Gene Rat Rattus norvegicus

Pcyox1

prenylcysteine oxidase 1

protein coding

HGNC and MANE Select: not available for rat. HGNC names human genes; RGD is the authority here, and MANE Select is defined for human transcripts only.

Location: Cytogenetic band 4q34NCBI: 4:120,388,061-120,400,382 on the minus strand, GRCr8 (GCF_036323735.1), sequence NC_086022.1, annotation GCF_036323735.1-RS_2026_08 of 2026-08-17Ensembl: 4:120,388,180-120,400,382 on the minus strand, GRCr8 (GCA_036323735.1), release 116Coordinates are one-based with both ends included, as each source reports them.
Also known as: Clp55

Gene identity, from NCBI Datasets · NCBI Datasets 18.38.0 · read 2026-10-04 ET · RGD:628652Data from NCBI, provided as is; NCBI's policies and disclaimers apply.

Silence this gene

The order page opens with Pcyox1 and rat filled in. The sequences are designed against the transcripts below; the price is on that page.

Order for Pcyox1

sdASO, toASO or siRNA

Bring your own sequence Transcripts

For research use only. Not for use in diagnostic or therapeutic procedures.

Summary
Transcripts
Expression
Protein
Interactions
Pathways
Disease
Variants
Constraint
Orthologs
MicroRNAs
Long non-coding RNAs
Literature
Silencing this gene

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Ready in a moment

01 Summary and function

What Pcyox1 does

Ready in a moment

02 Transcripts and isoforms

The RNA a design targets

Ready in a moment

03 Expression by tissue

Where Pcyox1 is expressed

Ready in a moment

14 Silencing this gene

From Pcyox1 to a sequence that silences it

The AUMsilence platform designs the sequences against the rat transcripts on this page. Six decisions are yours before it does. What is written under each is AUM's guidance; the timings and the concentrations are in the usage guide below.

01
Choose the region
A knockdown oligonucleotide can sit in the 5' untranslated region, the coding sequence or the 3' untranslated region, and all three are used. The coding sequence and the 3' untranslated region are the usual first choices for an RNase H design; the 5' end near the start codon suits a steric block. The map above shows where each region sits on the isoforms it draws.
02
Cover the isoforms you mean
An exon every isoform carries silences the whole gene; an exon only some isoforms carry silences those and spares the rest. Decide which you want before a sequence is chosen, and check the reference transcript (MANE Select in human; RefSeq Select and Ensembl canonical in mouse and rat) is the one your cells express.
03
Think across species early
The orthologs panel says whether mouse and rat carry the same gene. Whether one oligonucleotide can serve two species is a sequence question, settled at design by matching the candidate against each transcript, not by the protein identity shown there.
04
Check expression in your model
A transcript that is not expressed in your cells cannot show knockdown. Confirm the gene is expressed in the cell type and condition you will use, from your own data or a reference atlas, before the order. The expression panel above gives GTEx's median per tissue for a human gene; for mouse and rat it says that no atlas is on this page yet.

Gene Rat Rattus norvegicus

Pcyox1

Reading the record for Pcyox1 from NCBI Gene and Ensembl.Still reading. A first read of a gene can take a while; this page waits up to 115 seconds for it, and its scripts then bring in the page, or a line saying what did not arrive.

The full name, the identifiers, the location and the notes from the sources arrive with the record. Nothing is filled in ahead of it.

Order door

The door to order for Pcyox1 opens with the record, which decides which product it carries. The order page itself is open now.

Bring your own sequence

For research use only. Not for use in diagnostic or therapeutic procedures.

This page is still reading the record. Its scripts replace this shell with the record when it arrives; with scripts off, it stays at this shell however long you wait.

01 Summary and function

What Pcyox1 does

Waiting for the record before reading NCBI Gene and UniProt.

02 Transcripts and isoforms

The RNA a design targets

Waiting for the record before reading NCBI Datasets and Ensembl.

