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Pathway Human Homo sapiens

ER to Golgi Anterograde Transport

R-HSA-199977 in Reactome release 97: under 2 parents, with 156 genes placed in it by the mapping files and 3 child pathways in the hierarchy.

The same number in the other species

Reactome writes the mouse and rat events it infers from a human pathway under the human number with the species token. A door opens only where that species' own list in this release holds the id: R-MMU-199977 (mouse), R-RNO-199977 (rat). Whether the event was inferred from this one is what the record says.

01The record

Reactome's own record of this pathway

What this tells you

The pathway list, the hierarchy and the genes on this page are read from the files Reactome publishes for Reactome release 97, built into this site on 2026-09-09: the pathway list, the hierarchy relationship file and the two gene mapping files. The record card is the one live read, Reactome's own record of this pathway.

Reactome's download page describes the mapping files: Mapping files link the source database identifier to the lowest level pathway diagram or subset of the pathway, all levels of the pathway hierarchy or database identifier to all reactions. [R13] The gene list here is the all-levels mapping of NCBI Gene ids, filled from the all-levels mapping of Ensembl ids where the NCBI file has no row for a gene; each row names which file it came from by the shape of its source id. Each row carries the evidence codes the file writes for it, as written and unranked, and both where the file writes both; no page of Reactome's documentation the survey read defines the codes, so this page does not expand them. A gene id the identity files do not name is kept as the source's own id with no door rather than turned into a symbol.

On citing what a search finds, Reactome says: It should be remembered that while we strive to contain the most current and accurate data, Reactome should not be used in citations where other primary sources of information are available. [R12] The record card prints the literature Reactome attaches to a curated pathway for that reason. The data are public domain: All data in the Reactome database and files derived from that data are licensed under the Creative Commons Public Domain Dedication (CC0). User may copy, modify, and distribute these data, even for commercial purposes, without asking for permission. Attribution is encouraged but not required. [R10] The pathway illustrations are licensed apart, under CC BY 4.0, and none is shown here.

A gene on this list is one Reactome places in this pathway in this release, and that is all the row says: it does not say the gene is expressed in a tissue or associated with a disease, which are the other two explorers' questions, read from other sources. Reactome's papers of record are [R01] [R02].

  1. [R01] Ragueneau E, Gong C, Sinquin P, Sevilla C, Beavers D, Grentner A, et al. (2026). The Reactome Knowledgebase 2026. Nucleic Acids Research 54:D673-D681. PMID 41251150, doi 10.1093/nar/gkaf1223.
  2. [R02] Milacic M, Beavers D, Conley P, Gong C, Gillespie M, Griss J, et al. (2024). The Reactome Pathway Knowledgebase 2024. Nucleic Acids Research 52:D672-D678. PMID 37941124, doi 10.1093/nar/gkad1025.
  3. [R10] Reactome, reactome.org. License Agreement. https://reactome.org/license, read 2026-09-09.
  4. [R12] Reactome, reactome.org. Citing us. https://reactome.org/cite, read 2026-09-09.
  5. [R13] Reactome, reactome.org. Download. https://reactome.org/download-data, read 2026-09-09.
Reading this pathway's record from Reactome (the pathway record).Still reading. A first read of a pathway can take a while; this page waits up to 35 seconds for it, and its scripts then bring in the panel, or a line saying what did not arrive.

02The genes

Genes Reactome places in this human pathway

The mapping files place 156 genes in this human pathway; showing 101 to 156, in pages of 100, sorted by symbol for reading. The order carries no ranking.

