Gene Mouse Mus musculus

2610524H06Rik

RIKEN cDNA 2610524H06 gene

protein coding

HumanMouse 2610524H06RikRat

Reading the ortholog votes for human and rat.

HGNC and MANE Select: not available for mouse. HGNC names human genes; MGI is the authority here, and MANE Select is defined for human transcripts only.

Location: Cytogenetic band 5 FNCBI: 5:114,959,998-114,961,529 on the minus strand, GRCm39 (GCF_000001635.27), sequence NC_000071.7, annotation GCF_000001635.27-RS_2024_02 of 2024-02-01Ensembl: 5:114,928,443-114,961,565 on the minus strand, GRCm39 (GCA_000001635.9), release 116Coordinates are one-based with both ends included, as each source reports them.

Gene identity, from NCBI Datasets · NCBI Datasets 18.38.0 · read 2026-10-02 ET · MGI:2447819Data from NCBI, provided as is; NCBI's policies and disclaimers apply.

Notes from the sources

Ensembl names this gene Gm57857

Silence this gene

The order page opens with 2610524H06Rik and mouse filled in. The sequences are designed against the transcripts below; the price is on that page.

Order for 2610524H06Rik

sdASO, toASO or siRNA

Bring your own sequence Transcripts

For research use only. Not for use in diagnostic or therapeutic procedures.

Summary
Transcripts
Expression
Protein
Interactions
Pathways
Disease
Variants
Constraint
Orthologs
MicroRNAs
Long non-coding RNAs
Literature
Silencing this gene

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Ready in a moment

01 Summary and function

What 2610524H06Rik does

NCBI Gene carries no curated summary for this gene. UniProt has 0 reviewed entries named 2610524H06Rik in mouse.

NCBI Gene summary

Ready in a moment

02 Transcripts and isoforms

The RNA a design targets

Reading NCBI Datasets and Ensembl.Still reading. A first read of a gene can take a while; this page waits up to 80 seconds for it, and its scripts then bring in this line, or a line saying what did not arrive.

Ready in a moment

03 Expression by tissue

Where 2610524H06Rik is expressed

Expression by tissue: not available for mouse. GTEx holds human tissues only, and the Human Protein Atlas is keyed on human genes.

Ready in a moment

04 Protein

The protein 2610524H06Rik encodes

UniProt did not give one reviewed entry for 2610524H06Rik in mouse, so InterPro, AlphaFold DB and PDBe were not asked and no protein entry is shown.

UniProt

Ready in a moment

05 Interactions

Proteins STRING associates with 2610524H06Rik

Reading STRING.Still reading. A first read of a gene can take a while; this page waits up to 50 seconds for it, and its scripts then bring in this line, or a line saying what did not arrive.

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06 Pathways

Where 2610524H06Rik acts, as Reactome curates it

UniProt did not give one reviewed entry for 2610524H06Rik in mouse, so Reactome was not asked and no pathway list is shown.

UniProt

Ready in a moment

07 Disease associations

Diseases linked to 2610524H06Rik

Disease associations: not available for mouse. Open Targets and ClinGen curate human genes only. The human ortholog's page carries the associations.

Ready in a moment

08 Variants

Classified variants of 2610524H06Rik

Clinical variants: not available for mouse. ClinVar holds human variants only.

Ready in a moment

09 Constraint

How much variation 2610524H06Rik tolerates

Constraint: not available for mouse. gnomAD and Open Targets carry constraint for human genes only.

Ready in a moment

10 Orthologs

The same gene in mouse, rat and human

Reading the Alliance, NCBI, Ensembl Compara and RGD.Still reading. A first read of a gene can take a while; this page waits up to 145 seconds for it, and its scripts then bring in this line, or a line saying what did not arrive.

Ready in a moment

11 MicroRNAs

MicroRNAs hosted within 2610524H06Rik

Reading Ensembl and miRBase.Still reading. A first read of a gene can take a while; this page waits up to 110 seconds for it, and its scripts then bring in this line, or a line saying what did not arrive.

Ready in a moment

12 Long non-coding RNAs

Long non-coding RNAs at the 2610524H06Rik locus

Reading Ensembl.Still reading. A first read of a gene can take a while; this page waits up to 110 seconds for it, and its scripts then bring in this line, or a line saying what did not arrive.

