Gene Mouse Mus musculus

Gm50092

predicted gene, 50092

protein coding

HumanMouse Gm50092Rat

Reading the ortholog votes for human and rat.

HGNC and MANE Select: not available for mouse. HGNC names human genes; MGI is the authority here, and MANE Select is defined for human transcripts only.

Location: Cytogenetic band 7 A3NCBI: no location on GRCm39 in the current annotation.Ensembl: no location was read.Coordinates are one-based with both ends included, as each source reports them.

Gene identity, from NCBI Datasets · NCBI Datasets 18.38.0 · read 2026-10-07 ET · MGI:6275428Data from NCBI, provided as is; NCBI's policies and disclaimers apply.

Notes from the sources

Ensembl did not answer (upstream error).
NCBI Gene has no annotation on GRCm39 for this gene
Ensembl did not answer (upstream error); the Ensembl location and release are missing

Silence this gene

The order page opens with Gm50092 and mouse filled in. The sequences are designed against the transcripts below; the price is on that page.

Order for Gm50092

sdASO, toASO or siRNA

Bring your own sequence Transcripts

For research use only. Not for use in diagnostic or therapeutic procedures.

Summary
Transcripts
Expression
Protein
Interactions
Pathways
Disease
Variants
Constraint
Orthologs
MicroRNAs
Long non-coding RNAs
Literature
Silencing this gene

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01 Summary and function

What Gm50092 does

NCBI Gene carries no curated summary for this gene. UniProt has 0 reviewed entries named Gm50092 in mouse.

NCBI Gene summary

Ready in a moment

02 Transcripts and isoforms

The RNA a design targets

NCBI Datasets is not answering, so the transcripts could not be shown. Try again later. Reference 9cde4e3c-918.

Ready in a moment

03 Expression by tissue

Where Gm50092 is expressed

Expression by tissue: not available for mouse. GTEx holds human tissues only, and the Human Protein Atlas is keyed on human genes.

Ready in a moment

04 Protein

The protein Gm50092 encodes

UniProt did not give one reviewed entry for Gm50092 in mouse, so InterPro, AlphaFold DB and PDBe were not asked and no protein entry is shown.

UniProt

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05 Interactions

Proteins STRING associates with Gm50092

Reading STRING.Still reading. A first read of a gene can take a while; this page waits up to 50 seconds for it, and its scripts then bring in this line, or a line saying what did not arrive.

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06 Pathways

Where Gm50092 acts, as Reactome curates it

UniProt did not give one reviewed entry for Gm50092 in mouse, so Reactome was not asked and no pathway list is shown.

UniProt

Ready in a moment

07 Disease associations

Diseases linked to Gm50092

Disease associations: not available for mouse. Open Targets and ClinGen curate human genes only. The human ortholog's page carries the associations.

Ready in a moment

08 Variants

Classified variants of Gm50092

Clinical variants: not available for mouse. ClinVar holds human variants only.

Ready in a moment

09 Constraint

How much variation Gm50092 tolerates

Constraint: not available for mouse. gnomAD and Open Targets carry constraint for human genes only.

Ready in a moment

10 Orthologs

The same gene in mouse, rat and human

Human: no ortholog named by the 2 votes that answered; rat: no ortholog named by the 2 votes that answered. RGD is not answering, so the ortholog list could not be shown. Try again later. Reference 519ac682-679.

Alliance · NCBI

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11 MicroRNAs

MicroRNAs hosted within Gm50092

Ensembl is not answering, so the non-coding annotation could not be shown. Try again later. Reference 9cde4e3c-918.

Ready in a moment

12 Long non-coding RNAs

Long non-coding RNAs at the Gm50092 locus

Ensembl is not answering, so the non-coding annotation could not be shown. Try again later. Reference 9cde4e3c-918.

Ready in a moment

13 Literature

Papers that mention Gm50092

Reading Europe PMC.Still reading. A first read of a gene can take a while; this page waits up to 55 seconds for it, and its scripts then bring in this line, or a line saying what did not arrive.

Ready in a moment

14 Silencing this gene

From Gm50092 to a sequence that silences it

The AUMsilence platform designs the sequences against the mouse transcripts on this page. Six decisions are yours before it does. What is written under each is AUM's guidance; the timings and the concentrations are in the usage guide below.

