Gene Human Homo sapiens

Symbol resolved

You asked for FAM183A; that is a previous symbol, and the current HGNC symbol is CFAP144.

CFAP144

cilia and flagella associated protein 144

gene with protein product

Human CFAP144MouseRat

Reading the ortholog votes for mouse and rat.

Location: Cytogenetic band 1p34.2NCBI: 1:43,142,962-43,156,396 on the plus strand, GRCh38.p14 (GCF_000001405.40), sequence NC_000001.11, annotation GCF_000001405.40-RS_2025_08 of 2025-08-01Ensembl: 1:43,145,153-43,156,396 on the plus strand, GRCh38.p14 (GCA_000001405.29), release 116Coordinates are one-based with both ends included, as each source reports them.
Also known as: LOC440585, hCG23177
Previous symbols: FAM183A

Gene identity, from HGNC · HGNC 2026-10-02 · read 2026-10-05 ET · HGNC:34347

Silence this gene

The order page opens with CFAP144 and human filled in. The sequences are designed against the transcripts below; the price is on that page.

Order for CFAP144

sdASO, toASO or siRNA

Bring your own sequence Transcripts

For research use only. Not for use in diagnostic or therapeutic procedures.

Summary
Transcripts
Expression
Protein
Interactions
Pathways
Disease
Variants
Constraint
Orthologs
MicroRNAs
Long non-coding RNAs
Literature
Silencing this gene

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01 Summary and function

What CFAP144 does

Enables microtubule binding activity.

NCBI Gene summary

Ready in a moment

02 Transcripts and isoforms

The RNA a design targets

Reading NCBI Datasets and Ensembl.Still reading. A first read of a gene can take a while; this page waits up to 80 seconds for it, and its scripts then bring in this line, or a line saying what did not arrive.

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03 Expression by tissue

Where CFAP144 is expressed

Reading GTEx and the Human Protein Atlas.Still reading. A first read of a gene can take a while; this page waits up to 80 seconds for it, and its scripts then bring in this line, or a line saying what did not arrive.

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04 Protein

The protein CFAP144 encodes

Reading UniProt, InterPro, AlphaFold DB and PDBe.Still reading. A first read of a gene can take a while; this page waits up to 80 seconds for it, and its scripts then bring in this line, or a line saying what did not arrive.

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05 Interactions

Proteins STRING associates with CFAP144

STRING v12.0 has no protein named CFAP144 in human.

STRING

Ready in a moment

06 Pathways

Where CFAP144 acts, as Reactome curates it

Reading UniProt and Reactome.Still reading. A first read of a gene can take a while; this page waits up to 60 seconds for it, and its scripts then bring in this line, or a line saying what did not arrive.

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07 Disease associations

Diseases linked to CFAP144

Reading Open Targets and ClinGen.Still reading. A first read of a gene can take a while; this page waits up to 105 seconds for it, and its scripts then bring in this line, or a line saying what did not arrive.

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08 Variants

Classified variants of CFAP144

Reading ClinVar.Still reading. A first read of a gene can take a while; this page waits up to 60 seconds for it, and its scripts then bring in this line, or a line saying what did not arrive.

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09 Constraint

How much variation CFAP144 tolerates

Reading gnomAD and Open Targets.Still reading. A first read of a gene can take a while; this page waits up to 45 seconds for it, and its scripts then bring in this line, or a line saying what did not arrive.

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10 Orthologs

The same gene in mouse, rat and human

Reading the Alliance, NCBI, Ensembl Compara and RGD.Still reading. A first read of a gene can take a while; this page waits up to 145 seconds for it, and its scripts then bring in this line, or a line saying what did not arrive.

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11 MicroRNAs

MicroRNAs hosted within CFAP144

No annotated microRNA lies within CFAP144 in Ensembl release 116, on GRCh38.p14.

Ensembl · miRBase

Ready in a moment

12 Long non-coding RNAs

Long non-coding RNAs at the CFAP144 locus

No annotated long non-coding RNA overlaps CFAP144 in Ensembl release 116, on GRCh38.p14.

Ensembl

Ready in a moment

13 Literature

Papers that mention CFAP144

Reading Europe PMC.Still reading. A first read of a gene can take a while; this page waits up to 55 seconds for it, and its scripts then bring in this line, or a line saying what did not arrive.

