Gene Human Homo sapiens

ELOVL7

ELOVL fatty acid elongase 7

gene with protein product

Human ELOVL7MouseRat

Reading the ortholog votes for mouse and rat.

Location: Cytogenetic band 5q12.1NCBI: 5:60,751,791-60,844,269 on the minus strand, GRCh38.p14 (GCF_000001405.40), sequence NC_000005.10, annotation GCF_000001405.40-RS_2025_08 of 2025-08-01Ensembl: 5:60,751,791-60,844,589 on the minus strand, GRCh38.p14 (GCA_000001405.29), release 116Coordinates are one-based with both ends included, as each source reports them.
Also known as: FLJ23563

Gene identity, from HGNC · HGNC 2026-09-18 · read 2026-09-23 ET · HGNC:26292

Silence this gene

The order page opens with ELOVL7 and human filled in. The sequences are designed against the transcripts below; the price is on that page.

Order for ELOVL7

sdASO, toASO or siRNA, chosen on the next page

Bring your own sequence Transcripts

For research use only. Not for use in diagnostic or therapeutic procedures.

Summary
Transcripts
Expression
Protein
Interactions
Pathways
Disease
Variants
Constraint
Orthologs
MicroRNAs
Long non-coding RNAs
Literature
Silencing this gene

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Ready in a moment

01 Summary and function

What ELOVL7 does

Enables fatty acid elongase activity.

NCBI Gene summary

Ready in a moment

02 Transcripts and isoforms

The RNA a design targets

Reading NCBI Datasets and Ensembl.Still reading. A first read of a gene can take a while; this page waits up to 80 seconds for it, and its scripts then bring in this line, or a line saying what did not arrive.

Ready in a moment

03 Expression by tissue

Where ELOVL7 is expressed

Reading GTEx and the Human Protein Atlas.Still reading. A first read of a gene can take a while; this page waits up to 80 seconds for it, and its scripts then bring in this line, or a line saying what did not arrive.

Ready in a moment

04 Protein

The protein ELOVL7 encodes

Reading UniProt, InterPro, AlphaFold DB and PDBe.Still reading. A first read of a gene can take a while; this page waits up to 80 seconds for it, and its scripts then bring in this line, or a line saying what did not arrive.

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05 Interactions

Proteins STRING associates with ELOVL7

Reading STRING.Still reading. A first read of a gene can take a while; this page waits up to 50 seconds for it, and its scripts then bring in this line, or a line saying what did not arrive.

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06 Pathways

Where ELOVL7 acts, as Reactome curates it

Reading UniProt and Reactome.Still reading. A first read of a gene can take a while; this page waits up to 60 seconds for it, and its scripts then bring in this line, or a line saying what did not arrive.

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07 Disease associations

Diseases linked to ELOVL7

Reading Open Targets and ClinGen.Still reading. A first read of a gene can take a while; this page waits up to 105 seconds for it, and its scripts then bring in this line, or a line saying what did not arrive.

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08 Variants

Classified variants of ELOVL7

Reading ClinVar.Still reading. A first read of a gene can take a while; this page waits up to 60 seconds for it, and its scripts then bring in this line, or a line saying what did not arrive.

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09 Constraint

How much variation ELOVL7 tolerates

Reading gnomAD and Open Targets.Still reading. A first read of a gene can take a while; this page waits up to 45 seconds for it, and its scripts then bring in this line, or a line saying what did not arrive.

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10 Orthologs

The same gene in mouse, rat and human

Reading the Alliance, NCBI, Ensembl Compara and RGD.Still reading. A first read of a gene can take a while; this page waits up to 145 seconds for it, and its scripts then bring in this line, or a line saying what did not arrive.

Ready in a moment

11 MicroRNAs

MicroRNAs hosted within ELOVL7

Reading Ensembl and miRBase.Still reading. A first read of a gene can take a while; this page waits up to 110 seconds for it, and its scripts then bring in this line, or a line saying what did not arrive.

Ready in a moment

12 Long non-coding RNAs

Long non-coding RNAs at the ELOVL7 locus

Reading Ensembl.Still reading. A first read of a gene can take a while; this page waits up to 110 seconds for it, and its scripts then bring in this line, or a line saying what did not arrive.

Ready in a moment

13 Literature

Papers that mention ELOVL7

Europe PMC is not answering, so the literature search could not be shown. Try again later. Reference 412bc2b5-8c7.

