Gene Human Homo sapiens

RN7SL186P

RNA, 7SL, cytoplasmic 186, pseudogene

pseudogene

Human RN7SL186PMouseRat

Reading the ortholog votes for mouse and rat.

HGNC lists no MANE Select pair for this gene.

Location: Cytogenetic band 1p36.12NCBI: 1:22,010,650-22,010,946 on the plus strand, GRCh38.p14 (GCF_000001405.40), sequence NC_000001.11, annotation GCF_000001405.40-RS_2025_08 of 2025-08-01Ensembl: no location was read.Coordinates are one-based with both ends included, as each source reports them.

Gene identity, from HGNC · HGNC 2026-09-18 · read 2026-09-24 ET · HGNC:46202

Notes from the sources

Ensembl did not answer (upstream error).
Ensembl did not answer (upstream error); the Ensembl location and release are missing

Silence this gene

The order page opens with RN7SL186P and human filled in. The sequences are designed against the transcripts below; the price is on that page.

Order for RN7SL186P

sdASO, toASO or siRNA, chosen on the next page

Bring your own sequence Transcripts

For research use only. Not for use in diagnostic or therapeutic procedures.

Summary
Transcripts
Expression
Protein
Interactions
Pathways
Disease
Variants
Constraint
Orthologs
MicroRNAs
Long non-coding RNAs
Literature
Silencing this gene

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01 Summary and function

What RN7SL186P does

NCBI Gene answered in a shape this page does not read, so nothing is shown for the summary. Reference 8b0bc2a1-853.

Ready in a moment

02 Transcripts and isoforms

The RNA a design targets

Reading NCBI Datasets and Ensembl.Still reading. A first read of a gene can take a while; this page waits up to 80 seconds for it, and its scripts then bring in this line, or a line saying what did not arrive.

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03 Expression by tissue

Where RN7SL186P is expressed

Reading GTEx and the Human Protein Atlas.Still reading. A first read of a gene can take a while; this page waits up to 80 seconds for it, and its scripts then bring in this line, or a line saying what did not arrive.

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04 Protein

The protein RN7SL186P encodes

UniProt did not give one reviewed entry for RN7SL186P in human, so InterPro, AlphaFold DB and PDBe were not asked and no protein entry is shown.

UniProt

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05 Interactions

Proteins STRING associates with RN7SL186P

Reading STRING.Still reading. A first read of a gene can take a while; this page waits up to 50 seconds for it, and its scripts then bring in this line, or a line saying what did not arrive.

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06 Pathways

Where RN7SL186P acts, as Reactome curates it

UniProt did not give one reviewed entry for RN7SL186P in human, so Reactome was not asked and no pathway list is shown.

UniProt

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07 Disease associations

Diseases linked to RN7SL186P

Reading Open Targets and ClinGen.Still reading. A first read of a gene can take a while; this page waits up to 105 seconds for it, and its scripts then bring in this line, or a line saying what did not arrive.

Ready in a moment

08 Variants

Classified variants of RN7SL186P

ClinVar holds no record for RN7SL186P.

ClinVar

Ready in a moment

09 Constraint

How much variation RN7SL186P tolerates

Reading gnomAD and Open Targets.Still reading. A first read of a gene can take a while; this page waits up to 45 seconds for it, and its scripts then bring in this line, or a line saying what did not arrive.

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10 Orthologs

The same gene in mouse, rat and human

Reading the Alliance, NCBI, Ensembl Compara and RGD.Still reading. A first read of a gene can take a while; this page waits up to 145 seconds for it, and its scripts then bring in this line, or a line saying what did not arrive.

Ready in a moment

11 MicroRNAs

MicroRNAs hosted within RN7SL186P

Ensembl is not answering, so the non-coding annotation could not be shown. Try again later. Reference 06b134d7-ef8.

Ready in a moment

12 Long non-coding RNAs

Long non-coding RNAs at the RN7SL186P locus

Ensembl is not answering, so the non-coding annotation could not be shown. Try again later. Reference 06b134d7-ef8.

Ready in a moment

13 Literature

Papers that mention RN7SL186P

Europe PMC finds no PubMed-indexed paper mentioning this symbol.

Europe PMC

Ready in a moment

14 Silencing this gene

From RN7SL186P to a sequence that silences it

The AUMsilence platform designs the sequences against the human transcripts on this page. Six decisions are yours before it does. What is written under each is AUM's guidance; the timings and the concentrations are in the usage guide below.