03 Expression by tissue

Where Pcyox1 is expressed

Waiting for the record before reading GTEx and the Human Protein Atlas.

04 Protein

The protein Pcyox1 encodes

Waiting for the record before reading UniProt, InterPro, AlphaFold DB and PDBe.

05 Interactions

Proteins STRING associates with Pcyox1

Waiting for the record before reading STRING.

06 Pathways

Where Pcyox1 acts, as Reactome curates it

Waiting for the record before reading UniProt and Reactome.

07 Disease associations

Diseases linked to Pcyox1

Waiting for the record before reading Open Targets and ClinGen.

08 Variants

Classified variants of Pcyox1

Waiting for the record before reading ClinVar.

09 Constraint

How much variation Pcyox1 tolerates

Waiting for the record before reading gnomAD and Open Targets.

10 Orthologs

The same gene in mouse, rat and human

Waiting for the record before reading the Alliance, NCBI, Ensembl Compara and RGD.

11 MicroRNAs

MicroRNAs hosted within Pcyox1

Waiting for the record before reading Ensembl and miRBase.

12 Long non-coding RNAs

Long non-coding RNAs at the Pcyox1 locus

Waiting for the record before reading Ensembl.

13 Literature

Papers that mention Pcyox1

Waiting for the record before reading Europe PMC.

Pcyox1

prenylcysteine oxidase 1

protein coding

HGNC and MANE Select: not available for rat. HGNC names human genes; RGD is the authority here, and MANE Select is defined for human transcripts only.

Location

Cytogenetic band 4q34NCBI: 4:120,388,061-120,400,382 on the minus strand, GRCr8 (GCF_036323735.1), sequence NC_086022.1, annotation GCF_036323735.1-RS_2026_08 of 2026-08-17Ensembl: 4:120,388,180-120,400,382 on the minus strand, GRCr8 (GCA_036323735.1), release 116Coordinates are one-based with both ends included, as each source reports them.

Also known as

Clp55

Gene identity, from NCBI Datasets · NCBI Datasets 18.38.0 · read 2026-10-04 ET · RGD:628652Data from NCBI, provided as is; NCBI's policies and disclaimers apply.

RefSeq transcripts of this gene
Accession	Name	Biotype	Labels	Exons	Spliced length	Protein	Sequence
NM_145085.2matches ENSRNOT00000022532.8	none given	protein coding	RefSeq Select	6	2,292 ntexons sum to 2,233 nt; the record carries 59 nt beyond them	504 aaNP_659553.1	Ready in a moment
XM_087613815.1matches ENSRNOT00000097224.2	transcript variant X1	protein coding model	none	6	3,801 nt	491 aaXP_087469941.1	Ready in a moment

Accession

Name

Biotype

Labels

Exons

Spliced length

Protein

Sequence

NM_145085.2matches ENSRNOT00000022532.8

none given

protein coding

RefSeq Select

2,292 ntexons sum to 2,233 nt; the record carries 59 nt beyond them

504 aaNP_659553.1

Ready in a moment

XM_087613815.1matches ENSRNOT00000097224.2

transcript variant X1

protein coding model

none

3,801 nt

491 aaXP_087469941.1

Ready in a moment

From Pcyox1 to a sequence that silences it

Choose the region

A knockdown oligonucleotide can sit in the 5' untranslated region, the coding sequence or the 3' untranslated region, and all three are used. The coding sequence and the 3' untranslated region are the usual first choices for an RNase H design; the 5' end near the start codon suits a steric block. The map above shows where each region sits on the isoforms it draws.

Cover the isoforms you mean

An exon every isoform carries silences the whole gene; an exon only some isoforms carry silences those and spares the rest. Decide which you want before a sequence is chosen, and check the reference transcript (MANE Select in human; RefSeq Select and Ensembl canonical in mouse and rat) is the one your cells express.

