Pathway Human Homo sapiens
Olfactory Signaling Pathway
R-HSA-381753 in Reactome release 97: under Sensory Perception, with 418 genes placed in it by the mapping files and 1 child pathway in the hierarchy.
The same number in the other species
Reactome writes the mouse and rat events it infers from a human pathway under the human number with the species token. A door opens only where that species' own list in this release holds the id: R-MMU-381753 (mouse). Whether the event was inferred from this one is what the record says.
01The record
Reactome's own record of this pathway
What this tells you
The pathway list, the hierarchy and the genes on this page are read from the files Reactome publishes for Reactome release 97, built into this site on 2026-09-09: the pathway list, the hierarchy relationship file and the two gene mapping files. The record card is the one live read, Reactome's own record of this pathway.
Reactome's download page describes the mapping files: Mapping files link the source database identifier to the lowest level pathway diagram or subset of the pathway, all levels of the pathway hierarchy or database identifier to all reactions.
[R13] The gene list here is the all-levels mapping of NCBI Gene ids, filled from the all-levels mapping of Ensembl ids where the NCBI file has no row for a gene; each row names which file it came from by the shape of its source id. Each row carries the evidence codes the file writes for it, as written and unranked, and both where the file writes both; no page of Reactome's documentation the survey read defines the codes, so this page does not expand them. A gene id the identity files do not name is kept as the source's own id with no door rather than turned into a symbol.
On citing what a search finds, Reactome says: It should be remembered that while we strive to contain the most current and accurate data, Reactome should not be used in citations where other primary sources of information are available.
[R12] The record card prints the literature Reactome attaches to a curated pathway for that reason. The data are public domain: All data in the Reactome database and files derived from that data are licensed under the Creative Commons Public Domain Dedication (CC0). User may copy, modify, and distribute these data, even for commercial purposes, without asking for permission. Attribution is encouraged but not required.
[R10] The pathway illustrations are licensed apart, under CC BY 4.0, and none is shown here.
A gene on this list is one Reactome places in this pathway in this release, and that is all the row says: it does not say the gene is expressed in a tissue or associated with a disease, which are the other two explorers' questions, read from other sources. Reactome's papers of record are [R01] [R02].
- [R01] Ragueneau E, Gong C, Sinquin P, Sevilla C, Beavers D, Grentner A, et al. (2026). The Reactome Knowledgebase 2026. Nucleic Acids Research 54:D673-D681. PMID 41251150, doi 10.1093/nar/gkaf1223.
- [R02] Milacic M, Beavers D, Conley P, Gong C, Gillespie M, Griss J, et al. (2024). The Reactome Pathway Knowledgebase 2024. Nucleic Acids Research 52:D672-D678. PMID 37941124, doi 10.1093/nar/gkad1025.
- [R10] Reactome, reactome.org. License Agreement. https://reactome.org/license, read 2026-09-09.
- [R12] Reactome, reactome.org. Citing us. https://reactome.org/cite, read 2026-09-09.
- [R13] Reactome, reactome.org. Download. https://reactome.org/download-data, read 2026-09-09.
02The genes
Genes Reactome places in this human pathway
The mapping files place 418 genes in this human pathway; showing 101 to 200, in pages of 100, sorted by symbol for reading. The order carries no ranking.