01
Choose the region
A knockdown oligonucleotide can sit in the 5' untranslated region, the coding sequence or the 3' untranslated region, and all three are used. The coding sequence and the 3' untranslated region are the usual first choices for an RNase H design; the 5' end near the start codon suits a steric block. The map above shows where each region sits on the isoforms it draws.
02
Cover the isoforms you mean
An exon every isoform carries silences the whole gene; an exon only some isoforms carry silences those and spares the rest. Decide which you want before a sequence is chosen, and check the reference transcript (MANE Select in human; RefSeq Select and Ensembl canonical in mouse and rat) is the one your cells express.
03
Think across species early
The orthologs panel says whether mouse and rat carry the same gene. Whether one oligonucleotide can serve two species is a sequence question, settled at design by matching the candidate against each transcript, not by the protein identity shown there.
04
Check expression in your model
A transcript that is not expressed in your cells cannot show knockdown. Confirm the gene is expressed in the cell type and condition you will use, from your own data or a reference atlas, before the order. The expression panel above gives GTEx's median per tissue for a human gene; for mouse and rat it says that no atlas is on this page yet.
05
Run the controls
A scramble control of the same chemistry, a positive control against a gene known to knock down in your cells, untreated cells, and a mock condition where a transfection reagent is used. Read knockdown at the RNA level first, then at the protein; the usage guide gives the timing and the concentrations to start from.
06
Pick the product
AUMsilence sdASO needs no transfection reagent and works in the cells that resist one. AUMsilence toASO is the transfection-optimised version of the same design, and AUMsiRNA is the siRNA route. The selection guide compares them.

Order for RN7SL186P Bring your own sequence The usage guide Selection guide

For research use only. Not for use in diagnostic or therapeutic procedures.

Gene Human Homo sapiens

RN7SL186P

Reading the record for RN7SL186P from HGNC, NCBI Gene and Ensembl.Still reading. A first read of a gene can take a while; this page waits up to 115 seconds for it, and its scripts then bring in the page, or a line saying what did not arrive.

The full name, the identifiers, the location and the notes from the sources arrive with the record. Nothing is filled in ahead of it.

Order door

The door to order for RN7SL186P opens with the record, which decides which product it carries. The order page itself is open now.

Bring your own sequence

For research use only. Not for use in diagnostic or therapeutic procedures.

This page is still reading the record. Its scripts replace this shell with the record when it arrives; with scripts off, it stays at this shell however long you wait.

01 Summary and function

What RN7SL186P does

Waiting for the record before reading NCBI Gene and UniProt.

02 Transcripts and isoforms

The RNA a design targets

Waiting for the record before reading NCBI Datasets and Ensembl.

03 Expression by tissue

Where RN7SL186P is expressed

Waiting for the record before reading GTEx and the Human Protein Atlas.

04 Protein

The protein RN7SL186P encodes

Waiting for the record before reading UniProt, InterPro, AlphaFold DB and PDBe.

05 Interactions

Proteins STRING associates with RN7SL186P

Waiting for the record before reading STRING.

06 Pathways

Where RN7SL186P acts, as Reactome curates it

Waiting for the record before reading UniProt and Reactome.

07 Disease associations

Diseases linked to RN7SL186P

Waiting for the record before reading Open Targets and ClinGen.

08 Variants

Classified variants of RN7SL186P

Waiting for the record before reading ClinVar.

09 Constraint

How much variation RN7SL186P tolerates

Waiting for the record before reading gnomAD and Open Targets.

10 Orthologs

The same gene in mouse, rat and human

Waiting for the record before reading the Alliance, NCBI, Ensembl Compara and RGD.

11 MicroRNAs

MicroRNAs hosted within RN7SL186P

Waiting for the record before reading Ensembl and miRBase.

12 Long non-coding RNAs

Long non-coding RNAs at the RN7SL186P locus

Waiting for the record before reading Ensembl.

13 Literature

Papers that mention RN7SL186P

Waiting for the record before reading Europe PMC.

RN7SL186P

RNA, 7SL, cytoplasmic 186, pseudogene

pseudogene

Mouse: no ortholog is named for this gene: the Alliance and NCBI answered and named none; Ensembl Compara did not answer (upstream error, reference c344a8fa-915).
Rat: no ortholog is named for this gene: the Alliance and NCBI answered and named none; Ensembl Compara did not answer (upstream error, reference c344a8fa-915).

