Gene Rat Rattus norvegicus

Ube2v2

ubiquitin conjugating enzyme E2 V2

protein coding

HumanMouseRat Ube2v2

Reading the ortholog votes for human and mouse.

HGNC and MANE Select: not available for rat. HGNC names human genes; RGD is the authority here, and MANE Select is defined for human transcripts only.

Location: Cytogenetic band 11q23NCBI: 11:98,808,681-98,842,583 on the plus strand, GRCr8 (GCF_036323735.1), sequence NC_086029.1, annotation GCF_036323735.1-RS_2026_08 of 2026-08-17Ensembl: 11:98,807,538-98,843,211 on the plus strand, GRCr8 (GCA_036323735.1), release 116Coordinates are one-based with both ends included, as each source reports them.
Also known as: MMS2

Gene identity, from NCBI Datasets · NCBI Datasets 18.37.0 · read 2026-09-25 ET · RGD:727838Data from NCBI, provided as is; NCBI's policies and disclaimers apply.

Silence this gene

The order page opens with Ube2v2 and rat filled in. The sequences are designed against the transcripts below; the price is on that page.

Order for Ube2v2

sdASO, toASO or siRNA, chosen on the next page

Bring your own sequence Transcripts

For research use only. Not for use in diagnostic or therapeutic procedures.

Summary
Transcripts
Expression
Protein
Interactions
Pathways
Disease
Variants

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Ready in a moment

01 Summary and function

What Ube2v2 does

Ready in a moment

02 Transcripts and isoforms

The RNA a design targets

Reading NCBI Datasets and Ensembl.Still reading. A first read of a gene can take a while; this page waits up to 80 seconds for it, and its scripts then bring in this line, or a line saying what did not arrive.

Ready in a moment

14 Silencing this gene

From Ube2v2 to a sequence that silences it

The AUMsilence platform designs the sequences against the rat transcripts on this page. Six decisions are yours before it does. What is written under each is AUM's guidance; the timings and the concentrations are in the usage guide below.

01
Choose the region
A knockdown oligonucleotide can sit in the 5' untranslated region, the coding sequence or the 3' untranslated region, and all three are used. The coding sequence and the 3' untranslated region are the usual first choices for an RNase H design; the 5' end near the start codon suits a steric block. The map above shows where each region sits on the isoforms it draws.
02
Cover the isoforms you mean
An exon every isoform carries silences the whole gene; an exon only some isoforms carry silences those and spares the rest. Decide which you want before a sequence is chosen, and check the reference transcript (MANE Select in human; RefSeq Select and Ensembl canonical in mouse and rat) is the one your cells express.
03
Think across species early
The orthologs panel says whether mouse and rat carry the same gene. Whether one oligonucleotide can serve two species is a sequence question, settled at design by matching the candidate against each transcript, not by the protein identity shown there.
04
Check expression in your model
A transcript that is not expressed in your cells cannot show knockdown. Confirm the gene is expressed in the cell type and condition you will use, from your own data or a reference atlas, before the order. The expression panel above gives GTEx's median per tissue for a human gene; for mouse and rat it says that no atlas is on this page yet.

Gene Rat Rattus norvegicus

Ube2v2

Reading the record for Ube2v2 from NCBI Gene and Ensembl.Still reading. A first read of a gene can take a while; this page waits up to 115 seconds for it, and its scripts then bring in the page, or a line saying what did not arrive.

The full name, the identifiers, the location and the notes from the sources arrive with the record. Nothing is filled in ahead of it.

Order door

The door to order for Ube2v2 opens with the record, which decides which product it carries. The order page itself is open now.

Bring your own sequence

For research use only. Not for use in diagnostic or therapeutic procedures.

This page is still reading the record. Its scripts replace this shell with the record when it arrives; with scripts off, it stays at this shell however long you wait.

01 Summary and function

What Ube2v2 does

Waiting for the record before reading NCBI Gene and UniProt.

02 Transcripts and isoforms

The RNA a design targets

Waiting for the record before reading NCBI Datasets and Ensembl.

03 Expression by tissue

Where Ube2v2 is expressed

Waiting for the record before reading GTEx and the Human Protein Atlas.

04 Protein

The protein Ube2v2 encodes

Waiting for the record before reading UniProt, InterPro, AlphaFold DB and PDBe.

05 Interactions

Proteins STRING associates with Ube2v2

Waiting for the record before reading STRING.

06 Pathways

Where Ube2v2 acts, as Reactome curates it

Waiting for the record before reading UniProt and Reactome.

