Pathway Human Homo sapiens
Sensory Perception
R-HSA-9709957 in Reactome release 97: a top-level pathway, with 641 genes placed in it by the mapping files and 4 child pathways in the hierarchy.
The same number in the other species
Reactome writes the mouse and rat events it infers from a human pathway under the human number with the species token. A door opens only where that species' own list in this release holds the id: R-MMU-9709957 (mouse), R-RNO-9709957 (rat). Whether the event was inferred from this one is what the record says.
01The record
Reactome's own record of this pathway
What this tells you
The pathway list, the hierarchy and the genes on this page are read from the files Reactome publishes for Reactome release 97, built into this site on 2026-09-09: the pathway list, the hierarchy relationship file and the two gene mapping files. The record card is the one live read, Reactome's own record of this pathway.
Reactome's download page describes the mapping files: Mapping files link the source database identifier to the lowest level pathway diagram or subset of the pathway, all levels of the pathway hierarchy or database identifier to all reactions.
[R13] The gene list here is the all-levels mapping of NCBI Gene ids, filled from the all-levels mapping of Ensembl ids where the NCBI file has no row for a gene; each row names which file it came from by the shape of its source id. Each row carries the evidence codes the file writes for it, as written and unranked, and both where the file writes both; no page of Reactome's documentation the survey read defines the codes, so this page does not expand them. A gene id the identity files do not name is kept as the source's own id with no door rather than turned into a symbol.
On citing what a search finds, Reactome says: It should be remembered that while we strive to contain the most current and accurate data, Reactome should not be used in citations where other primary sources of information are available.
[R12] The record card prints the literature Reactome attaches to a curated pathway for that reason. The data are public domain: All data in the Reactome database and files derived from that data are licensed under the Creative Commons Public Domain Dedication (CC0). User may copy, modify, and distribute these data, even for commercial purposes, without asking for permission. Attribution is encouraged but not required.
[R10] The pathway illustrations are licensed apart, under CC BY 4.0, and none is shown here.
A gene on this list is one Reactome places in this pathway in this release, and that is all the row says: it does not say the gene is expressed in a tissue or associated with a disease, which are the other two explorers' questions, read from other sources. Reactome's papers of record are [R01] [R02].
- [R01] Ragueneau E, Gong C, Sinquin P, Sevilla C, Beavers D, Grentner A, et al. (2026). The Reactome Knowledgebase 2026. Nucleic Acids Research 54:D673-D681. PMID 41251150, doi 10.1093/nar/gkaf1223.
- [R02] Milacic M, Beavers D, Conley P, Gong C, Gillespie M, Griss J, et al. (2024). The Reactome Pathway Knowledgebase 2024. Nucleic Acids Research 52:D672-D678. PMID 37941124, doi 10.1093/nar/gkad1025.
- [R10] Reactome, reactome.org. License Agreement. https://reactome.org/license, read 2026-09-09.
- [R12] Reactome, reactome.org. Citing us. https://reactome.org/cite, read 2026-09-09.
- [R13] Reactome, reactome.org. Download. https://reactome.org/download-data, read 2026-09-09.
02The genes
Genes Reactome places in this human pathway
The mapping files place 641 genes in this human pathway; showing 1 to 100, in pages of 100, sorted by symbol for reading. The order carries no ranking.
