Reactome's own record of this pathway.

Reactome's download page describes the mapping files: Mapping files link the source database identifier to the lowest level pathway diagram or subset of the pathway, all levels of the pathway hierarchy or database identifier to all reactions. [R13] The gene list here is the all-levels mapping of NCBI Gene ids, filled from the all-levels mapping of Ensembl ids where the NCBI file has no row for a gene; each row names which file it came from by the shape of its source id. Each row carries the evidence codes the file writes for it, as written and unranked, and both where the file writes both; no page of Reactome's documentation the survey read defines the codes, so this page does not expand them. A gene id the identity files do not name is kept as the source's own id with no door rather than turned into a symbol.

On citing what a search finds, Reactome says: It should be remembered that while we strive to contain the most current and accurate data, Reactome should not be used in citations where other primary sources of information are available. [R12] The record card prints the literature Reactome attaches to a curated pathway for that reason. The data are public domain: All data in the Reactome database and files derived from that data are licensed under the Creative Commons Public Domain Dedication (CC0). User may copy, modify, and distribute these data, even for commercial purposes, without asking for permission. Attribution is encouraged but not required. [R10] The pathway illustrations are licensed apart, under CC BY 4.0, and none is shown here.

A gene on this list is one Reactome places in this pathway in this release, and that is all the row says: it does not say the gene is expressed in a tissue or associated with a disease, which are the other two explorers' questions, read from other sources. Reactome's papers of record are [R01] [R02].

  1. [R01] Ragueneau E, Gong C, Sinquin P, Sevilla C, Beavers D, Grentner A, et al. (2026). The Reactome Knowledgebase 2026. Nucleic Acids Research 54:D673-D681. PMID 41251150, doi 10.1093/nar/gkaf1223.
  2. [R02] Milacic M, Beavers D, Conley P, Gong C, Gillespie M, Griss J, et al. (2024). The Reactome Pathway Knowledgebase 2024. Nucleic Acids Research 52:D672-D678. PMID 37941124, doi 10.1093/nar/gkad1025.
  3. [R10] Reactome, reactome.org. License Agreement. https://reactome.org/license, read 2026-09-09.
  4. [R12] Reactome, reactome.org. Citing us. https://reactome.org/cite, read 2026-09-09.
  5. [R13] Reactome, reactome.org. Download. https://reactome.org/download-data, read 2026-09-09.
Reading this pathway's record from Reactome (the pathway record).Still reading. A first read of a pathway can take a while; this page waits up to 35 seconds for it, and its scripts then bring in the panel, or a line saying what did not arrive.

02The genes

Genes Reactome places in this human pathway

The mapping files place 96 genes in this human pathway; showing 1 to 96, in pages of 100, sorted by symbol for reading. The order carries no ranking.