07 Disease associations

Diseases linked to Ube2v2

Waiting for the record before reading Open Targets and ClinGen.

08 Variants

Classified variants of Ube2v2

Waiting for the record before reading ClinVar.

09 Constraint

How much variation Ube2v2 tolerates

Waiting for the record before reading gnomAD and Open Targets.

10 Orthologs

The same gene in mouse, rat and human

Waiting for the record before reading the Alliance, NCBI, Ensembl Compara and RGD.

11 MicroRNAs

MicroRNAs hosted within Ube2v2

Waiting for the record before reading Ensembl and miRBase.

12 Long non-coding RNAs

Long non-coding RNAs at the Ube2v2 locus

Waiting for the record before reading Ensembl.

13 Literature

Papers that mention Ube2v2

Waiting for the record before reading Europe PMC.

Accession	Name	Biotype	Labels	Exons	Spliced length	Protein	Sequence
NM_183052.2	none given	protein coding	RefSeq Select	4	3,260 nt	145 aaNP_898875.1	Ready in a moment
XM_087635122.1matches ENSRNOT00000097423.2	transcript variant X3	protein coding model	none	4	1,585 nt	275 aaXP_087491248.1	Ready in a moment
XM_017597891.4	transcript variant X1	protein coding model	none	4	1,568 nt	160 aaXP_017453380.1	Ready in a moment
XM_039088057.3matches ENSRNOT00000111871.2	Ready in a moment

Accession	Name	Biotype	Labels	Exons	Spliced length	Protein	Sequence
NM_183052.2	none given	protein coding	RefSeq Select	4	3,260 nt	145 aaNP_898875.1	Ready in a moment
XM_087635122.1matches ENSRNOT00000097423.2	transcript variant X3	protein coding model	none	4	1,585 nt	275 aaXP_087491248.1	Ready in a moment
XM_017597891.4	transcript variant X1	protein coding model	none	4	1,568 nt	160 aaXP_017453380.1	Ready in a moment
XM_039088057.3matches ENSRNOT00000111871.2	Ready in a moment

Accession	Name	Biotype	Labels	Exons	Spliced length	Protein	Sequence
ENSRNOT00000097423.2	Ube2v2-202	protein coding	Ensembl canonical	5	1,782 nt	275 aaENSRNOP00000093767.2	Ready in a moment
ENSRNOT00000126693.1	Ube2v2-204	protein coding	none	4	3,868 nt	149 aaENSRNOP00000112218.1	Ready in a moment
ENSRNOT00000128196.1	Ube2v2-205	protein coding	none	4	3,847 nt	142 aaENSRNOP00000098888.1	Ready in a moment
ENSRNOT00000111871.2	Ube2v2-203	protein coding	none	5	1,272 nt	149 aaENSRNOP00000079261.2	Ready in a moment
ENSRNOT00000088212.3	Ube2v2-201	protein coding	none	3	344 nt	103 aaENSRNOP00000068914.2	Ready in a moment

Ube2v2

What Ube2v2 does

The RNA a design targets

From Ube2v2 to a sequence that silences it

Choose the region

Cover the isoforms you mean

Think across species early

Check expression in your model

Ube2v2

What Ube2v2 does

The RNA a design targets

Where Ube2v2 is expressed

The protein Ube2v2 encodes

Proteins STRING associates with Ube2v2

Where Ube2v2 acts, as Reactome curates it

Diseases linked to Ube2v2

Classified variants of Ube2v2

How much variation Ube2v2 tolerates

The same gene in mouse, rat and human

MicroRNAs hosted within Ube2v2

Long non-coding RNAs at the Ube2v2 locus

Papers that mention Ube2v2

Ube2v2

What Ube2v2 does

Gene summary

Protein function

The RNA a design targets

RefSeq 4 transcripts

A window on one transcript

Ensembl 5 transcripts

A window on one transcript

From Ube2v2 to a sequence that silences it

Choose the region

Cover the isoforms you mean

Think across species early

Check expression in your model

Where Ube2v2 is expressed

The protein Ube2v2 encodes

Proteins STRING associates with Ube2v2

Where Ube2v2 acts, as Reactome curates it

Diseases linked to Ube2v2

Classified variants of Ube2v2

How much variation Ube2v2 tolerates

The same gene in mouse, rat and human

MicroRNAs hosted within Ube2v2

Long non-coding RNAs at the Ube2v2 locus

Papers that mention Ube2v2

Run the controls

Pick the product

Gene summary

Protein function

RefSeq 4 transcripts

A window on one transcript

Ensembl 5 transcripts

A window on one transcript