Gene Mouse Mus musculus

Tmem242

transmembrane protein 242

protein coding

HGNC and MANE Select: not available for mouse. HGNC names human genes; MGI is the authority here, and MANE Select is defined for human transcripts only.

Location: Cytogenetic band 17 A1NCBI: 17:5,461,139-5,490,535 on the minus strand, GRCm39 (GCF_000001635.27), sequence NC_000083.7, annotation GCF_000001635.27-RS_2024_02 of 2024-02-01Ensembl: 17:5,460,524-5,490,535 on the minus strand, GRCm39 (GCA_000001635.9), release 116Coordinates are one-based with both ends included, as each source reports them.
Also known as: 1110008A10Rik, 2310046K16Rik, 5730437N04Rik

Gene identity, from NCBI Datasets · NCBI Datasets 18.38.0 · read 2026-10-05 ET · MGI:1917794Data from NCBI, provided as is; NCBI's policies and disclaimers apply.

Silence this gene

The order page opens with Tmem242 and mouse filled in. The sequences are designed against the transcripts below; the price is on that page.

Order for Tmem242

sdASO, toASO or siRNA

Bring your own sequence Transcripts

For research use only. Not for use in diagnostic or therapeutic procedures.

Summary
Transcripts
Expression
Protein
Interactions
Pathways
Disease
Variants
Constraint
Orthologs
MicroRNAs
Long non-coding RNAs
Literature
Silencing this gene

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Ready in a moment

01 Summary and function

What Tmem242 does

Ready in a moment

02 Transcripts and isoforms

The RNA a design targets

Ready in a moment

03 Expression by tissue

Where Tmem242 is expressed

Ready in a moment

14 Silencing this gene

From Tmem242 to a sequence that silences it

The AUMsilence platform designs the sequences against the mouse transcripts on this page. Six decisions are yours before it does. What is written under each is AUM's guidance; the timings and the concentrations are in the usage guide below.

01
Choose the region
A knockdown oligonucleotide can sit in the 5' untranslated region, the coding sequence or the 3' untranslated region, and all three are used. The coding sequence and the 3' untranslated region are the usual first choices for an RNase H design; the 5' end near the start codon suits a steric block. The map above shows where each region sits on the isoforms it draws.
02
Cover the isoforms you mean
An exon every isoform carries silences the whole gene; an exon only some isoforms carry silences those and spares the rest. Decide which you want before a sequence is chosen, and check the reference transcript (MANE Select in human; RefSeq Select and Ensembl canonical in mouse and rat) is the one your cells express.
03
Think across species early
The orthologs panel says whether mouse and rat carry the same gene. Whether one oligonucleotide can serve two species is a sequence question, settled at design by matching the candidate against each transcript, not by the protein identity shown there.
04
Check expression in your model
A transcript that is not expressed in your cells cannot show knockdown. Confirm the gene is expressed in the cell type and condition you will use, from your own data or a reference atlas, before the order. The expression panel above gives GTEx's median per tissue for a human gene; for mouse and rat it says that no atlas is on this page yet.

Gene Mouse Mus musculus

Tmem242

Reading the record for Tmem242 from NCBI Gene and Ensembl.Still reading. A first read of a gene can take a while; this page waits up to 115 seconds for it, and its scripts then bring in the page, or a line saying what did not arrive.

The full name, the identifiers, the location and the notes from the sources arrive with the record. Nothing is filled in ahead of it.

Order door

The door to order for Tmem242 opens with the record, which decides which product it carries. The order page itself is open now.

Bring your own sequence

For research use only. Not for use in diagnostic or therapeutic procedures.

This page is still reading the record. Its scripts replace this shell with the record when it arrives; with scripts off, it stays at this shell however long you wait.

01 Summary and function

What Tmem242 does

Waiting for the record before reading NCBI Gene and UniProt.

02 Transcripts and isoforms

The RNA a design targets

Waiting for the record before reading NCBI Datasets and Ensembl.

03 Expression by tissue

Where Tmem242 is expressed

Waiting for the record before reading GTEx and the Human Protein Atlas.