| Gene | Authority id | Mapping file id | Evidence codes |
|---|---|---|---|
| GeneABCA4 | AuthorityHGNC:34 | Mapping file id24 NCBI file | EvidenceIEA, TAS |
| GeneACTB | AuthorityHGNC:132 | Mapping file id60 NCBI file | EvidenceIEA |
| GeneACTG1 | AuthorityHGNC:144 | Mapping file id71 NCBI file | EvidenceIEA |
| GeneADCY3 | AuthorityHGNC:234 | Mapping file id109 NCBI file | EvidenceIEA |
| GeneAGRN | AuthorityHGNC:329 | Mapping file id375790 NCBI file | EvidenceTAS |
| GeneAKR1B10 | AuthorityHGNC:382 | Mapping file id57016 NCBI file | EvidenceTAS |
| GeneAKR1C1 | AuthorityHGNC:384 | Mapping file id1645 NCBI file | EvidenceTAS |
| GeneAKR1C3 | AuthorityHGNC:386 | Mapping file id8644 NCBI file | EvidenceTAS |
| GeneAKR1C4 | AuthorityHGNC:387 | Mapping file id1109 NCBI file | EvidenceTAS |
| GeneANO2 | AuthorityHGNC:1183 | Mapping file id57101 NCBI file | EvidenceIEA |
| GeneAPOA1 | AuthorityHGNC:600 | Mapping file id335 NCBI file | EvidenceIEA, TAS |
| GeneAPOA2 | AuthorityHGNC:601 | Mapping file id336 NCBI file | EvidenceIEA, TAS |
| GeneAPOA4 | AuthorityHGNC:602 | Mapping file id337 NCBI file | EvidenceIEA, TAS |
| GeneAPOB | AuthorityHGNC:603 | Mapping file id338 NCBI file | EvidenceIEA, TAS |
| GeneAPOC2 | AuthorityHGNC:609 | Mapping file id344 NCBI file | EvidenceIEA, TAS |
| GeneAPOC3 | AuthorityHGNC:610 | Mapping file id345 NCBI file | EvidenceIEA, TAS |
| GeneAPOE | AuthorityHGNC:613 | Mapping file id348 NCBI file | EvidenceIEA, TAS |
| GeneAPOM | AuthorityHGNC:13916 | Mapping file id55937 NCBI file | EvidenceTAS |
| GeneATP2B1 | AuthorityHGNC:814 | Mapping file id490 NCBI file | EvidenceIEA |
| GeneATP2B2 | AuthorityHGNC:815 | Mapping file id491 NCBI file | EvidenceIEA |
| GeneAWAT2 | AuthorityHGNC:23251 | Mapping file id158835 NCBI file | EvidenceTAS |
| GeneBCO1 | AuthorityHGNC:13815 | Mapping file id53630 NCBI file | EvidenceTAS |
| GeneBCO2 | AuthorityHGNC:18503 | Mapping file id83875 NCBI file | EvidenceTAS |
| GeneBSN | AuthorityHGNC:1117 | Mapping file id8927 NCBI file | EvidenceIEA |
| GeneCABP1 | AuthorityHGNC:1384 | Mapping file id9478 NCBI file | EvidenceIEA |
| GeneCABP2 | AuthorityHGNC:1385 | Mapping file id51475 NCBI file | EvidenceIEA |
| GeneCACNA1D | AuthorityHGNC:1391 | Mapping file id776 NCBI file | EvidenceIEA |
| GeneCACNA2D2 | AuthorityHGNC:1400 | Mapping file id9254 NCBI file | EvidenceIEA |
| GeneCACNB2 | AuthorityHGNC:1402 | Mapping file id783 NCBI file | EvidenceIEA |
| GeneCALHM1 | AuthorityHGNC:23494 | Mapping file id255022 NCBI file | EvidenceIEA |
| GeneCALHM3 | AuthorityHGNC:23458 | Mapping file id119395 NCBI file | EvidenceIEA |
| GeneCALM1 | AuthorityHGNC:1442 | Mapping file id801 NCBI file | EvidenceIEA, TAS |
