Gene Human Homo sapiens

TRAJ32

T cell receptor alpha joining 32

T cell receptor gene

Rat: no ortholog is named for this gene: the Alliance, NCBI and Ensembl Compara answered and named none.

HGNC lists no MANE Select pair for this gene.

Location: Cytogenetic band 14q11.2NCBI: 14:22,509,341-22,509,406 on the plus strand, GRCh38.p14 (GCF_000001405.40), sequence NC_000014.9, annotation GCF_000001405.40-RS_2025_08 of 2025-08-01Ensembl: 14:22,509,341-22,509,406 on the plus strand, GRCh38.p14 (GCA_000001405.29), release 116Coordinates are one-based with both ends included, as each source reports them.

Gene identity, from HGNC · HGNC 2026-10-02 · read 2026-10-05 ET · HGNC:12062

Silence this gene

The order page opens with TRAJ32 and human filled in. The sequences are designed against the transcripts below; the price is on that page.

Order for TRAJ32

sdASO, toASO or siRNA

Bring your own sequence Transcripts

For research use only. Not for use in diagnostic or therapeutic procedures.

Summary
Transcripts
Expression
Protein
Interactions
Pathways
Disease
Variants
Constraint
Orthologs
MicroRNAs
Long non-coding RNAs
Literature
Silencing this gene

A line below that says it is reading needs JavaScript to be replaced: with scripts off, it stays at that line however long you wait. Opening a card also needs JavaScript.

Ready in a moment

01 Summary and function

What TRAJ32 does

NCBI Gene answered in a shape this page does not read, so nothing is shown for the summary. Reference 1d92c1df-19a.

Ready in a moment

02 Transcripts and isoforms

The RNA a design targets

0 RefSeq and 1 Ensembl transcript on GRCh38.p14; Ensembl canonical ENST00000390505.1.

NCBI Datasets · Ensembl

Ready in a moment

03 Expression by tissue

Where TRAJ32 is expressed

Reading GTEx and the Human Protein Atlas.Still reading. A first read of a gene can take a while; this page waits up to 80 seconds for it, and its scripts then bring in this line, or a line saying what did not arrive.

Ready in a moment

04 Protein

The protein TRAJ32 encodes

UniProt did not give one reviewed entry for TRAJ32 in human, so InterPro, AlphaFold DB and PDBe were not asked and no protein entry is shown.

UniProt

Ready in a moment

05 Interactions

Proteins STRING associates with TRAJ32

STRING v12.0 has no protein named TRAJ32 in human.

STRING

Ready in a moment

06 Pathways

Where TRAJ32 acts, as Reactome curates it

UniProt did not give one reviewed entry for TRAJ32 in human, so Reactome was not asked and no pathway list is shown.

UniProt

Ready in a moment

07 Disease associations

Diseases linked to TRAJ32

2 Open Targets disease associations; COVID-19 first, at 0.00.

Open Targets

Ready in a moment

08 Variants

Classified variants of TRAJ32

Reading ClinVar.Still reading. A first read of a gene can take a while; this page waits up to 60 seconds for it, and its scripts then bring in this line, or a line saying what did not arrive.

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09 Constraint

How much variation TRAJ32 tolerates

pLI none and LOEUF none in gnomAD v4 (GRCh38).

gnomAD

Ready in a moment

10 Orthologs

The same gene in mouse, rat and human

Mouse Traj32 by 1 of 3 votes; rat: no ortholog named by the 3 votes that answered. RGD is not answering, so the ortholog list could not be shown. Try again later. Reference 051d08ae-fae.

Alliance · NCBI · Ensembl Compara

Ready in a moment

11 MicroRNAs

MicroRNAs hosted within TRAJ32

No annotated microRNA lies within TRAJ32 in Ensembl release 116, on GRCh38.p14.

Ensembl · miRBase

Ready in a moment

12 Long non-coding RNAs

Long non-coding RNAs at the TRAJ32 locus

No annotated long non-coding RNA overlaps TRAJ32 in Ensembl release 116, on GRCh38.p14.

Ensembl

Ready in a moment

13 Literature

Papers that mention TRAJ32

Reading Europe PMC.Still reading. A first read of a gene can take a while; this page waits up to 55 seconds for it, and its scripts then bring in this line, or a line saying what did not arrive.

Ready in a moment

14 Silencing this gene

From TRAJ32 to a sequence that silences it

The AUMsilence platform designs the sequences against the human transcripts on this page. Six decisions are yours before it does. What is written under each is AUM's guidance; the timings and the concentrations are in the usage guide below.