01
Choose the region
A knockdown oligonucleotide can sit in the 5' untranslated region, the coding sequence or the 3' untranslated region, and all three are used. The coding sequence and the 3' untranslated region are the usual first choices for an RNase H design; the 5' end near the start codon suits a steric block. The map above shows where each region sits on the isoforms it draws.
02
Cover the isoforms you mean
An exon every isoform carries silences the whole gene; an exon only some isoforms carry silences those and spares the rest. Decide which you want before a sequence is chosen, and check the reference transcript (MANE Select in human; RefSeq Select and Ensembl canonical in mouse and rat) is the one your cells express.
03
Think across species early
The orthologs panel says whether mouse and rat carry the same gene. Whether one oligonucleotide can serve two species is a sequence question, settled at design by matching the candidate against each transcript, not by the protein identity shown there.
04
Check expression in your model
A transcript that is not expressed in your cells cannot show knockdown. Confirm the gene is expressed in the cell type and condition you will use, from your own data or a reference atlas, before the order. The expression panel above gives GTEx's median per tissue for a human gene; for mouse and rat it says that no atlas is on this page yet.
05
Run the controls
A scramble control of the same chemistry, a positive control against a gene known to knock down in your cells, untreated cells, and a mock condition where a transfection reagent is used. Read knockdown at the RNA level first, then at the protein; the usage guide gives the timing and the concentrations to start from.
06
Pick the product
AUMsilence sdASO needs no transfection reagent and works in the cells that resist one. AUMsilence toASO is the transfection-optimised version of the same design, and AUMsiRNA is the siRNA route. The selection guide compares them.

Order for Gm50092 Bring your own sequence The usage guide Selection guide

For research use only. Not for use in diagnostic or therapeutic procedures.

Gene Mouse Mus musculus

Gm50092

Reading the record for Gm50092 from NCBI Gene and Ensembl.Still reading. A first read of a gene can take a while; this page waits up to 115 seconds for it, and its scripts then bring in the page, or a line saying what did not arrive.

The full name, the identifiers, the location and the notes from the sources arrive with the record. Nothing is filled in ahead of it.

Order door

The door to order for Gm50092 opens with the record, which decides which product it carries. The order page itself is open now.

Bring your own sequence

For research use only. Not for use in diagnostic or therapeutic procedures.

This page is still reading the record. Its scripts replace this shell with the record when it arrives; with scripts off, it stays at this shell however long you wait.

01 Summary and function

What Gm50092 does

Waiting for the record before reading NCBI Gene and UniProt.

02 Transcripts and isoforms

The RNA a design targets

Waiting for the record before reading NCBI Datasets and Ensembl.

03 Expression by tissue

Where Gm50092 is expressed

Waiting for the record before reading GTEx and the Human Protein Atlas.

04 Protein

The protein Gm50092 encodes

Waiting for the record before reading UniProt, InterPro, AlphaFold DB and PDBe.

05 Interactions

Proteins STRING associates with Gm50092

Waiting for the record before reading STRING.

06 Pathways

Where Gm50092 acts, as Reactome curates it

Waiting for the record before reading UniProt and Reactome.

07 Disease associations

Diseases linked to Gm50092

Waiting for the record before reading Open Targets and ClinGen.

08 Variants

Classified variants of Gm50092

Waiting for the record before reading ClinVar.

09 Constraint

How much variation Gm50092 tolerates

Waiting for the record before reading gnomAD and Open Targets.

10 Orthologs

The same gene in mouse, rat and human

Waiting for the record before reading the Alliance, NCBI, Ensembl Compara and RGD.

11 MicroRNAs

MicroRNAs hosted within Gm50092

Waiting for the record before reading Ensembl and miRBase.

12 Long non-coding RNAs

Long non-coding RNAs at the Gm50092 locus

Waiting for the record before reading Ensembl.

13 Literature

Papers that mention Gm50092

Waiting for the record before reading Europe PMC.

Gm50092

predicted gene, 50092

protein coding

Human: no ortholog is named for this gene: the Alliance and NCBI answered and named none; Ensembl Compara did not answer (upstream error, reference 9cde4e3c-918).
Rat: no ortholog is named for this gene: the Alliance and NCBI answered and named none; Ensembl Compara did not answer (upstream error, reference 9cde4e3c-918).