Genes Reactome places in this human pathway, page 1 of 1
GeneCDK2AP1AuthorityHGNC:14002Mapping file id8099 NCBI fileEvidenceTAS
GeneCDK2AP2AuthorityHGNC:30833Mapping file id10263 NCBI fileEvidenceTAS
GeneCHD3AuthorityHGNC:1918Mapping file id1107 NCBI fileEvidenceTAS
GeneCHD4AuthorityHGNC:1919Mapping file id1108 NCBI fileEvidenceTAS
GeneCHD5AuthorityHGNC:16816Mapping file id26038 NCBI fileEvidenceTAS
GeneFBP1AuthorityHGNC:3606Mapping file id2203 NCBI fileEvidenceTAS
GeneG6PC1AuthorityHGNC:4056Mapping file id2538 NCBI fileEvidenceTAS
GeneGATAD2AAuthorityHGNC:29989Mapping file id54815 NCBI fileEvidenceTAS
GeneGATAD2BAuthorityHGNC:30778Mapping file id57459 NCBI fileEvidenceTAS
GeneH2AB1AuthorityHGNC:22516Mapping file id474382 NCBI fileEvidenceTAS
GeneH2AC14AuthorityHGNC:4727Mapping file id8331 NCBI fileEvidenceTAS
GeneH2AC18AuthorityHGNC:4736Mapping file id8337 NCBI fileEvidenceTAS
GeneH2AC19AuthorityHGNC:29668Mapping file id723790 NCBI fileEvidenceTAS
GeneH2AC20AuthorityHGNC:4738Mapping file id8338 NCBI fileEvidenceTAS
GeneH2AC4AuthorityHGNC:4734Mapping file id8335 NCBI fileEvidenceTAS
GeneH2AC6AuthorityHGNC:4733Mapping file id8334 NCBI fileEvidenceTAS
GeneH2AC7AuthorityHGNC:4729Mapping file id3013 NCBI fileEvidenceTAS
GeneH2AC8AuthorityHGNC:4724Mapping file id3012 NCBI fileEvidenceTAS
GeneH2AJAuthorityHGNC:14456Mapping file id55766 NCBI fileEvidenceTAS
GeneH2AXAuthorityHGNC:4739Mapping file id3014 NCBI fileEvidenceTAS
GeneH2AZ2AuthorityHGNC:20664Mapping file id94239 NCBI fileEvidenceTAS
GeneH2BC1AuthorityHGNC:18730Mapping file id255626 NCBI fileEvidenceTAS
GeneH2BC10AuthorityHGNC:4756Mapping file id8346 NCBI fileEvidenceTAS
GeneH2BC11AuthorityHGNC:4761Mapping file id8970 NCBI fileEvidenceTAS
GeneH2BC12AuthorityHGNC:13954Mapping file id85236 NCBI fileEvidenceTAS
GeneH2BC12LAuthorityHGNC:4762Mapping file id54145 NCBI fileEvidenceTAS
GeneH2BC13AuthorityHGNC:4748Mapping file id8340 NCBI fileEvidenceTAS
GeneH2BC14AuthorityHGNC:4750Mapping file id8342 NCBI fileEvidenceTAS
GeneH2BC15AuthorityHGNC:4749Mapping file id8341 NCBI fileEvidenceTAS
GeneH2BC17AuthorityHGNC:4758Mapping file id8348 NCBI fileEvidenceTAS
GeneH2BC21AuthorityHGNC:4760Mapping file id8349 NCBI fileEvidenceTAS
GeneH2BC26AuthorityHGNC:20514Mapping file id128312 NCBI fileEvidenceTAS
GeneH2BC3AuthorityHGNC:4751Mapping file id3018 NCBI fileEvidenceTAS
GeneH2BC4AuthorityHGNC:4757Mapping file id8347 NCBI fileEvidenceTAS
GeneH2BC5AuthorityHGNC:4747Mapping file id3017 NCBI fileEvidenceTAS
GeneH2BC6AuthorityHGNC:4753Mapping file id8344 NCBI fileEvidenceTAS
GeneH2BC7AuthorityHGNC:4752Mapping file id8343 NCBI fileEvidenceTAS
GeneH2BC8AuthorityHGNC:4746Mapping file id8339 NCBI fileEvidenceTAS
GeneH2BC9AuthorityHGNC:4755Mapping file id8345 NCBI fileEvidenceTAS
GeneH3-3AAuthorityHGNC:4764Mapping file id3020 NCBI fileEvidenceTAS
GeneH3-3BAuthorityHGNC:4765Mapping file id3021 NCBI fileEvidenceTAS
GeneH3C1AuthorityHGNC:4766Mapping file id8350 NCBI fileEvidenceTAS
GeneH3C10AuthorityHGNC:4775Mapping file id8357 NCBI fileEvidenceTAS
GeneH3C11AuthorityHGNC:4771Mapping file id8354 NCBI fileEvidenceTAS
GeneH3C12AuthorityHGNC:4774Mapping file id8356 NCBI fileEvidenceTAS
GeneH3C13AuthorityHGNC:25311Mapping file id653604 NCBI fileEvidenceTAS
GeneH3C14AuthorityHGNC:20503Mapping file id126961 NCBI fileEvidenceTAS
GeneH3C15AuthorityHGNC:20505Mapping file id333932 NCBI fileEvidenceTAS
GeneH3C2AuthorityHGNC:4776Mapping file id8358 NCBI fileEvidenceTAS
GeneH3C3AuthorityHGNC:4768Mapping file id8352 NCBI fileEvidenceTAS
GeneH3C4AuthorityHGNC:4767Mapping file id8351 NCBI fileEvidenceTAS
GeneH3C6AuthorityHGNC:4769Mapping file id8353 NCBI fileEvidenceTAS
GeneH3C7AuthorityHGNC:4773Mapping file id8968 NCBI fileEvidenceTAS
GeneH3C8AuthorityHGNC:4772Mapping file id8355 NCBI fileEvidenceTAS
GeneH4C1AuthorityHGNC:4781Mapping file id8359 NCBI fileEvidenceTAS
GeneH4C11AuthorityHGNC:4785Mapping file id8363 NCBI fileEvidenceTAS
GeneH4C12AuthorityHGNC:4784Mapping file id8362 NCBI fileEvidenceTAS
GeneH4C13AuthorityHGNC:4791Mapping file id8368 NCBI fileEvidenceTAS
GeneH4C14AuthorityHGNC:4794Mapping file id8370 NCBI fileEvidenceTAS
GeneH4C15AuthorityHGNC:29607Mapping file id554313 NCBI fileEvidenceTAS
GeneH4C16AuthorityHGNC:20510Mapping file id121504 NCBI fileEvidenceTAS
GeneH4C2AuthorityHGNC:4789Mapping file id8366 NCBI fileEvidenceTAS
GeneH4C3AuthorityHGNC:4787Mapping file id8364 NCBI fileEvidenceTAS
GeneH4C4AuthorityHGNC:4782Mapping file id8360 NCBI fileEvidenceTAS
GeneH4C5AuthorityHGNC:4790Mapping file id8367 NCBI fileEvidenceTAS
GeneH4C6AuthorityHGNC:4783Mapping file id8361 NCBI fileEvidenceTAS
GeneH4C8AuthorityHGNC:4788Mapping file id8365 NCBI fileEvidenceTAS
GeneH4C9AuthorityHGNC:4793Mapping file id8294 NCBI fileEvidenceTAS
GeneHDAC1AuthorityHGNC:4852Mapping file id3065 NCBI fileEvidenceTAS
GeneHDAC2AuthorityHGNC:4853Mapping file id3066 NCBI fileEvidenceTAS
GeneIKZF1AuthorityHGNC:13176Mapping file id10320 NCBI fileEvidenceTAS
GeneIKZF2AuthorityHGNC:13177Mapping file id22807 NCBI fileEvidenceTAS
GeneIKZF3AuthorityHGNC:13178Mapping file id22806 NCBI fileEvidenceTAS
GeneMBD2AuthorityHGNC:6917Mapping file id8932 NCBI fileEvidenceTAS
GeneMBD3AuthorityHGNC:6918Mapping file id53615 NCBI fileEvidenceTAS
GeneMBD3L1AuthorityHGNC:15774Mapping file id85509 NCBI fileEvidenceTAS
GeneMBD3L2AuthorityHGNC:18532Mapping file id125997 NCBI fileEvidenceTAS
GeneMTA1AuthorityHGNC:7410Mapping file id9112 NCBI fileEvidenceTAS
GeneMTA2AuthorityHGNC:7411Mapping file id9219 NCBI fileEvidenceTAS
GeneMTA3AuthorityHGNC:23784Mapping file id57504 NCBI fileEvidenceTAS
GeneNR2C2AuthorityHGNC:7972Mapping file id7182 NCBI fileEvidenceTAS
GeneNR2F2AuthorityHGNC:7976Mapping file id7026 NCBI fileEvidenceTAS
GenePCK1AuthorityHGNC:8724Mapping file id5105 NCBI fileEvidenceTAS
GenePHF6AuthorityHGNC:18145Mapping file id84295 NCBI fileEvidenceTAS
GenePWWP2AAuthorityHGNC:29406Mapping file id114825 NCBI fileEvidenceTAS
GenePWWP2BAuthorityHGNC:25150Mapping file id170394 NCBI fileEvidenceTAS
GeneRBBP4AuthorityHGNC:9887Mapping file id5928 NCBI fileEvidenceTAS
GeneRBBP7AuthorityHGNC:9890Mapping file id5931 NCBI fileEvidenceTAS
GeneSUMO1AuthorityHGNC:12502Mapping file id7341 NCBI fileEvidenceTAS
GeneTCF19AuthorityHGNC:11629Mapping file id6941 NCBI fileEvidenceTAS
GeneUBE2IAuthorityHGNC:12485Mapping file id7329 NCBI fileEvidenceTAS
GeneZMYND8AuthorityHGNC:9397Mapping file id23613 NCBI fileEvidenceTAS
GeneZNF532AuthorityHGNC:30940Mapping file id55205 NCBI fileEvidenceTAS
GeneZNF592AuthorityHGNC:28986Mapping file id9640 NCBI fileEvidenceTAS
GeneZNF687AuthorityHGNC:29277Mapping file id57592 NCBI fileEvidenceTAS
GeneZNF827AuthorityHGNC:27193Mapping file id152485 NCBI fileEvidenceTAS