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14 Silencing this gene

From CFAP144 to a sequence that silences it

The AUMsilence platform designs the sequences against the human transcripts on this page. Six decisions are yours before it does. What is written under each is AUM's guidance; the timings and the concentrations are in the usage guide below.

01
Choose the region
A knockdown oligonucleotide can sit in the 5' untranslated region, the coding sequence or the 3' untranslated region, and all three are used. The coding sequence and the 3' untranslated region are the usual first choices for an RNase H design; the 5' end near the start codon suits a steric block. The map above shows where each region sits on the isoforms it draws.
02
Cover the isoforms you mean
An exon every isoform carries silences the whole gene; an exon only some isoforms carry silences those and spares the rest. Decide which you want before a sequence is chosen, and check the reference transcript (MANE Select in human; RefSeq Select and Ensembl canonical in mouse and rat) is the one your cells express.
03
Think across species early
The orthologs panel says whether mouse and rat carry the same gene. Whether one oligonucleotide can serve two species is a sequence question, settled at design by matching the candidate against each transcript, not by the protein identity shown there.
04
Check expression in your model
A transcript that is not expressed in your cells cannot show knockdown. Confirm the gene is expressed in the cell type and condition you will use, from your own data or a reference atlas, before the order. The expression panel above gives GTEx's median per tissue for a human gene; for mouse and rat it says that no atlas is on this page yet.
05
Run the controls
A scramble control of the same chemistry, a positive control against a gene known to knock down in your cells, untreated cells, and a mock condition where a transfection reagent is used. Read knockdown at the RNA level first, then at the protein; the usage guide gives the timing and the concentrations to start from.
06
Pick the product
AUMsilence sdASO needs no transfection reagent and works in the cells that resist one. AUMsilence toASO is the transfection-optimised version of the same design, and AUMsiRNA is the siRNA route. The selection guide compares them.

Order for CFAP144 Bring your own sequence The usage guide Selection guide

For research use only. Not for use in diagnostic or therapeutic procedures.

Gene Human Homo sapiens

FAM183A

Reading the record for FAM183A from HGNC, NCBI Gene and Ensembl.Still reading. A first read of a gene can take a while; this page waits up to 115 seconds for it, and its scripts then bring in the page, or a line saying what did not arrive.

The full name, the identifiers, the location and the notes from the sources arrive with the record. Nothing is filled in ahead of it.

Order door

The door to order for FAM183A opens with the record, which decides which product it carries. The order page itself is open now.

Bring your own sequence

For research use only. Not for use in diagnostic or therapeutic procedures.

This page is still reading the record. Its scripts replace this shell with the record when it arrives; with scripts off, it stays at this shell however long you wait.

01 Summary and function

What FAM183A does

Waiting for the record before reading NCBI Gene and UniProt.

02 Transcripts and isoforms

The RNA a design targets

Waiting for the record before reading NCBI Datasets and Ensembl.

03 Expression by tissue

Where FAM183A is expressed

Waiting for the record before reading GTEx and the Human Protein Atlas.

04 Protein

The protein FAM183A encodes

Waiting for the record before reading UniProt, InterPro, AlphaFold DB and PDBe.

05 Interactions

Proteins STRING associates with FAM183A

Waiting for the record before reading STRING.

06 Pathways

Where FAM183A acts, as Reactome curates it

Waiting for the record before reading UniProt and Reactome.

07 Disease associations

Diseases linked to FAM183A

Waiting for the record before reading Open Targets and ClinGen.

08 Variants

Classified variants of FAM183A

Waiting for the record before reading ClinVar.

09 Constraint

How much variation FAM183A tolerates

Waiting for the record before reading gnomAD and Open Targets.

10 Orthologs

The same gene in mouse, rat and human

Waiting for the record before reading the Alliance, NCBI, Ensembl Compara and RGD.

11 MicroRNAs

MicroRNAs hosted within FAM183A

Waiting for the record before reading Ensembl and miRBase.

12 Long non-coding RNAs

Long non-coding RNAs at the FAM183A locus

Waiting for the record before reading Ensembl.

13 Literature

Papers that mention FAM183A

Waiting for the record before reading Europe PMC.

