Reading the record for MIAT from HGNC, NCBI Gene and Ensembl.Still reading. A first read of a gene can take a while; this page waits up to 115 seconds for it, and its scripts then bring in the page, or a line saying what did not arrive.
The full name, the identifiers, the location and the notes from the sources arrive with the record. Nothing is filled in ahead of it.
Order door
The door to order for MIAT opens with the record, which decides which product it carries. The order page itself is open now.
Cytogenetic band 22q12.1NCBI: 22:26,646,429-26,676,478 on the plus strand, GRCh38.p14 (GCF_000001405.40), sequence NC_000022.11, annotation GCF_000001405.40-RS_2025_08 of 2025-08-01Ensembl: 22:26,646,411-26,676,478 on the plus strand, GRCh38.p14 (GCA_000001405.29), release 116Coordinates are one-based with both ends included, as each source reports them.
This gene encodes a spliced long non-coding RNA that may constitute a… UniProt has 0 reviewed entries named MIAT in human.
NCBI Gene summary
Ready in a moment
Reading NCBI Gene and UniProt.Still reading. A first read of a gene can take a while; this page waits up to 30 seconds for it, and its scripts then bring in the panel, or a line saying what did not arrive.
02 / Transcripts and isoforms
The RNA a design targets
Reading NCBI Datasets and Ensembl.Still reading. A first read of a gene can take a while; this page waits up to 80 seconds for it, and its scripts then bring in this line, or a line saying what did not arrive.
Ready in a moment
Reading NCBI Datasets and Ensembl.Still reading. A first read of a gene can take a while; this page waits up to 80 seconds for it, and its scripts then bring in the panel, or a line saying what did not arrive.
03 / Expression by tissue
Where MIAT is expressed
54 GTEx tissues; the highest median in Pituitary, 109 TPM.
GTEx
Ready in a moment
04 / Protein
The protein MIAT encodes
UniProt did not give one reviewed entry for MIAT in human, so InterPro, AlphaFold DB and PDBe were not asked and no protein entry is shown.
UniProt
Ready in a moment
05 / Interactions
Proteins STRING associates with MIAT
Reading STRING.Still reading. A first read of a gene can take a while; this page waits up to 50 seconds for it, and its scripts then bring in this line, or a line saying what did not arrive.
Ready in a moment
06 / Pathways
Where MIAT acts, as Reactome curates it
UniProt did not give one reviewed entry for MIAT in human, so Reactome was not asked and no pathway list is shown.
UniProt
Ready in a moment
07 / Disease associations
Diseases linked to MIAT
266 Open Targets disease associations; breast cancer first, at 0.11.
Open Targets
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08 / Variants
Classified variants of MIAT
Reading ClinVar.Still reading. A first read of a gene can take a while; this page waits up to 60 seconds for it, and its scripts then bring in this line, or a line saying what did not arrive.
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09 / Constraint
How much variation MIAT tolerates
Reading gnomAD and Open Targets.Still reading. A first read of a gene can take a while; this page waits up to 45 seconds for it, and its scripts then bring in this line, or a line saying what did not arrive.
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10 / Orthologs
The same gene in mouse, rat and human
Mouse Miat by 2 of 3 votes; rat Miat by 2 of 3 votes. RGD is not answering, so the ortholog list could not be shown. Try again later. Reference 890f4e04-d92.
Alliance · NCBI · Ensembl Compara
Ready in a moment
11 /MicroRNAs
MicroRNAs hosted within MIAT
Reading Ensembl and miRBase.Still reading. A first read of a gene can take a while; this page waits up to 110 seconds for it, and its scripts then bring in this line, or a line saying what did not arrive.
Ready in a moment
12 / Long non-coding RNAs
Long non-coding RNAs at the MIAT locus
Reading Ensembl.Still reading. A first read of a gene can take a while; this page waits up to 110 seconds for it, and its scripts then bring in this line, or a line saying what did not arrive.
Ready in a moment
13 / Literature
Papers that mention MIAT
Reading Europe PMC.Still reading. A first read of a gene can take a while; this page waits up to 55 seconds for it, and its scripts then bring in this line, or a line saying what did not arrive.
Ready in a moment
14 / Silencing this gene
From MIAT to a sequence that silences it
This is a long non-coding RNA gene. The order page opens with MIAT and human filled in, on AUMlnc™ sdASO™, with AUMlnc toASO beside it, and the price on that page. Its long non-coding RNA page sets out the steps that come first, each with the sources it rests on.
For research use only. Not for use in diagnostic or therapeutic procedures.