Human RN7SL186PMouseRat

Reading the ortholog votes for mouse and rat.

HGNC lists no MANE Select pair for this gene.

Location

Cytogenetic band 1p36.12NCBI: 1:22,010,650-22,010,946 on the plus strand, GRCh38.p14 (GCF_000001405.40), sequence NC_000001.11, annotation GCF_000001405.40-RS_2025_08 of 2025-08-01Ensembl: no location was read.Coordinates are one-based with both ends included, as each source reports them.

Gene identity, from HGNC · HGNC 2026-09-18 · read 2026-09-24 ET · HGNC:46202

Notes from the sources

Ensembl did not answer (upstream error).
Ensembl did not answer (upstream error); the Ensembl location and release are missing

From RN7SL186P to a sequence that silences it

Choose the region

A knockdown oligonucleotide can sit in the 5' untranslated region, the coding sequence or the 3' untranslated region, and all three are used. The coding sequence and the 3' untranslated region are the usual first choices for an RNase H design; the 5' end near the start codon suits a steric block. The map above shows where each region sits on the isoforms it draws.

Cover the isoforms you mean

An exon every isoform carries silences the whole gene; an exon only some isoforms carry silences those and spares the rest. Decide which you want before a sequence is chosen, and check the reference transcript (MANE Select in human; RefSeq Select and Ensembl canonical in mouse and rat) is the one your cells express.

Think across species early

The orthologs panel says whether mouse and rat carry the same gene. Whether one oligonucleotide can serve two species is a sequence question, settled at design by matching the candidate against each transcript, not by the protein identity shown there.

Check expression in your model

A transcript that is not expressed in your cells cannot show knockdown. Confirm the gene is expressed in the cell type and condition you will use, from your own data or a reference atlas, before the order. The expression panel above gives GTEx's median per tissue for a human gene; for mouse and rat it says that no atlas is on this page yet.

Run the controls

A scramble control of the same chemistry, a positive control against a gene known to knock down in your cells, untreated cells, and a mock condition where a transfection reagent is used. Read knockdown at the RNA level first, then at the protein; the usage guide gives the timing and the concentrations to start from.

Pick the product

AUMsilence sdASO needs no transfection reagent and works in the cells that resist one. AUMsilence toASO is the transfection-optimised version of the same design, and AUMsiRNA is the siRNA route. The selection guide compares them.

For research use only. Not for use in diagnostic or therapeutic procedures.

RN7SL186P

What RN7SL186P does

The RNA a design targets

Where RN7SL186P is expressed

The protein RN7SL186P encodes

Proteins STRING associates with RN7SL186P

Where RN7SL186P acts, as Reactome curates it

Diseases linked to RN7SL186P

Classified variants of RN7SL186P

How much variation RN7SL186P tolerates

The same gene in mouse, rat and human

MicroRNAs hosted within RN7SL186P

Long non-coding RNAs at the RN7SL186P locus

Papers that mention RN7SL186P

From RN7SL186P to a sequence that silences it

Choose the region

Cover the isoforms you mean

Think across species early

Check expression in your model

Run the controls

Pick the product

RN7SL186P

What RN7SL186P does

The RNA a design targets

Where RN7SL186P is expressed

The protein RN7SL186P encodes

Proteins STRING associates with RN7SL186P

Where RN7SL186P acts, as Reactome curates it

Diseases linked to RN7SL186P

Classified variants of RN7SL186P

How much variation RN7SL186P tolerates

The same gene in mouse, rat and human

MicroRNAs hosted within RN7SL186P

Long non-coding RNAs at the RN7SL186P locus

Papers that mention RN7SL186P

RN7SL186P

What RN7SL186P does

The RNA a design targets

RefSeq 0 transcripts

Ensembl 0 transcripts

Where RN7SL186P is expressed

The protein RN7SL186P encodes

Proteins STRING associates with RN7SL186P

Where RN7SL186P acts, as Reactome curates it

Diseases linked to RN7SL186P

Classified variants of RN7SL186P

How much variation RN7SL186P tolerates

The same gene in mouse, rat and human

MicroRNAs hosted within RN7SL186P

Long non-coding RNAs at the RN7SL186P locus

Papers that mention RN7SL186P

From RN7SL186P to a sequence that silences it

Choose the region

Cover the isoforms you mean

Think across species early

Check expression in your model

Run the controls

Pick the product

RefSeq 0 transcripts

Ensembl 0 transcripts