| Gene | Authority id | Mapping file id | Evidence codes |
|---|---|---|---|
| GeneOR1M1 | AuthorityHGNC:8220 | Mapping file id125963 NCBI file | EvidenceIEA |
| GeneOR1N1 | AuthorityHGNC:8221 | Mapping file id138883 NCBI file | EvidenceIEA |
| GeneOR1N2 | AuthorityHGNC:15111 | Mapping file id138882 NCBI file | EvidenceIEA, TAS |
| GeneOR1P1 | AuthorityHGNC:8222 | Mapping file idENSG00000262085 Ensembl file | EvidenceIEA |
| GeneOR1Q1 | AuthorityHGNC:8223 | Mapping file id158131 NCBI file | EvidenceIEA |
| GeneOR1S1 | AuthorityHGNC:8227 | Mapping file id219959 NCBI file | EvidenceIEA |
| GeneOR1S2 | AuthorityHGNC:15141 | Mapping file id219958 NCBI file | EvidenceIEA |
| GeneOR2A1 | AuthorityHGNC:8229 | Mapping file id346528 NCBI file | EvidenceIEA, TAS |
| GeneOR2A12 | AuthorityHGNC:15082 | Mapping file id346525 NCBI file | EvidenceIEA |
| GeneOR2A14 | AuthorityHGNC:15084 | Mapping file id135941 NCBI file | EvidenceIEA |
| GeneOR2A2 | AuthorityHGNC:8230 | Mapping file id442361 NCBI file | EvidenceIEA |
| GeneOR2A25 | AuthorityHGNC:19562 | Mapping file id392138 NCBI file | EvidenceIEA, TAS |
| GeneOR2A4 | AuthorityHGNC:14729 | Mapping file id79541 NCBI file | EvidenceIEA |
| GeneOR2A42 | AuthorityHGNC:31230 | Mapping file id402317 NCBI file | EvidenceIEA, TAS |
| GeneOR2A5 | AuthorityHGNC:8232 | Mapping file id393046 NCBI file | EvidenceIEA |
| GeneOR2A7 | AuthorityHGNC:8234 | Mapping file id401427 NCBI file | EvidenceIEA, TAS |
| GeneOR2AE1 | AuthorityHGNC:15087 | Mapping file id81392 NCBI file | EvidenceIEA |
| GeneOR2AG1 | AuthorityHGNC:15142 | Mapping file id144125 NCBI file | EvidenceIEA |
| GeneOR2AG2 | AuthorityHGNC:15143 | Mapping file id338755 NCBI file | EvidenceIEA |
| GeneOR2AJ1 | AuthorityHGNC:15001 | Mapping file id127608 NCBI file | EvidenceIEA |
| GeneOR2AK2 | AuthorityHGNC:19569 | Mapping file id391191 NCBI file | EvidenceIEA |
| GeneOR2AP1 | AuthorityHGNC:15335 | Mapping file id121129 NCBI file | EvidenceIEA |
| GeneOR2AT4 | AuthorityHGNC:19620 | Mapping file id341152 NCBI file | EvidenceIEA, TAS |
| GeneOR2B11 | AuthorityHGNC:31249 | Mapping file id127623 NCBI file | EvidenceIEA, TAS |
| GeneOR2B2 | AuthorityHGNC:13966 | Mapping file id81697 NCBI file | EvidenceIEA |
| GeneOR2B3 | AuthorityHGNC:8238 | Mapping file id442184 NCBI file | EvidenceIEA |
| GeneOR2B6 | AuthorityHGNC:8241 | Mapping file id26212 NCBI file | EvidenceIEA |
| GeneOR2C1 | AuthorityHGNC:8242 | Mapping file id4993 NCBI file | EvidenceIEA, TAS |
| GeneOR2C3 | AuthorityHGNC:15005 | Mapping file id81472 NCBI file | EvidenceIEA |
| GeneOR2D2 | AuthorityHGNC:8244 | Mapping file id120776 NCBI file | EvidenceIEA |
| GeneOR2D3 | AuthorityHGNC:15146 | Mapping file id120775 NCBI file | EvidenceIEA |
| GeneOR2F1 | AuthorityHGNC:8246 | Mapping file id26211 NCBI file | EvidenceIEA, TAS |
| GeneOR2F2 | AuthorityHGNC:8247 | Mapping file id135948 NCBI file | EvidenceIEA |
| GeneOR2G2 | AuthorityHGNC:15007 | Mapping file id81470 NCBI file | EvidenceIEA |
| GeneOR2G3 | AuthorityHGNC:15008 | Mapping file id81469 NCBI file | EvidenceIEA |
| GeneOR2G6 | AuthorityHGNC:27019 | Mapping file id391211 NCBI file | EvidenceIEA |
| GeneOR2H1 | AuthorityHGNC:8252 | Mapping file id26716 NCBI file | EvidenceIEA |
| GeneOR2H2 | AuthorityHGNC:8253 | Mapping file id7932 NCBI file | EvidenceIEA |
| GeneOR2I1 | AuthorityHGNC:8258 | Mapping file id442197 NCBI file | EvidenceIEA |