Genes Reactome places in this human pathway, page 2 of 2
GeneSEC24AAuthorityHGNC:10703Mapping file id10802 NCBI fileEvidenceTAS
GeneSEC24BAuthorityHGNC:10704Mapping file id10427 NCBI fileEvidenceTAS
GeneSEC24CAuthorityHGNC:10705Mapping file id9632 NCBI fileEvidenceTAS
GeneSEC24DAuthorityHGNC:10706Mapping file id9871 NCBI fileEvidenceTAS
GeneSEC31AAuthorityHGNC:17052Mapping file id22872 NCBI fileEvidenceTAS
GeneSEC31BAuthorityHGNC:23197Mapping file id25956 NCBI fileEvidenceTAS
GeneSERPINA1AuthorityHGNC:8941Mapping file id5265 NCBI fileEvidenceTAS
GeneSPTA1AuthorityHGNC:11272Mapping file id6708 NCBI fileEvidenceTAS
GeneSPTAN1AuthorityHGNC:11273Mapping file id6709 NCBI fileEvidenceTAS
GeneSPTBAuthorityHGNC:11274Mapping file id6710 NCBI fileEvidenceTAS
GeneSPTBN1AuthorityHGNC:11275Mapping file id6711 NCBI fileEvidenceTAS
GeneSPTBN2AuthorityHGNC:11276Mapping file id6712 NCBI fileEvidenceTAS
GeneSPTBN4AuthorityHGNC:14896Mapping file id57731 NCBI fileEvidenceTAS
GeneSPTBN5AuthorityHGNC:15680Mapping file id51332 NCBI fileEvidenceTAS
GeneSTX17AuthorityHGNC:11432Mapping file id55014 NCBI fileEvidenceTAS
GeneSTX5AuthorityHGNC:11440Mapping file id6811 NCBI fileEvidenceTAS
GeneTBC1D20AuthorityHGNC:16133Mapping file id128637 NCBI fileEvidenceTAS
GeneTFGAuthorityHGNC:11758Mapping file id10342 NCBI fileEvidenceTAS
GeneTGFAAuthorityHGNC:11765Mapping file id7039 NCBI fileEvidenceTAS
GeneTMED10AuthorityHGNC:16998Mapping file id10972 NCBI fileEvidenceTAS
GeneTMED2AuthorityHGNC:16996Mapping file id10959 NCBI fileEvidenceTAS
GeneTMED3AuthorityHGNC:28889Mapping file id23423 NCBI fileEvidenceTAS
GeneTMED7AuthorityHGNC:24253Mapping file id51014 NCBI fileEvidenceTAS
GeneTMED9AuthorityHGNC:24878Mapping file id54732 NCBI fileEvidenceTAS
GeneTMEM115AuthorityHGNC:30055Mapping file id11070 NCBI fileEvidenceTAS
GeneTRAPPC1AuthorityHGNC:19894Mapping file id58485 NCBI fileEvidenceTAS
GeneTRAPPC10AuthorityHGNC:11868Mapping file id7109 NCBI fileEvidenceTAS
GeneTRAPPC2AuthorityHGNC:23068Mapping file id6399 NCBI fileEvidenceTAS
GeneTRAPPC2LAuthorityHGNC:30887Mapping file id51693 NCBI fileEvidenceTAS
GeneTRAPPC3AuthorityHGNC:19942Mapping file id27095 NCBI fileEvidenceTAS
GeneTRAPPC4AuthorityHGNC:19943Mapping file id51399 NCBI fileEvidenceTAS
GeneTRAPPC5AuthorityHGNC:23067Mapping file id126003 NCBI fileEvidenceTAS
GeneTRAPPC6AAuthorityHGNC:23069Mapping file id79090 NCBI fileEvidenceTAS
GeneTRAPPC6BAuthorityHGNC:23066Mapping file id122553 NCBI fileEvidenceTAS
GeneTRAPPC9AuthorityHGNC:30832Mapping file id83696 NCBI fileEvidenceTAS
GeneTUBA1AAuthorityHGNC:20766Mapping file id7846 NCBI fileEvidenceTAS
GeneTUBA1BAuthorityHGNC:18809Mapping file id10376 NCBI fileEvidenceTAS
GeneTUBA1CAuthorityHGNC:20768Mapping file id84790 NCBI fileEvidenceTAS
GeneTUBA3CAuthorityHGNC:12408Mapping file id7278 NCBI fileEvidenceTAS
GeneTUBA3DAuthorityHGNC:24071Mapping file id113457 NCBI fileEvidenceTAS
GeneTUBA3EAuthorityHGNC:20765Mapping file id112714 NCBI fileEvidenceTAS
GeneTUBA4AAuthorityHGNC:12407Mapping file id7277 NCBI fileEvidenceTAS
GeneTUBA4BAuthorityHGNC:18637Mapping file id80086 NCBI fileEvidenceTAS
GeneTUBA8AuthorityHGNC:12410Mapping file id51807 NCBI fileEvidenceTAS
GeneTUBAL3AuthorityHGNC:23534Mapping file id79861 NCBI fileEvidenceTAS
GeneTUBB1AuthorityHGNC:16257Mapping file id81027 NCBI fileEvidenceTAS
GeneTUBB2AAuthorityHGNC:12412Mapping file id7280 NCBI fileEvidenceTAS
GeneTUBB2BAuthorityHGNC:30829Mapping file id347733 NCBI fileEvidenceTAS
GeneTUBB3AuthorityHGNC:20772Mapping file id10381 NCBI fileEvidenceTAS
GeneTUBB4AAuthorityHGNC:20774Mapping file id10382 NCBI fileEvidenceTAS
GeneTUBB4BAuthorityHGNC:20771Mapping file id10383 NCBI fileEvidenceTAS
GeneTUBB6AuthorityHGNC:20776Mapping file id84617 NCBI fileEvidenceTAS
GeneTUBB8AuthorityHGNC:20773Mapping file id347688 NCBI fileEvidenceTAS
GeneTUBB8BAuthorityHGNC:24983Mapping file id260334 NCBI fileEvidenceTAS
GeneUSO1AuthorityHGNC:30904Mapping file id8615 NCBI fileEvidenceTAS
GeneYKT6AuthorityHGNC:16959Mapping file id10652 NCBI fileEvidenceTAS

Evidence codes on this page: TAS, as the mapping file writes them; a row carrying two was written twice by the file, once under each. The mapping file id says which file placed the gene: an NCBI Gene id from NCBI2Reactome_All_Levels.txt, an Ensembl gene id from Ensembl2Reactome_All_Levels.txt. The two files can disagree about a code, so a row's codes are the one file's view. Measured by this site's build over this release on 2026-09-09: of the 138,908 human pathway-gene pairs both files place, 207 (0.149 per cent, over 47 genes) carry TAS in the Ensembl file where the NCBI rows carry IEA alone.

  • Reactome mapping files, the human rows for this pathway · Reactome release 97 · read · Reactome downloads"NCBI2Reactome_All_Levels.txt" and "Ensembl2Reactome_All_Levels.txt", Reactome, release 97, https://reactome.org/download-data/ (date of access 2026-09-09). Data CC0; attribution encouraged.

03The hierarchy

Parents and children in this release's hierarchy

Reactome's hierarchy is a graph rather than a tree: a pathway can sit under more than one parent, and the gene counts are each pathway's own placements at every level under it, so a parent's count is not the sum of its children's.

  • Reactome, the human pathway list and hierarchy relationship file · Reactome release 97 · read · Reactome downloads"ReactomePathways.txt" and "ReactomePathwaysRelation.txt", Reactome, release 97, https://reactome.org/download-data/ (date of access 2026-09-09). Data CC0; attribution encouraged.