Gene Human Homo sapiens

CMIP

c-Maf inducing protein

gene with protein product

Human CMIPMouseRat

Reading the ortholog votes for mouse and rat.

Location: Cytogenetic band 16q23.2-q23.3NCBI: 16:81,444,808-81,711,762 on the plus strand, GRCh38.p14 (GCF_000001405.40), sequence NC_000016.10, annotation GCF_000001405.40-RS_2025_08 of 2025-08-01Ensembl: no location was read.Coordinates are one-based with both ends included, as each source reports them.

Gene identity, from HGNC · HGNC 2026-09-29 · read 2026-09-30 ET · HGNC:24319

Notes from the sources

Ensembl did not answer (upstream error).
Ensembl did not answer (upstream error); the Ensembl location and release are missing

Silence this gene

The order page opens with CMIP and human filled in. The sequences are designed against the transcripts below; the price is on that page.

Order for CMIP

sdASO, toASO or siRNA, chosen on the next page

Bring your own sequence Transcripts

For research use only. Not for use in diagnostic or therapeutic procedures.

Summary
Transcripts
Expression
Protein
Interactions
Pathways
Disease
Variants
Constraint
Orthologs
MicroRNAs
Long non-coding RNAs
Literature
Silencing this gene

A line below that says it is reading needs JavaScript to be replaced: with scripts off, it stays at that line however long you wait. Opening a card also needs JavaScript.

Ready in a moment

01 Summary and function

What CMIP does

This gene encodes a c-Maf inducing protein that plays a role in T-cell…

NCBI Gene summary

Ready in a moment

02 Transcripts and isoforms

The RNA a design targets

11 RefSeq transcripts on GRCh38.p14; MANE Select NM_198390.3. Ensembl is not answering, so the Ensembl transcripts could not be shown. Try again later. Reference 44d91765-8f3.

NCBI Datasets

Ready in a moment

03 Expression by tissue

Where CMIP is expressed

Reading GTEx and the Human Protein Atlas.Still reading. A first read of a gene can take a while; this page waits up to 80 seconds for it, and its scripts then bring in this line, or a line saying what did not arrive.

Ready in a moment

04 Protein

The protein CMIP encodes

Reading UniProt, InterPro, AlphaFold DB and PDBe.Still reading. A first read of a gene can take a while; this page waits up to 80 seconds for it, and its scripts then bring in this line, or a line saying what did not arrive.

Ready in a moment

05 Interactions

Proteins STRING associates with CMIP

Reading STRING.Still reading. A first read of a gene can take a while; this page waits up to 50 seconds for it, and its scripts then bring in this line, or a line saying what did not arrive.

Ready in a moment

06 Pathways

Where CMIP acts, as Reactome curates it

Reading UniProt and Reactome.Still reading. A first read of a gene can take a while; this page waits up to 60 seconds for it, and its scripts then bring in this line, or a line saying what did not arrive.

Ready in a moment

07 Disease associations

Diseases linked to CMIP

Reading Open Targets and ClinGen.Still reading. A first read of a gene can take a while; this page waits up to 105 seconds for it, and its scripts then bring in this line, or a line saying what did not arrive.

Ready in a moment

08 Variants

Classified variants of CMIP

Reading ClinVar.Still reading. A first read of a gene can take a while; this page waits up to 60 seconds for it, and its scripts then bring in this line, or a line saying what did not arrive.

Ready in a moment

09 Constraint

How much variation CMIP tolerates

Reading gnomAD and Open Targets.Still reading. A first read of a gene can take a while; this page waits up to 45 seconds for it, and its scripts then bring in this line, or a line saying what did not arrive.

Ready in a moment

10 Orthologs

The same gene in mouse, rat and human

Reading the Alliance, NCBI, Ensembl Compara and RGD.Still reading. A first read of a gene can take a while; this page waits up to 145 seconds for it, and its scripts then bring in this line, or a line saying what did not arrive.

Ready in a moment

11 MicroRNAs

MicroRNAs hosted within CMIP

Ensembl is not answering, so the non-coding annotation could not be shown. Try again later. Reference b27e8932-ed5.

Ready in a moment

12 Long non-coding RNAs

Long non-coding RNAs at the CMIP locus

Ensembl is not answering, so the non-coding annotation could not be shown. Try again later. Reference b27e8932-ed5.

Ready in a moment

13 Literature

Papers that mention CMIP

Reading Europe PMC.Still reading. A first read of a gene can take a while; this page waits up to 55 seconds for it, and its scripts then bring in this line, or a line saying what did not arrive.