Accession	Name	Biotype	Labels	Exons	Spliced length	Protein	Sequence
NM_001101376.3matches ENST00000335282.5	none given	protein coding	MANE Select	4	536 nt	134 aaNP_001094846.2	Ready in a moment
XM_005270876.5matches ENST00000410048.5	transcript variant X2	protein coding model	none	4	2,739 nt	122 aaXP_005270933.1	Ready in a moment
XM_005270875.6matches ENST00000409396.5	transcript variant X1	protein coding model	none	4	584 nt	150 aaXP_005270932.1	Ready in a moment

Accession	Name	Biotype	Labels	Exons	Spliced length	Protein	Sequence
NM_001101376.3matches ENST00000335282.5	none given	protein coding	MANE Select	4	536 nt	134 aaNP_001094846.2	Ready in a moment
XM_005270876.5matches ENST00000410048.5	transcript variant X2	protein coding model	none	4	2,739 nt	122 aaXP_005270933.1	Ready in a moment
XM_005270875.6matches ENST00000409396.5	transcript variant X1	protein coding model	none	4	584 nt	150 aaXP_005270932.1	Ready in a moment

Accession	Name	Biotype	Labels	Exons	Spliced length	Protein	Sequence
ENST00000335282.5matches NM_001101376.3	CFAP144-201	protein coding	MANE SelectEnsembl canonical	4	536 nt	134 aaENSP00000334415.3	Ready in a moment
ENST00001095053.1	CFAP144-209	nonsense mediated decay	none	4	584 nt	58 aaENSP00000764859.1	Ready in a moment
ENST00000410025.5	CFAP144-204	nonsense mediated decay	none	4	530 nt	58 aaENSP00000387018.2	Ready in a moment
ENST00000410048.5	CFAP144-205	protein coding	none	4	500 nt	106 aaENSP00000387249.1	Ready in a moment
ENST00001050044.1	CFAP144-208	protein coding	none	3	452 nt	70 aaENSP00000719861.1	Ready in a moment
ENST00000409396.5	CFAP144-203	protein coding	none	4	448 nt	139 aaENSP00000387254.1	Ready in a moment
ENST00001130414.1	CFAP144-210	protein coding	none	2	426 nt	73 aaENSP00000800219.1	Ready in a moment
ENST00000940879.2	CFAP144-207	protein coding	none	3	335 nt	63 aaENSP00000610938.1	Ready in a moment
ENST00000409337.5	CFAP144-202	protein coding cds not defined	none	3	476 nt	none	Ready in a moment
ENST00000481753.1	CFAP144-206	retained intron	none	2	365 nt	none	Ready in a moment

CFAP144

What CFAP144 does

The RNA a design targets

Where CFAP144 is expressed

The protein CFAP144 encodes

Proteins STRING associates with CFAP144

Where CFAP144 acts, as Reactome curates it

Diseases linked to CFAP144

Classified variants of CFAP144

How much variation CFAP144 tolerates

The same gene in mouse, rat and human

MicroRNAs hosted within CFAP144

Long non-coding RNAs at the CFAP144 locus

Papers that mention CFAP144

From CFAP144 to a sequence that silences it

Choose the region

Cover the isoforms you mean

Think across species early

Check expression in your model

Run the controls

Pick the product

FAM183A

What FAM183A does

The RNA a design targets

Where FAM183A is expressed

The protein FAM183A encodes

Proteins STRING associates with FAM183A

Where FAM183A acts, as Reactome curates it

Diseases linked to FAM183A

Classified variants of FAM183A

How much variation FAM183A tolerates

The same gene in mouse, rat and human

MicroRNAs hosted within FAM183A

Long non-coding RNAs at the FAM183A locus

Papers that mention FAM183A

CFAP144

What CFAP144 does

Gene summary

Protein function

The RNA a design targets

RefSeq 3 transcripts

A window on one transcript

Ensembl 10 transcripts

A window on one transcript

Where CFAP144 is expressed

The protein CFAP144 encodes

Proteins STRING associates with CFAP144

Where CFAP144 acts, as Reactome curates it

Diseases linked to CFAP144

Classified variants of CFAP144

How much variation CFAP144 tolerates

The same gene in mouse, rat and human

MicroRNAs hosted within CFAP144

Long non-coding RNAs at the CFAP144 locus

Papers that mention CFAP144

From CFAP144 to a sequence that silences it

Choose the region

Cover the isoforms you mean

Think across species early

Check expression in your model

Run the controls

Pick the product

Gene summary

Protein function

RefSeq 3 transcripts

A window on one transcript

Ensembl 10 transcripts

A window on one transcript