01
Choose the region
A knockdown oligonucleotide can sit in the 5' untranslated region, the coding sequence or the 3' untranslated region, and all three are used. The coding sequence and the 3' untranslated region are the usual first choices for an RNase H design; the 5' end near the start codon suits a steric block. The map above shows where each region sits on the isoforms it draws.
02
Cover the isoforms you mean
An exon every isoform carries silences the whole gene; an exon only some isoforms carry silences those and spares the rest. Decide which you want before a sequence is chosen, and check the reference transcript (MANE Select in human; RefSeq Select and Ensembl canonical in mouse and rat) is the one your cells express.
03
Think across species early
The orthologs panel says whether mouse and rat carry the same gene. Whether one oligonucleotide can serve two species is a sequence question, settled at design by matching the candidate against each transcript, not by the protein identity shown there.
04
Check expression in your model
A transcript that is not expressed in your cells cannot show knockdown. Confirm the gene is expressed in the cell type and condition you will use, from your own data or a reference atlas, before the order. The expression panel above gives GTEx's median per tissue for a human gene; for mouse and rat it says that no atlas is on this page yet.
05
Run the controls
A scramble control of the same chemistry, a positive control against a gene known to knock down in your cells, untreated cells, and a mock condition where a transfection reagent is used. Read knockdown at the RNA level first, then at the protein; the usage guide gives the timing and the concentrations to start from.
06
Pick the product
AUMsilence sdASO needs no transfection reagent and works in the cells that resist one. AUMsilence toASO is the transfection-optimised version of the same design, and AUMsiRNA is the siRNA route. The selection guide compares them.

Order for TRAJ32 Bring your own sequence The usage guide Selection guide

For research use only. Not for use in diagnostic or therapeutic procedures.

Gene Human Homo sapiens

TRAJ32

Reading the record for TRAJ32 from HGNC, NCBI Gene and Ensembl.Still reading. A first read of a gene can take a while; this page waits up to 115 seconds for it, and its scripts then bring in the page, or a line saying what did not arrive.

The full name, the identifiers, the location and the notes from the sources arrive with the record. Nothing is filled in ahead of it.

Order door

The door to order for TRAJ32 opens with the record, which decides which product it carries. The order page itself is open now.

Bring your own sequence

For research use only. Not for use in diagnostic or therapeutic procedures.

This page is still reading the record. Its scripts replace this shell with the record when it arrives; with scripts off, it stays at this shell however long you wait.

01 Summary and function

What TRAJ32 does

Waiting for the record before reading NCBI Gene and UniProt.

02 Transcripts and isoforms

The RNA a design targets

Waiting for the record before reading NCBI Datasets and Ensembl.

03 Expression by tissue

Where TRAJ32 is expressed

Waiting for the record before reading GTEx and the Human Protein Atlas.

04 Protein

The protein TRAJ32 encodes

Waiting for the record before reading UniProt, InterPro, AlphaFold DB and PDBe.

05 Interactions

Proteins STRING associates with TRAJ32

Waiting for the record before reading STRING.

06 Pathways

Where TRAJ32 acts, as Reactome curates it

Waiting for the record before reading UniProt and Reactome.

07 Disease associations

Diseases linked to TRAJ32

Waiting for the record before reading Open Targets and ClinGen.

08 Variants

Classified variants of TRAJ32

Waiting for the record before reading ClinVar.

09 Constraint

How much variation TRAJ32 tolerates

Waiting for the record before reading gnomAD and Open Targets.

10 Orthologs

The same gene in mouse, rat and human

Waiting for the record before reading the Alliance, NCBI, Ensembl Compara and RGD.

11 MicroRNAs

MicroRNAs hosted within TRAJ32

Waiting for the record before reading Ensembl and miRBase.

12 Long non-coding RNAs

Long non-coding RNAs at the TRAJ32 locus

Waiting for the record before reading Ensembl.

13 Literature

Papers that mention TRAJ32

Waiting for the record before reading Europe PMC.

TRAJ32

T cell receptor alpha joining 32

T cell receptor gene

Rat: no ortholog is named for this gene: the Alliance, NCBI and Ensembl Compara answered and named none.

HGNC lists no MANE Select pair for this gene.

Location

Cytogenetic band 14q11.2NCBI: 14:22,509,341-22,509,406 on the plus strand, GRCh38.p14 (GCF_000001405.40), sequence NC_000014.9, annotation GCF_000001405.40-RS_2025_08 of 2025-08-01Ensembl: 14:22,509,341-22,509,406 on the plus strand, GRCh38.p14 (GCA_000001405.29), release 116Coordinates are one-based with both ends included, as each source reports them.