| GeneOR2J1 | AuthorityHGNC:8259 | Mapping file id442185 NCBI file | EvidenceIEA, TAS |
| GeneOR2J2 | AuthorityHGNC:8260 | Mapping file id26707 NCBI file | EvidenceIEA, TAS |
| GeneOR2J3 | AuthorityHGNC:8261 | Mapping file id442186 NCBI file | EvidenceIEA, TAS |
| GeneOR2K2 | AuthorityHGNC:8264 | Mapping file id26248 NCBI file | EvidenceIEA |
| GeneOR2L13 | AuthorityHGNC:19578 | Mapping file id284521 NCBI file | EvidenceIEA, TAS |
| GeneOR2L2 | AuthorityHGNC:8266 | Mapping file id26246 NCBI file | EvidenceIEA |
| GeneOR2L3 | AuthorityHGNC:15009 | Mapping file id391192 NCBI file | EvidenceIEA |
| GeneOR2L5 | AuthorityHGNC:15011 | Mapping file id81466 NCBI file | EvidenceIEA |
| GeneOR2L8 | AuthorityHGNC:15014 | Mapping file id391190 NCBI file | EvidenceIEA |
| GeneOR2M2 | AuthorityHGNC:8268 | Mapping file id391194 NCBI file | EvidenceIEA, TAS |
| GeneOR2M3 | AuthorityHGNC:8269 | Mapping file id127062 NCBI file | EvidenceIEA |
| GeneOR2M4 | AuthorityHGNC:8270 | Mapping file id26245 NCBI file | EvidenceIEA |
| GeneOR2M5 | AuthorityHGNC:19576 | Mapping file id127059 NCBI file | EvidenceIEA |
| GeneOR2M7 | AuthorityHGNC:19594 | Mapping file id391196 NCBI file | EvidenceIEA, TAS |
| GeneOR2S2 | AuthorityHGNC:8276 | Mapping file id56656 NCBI file | EvidenceIEA, TAS |
| GeneOR2T1 | AuthorityHGNC:8277 | Mapping file id26696 NCBI file | EvidenceIEA, TAS |
| GeneOR2T10 | AuthorityHGNC:19573 | Mapping file id127069 NCBI file | EvidenceIEA |
| GeneOR2T11 | AuthorityHGNC:19574 | Mapping file id127077 NCBI file | EvidenceIEA |
| GeneOR2T12 | AuthorityHGNC:19592 | Mapping file id127064 NCBI file | EvidenceIEA |
| GeneOR2T2 | AuthorityHGNC:14725 | Mapping file id401992 NCBI file | EvidenceIEA |
| GeneOR2T27 | AuthorityHGNC:31252 | Mapping file id403239 NCBI file | EvidenceIEA |
| GeneOR2T29 | AuthorityHGNC:31253 | Mapping file id343563 NCBI file | EvidenceIEA |
| GeneOR2T3 | AuthorityHGNC:14727 | Mapping file id343173 NCBI file | EvidenceIEA |
| GeneOR2T33 | AuthorityHGNC:31255 | Mapping file id391195 NCBI file | EvidenceIEA |
| GeneOR2T34 | AuthorityHGNC:31256 | Mapping file id127068 NCBI file | EvidenceIEA |
| GeneOR2T35 | AuthorityHGNC:31257 | Mapping file id403244 NCBI file | EvidenceIEA |
| GeneOR2T4 | AuthorityHGNC:15016 | Mapping file id127074 NCBI file | EvidenceIEA, TAS |
| GeneOR2T5 | AuthorityHGNC:15017 | Mapping file id401993 NCBI file | EvidenceIEA |
| GeneOR2T6 | AuthorityHGNC:15018 | Mapping file id254879 NCBI file | EvidenceIEA |
| GeneOR2T7 | AuthorityHGNC:15019 | Mapping file idENSG00000227152 Ensembl file | EvidenceIEA |
| GeneOR2T8 | AuthorityHGNC:15020 | Mapping file id343172 NCBI file | EvidenceIEA |
| GeneOR2V1 | AuthorityHGNC:8280 | Mapping file id26693 NCBI file | EvidenceIEA |
| GeneOR2V2 | AuthorityHGNC:15341 | Mapping file id285659 NCBI file | EvidenceIEA |
| GeneOR2W1 | AuthorityHGNC:8281 | Mapping file id26692 NCBI file | EvidenceIEA, TAS |
| GeneOR2W3 | AuthorityHGNC:15021 | Mapping file id343171 NCBI file | EvidenceIEA, TAS |
| GeneOR2Y1 | AuthorityHGNC:14837 | Mapping file id134083 NCBI file | EvidenceIEA |
| GeneOR2Z1 | AuthorityHGNC:15391 | Mapping file id284383 NCBI file | EvidenceIEA |
| GeneOR3A1 | AuthorityHGNC:8282 | Mapping file id4994 NCBI file | EvidenceIEA, TAS |
| GeneOR3A2 | AuthorityHGNC:8283 | Mapping file id4995 NCBI file | EvidenceIEA |