HumanMouse Gm50092Rat

Reading the ortholog votes for human and rat.

HGNC and MANE Select: not available for mouse. HGNC names human genes; MGI is the authority here, and MANE Select is defined for human transcripts only.

Location

Cytogenetic band 7 A3NCBI: no location on GRCm39 in the current annotation.Ensembl: no location was read.Coordinates are one-based with both ends included, as each source reports them.

Gene identity, from NCBI Datasets · NCBI Datasets 18.38.0 · read 2026-10-07 ET · MGI:6275428Data from NCBI, provided as is; NCBI's policies and disclaimers apply.

Notes from the sources

Ensembl did not answer (upstream error).
NCBI Gene has no annotation on GRCm39 for this gene
Ensembl did not answer (upstream error); the Ensembl location and release are missing

From Gm50092 to a sequence that silences it

Choose the region

A knockdown oligonucleotide can sit in the 5' untranslated region, the coding sequence or the 3' untranslated region, and all three are used. The coding sequence and the 3' untranslated region are the usual first choices for an RNase H design; the 5' end near the start codon suits a steric block. The map above shows where each region sits on the isoforms it draws.

Cover the isoforms you mean

An exon every isoform carries silences the whole gene; an exon only some isoforms carry silences those and spares the rest. Decide which you want before a sequence is chosen, and check the reference transcript (MANE Select in human; RefSeq Select and Ensembl canonical in mouse and rat) is the one your cells express.

Think across species early

The orthologs panel says whether mouse and rat carry the same gene. Whether one oligonucleotide can serve two species is a sequence question, settled at design by matching the candidate against each transcript, not by the protein identity shown there.

Check expression in your model

A transcript that is not expressed in your cells cannot show knockdown. Confirm the gene is expressed in the cell type and condition you will use, from your own data or a reference atlas, before the order. The expression panel above gives GTEx's median per tissue for a human gene; for mouse and rat it says that no atlas is on this page yet.

Run the controls

A scramble control of the same chemistry, a positive control against a gene known to knock down in your cells, untreated cells, and a mock condition where a transfection reagent is used. Read knockdown at the RNA level first, then at the protein; the usage guide gives the timing and the concentrations to start from.

Pick the product

AUMsilence sdASO needs no transfection reagent and works in the cells that resist one. AUMsilence toASO is the transfection-optimised version of the same design, and AUMsiRNA is the siRNA route. The selection guide compares them.

For research use only. Not for use in diagnostic or therapeutic procedures.

Gm50092

What Gm50092 does

The RNA a design targets

Where Gm50092 is expressed

The protein Gm50092 encodes

Proteins STRING associates with Gm50092

Where Gm50092 acts, as Reactome curates it

Diseases linked to Gm50092

Classified variants of Gm50092

How much variation Gm50092 tolerates

The same gene in mouse, rat and human

MicroRNAs hosted within Gm50092

Long non-coding RNAs at the Gm50092 locus

Papers that mention Gm50092

From Gm50092 to a sequence that silences it

Choose the region

Cover the isoforms you mean

Think across species early

Check expression in your model

Run the controls

Pick the product

Gm50092

What Gm50092 does

The RNA a design targets

Where Gm50092 is expressed

The protein Gm50092 encodes

Proteins STRING associates with Gm50092

Where Gm50092 acts, as Reactome curates it

Diseases linked to Gm50092

Classified variants of Gm50092

How much variation Gm50092 tolerates

The same gene in mouse, rat and human

MicroRNAs hosted within Gm50092

Long non-coding RNAs at the Gm50092 locus

Papers that mention Gm50092

Gm50092

What Gm50092 does

Gene summary

Protein function

The RNA a design targets

Where Gm50092 is expressed

The protein Gm50092 encodes

Proteins STRING associates with Gm50092

Where Gm50092 acts, as Reactome curates it

Diseases linked to Gm50092

Classified variants of Gm50092

How much variation Gm50092 tolerates

The same gene in mouse, rat and human

MicroRNAs hosted within Gm50092

Long non-coding RNAs at the Gm50092 locus

Papers that mention Gm50092

From Gm50092 to a sequence that silences it

Choose the region

Cover the isoforms you mean

Think across species early

Check expression in your model

Run the controls

Pick the product

Gene summary

Protein function