Think across species early

The orthologs panel says whether mouse and rat carry the same gene. Whether one oligonucleotide can serve two species is a sequence question, settled at design by matching the candidate against each transcript, not by the protein identity shown there.

Check expression in your model

A transcript that is not expressed in your cells cannot show knockdown. Confirm the gene is expressed in the cell type and condition you will use, from your own data or a reference atlas, before the order. The expression panel above gives GTEx's median per tissue for a human gene; for mouse and rat it says that no atlas is on this page yet.

RefSeq transcripts of this gene
Accession	Name	Biotype	Labels	Exons	Spliced length	Protein	Sequence
NM_145085.2matches ENSRNOT00000022532.8	none given	protein coding	RefSeq Select	6	2,292 ntexons sum to 2,233 nt; the record carries 59 nt beyond them	504 aaNP_659553.1	Ready in a moment
XM_087613815.1matches ENSRNOT00000097224.2	transcript variant X1	protein coding model	none	6	3,801 nt	491 aaXP_087469941.1	Ready in a moment

Accession

Name

Biotype

Labels

Exons

Spliced length

Protein

Sequence

NM_145085.2matches ENSRNOT00000022532.8

none given

protein coding

RefSeq Select

2,292 ntexons sum to 2,233 nt; the record carries 59 nt beyond them

504 aaNP_659553.1

Ready in a moment

XM_087613815.1matches ENSRNOT00000097224.2

transcript variant X1

protein coding model

none

3,801 nt

491 aaXP_087469941.1

Ready in a moment

Accession	Name	Biotype	Labels	Exons	Spliced length	Protein	Sequence
ENSRNOT00000022532.8	Pcyox1-201	protein coding	Ensembl canonical	6	2,417 nt	511 aaENSRNOP00000022532.5	Ready in a moment
ENSRNOT00000097224.2	Pcyox1-202	protein coding	none	6	2,534 nt	491 aaENSRNOP00000096730.1	Ready in a moment
ENSRNOT00000105157.2	Pcyox1-203	protein coding	none	7	1,414 nt	457 aaENSRNOP00000079738.1	Ready in a moment
ENSRNOT00000105646.2	Pcyox1-204	protein coding	none	4	487 nt	148 aaENSRNOP00000080363.1	Ready in a moment

Pcyox1

What Pcyox1 does

The RNA a design targets

Where Pcyox1 is expressed

From Pcyox1 to a sequence that silences it

Choose the region

Cover the isoforms you mean

Think across species early

Check expression in your model

Pcyox1

What Pcyox1 does

The RNA a design targets

Where Pcyox1 is expressed

The protein Pcyox1 encodes

Proteins STRING associates with Pcyox1

Where Pcyox1 acts, as Reactome curates it

Diseases linked to Pcyox1

Classified variants of Pcyox1

How much variation Pcyox1 tolerates

The same gene in mouse, rat and human

MicroRNAs hosted within Pcyox1

Long non-coding RNAs at the Pcyox1 locus

Papers that mention Pcyox1

Pcyox1

What Pcyox1 does

Gene summary

Protein function

The RNA a design targets

RefSeq 2 transcripts

A window on one transcript

Ensembl 4 transcripts

A window on one transcript

Where Pcyox1 is expressed

From Pcyox1 to a sequence that silences it

Choose the region

Cover the isoforms you mean

Think across species early

Check expression in your model

The protein Pcyox1 encodes

Proteins STRING associates with Pcyox1

Where Pcyox1 acts, as Reactome curates it

Diseases linked to Pcyox1

Classified variants of Pcyox1

How much variation Pcyox1 tolerates

The same gene in mouse, rat and human

MicroRNAs hosted within Pcyox1

Long non-coding RNAs at the Pcyox1 locus

Papers that mention Pcyox1

Run the controls

Pick the product

Gene summary

Protein function

RefSeq 2 transcripts

A window on one transcript

Ensembl 4 transcripts

A window on one transcript