04 Protein

The protein Tmem242 encodes

Waiting for the record before reading UniProt, InterPro, AlphaFold DB and PDBe.

05 Interactions

Proteins STRING associates with Tmem242

Waiting for the record before reading STRING.

06 Pathways

Where Tmem242 acts, as Reactome curates it

Waiting for the record before reading UniProt and Reactome.

07 Disease associations

Diseases linked to Tmem242

Waiting for the record before reading Open Targets and ClinGen.

08 Variants

Classified variants of Tmem242

Waiting for the record before reading ClinVar.

09 Constraint

How much variation Tmem242 tolerates

Waiting for the record before reading gnomAD and Open Targets.

10 Orthologs

The same gene in mouse, rat and human

Waiting for the record before reading the Alliance, NCBI, Ensembl Compara and RGD.

11 MicroRNAs

MicroRNAs hosted within Tmem242

Waiting for the record before reading Ensembl and miRBase.

12 Long non-coding RNAs

Long non-coding RNAs at the Tmem242 locus

Waiting for the record before reading Ensembl.

13 Literature

Papers that mention Tmem242

Waiting for the record before reading Europe PMC.

Tmem242

transmembrane protein 242

protein coding

HGNC and MANE Select: not available for mouse. HGNC names human genes; MGI is the authority here, and MANE Select is defined for human transcripts only.

Location

Cytogenetic band 17 A1NCBI: 17:5,461,139-5,490,535 on the minus strand, GRCm39 (GCF_000001635.27), sequence NC_000083.7, annotation GCF_000001635.27-RS_2024_02 of 2024-02-01Ensembl: 17:5,460,524-5,490,535 on the minus strand, GRCm39 (GCA_000001635.9), release 116Coordinates are one-based with both ends included, as each source reports them.

Also known as

1110008A10Rik, 2310046K16Rik, 5730437N04Rik

Gene identity, from NCBI Datasets · NCBI Datasets 18.38.0 · read 2026-10-05 ET · MGI:1917794Data from NCBI, provided as is; NCBI's policies and disclaimers apply.

RefSeq transcripts of this gene
Accession	Name	Biotype	Labels	Exons	Spliced length	Protein	Sequence
NM_027457.4matches ENSMUST00000005053.15	none given	protein coding	RefSeq Select	4	971 nt	140 aaNP_081733.3	Ready in a moment

Accession

Name

Biotype

Labels

Exons

Spliced length

Protein

Sequence

NM_027457.4matches ENSMUST00000005053.15

none given

protein coding

RefSeq Select

971 nt

140 aaNP_081733.3

Ready in a moment

From Tmem242 to a sequence that silences it

Choose the region

A knockdown oligonucleotide can sit in the 5' untranslated region, the coding sequence or the 3' untranslated region, and all three are used. The coding sequence and the 3' untranslated region are the usual first choices for an RNase H design; the 5' end near the start codon suits a steric block. The map above shows where each region sits on the isoforms it draws.

Cover the isoforms you mean

An exon every isoform carries silences the whole gene; an exon only some isoforms carry silences those and spares the rest. Decide which you want before a sequence is chosen, and check the reference transcript (MANE Select in human; RefSeq Select and Ensembl canonical in mouse and rat) is the one your cells express.

Think across species early

The orthologs panel says whether mouse and rat carry the same gene. Whether one oligonucleotide can serve two species is a sequence question, settled at design by matching the candidate against each transcript, not by the protein identity shown there.

Check expression in your model

A transcript that is not expressed in your cells cannot show knockdown. Confirm the gene is expressed in the cell type and condition you will use, from your own data or a reference atlas, before the order. The expression panel above gives GTEx's median per tissue for a human gene; for mouse and rat it says that no atlas is on this page yet.

