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Configure your RNA-silencing products

Choose a product family, name the target or paste your sequence, then set purification and yield.

Self-delivering antisense, taken up by cells without a transfection reagent: AUMsilence, AUMantagomir, AUMlnc and AUMmimic sdASOs, designed to the targets you name or made from your own sequences.

Quotation request.

01 How do you want to start?

Name the targets, and the sequences are designed using the AUMsilence platform, screened and made.

02 Product
03 Species and long non-coding RNA

Official symbol, alias or previous symbol

04 Purification

Reverse-phase cartridge (RPC) or high-performance liquid chromatography (HPLC).

05 Delivered yield
06 Sequences per target

A sequence silences only where its window of the transcript is open, and which windows are open is settled by testing.

3 or 5 sequences?
  • 1 sequence is the right order when the sequence is already settled: a published design you are reproducing, or one you have used before.
  • 3 sequences are the standard first pass on a target nobody has silenced: enough to find a working sequence without spending the budget on one.
  • 5 sequences are for an experiment you cannot easily repeat: primary cells from one donor, an animal cohort, a transcript whose open windows are few.

Sequences per target

If none of the 5 reaches 70% knockdown of the target transcript under the protocol, AUM BioTech supplies 5 more, designed using the AUMsilence platform against the same target, at no charge, once. The terms say how a claim is made. Terms and conditions

Order the scramble control alongside every time, and a labeled scramble once per cell type.

07 Controls

A scramble control is recommended with every order; a labeled control shows uptake in your cells before the first experiment.

Positive control

An abundant nuclear lncRNA, to confirm uptake and knockdown.

Labeled scramble control

10 nmol, HPLC, $799. Fluorescent, to see uptake.