Gene identity, from HGNC · HGNC 2026-10-02 · read 2026-10-05 ET · HGNC:12062

Ensembl transcripts of this gene
Accession	Name	Biotype	Labels	Exons	Spliced length	Protein	Sequence
ENST00000390505.1	TRAJ32-201	tr j gene	Ensembl canonical	1	66 nt	22 aaENSP00000451503.1	Ready in a moment

Accession

Name

Biotype

Labels

Exons

Spliced length

Protein

Sequence

ENST00000390505.1

TRAJ32-201

tr j gene

Ensembl canonical

66 nt

22 aaENSP00000451503.1

Ready in a moment

From TRAJ32 to a sequence that silences it

Choose the region

A knockdown oligonucleotide can sit in the 5' untranslated region, the coding sequence or the 3' untranslated region, and all three are used. The coding sequence and the 3' untranslated region are the usual first choices for an RNase H design; the 5' end near the start codon suits a steric block. The map above shows where each region sits on the isoforms it draws.

Cover the isoforms you mean

An exon every isoform carries silences the whole gene; an exon only some isoforms carry silences those and spares the rest. Decide which you want before a sequence is chosen, and check the reference transcript (MANE Select in human; RefSeq Select and Ensembl canonical in mouse and rat) is the one your cells express.

Think across species early

The orthologs panel says whether mouse and rat carry the same gene. Whether one oligonucleotide can serve two species is a sequence question, settled at design by matching the candidate against each transcript, not by the protein identity shown there.

Check expression in your model

A transcript that is not expressed in your cells cannot show knockdown. Confirm the gene is expressed in the cell type and condition you will use, from your own data or a reference atlas, before the order. The expression panel above gives GTEx's median per tissue for a human gene; for mouse and rat it says that no atlas is on this page yet.

Run the controls

A scramble control of the same chemistry, a positive control against a gene known to knock down in your cells, untreated cells, and a mock condition where a transfection reagent is used. Read knockdown at the RNA level first, then at the protein; the usage guide gives the timing and the concentrations to start from.

Pick the product

AUMsilence sdASO needs no transfection reagent and works in the cells that resist one. AUMsilence toASO is the transfection-optimised version of the same design, and AUMsiRNA is the siRNA route. The selection guide compares them.

For research use only. Not for use in diagnostic or therapeutic procedures.

Ensembl transcripts of this gene
Accession	Name	Biotype	Labels	Exons	Spliced length	Protein	Sequence
ENST00000390505.1	TRAJ32-201	tr j gene	Ensembl canonical	1	66 nt	22 aaENSP00000451503.1	Ready in a moment

Accession

Name

Biotype

Labels

Exons

Spliced length

Protein

Sequence

ENST00000390505.1

TRAJ32-201

tr j gene

Ensembl canonical

66 nt

22 aaENSP00000451503.1

Ready in a moment

TRAJ32

What TRAJ32 does

The RNA a design targets

Where TRAJ32 is expressed

The protein TRAJ32 encodes

Proteins STRING associates with TRAJ32

Where TRAJ32 acts, as Reactome curates it

Diseases linked to TRAJ32

Classified variants of TRAJ32

How much variation TRAJ32 tolerates

The same gene in mouse, rat and human

MicroRNAs hosted within TRAJ32

Long non-coding RNAs at the TRAJ32 locus

Papers that mention TRAJ32

From TRAJ32 to a sequence that silences it

Choose the region

Cover the isoforms you mean

Think across species early

Check expression in your model

Run the controls

Pick the product

TRAJ32

What TRAJ32 does

The RNA a design targets

Where TRAJ32 is expressed

The protein TRAJ32 encodes

Proteins STRING associates with TRAJ32

Where TRAJ32 acts, as Reactome curates it

Diseases linked to TRAJ32

Classified variants of TRAJ32

How much variation TRAJ32 tolerates

The same gene in mouse, rat and human

MicroRNAs hosted within TRAJ32

Long non-coding RNAs at the TRAJ32 locus

Papers that mention TRAJ32

TRAJ32

What TRAJ32 does

The RNA a design targets

RefSeq 0 transcripts

Ensembl 1 transcript

A window on one transcript

Where TRAJ32 is expressed

The protein TRAJ32 encodes

Proteins STRING associates with TRAJ32

Where TRAJ32 acts, as Reactome curates it

Diseases linked to TRAJ32

Classified variants of TRAJ32

How much variation TRAJ32 tolerates

The same gene in mouse, rat and human

MicroRNAs hosted within TRAJ32

Long non-coding RNAs at the TRAJ32 locus

Papers that mention TRAJ32

From TRAJ32 to a sequence that silences it

Choose the region

Cover the isoforms you mean

Think across species early

Check expression in your model

Run the controls

Pick the product

RefSeq 0 transcripts

Ensembl 1 transcript

A window on one transcript