Ready in a moment

14 Silencing this gene

From ELOVL7 to a sequence that silences it

The AUMsilence platform designs the sequences against the human transcripts on this page. Six decisions are yours before it does. What is written under each is AUM's guidance; the timings and the concentrations are in the usage guide below.

01
Choose the region
A knockdown oligonucleotide can sit in the 5' untranslated region, the coding sequence or the 3' untranslated region, and all three are used. The coding sequence and the 3' untranslated region are the usual first choices for an RNase H design; the 5' end near the start codon suits a steric block. The map above shows where each region sits on the isoforms it draws.
02
Cover the isoforms you mean
An exon every isoform carries silences the whole gene; an exon only some isoforms carry silences those and spares the rest. Decide which you want before a sequence is chosen, and check the reference transcript (MANE Select in human; RefSeq Select and Ensembl canonical in mouse and rat) is the one your cells express.
03
Think across species early
The orthologs panel says whether mouse and rat carry the same gene. Whether one oligonucleotide can serve two species is a sequence question, settled at design by matching the candidate against each transcript, not by the protein identity shown there.
04
Check expression in your model
A transcript that is not expressed in your cells cannot show knockdown. Confirm the gene is expressed in the cell type and condition you will use, from your own data or a reference atlas, before the order. The expression panel above gives GTEx's median per tissue for a human gene; for mouse and rat it says that no atlas is on this page yet.
05
Run the controls
A scramble control of the same chemistry, a positive control against a gene known to knock down in your cells, untreated cells, and a mock condition where a transfection reagent is used. Read knockdown at the RNA level first, then at the protein; the usage guide gives the timing and the concentrations to start from.
06
Pick the product
AUMsilence sdASO needs no transfection reagent and works in the cells that resist one. AUMsilence toASO is the transfection-optimised version of the same design, and AUMsiRNA is the siRNA route. The selection guide compares them.

Order for ELOVL7 Bring your own sequence The usage guide Selection guide

For research use only. Not for use in diagnostic or therapeutic procedures.

Gene Human Homo sapiens

ELOVL7

Reading the record for ELOVL7 from HGNC, NCBI Gene and Ensembl.Still reading. A first read of a gene can take a while; this page waits up to 115 seconds for it, and its scripts then bring in the page, or a line saying what did not arrive.

The full name, the identifiers, the location and the notes from the sources arrive with the record. Nothing is filled in ahead of it.

Order door

The door to order for ELOVL7 opens with the record, which decides which product it carries. The order page itself is open now.

Bring your own sequence

For research use only. Not for use in diagnostic or therapeutic procedures.

This page is still reading the record. Its scripts replace this shell with the record when it arrives; with scripts off, it stays at this shell however long you wait.

01 Summary and function

What ELOVL7 does

Waiting for the record before reading NCBI Gene and UniProt.

02 Transcripts and isoforms

The RNA a design targets

Waiting for the record before reading NCBI Datasets and Ensembl.

03 Expression by tissue

Where ELOVL7 is expressed

Waiting for the record before reading GTEx and the Human Protein Atlas.

04 Protein

The protein ELOVL7 encodes

Waiting for the record before reading UniProt, InterPro, AlphaFold DB and PDBe.

05 Interactions

Proteins STRING associates with ELOVL7

Waiting for the record before reading STRING.

06 Pathways

Where ELOVL7 acts, as Reactome curates it

Waiting for the record before reading UniProt and Reactome.

07 Disease associations

Diseases linked to ELOVL7

Waiting for the record before reading Open Targets and ClinGen.

08 Variants

Classified variants of ELOVL7

Waiting for the record before reading ClinVar.

09 Constraint

How much variation ELOVL7 tolerates

Waiting for the record before reading gnomAD and Open Targets.

10 Orthologs

The same gene in mouse, rat and human

Waiting for the record before reading the Alliance, NCBI, Ensembl Compara and RGD.

11 MicroRNAs

MicroRNAs hosted within ELOVL7

Waiting for the record before reading Ensembl and miRBase.

12 Long non-coding RNAs

Long non-coding RNAs at the ELOVL7 locus

Waiting for the record before reading Ensembl.

13 Literature

Papers that mention ELOVL7

Waiting for the record before reading Europe PMC.