Gene summary
This gene encodes a spliced long non-coding RNA that may constitute a component of the nuclear matrix. Altered expression of this locus has been reported to be associated with a susceptibility to myocardial infarction. It has also been proposed that pathways involving this transcript may contribute to the pathophysiology of schizophrenia. A similar gene in mouse has been associated with retinal cell fate determination. Alternatively spliced transcript variants have been identified.
Provided by RefSeq, Dec 2014, through NCBI Gene. NCBI disclaimer
Protein function
Not available
UniProt has 0 reviewed entries named MIAT in human.
NCBI Gene summary · NCBI Gene annotation RS_2025_08 · read · NCBI Gene 440823Data from NCBI, provided as is; NCBI's policies and disclaimers apply.
STRING v12.0 has no protein named MIAT in human.
STRING
No annotated microRNA lies within MIAT in Ensembl release 116, on GRCh38.p14.
Ensembl · miRBase
3 long non-coding RNA genes overlap MIAT in Ensembl release 116, 2 antisense: MIATNB and 2 without a symbol.
3,216 PubMed-indexed papers mention MIAT at Europe PMC, newest first. Europe PMC ignores letter case, so the count also covers another species' symbol spelled with the same letters.
Europe PMC
20 RefSeq and 50 Ensembl transcripts on GRCh38.p14; MANE Select NR_033320.3.
NCBI Datasets · Ensembl
Placed on GRCh38.p14 (GCF_000001405.40). MANE Select marks the one transcript RefSeq and Ensembl agree is the reference for this gene.
RefSeq 20 transcripts
coding sequence, tall
untranslated region, thin
non-coding exon
intron, fixed width
Genomic strand: plus. Drawn 5' to 3', so exon 1 sits at the left here and at the lowest coordinate on the chromosome.
NR_033320.3NR_033320.3MANE Select
NR_185985.1NR_185985.1
A window on one transcript
One pixel of the map above stands for several bases, and a block too short to see is drawn wider than its own scale, so the map chooses a region and the sequence here chooses the window. Click an exon on a row of the map, or drag across a row; then set the exact start and end below.
These controls are ready in a moment.
No transcript is chosen.
Once a window is chosen this panel shows its length, its G and C count as a percentage of that length, the letters it is made of, the exons it falls in, whether it crosses a junction, and its antisense strand.
NCBI Datasets, RefSeq transcripts · NCBI Datasets 18.38.0; GCF_000001405.40-RS_2025_08 · read · NCBI Gene 440823Data from NCBI, provided as is; NCBI's policies and disclaimers apply.
Ensembl 50 transcripts
A window on one transcript
One pixel of the map above stands for several bases, and a block too short to see is drawn wider than its own scale, so the map chooses a region and the sequence here chooses the window. Click an exon on a row of the map, or drag across a row; then set the exact start and end below.
These controls are ready in a moment.
No transcript is chosen.
Once a window is chosen this panel shows its length, its G and C count as a percentage of that length, the letters it is made of, the exons it falls in, whether it crosses a junction, and its antisense strand.
Lengths are spliced lengths, as each source states them. Exon ranks follow the strand: on a minus-strand gene exon 1 has the highest genomic coordinate. Reference assembly for human: GRCh38.
NR_185984.1NR_185984.1
NR_185987.1NR_185987.1
NR_185983.1NR_185983.1
NR_185986.1NR_185986.1
NR_185993.1NR_185993.1
NR_185982.1NR_185982.1
NR_185990.1NR_185990.1
NR_185991.1NR_185991.1
NR_185988.1NR_185988.1
NR_185989.1NR_185989.1
NR_185998.1NR_185998.1
NR_185995.1NR_185995.1
NR_003491.4NR_003491.4
NR_185996.1NR_185996.1
NR_185994.1NR_185994.1
NR_185997.1NR_185997.1
NR_033319.3NR_033319.3
NR_033321.3NR_033321.3
scale
Drawn 5' to 3' from each transcript's exons as placed on the reference assembly; exon 1 is the 5' exon on the transcript's own strand. Exon blocks are to scale with each other; introns are drawn at one fixed width whatever their length, so the map is not to scale along the chromosome. Numbers are exon ranks along the strand; a rank is omitted where the exon is too narrow to carry it.
Drawn 5' to 3' from each transcript's exons as placed on the reference assembly; exon 1 is the 5' exon on the transcript's own strand. Exon blocks are to scale with each other; introns are drawn at one fixed width whatever their length, so the map is not to scale along the chromosome. Numbers are exon ranks along the strand; a rank is omitted where the exon is too narrow to carry it.