| GeneCALM2 | AuthorityHGNC:1445 | Mapping file id805 NCBI file | EvidenceIEA, TAS |
| GeneCALM3 | AuthorityHGNC:1449 | Mapping file id808 NCBI file | EvidenceIEA, TAS |
| GeneCAMKMT | AuthorityHGNC:26276 | Mapping file id79823 NCBI file | EvidenceTAS |
| GeneCAPZA1 | AuthorityHGNC:1488 | Mapping file id829 NCBI file | EvidenceIEA |
| GeneCAPZA2 | AuthorityHGNC:1490 | Mapping file id830 NCBI file | EvidenceIEA |
| GeneCAPZB | AuthorityHGNC:1491 | Mapping file id832 NCBI file | EvidenceIEA |
| GeneCASK | AuthorityHGNC:1497 | Mapping file id8573 NCBI file | EvidenceIEA |
| GeneCDH23 | AuthorityHGNC:13733 | Mapping file id64072 NCBI file | EvidenceIEA |
| GeneCHRNA10 | AuthorityHGNC:13800 | Mapping file id57053 NCBI file | EvidenceIEA |
| GeneCHRNA9 | AuthorityHGNC:14079 | Mapping file id55584 NCBI file | EvidenceIEA |
| GeneCHURC1-FNTB | AuthorityHGNC:42960 | Mapping file id100529261 NCBI file | EvidenceTAS |
| GeneCIB2 | AuthorityHGNC:24579 | Mapping file id10518 NCBI file | EvidenceIEA |
| GeneCLIC5 | AuthorityHGNC:13517 | Mapping file id53405 NCBI file | EvidenceIEA |
| GeneCLPS | AuthorityHGNC:2085 | Mapping file id1208 NCBI file | EvidenceTAS |
| GeneCNGA1 | AuthorityHGNC:2148 | Mapping file id1259 NCBI file | EvidenceTAS |
| GeneCNGA2 | AuthorityHGNC:2149 | Mapping file id1260 NCBI file | EvidenceIEA |
| GeneCNGA4 | AuthorityHGNC:2152 | Mapping file id1262 NCBI file | EvidenceIEA |
| GeneCNGB1 | AuthorityHGNC:2151 | Mapping file id1258 NCBI file | EvidenceIEA, TAS |
| GeneCTBP2 | AuthorityHGNC:2495 | Mapping file id1488 NCBI file | EvidenceIEA |
| GeneCYP4V2 | AuthorityHGNC:23198 | Mapping file id285440 NCBI file | EvidenceTAS |
| GeneDHRS3 | AuthorityHGNC:17693 | Mapping file id9249 NCBI file | EvidenceTAS |
| GeneDHRS9 | AuthorityHGNC:16888 | Mapping file id10170 NCBI file | EvidenceTAS |
| GeneDNAJC5 | AuthorityHGNC:16235 | Mapping file id80331 NCBI file | EvidenceIEA |
| GeneEBF1 | AuthorityHGNC:3126 | Mapping file id1879 NCBI file | EvidenceIEA |
| GeneEPB41L1 | AuthorityHGNC:3378 | Mapping file id2036 NCBI file | EvidenceIEA |
| GeneEPB41L3 | AuthorityHGNC:3380 | Mapping file id23136 NCBI file | EvidenceIEA |
| GeneEPS8 | AuthorityHGNC:3420 | Mapping file id2059 NCBI file | EvidenceIEA |
| GeneEPS8L2 | AuthorityHGNC:21296 | Mapping file id64787 NCBI file | EvidenceIEA |
| GeneESPN | AuthorityHGNC:13281 | Mapping file id83715 NCBI file | EvidenceIEA |
| GeneESPNL | AuthorityHGNC:27937 | Mapping file id339768 NCBI file | EvidenceIEA |
| GeneEZR | AuthorityHGNC:12691 | Mapping file id7430 NCBI file | EvidenceIEA |
| GeneFNTA | AuthorityHGNC:3782 | Mapping file id2339 NCBI file | EvidenceTAS |
| GeneFNTB | AuthorityHGNC:3785 | Mapping file id2342 NCBI file | EvidenceTAS |
| GeneFSCN2 | AuthorityHGNC:3960 | Mapping file id25794 NCBI file | EvidenceIEA |