| GeneOR3A3 | AuthorityHGNC:8284 | Mapping file id8392 NCBI file | EvidenceIEA |
| GeneOR4A15 | AuthorityHGNC:15152 | Mapping file id81328 NCBI file | EvidenceIEA |
| GeneOR4A16 | AuthorityHGNC:15153 | Mapping file id81327 NCBI file | EvidenceIEA |
| GeneOR4A47 | AuthorityHGNC:31266 | Mapping file id403253 NCBI file | EvidenceIEA |
| GeneOR4A5 | AuthorityHGNC:15162 | Mapping file id81318 NCBI file | EvidenceIEA |
| GeneOR4A8 | AuthorityHGNC:15165 | Mapping file idENSG00000225997 Ensembl file | EvidenceIEA |
| GeneOR4B1 | AuthorityHGNC:8290 | Mapping file id119765 NCBI file | EvidenceIEA |
| GeneOR4C11 | AuthorityHGNC:15167 | Mapping file id219429 NCBI file | EvidenceIEA |
| GeneOR4C12 | AuthorityHGNC:15168 | Mapping file id283093 NCBI file | EvidenceIEA, TAS |
| GeneOR4C13 | AuthorityHGNC:15169 | Mapping file id283092 NCBI file | EvidenceIEA |
| GeneOR4C15 | AuthorityHGNC:15171 | Mapping file id81309 NCBI file | EvidenceIEA |
| GeneOR4C16 | AuthorityHGNC:15172 | Mapping file id219428 NCBI file | EvidenceIEA |
| GeneOR4C3 | AuthorityHGNC:14697 | Mapping file id256144 NCBI file | EvidenceIEA |
| GeneOR4C45 | AuthorityHGNC:31270 | Mapping file id403257 NCBI file | EvidenceIEA |
| GeneOR4C46 | AuthorityHGNC:31271 | Mapping file id119749 NCBI file | EvidenceIEA |
| GeneOR4C5 | AuthorityHGNC:14702 | Mapping file id79346 NCBI file | EvidenceIEA |
| GeneOR4C6 | AuthorityHGNC:14743 | Mapping file id219432 NCBI file | EvidenceIEA |
| GeneOR4D1 | AuthorityHGNC:8293 | Mapping file id26689 NCBI file | EvidenceIEA |
| GeneOR4D10 | AuthorityHGNC:15173 | Mapping file id390197 NCBI file | EvidenceIEA |
| GeneOR4D11 | AuthorityHGNC:15174 | Mapping file id219986 NCBI file | EvidenceIEA |
| GeneOR4D2 | AuthorityHGNC:8294 | Mapping file id124538 NCBI file | EvidenceIEA, TAS |
| GeneOR4D5 | AuthorityHGNC:14852 | Mapping file id219875 NCBI file | EvidenceIEA |
Evidence codes on this page: IEA, TAS, as the mapping file writes them; a row carrying two was written twice by the file, once under each. The mapping file id says which file placed the gene: an NCBI Gene id from NCBI2Reactome_All_Levels.txt, an Ensembl gene id from Ensembl2Reactome_All_Levels.txt. The two files can disagree about a code, so a row's codes are the one file's view. Measured by this site's build over this release on 2026-09-09: of the 138,908 human pathway-gene pairs both files place, 207 (0.149 per cent, over 47 genes) carry TAS in the Ensembl file where the NCBI rows carry IEA alone.
- Reactome mapping files, the human rows for this pathway · Reactome release 97 · read · Reactome downloads"NCBI2Reactome_All_Levels.txt" and "Ensembl2Reactome_All_Levels.txt", Reactome, release 97, https://reactome.org/download-data/ (date of access 2026-09-09). Data CC0; attribution encouraged.
03The hierarchy
Parents and children in this release's hierarchy
Reactome's hierarchy is a graph rather than a tree: a pathway can sit under more than one parent, and the gene counts are each pathway's own placements at every level under it, so a parent's count is not the sum of its children's.
- Reactome, the human pathway list and hierarchy relationship file · Reactome release 97 · read · Reactome downloads"ReactomePathways.txt" and "ReactomePathwaysRelation.txt", Reactome, release 97, https://reactome.org/download-data/ (date of access 2026-09-09). Data CC0; attribution encouraged.