Evidence codes on this page: TAS, as the mapping file writes them; a row carrying two was written twice by the file, once under each. The mapping file id says which file placed the gene: an NCBI Gene id from NCBI2Reactome_All_Levels.txt, an Ensembl gene id from Ensembl2Reactome_All_Levels.txt. The two files can disagree about a code, so a row's codes are the one file's view. Measured by this site's build over this release on 2026-09-09: of the 138,908 human pathway-gene pairs both files place, 207 (0.149 per cent, over 47 genes) carry TAS in the Ensembl file where the NCBI rows carry IEA alone.

  • Reactome mapping files, the human rows for this pathway · Reactome release 97 · read · Reactome downloads"NCBI2Reactome_All_Levels.txt" and "Ensembl2Reactome_All_Levels.txt", Reactome, release 97, https://reactome.org/download-data/ (date of access 2026-09-09). Data CC0; attribution encouraged.

03The hierarchy

Parents and children in this release's hierarchy

Reactome's hierarchy is a graph rather than a tree: a pathway can sit under more than one parent, and the gene counts are each pathway's own placements at every level under it, so a parent's count is not the sum of its children's.

  • Reactome, the human pathway list and hierarchy relationship file · Reactome release 97 · read · Reactome downloads"ReactomePathways.txt" and "ReactomePathwaysRelation.txt", Reactome, release 97, https://reactome.org/download-data/ (date of access 2026-09-09). Data CC0; attribution encouraged.