Ready in a moment

14 Silencing this gene

From CMIP to a sequence that silences it

The AUMsilence platform designs the sequences against the human transcripts on this page. Six decisions are yours before it does. What is written under each is AUM's guidance; the timings and the concentrations are in the usage guide below.

01
Choose the region
A knockdown oligonucleotide can sit in the 5' untranslated region, the coding sequence or the 3' untranslated region, and all three are used. The coding sequence and the 3' untranslated region are the usual first choices for an RNase H design; the 5' end near the start codon suits a steric block. The map above shows where each region sits on the isoforms it draws.
02
Cover the isoforms you mean
An exon every isoform carries silences the whole gene; an exon only some isoforms carry silences those and spares the rest. Decide which you want before a sequence is chosen, and check the reference transcript (MANE Select in human; RefSeq Select and Ensembl canonical in mouse and rat) is the one your cells express.
03
Think across species early
The orthologs panel says whether mouse and rat carry the same gene. Whether one oligonucleotide can serve two species is a sequence question, settled at design by matching the candidate against each transcript, not by the protein identity shown there.
04
Check expression in your model
A transcript that is not expressed in your cells cannot show knockdown. Confirm the gene is expressed in the cell type and condition you will use, from your own data or a reference atlas, before the order. The expression panel above gives GTEx's median per tissue for a human gene; for mouse and rat it says that no atlas is on this page yet.
05
Run the controls
A scramble control of the same chemistry, a positive control against a gene known to knock down in your cells, untreated cells, and a mock condition where a transfection reagent is used. Read knockdown at the RNA level first, then at the protein; the usage guide gives the timing and the concentrations to start from.
06
Pick the product
AUMsilence sdASO needs no transfection reagent and works in the cells that resist one. AUMsilence toASO is the transfection-optimised version of the same design, and AUMsiRNA is the siRNA route. The selection guide compares them.

Order for CMIP Bring your own sequence The usage guide Selection guide

For research use only. Not for use in diagnostic or therapeutic procedures.

Gene Human Homo sapiens

CMIP

Reading the record for CMIP from HGNC, NCBI Gene and Ensembl.Still reading. A first read of a gene can take a while; this page waits up to 115 seconds for it, and its scripts then bring in the page, or a line saying what did not arrive.

The full name, the identifiers, the location and the notes from the sources arrive with the record. Nothing is filled in ahead of it.

Order door

The door to order for CMIP opens with the record, which decides which product it carries. The order page itself is open now.

Bring your own sequence

For research use only. Not for use in diagnostic or therapeutic procedures.

This page is still reading the record. Its scripts replace this shell with the record when it arrives; with scripts off, it stays at this shell however long you wait.

01 Summary and function

What CMIP does

Waiting for the record before reading NCBI Gene and UniProt.

02 Transcripts and isoforms

The RNA a design targets

Waiting for the record before reading NCBI Datasets and Ensembl.

03 Expression by tissue

Where CMIP is expressed

Waiting for the record before reading GTEx and the Human Protein Atlas.

04 Protein

The protein CMIP encodes

Waiting for the record before reading UniProt, InterPro, AlphaFold DB and PDBe.

05 Interactions

Proteins STRING associates with CMIP

Waiting for the record before reading STRING.

06 Pathways

Where CMIP acts, as Reactome curates it

Waiting for the record before reading UniProt and Reactome.

07 Disease associations

Diseases linked to CMIP

Waiting for the record before reading Open Targets and ClinGen.

08 Variants

Classified variants of CMIP

Waiting for the record before reading ClinVar.

09 Constraint

How much variation CMIP tolerates

Waiting for the record before reading gnomAD and Open Targets.

10 Orthologs

The same gene in mouse, rat and human

Waiting for the record before reading the Alliance, NCBI, Ensembl Compara and RGD.

11 MicroRNAs

MicroRNAs hosted within CMIP

Waiting for the record before reading Ensembl and miRBase.

12 Long non-coding RNAs

Long non-coding RNAs at the CMIP locus

Waiting for the record before reading Ensembl.

13 Literature

Papers that mention CMIP

Waiting for the record before reading Europe PMC.