Ready in a moment

13 Literature

Papers that mention 2610524H06Rik

Reading Europe PMC.Still reading. A first read of a gene can take a while; this page waits up to 55 seconds for it, and its scripts then bring in this line, or a line saying what did not arrive.

Ready in a moment

14 Silencing this gene

From 2610524H06Rik to a sequence that silences it

The AUMsilence platform designs the sequences against the mouse transcripts on this page. Six decisions are yours before it does. What is written under each is AUM's guidance; the timings and the concentrations are in the usage guide below.

01
Choose the region
A knockdown oligonucleotide can sit in the 5' untranslated region, the coding sequence or the 3' untranslated region, and all three are used. The coding sequence and the 3' untranslated region are the usual first choices for an RNase H design; the 5' end near the start codon suits a steric block. The map above shows where each region sits on the isoforms it draws.
02
Cover the isoforms you mean
An exon every isoform carries silences the whole gene; an exon only some isoforms carry silences those and spares the rest. Decide which you want before a sequence is chosen, and check the reference transcript (MANE Select in human; RefSeq Select and Ensembl canonical in mouse and rat) is the one your cells express.
03
Think across species early
The orthologs panel says whether mouse and rat carry the same gene. Whether one oligonucleotide can serve two species is a sequence question, settled at design by matching the candidate against each transcript, not by the protein identity shown there.
04
Check expression in your model
A transcript that is not expressed in your cells cannot show knockdown. Confirm the gene is expressed in the cell type and condition you will use, from your own data or a reference atlas, before the order. The expression panel above gives GTEx's median per tissue for a human gene; for mouse and rat it says that no atlas is on this page yet.
05
Run the controls
A scramble control of the same chemistry, a positive control against a gene known to knock down in your cells, untreated cells, and a mock condition where a transfection reagent is used. Read knockdown at the RNA level first, then at the protein; the usage guide gives the timing and the concentrations to start from.
06
Pick the product
AUMsilence sdASO needs no transfection reagent and works in the cells that resist one. AUMsilence toASO is the transfection-optimised version of the same design, and AUMsiRNA is the siRNA route. The selection guide compares them.

Order for 2610524H06Rik Bring your own sequence The usage guide Selection guide

For research use only. Not for use in diagnostic or therapeutic procedures.

Gene Mouse Mus musculus

2610524H06Rik

Reading the record for 2610524H06Rik from NCBI Gene and Ensembl.Still reading. A first read of a gene can take a while; this page waits up to 115 seconds for it, and its scripts then bring in the page, or a line saying what did not arrive.

The full name, the identifiers, the location and the notes from the sources arrive with the record. Nothing is filled in ahead of it.

Order door

The door to order for 2610524H06Rik opens with the record, which decides which product it carries. The order page itself is open now.

Bring your own sequence

For research use only. Not for use in diagnostic or therapeutic procedures.

This page is still reading the record. Its scripts replace this shell with the record when it arrives; with scripts off, it stays at this shell however long you wait.

01 Summary and function

What 2610524H06Rik does

Waiting for the record before reading NCBI Gene and UniProt.

02 Transcripts and isoforms

The RNA a design targets

Waiting for the record before reading NCBI Datasets and Ensembl.

03 Expression by tissue

Where 2610524H06Rik is expressed

Waiting for the record before reading GTEx and the Human Protein Atlas.

04 Protein

The protein 2610524H06Rik encodes

Waiting for the record before reading UniProt, InterPro, AlphaFold DB and PDBe.

05 Interactions

Proteins STRING associates with 2610524H06Rik

Waiting for the record before reading STRING.

06 Pathways

Where 2610524H06Rik acts, as Reactome curates it

Waiting for the record before reading UniProt and Reactome.

07 Disease associations

Diseases linked to 2610524H06Rik

Waiting for the record before reading Open Targets and ClinGen.

08 Variants

Classified variants of 2610524H06Rik

Waiting for the record before reading ClinVar.

09 Constraint

How much variation 2610524H06Rik tolerates

Waiting for the record before reading gnomAD and Open Targets.

10 Orthologs

The same gene in mouse, rat and human

Waiting for the record before reading the Alliance, NCBI, Ensembl Compara and RGD.

11 MicroRNAs

MicroRNAs hosted within 2610524H06Rik

Waiting for the record before reading Ensembl and miRBase.

12 Long non-coding RNAs

Long non-coding RNAs at the 2610524H06Rik locus

Waiting for the record before reading Ensembl.

