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Gene Human Homo sapiens

SPAST

Reading the record for SPAST from HGNC, NCBI Gene and Ensembl.Still reading. A first read of a gene can take a while; this page waits up to 115 seconds for it, and its scripts then bring in the page, or a line saying what did not arrive.

The full name, the identifiers, the location and the notes from the sources arrive with the record. Nothing is filled in ahead of it.

Order door

The door to order for SPAST opens with the record, which decides which product it carries. The order page itself is open now.

Bring your own sequence

For research use only. Not for use in diagnostic or therapeutic procedures.

01 Summary and function

What SPAST does

Waiting for the record before reading NCBI Gene and UniProt.

02 Transcripts and isoforms

The RNA a design targets

Waiting for the record before reading NCBI Datasets and Ensembl.

03 Expression by tissue

Where SPAST is expressed

Waiting for the record before reading GTEx and the Human Protein Atlas.

04 Protein

The protein SPAST encodes

Waiting for the record before reading UniProt, InterPro, AlphaFold DB and PDBe.

05 Interactions

Proteins STRING associates with SPAST

Waiting for the record before reading STRING.

06 Pathways

Where SPAST acts, as Reactome curates it

Waiting for the record before reading UniProt and Reactome.

07 Disease associations

Diseases linked to SPAST

Waiting for the record before reading Open Targets and ClinGen.

08 Variants

Classified variants of SPAST

Waiting for the record before reading ClinVar.

09 Constraint

How much variation SPAST tolerates

Waiting for the record before reading gnomAD and Open Targets.

10 Orthologs

The same gene in mouse, rat and human

Waiting for the record before reading the Alliance, NCBI, Ensembl Compara and RGD.

11 MicroRNAs

MicroRNAs hosted within SPAST

Waiting for the record before reading Ensembl and miRBase.

12 Long non-coding RNAs

Long non-coding RNAs at the SPAST locus

Waiting for the record before reading Ensembl.

13 Literature

Papers that mention SPAST

Waiting for the record before reading Europe PMC.