Accession	Name	Biotype	Labels	Exons	Spliced length	Protein	Sequence
NM_024930.3matches ENST00000508821.6	transcript variant 1	protein coding	MANE Select	9	3,874 nt	281 aaNP_079206.2	Ready in a moment
XM_005248606.6matches ENST00000866637.2	transcript variant X3	protein coding model	none	8	4,561 nt	281 aaXP_005248663.1	Ready in a moment
NM_001297617.2matches ENST00000505959.6	transcript variant 3	protein coding	none	11	4,221 nt	268 aaNP_001284546.1	Ready in a moment
XM_011543651.4	Ready in a moment

Accession	Name	Biotype	Labels	Exons	Spliced length	Protein	Sequence
NM_024930.3matches ENST00000508821.6	transcript variant 1	protein coding	MANE Select	9	3,874 nt	281 aaNP_079206.2	Ready in a moment
XM_005248606.6matches ENST00000866637.2	transcript variant X3	protein coding model	none	8	4,561 nt	281 aaXP_005248663.1	Ready in a moment
NM_001297617.2matches ENST00000505959.6	transcript variant 3	protein coding	none	11	4,221 nt	268 aaNP_001284546.1	Ready in a moment
XM_011543651.4	Ready in a moment

Accession	Name	Biotype	Labels	Exons	Spliced length	Protein	Sequence
ENST00000508821.6matches NM_024930.3	ELOVL7-205	protein coding	MANE SelectEnsembl canonical	9	3,874 nt	281 aaENSP00000424123.1	Ready in a moment
ENST00000866638.2	ELOVL7-209	protein coding	none	9	4,612 nt	281 aaENSP00000536697.1	Ready in a moment
ENST00000866637.2	ELOVL7-208	protein coding	none	8	4,561 nt	281 aaENSP00000536696.1	Ready in a moment
ENST00001133880.1	ELOVL7-210	protein coding	none	9	4,194 nt	281 aaENSP00000813549.1	Ready in a moment
ENST00000505959.6	ELOVL7-203	protein coding	none	11	4,167 nt	268 aaENSP00000421043.1	Ready in a moment
ENST00000425382.6	ELOVL7-201	protein coding	none	8	4,143 nt	281 aaENSP00000402634.1	Ready in a moment
ENST00000504455.5	ELOVL7-202	nonsense mediated decay	none	7	1,034 nt	71 aaENSP00000425127.1	Ready in a moment
ENST00000511799.5	ELOVL7-206	protein coding	none	8	737 nt	165 aaENSP00000424081.1	Ready in a moment
ENST00000507047.5	ELOVL7-204	protein coding	none	8	730 nt	165 aaENSP00000426400.1	Ready in a moment
ENST00000514809.1	ELOVL7-207	nonsense mediated decay	none	7	595 nt	88 aaENSP00000422602.1	Ready in a moment

ELOVL7

What ELOVL7 does

The RNA a design targets

Where ELOVL7 is expressed

The protein ELOVL7 encodes

Proteins STRING associates with ELOVL7

Where ELOVL7 acts, as Reactome curates it

Diseases linked to ELOVL7

Classified variants of ELOVL7

How much variation ELOVL7 tolerates

The same gene in mouse, rat and human

MicroRNAs hosted within ELOVL7

Long non-coding RNAs at the ELOVL7 locus

Papers that mention ELOVL7

From ELOVL7 to a sequence that silences it

Choose the region

Cover the isoforms you mean

Think across species early

Check expression in your model

Run the controls

Pick the product

ELOVL7

What ELOVL7 does

The RNA a design targets

Where ELOVL7 is expressed

The protein ELOVL7 encodes

Proteins STRING associates with ELOVL7

Where ELOVL7 acts, as Reactome curates it

Diseases linked to ELOVL7

Classified variants of ELOVL7

How much variation ELOVL7 tolerates

The same gene in mouse, rat and human

MicroRNAs hosted within ELOVL7

Long non-coding RNAs at the ELOVL7 locus

Papers that mention ELOVL7

ELOVL7

What ELOVL7 does

Gene summary

Protein function

The RNA a design targets

RefSeq 9 transcripts

A window on one transcript

Ensembl 10 transcripts

A window on one transcript

Where ELOVL7 is expressed

The protein ELOVL7 encodes

Proteins STRING associates with ELOVL7

Where ELOVL7 acts, as Reactome curates it

Diseases linked to ELOVL7

Classified variants of ELOVL7

How much variation ELOVL7 tolerates

The same gene in mouse, rat and human

MicroRNAs hosted within ELOVL7

Long non-coding RNAs at the ELOVL7 locus

Papers that mention ELOVL7

From ELOVL7 to a sequence that silences it

Choose the region

Cover the isoforms you mean

Think across species early

Check expression in your model

Run the controls

Pick the product

Gene summary

Protein function

RefSeq 9 transcripts

A window on one transcript

Ensembl 10 transcripts

A window on one transcript