RefSeq transcripts of this gene
Accession	Name	Biotype	Labels	Exons	Spliced length	Protein	Sequence
NM_027457.4matches ENSMUST00000005053.15	none given	protein coding	RefSeq Select	4	971 nt	140 aaNP_081733.3	Ready in a moment

Accession

Name

Biotype

Labels

Exons

Spliced length

Protein

Sequence

NM_027457.4matches ENSMUST00000005053.15

none given

protein coding

RefSeq Select

971 nt

140 aaNP_081733.3

Ready in a moment

Accession	Name	Biotype	Labels	Exons	Spliced length	Protein	Sequence
ENSMUST00000005053.15	Tmem242-201	protein coding	Ensembl canonical	4	967 nt	140 aaENSMUSP00000005053.8	Ready in a moment
ENSMUST00000466908.1	Tmem242-210	protein coding	none	2	2,502 nt	70 aaENSMUSP00000245271.1	Ready in a moment
ENSMUST00000466902.1	Tmem242-204	nonsense mediated decay	none	5	1,796 nt	113 aaENSMUSP00000245265.1	Ready in a moment
ENSMUST00000466903.1	Tmem242-205	nonsense mediated decay	none	5	1,737 nt	125 aaENSMUSP00000245266.1	Ready in a moment
ENSMUST00000552419.1	Tmem242-211	nonsense mediated decay	none	5	1,272 nt	114 aaENSMUSP00000330782.1	Ready in a moment
ENSMUST00000552420.1	Tmem242-212	nonsense mediated decay	none	6	1,188 nt	114 aaENSMUSP00000330783.1	Ready in a moment
ENSMUST00000466906.1	Tmem242-208	nonsense mediated decay	none	4	1,066 nt	75 aaENSMUSP00000245269.1	Ready in a moment
ENSMUST00000466904.1	Tmem242-206	protein coding	none	5	1,036 nt	114 aaENSMUSP00000245267.1	Ready in a moment
ENSMUST00000466905.1	Tmem242-207	protein coding	none	4	965 nt	113 aaENSMUSP00000245268.1	Ready in a moment
ENSMUST00000466907.1	Tmem242-209	protein coding	none	3	866 nt	80 aaENSMUSP00000245270.1	Ready in a moment
ENSMUST00000552421.1	Tmem242-213	protein coding	none	4	836 nt	113 aaENSMUSP00000330784.1	Ready in a moment
ENSMUST00000572825.1	Tmem242-214	protein coding	none	3	829 nt	94 aaENSMUSP00000351188.1	Ready in a moment
ENSMUST00000188282.8	Tmem242-203	protein coding	none	4	823 nt	118 aaENSMUSP00000139629.2	Ready in a moment
ENSMUST00000185896.3	Tmem242-202	protein coding	none	3	784 nt	139 aaENSMUSP00000139712.2	Ready in a moment

Tmem242

What Tmem242 does

The RNA a design targets

Where Tmem242 is expressed

From Tmem242 to a sequence that silences it

Choose the region

Cover the isoforms you mean

Think across species early

Check expression in your model

Tmem242

What Tmem242 does

The RNA a design targets

Where Tmem242 is expressed

The protein Tmem242 encodes

Proteins STRING associates with Tmem242

Where Tmem242 acts, as Reactome curates it

Diseases linked to Tmem242

Classified variants of Tmem242

How much variation Tmem242 tolerates

The same gene in mouse, rat and human

MicroRNAs hosted within Tmem242

Long non-coding RNAs at the Tmem242 locus

Papers that mention Tmem242

Tmem242

What Tmem242 does

Gene summary

Protein function

The RNA a design targets

RefSeq 1 transcript

A window on one transcript

Ensembl 14 transcripts

A window on one transcript

Where Tmem242 is expressed

From Tmem242 to a sequence that silences it

Choose the region

Cover the isoforms you mean

Think across species early

Check expression in your model

The protein Tmem242 encodes

Proteins STRING associates with Tmem242

Where Tmem242 acts, as Reactome curates it

Diseases linked to Tmem242

Classified variants of Tmem242

How much variation Tmem242 tolerates

The same gene in mouse, rat and human

MicroRNAs hosted within Tmem242

Long non-coding RNAs at the Tmem242 locus

Papers that mention Tmem242

Run the controls

Pick the product

Gene summary

Protein function

RefSeq 1 transcript

A window on one transcript

Ensembl 14 transcripts

A window on one transcript