Accession	Name	Biotype	Labels	Exons	Spliced length	Protein	Sequence
NM_198390.3matches ENST00000537098.8	transcript variant 1	protein coding	MANE Select	21	4,719 nt	773 aaNP_938204.2	Ready in a moment
XM_047434717.1	transcript variant X1	protein coding model	none	22	21,470 nt	757 aaXP_047290673.1	Ready in a moment
XM_011523352.2	transcript variant X2	protein coding model	none	20	4,671 nt	757 aaXP_011521654.1	Ready in a moment
NM_030629.3matches ENST00000539778.7	transcript variant 2	protein coding	none	21	4,126 nt	679 aaNP_085132.1	Ready in a moment
XM_005256179.6	transcript variant X3	protein coding model	none	21	4,104 nt	701 aaXP_005256236.5	Ready in a moment
XM_047434721.1	transcript variant X9	protein coding model	none	19	4,104 nt	586 aaXP_047290677.1	Ready in a moment
XM_005256181.3matches ENST00000566513.6	transcript variant X7	protein coding model	none	20	4,099 nt	586 aaXP_005256238.1	Ready in a moment
XM_047434719.1matches ENST00000398040.9	transcript variant X4	protein coding model	none	19	4,049 nt	631 aaXP_047290675.1	Ready in a moment
XM_047434720.1	transcript variant X8	protein coding model	none	20	3,968 nt	586 aaXP_047290676.1	Ready in a moment
XM_017023733.2	transcript variant X6	protein coding model	none	19	3,883 nt	586 aaXP_016879222.1	Ready in a moment
XM_005256182.1	transcript variant X5	protein coding model	none	19	3,845 nt	586 aaXP_005256239.1	Ready in a moment

Accession	Name	Biotype	Labels	Exons	Spliced length	Protein	Sequence
NM_198390.3matches ENST00000537098.8	transcript variant 1	protein coding	MANE Select	21	4,719 nt	773 aaNP_938204.2	Ready in a moment
XM_047434717.1	transcript variant X1	protein coding model	none	22	21,470 nt	757 aaXP_047290673.1	Ready in a moment
XM_011523352.2	transcript variant X2	protein coding model	none	20	4,671 nt	757 aaXP_011521654.1	Ready in a moment
NM_030629.3matches ENST00000539778.7	transcript variant 2	protein coding	none	21	4,126 nt	679 aaNP_085132.1	Ready in a moment
XM_005256179.6	transcript variant X3	protein coding model	none	21	4,104 nt	701 aaXP_005256236.5	Ready in a moment
XM_047434721.1	transcript variant X9	protein coding model	none	19	4,104 nt	586 aaXP_047290677.1	Ready in a moment
XM_005256181.3matches ENST00000566513.6	transcript variant X7	protein coding model	none	20	4,099 nt	586 aaXP_005256238.1	Ready in a moment
XM_047434719.1matches ENST00000398040.9	transcript variant X4	protein coding model	none	19	4,049 nt	631 aaXP_047290675.1	Ready in a moment
XM_047434720.1	transcript variant X8	protein coding model	none	20	3,968 nt	586 aaXP_047290676.1	Ready in a moment
XM_017023733.2	transcript variant X6	protein coding model	none	19	3,883 nt	586 aaXP_016879222.1	Ready in a moment
XM_005256182.1	transcript variant X5	protein coding model	none	19	3,845 nt	586 aaXP_005256239.1	Ready in a moment

CMIP

What CMIP does

The RNA a design targets

Where CMIP is expressed

The protein CMIP encodes

Proteins STRING associates with CMIP

Where CMIP acts, as Reactome curates it

Diseases linked to CMIP

Classified variants of CMIP

How much variation CMIP tolerates

The same gene in mouse, rat and human

MicroRNAs hosted within CMIP

Long non-coding RNAs at the CMIP locus

Papers that mention CMIP

From CMIP to a sequence that silences it

Choose the region

Cover the isoforms you mean

Think across species early

Check expression in your model

Run the controls

Pick the product

CMIP

What CMIP does

The RNA a design targets

Where CMIP is expressed

The protein CMIP encodes

Proteins STRING associates with CMIP

Where CMIP acts, as Reactome curates it

Diseases linked to CMIP

Classified variants of CMIP

How much variation CMIP tolerates

The same gene in mouse, rat and human

MicroRNAs hosted within CMIP

Long non-coding RNAs at the CMIP locus

Papers that mention CMIP

CMIP

What CMIP does

Gene summary

Protein function

The RNA a design targets

RefSeq 11 transcripts

A window on one transcript

Ensembl 0 transcripts

Where CMIP is expressed

The protein CMIP encodes

Proteins STRING associates with CMIP

Where CMIP acts, as Reactome curates it

Diseases linked to CMIP

Classified variants of CMIP

How much variation CMIP tolerates

The same gene in mouse, rat and human

MicroRNAs hosted within CMIP

Long non-coding RNAs at the CMIP locus

Papers that mention CMIP

From CMIP to a sequence that silences it

Choose the region

Cover the isoforms you mean

Think across species early

Check expression in your model

Run the controls

Pick the product

Gene summary

Protein function

RefSeq 11 transcripts

A window on one transcript

Ensembl 0 transcripts