13 Literature

Papers that mention 2610524H06Rik

Waiting for the record before reading Europe PMC.

Accession	Name	Biotype	Labels	Exons	Spliced length	Protein	Sequence
ENSMUST00000100850.6	Gm57857-202	protein coding	Ensembl canonical	2	420 nt	139 aaENSMUSP00000098411.5	Ready in a moment
ENSMUST00000456457.1	Gm57857-206	protein coding	none	2	6,695 nt	62 aaENSMUSP00000234820.1	Ready in a moment
ENSMUST00000456458.1	Gm57857-207	nonsense mediated decay	none	3	3,533 nt	55 aaENSMUSP00000234821.1	Ready in a moment
ENSMUST00000456461.1	Gm57857-210	protein coding	none	2	1,935 nt	59 aaENSMUSP00000234824.1	Ready in a moment
ENSMUST00000456459.1	Gm57857-208	protein coding	none	3	1,587 nt	132 aaENSMUSP00000234822.1	Ready in a moment
ENSMUST00000112160.4	Gm57857-203	protein coding	none	2	1,333 nt	72 aaENSMUSP00000107786.4	Ready in a moment
ENSMUST00000582931.1	Gm57857-211	protein coding	none	2	1,172 nt	55 aaENSMUSP00000361296.1	Ready in a moment
ENSMUST00000582932.1	Gm57857-212	protein coding	none	3	1,015 nt	60 aaENSMUSP00000361297.1	Ready in a moment
ENSMUST00000456460.1	Gm57857-209	protein coding	none	2	591 nt	73 aaENSMUSP00000234823.1	Ready in a moment
ENSMUST00000140374.3	Gm57857-204	protein coding	none	2	488 nt	72 aaENSMUSP00000116625.2	Ready in a moment
ENSMUST00000234046.2	Gm57857-205	protein coding cds not defined	none	2	947 nt	none	Ready in a moment
ENSMUST00000061251.6	Gm57857-201	protein coding cds not defined	none	2	579 nt	none	Ready in a moment

2610524H06Rik

What 2610524H06Rik does

The RNA a design targets

Where 2610524H06Rik is expressed

The protein 2610524H06Rik encodes

Proteins STRING associates with 2610524H06Rik

Where 2610524H06Rik acts, as Reactome curates it

Diseases linked to 2610524H06Rik

Classified variants of 2610524H06Rik

How much variation 2610524H06Rik tolerates

The same gene in mouse, rat and human

MicroRNAs hosted within 2610524H06Rik

Long non-coding RNAs at the 2610524H06Rik locus

Papers that mention 2610524H06Rik

From 2610524H06Rik to a sequence that silences it

Choose the region

Cover the isoforms you mean

Think across species early

Check expression in your model

Run the controls

Pick the product

2610524H06Rik

What 2610524H06Rik does

The RNA a design targets

Where 2610524H06Rik is expressed

The protein 2610524H06Rik encodes

Proteins STRING associates with 2610524H06Rik

Where 2610524H06Rik acts, as Reactome curates it

Diseases linked to 2610524H06Rik

Classified variants of 2610524H06Rik

How much variation 2610524H06Rik tolerates

The same gene in mouse, rat and human

MicroRNAs hosted within 2610524H06Rik

Long non-coding RNAs at the 2610524H06Rik locus

Papers that mention 2610524H06Rik

2610524H06Rik

What 2610524H06Rik does

Gene summary

Protein function

The RNA a design targets

RefSeq 1 transcript

A window on one transcript

Ensembl 12 transcripts

A window on one transcript

Where 2610524H06Rik is expressed

The protein 2610524H06Rik encodes

Proteins STRING associates with 2610524H06Rik

Where 2610524H06Rik acts, as Reactome curates it

Diseases linked to 2610524H06Rik

Classified variants of 2610524H06Rik

How much variation 2610524H06Rik tolerates

The same gene in mouse, rat and human

MicroRNAs hosted within 2610524H06Rik

Long non-coding RNAs at the 2610524H06Rik locus

Papers that mention 2610524H06Rik

From 2610524H06Rik to a sequence that silences it

Choose the region

Cover the isoforms you mean

Think across species early

Check expression in your model

Run the controls

Pick the product

Gene summary

Protein function

RefSeq 1 transcript

A window on one transcript

Ensembl 12 transcripts

A window on one transcript