| GeneGNAL | AuthorityHGNC:4388 | Mapping file id2774 NCBI file | EvidenceIEA, TAS |
| GeneGNAT1 | AuthorityHGNC:4393 | Mapping file id2779 NCBI file | EvidenceIEA, TAS |
| GeneGNAT3 | AuthorityHGNC:22800 | Mapping file id346562 NCBI file | EvidenceIEA, TAS |
| GeneGNB1 | AuthorityHGNC:4396 | Mapping file id2782 NCBI file | EvidenceIEA, TAS |
| GeneGNB3 | AuthorityHGNC:4400 | Mapping file id2784 NCBI file | EvidenceIEA, TAS |
| GeneGNB5 | AuthorityHGNC:4401 | Mapping file id10681 NCBI file | EvidenceIEA, TAS |
| GeneGNG13 | AuthorityHGNC:14131 | Mapping file id51764 NCBI file | EvidenceIEA, TAS |
| GeneGNGT1 | AuthorityHGNC:4411 | Mapping file id2792 NCBI file | EvidenceIEA, TAS |
| GeneGPC1 | AuthorityHGNC:4449 | Mapping file id2817 NCBI file | EvidenceTAS |
| GeneGPC2 | AuthorityHGNC:4450 | Mapping file id221914 NCBI file | EvidenceTAS |
| GeneGPC3 | AuthorityHGNC:4451 | Mapping file id2719 NCBI file | EvidenceTAS |
| GeneGPC4 | AuthorityHGNC:4452 | Mapping file id2239 NCBI file | EvidenceTAS |
| GeneGPC5 | AuthorityHGNC:4453 | Mapping file id2262 NCBI file | EvidenceTAS |
| GeneGPC6 | AuthorityHGNC:4454 | Mapping file id10082 NCBI file | EvidenceTAS |
| GeneGPIHBP1 | AuthorityHGNC:24945 | Mapping file id338328 NCBI file | EvidenceTAS |
| GeneGRK1 | AuthorityHGNC:10013 | Mapping file id6011 NCBI file | EvidenceIEA, TAS |
| GeneGRK4 | AuthorityHGNC:4543 | Mapping file id2868 NCBI file | EvidenceTAS |
| GeneGRK7 | AuthorityHGNC:17031 | Mapping file id131890 NCBI file | EvidenceTAS |
| GeneGRM1 | AuthorityHGNC:4593 | Mapping file id2911 NCBI file | EvidenceIEA |
| GeneGRM4 | AuthorityHGNC:4596 | Mapping file id2914 NCBI file | EvidenceIEA |
| GeneGRXCR1 | AuthorityHGNC:31673 | Mapping file id389207 NCBI file | EvidenceIEA |
| GeneGRXCR2 | AuthorityHGNC:33862 | Mapping file id643226 NCBI file | EvidenceIEA |
| GeneGSN | AuthorityHGNC:4620 | Mapping file id2934 NCBI file | EvidenceIEA |
| GeneGUCA1A | AuthorityHGNC:4678 | Mapping file id2978 NCBI file | EvidenceTAS |
| GeneGUCA1ANB-GUCA1A | AuthorityHGNC:56129 | Mapping file id118142757 NCBI file | EvidenceTAS |
| GeneGUCA1B | AuthorityHGNC:4679 | Mapping file id2979 NCBI file | EvidenceTAS |
| GeneGUCA1C | AuthorityHGNC:4680 | Mapping file id9626 NCBI file | EvidenceTAS |
| GeneGUCY2D | AuthorityHGNC:4689 | Mapping file id3000 NCBI file | EvidenceTAS |
| GeneGUCY2F | AuthorityHGNC:4691 | Mapping file id2986 NCBI file | EvidenceTAS |
| GeneHSD17B1 | AuthorityHGNC:5210 | Mapping file id3292 NCBI file | EvidenceIEA |
| GeneHSD17B6 | AuthorityHGNC:23316 | Mapping file id8630 NCBI file | EvidenceTAS |
| GeneHSPG2 | AuthorityHGNC:5273 | Mapping file id3339 NCBI file | EvidenceTAS |
| GeneITPR3 | AuthorityHGNC:6182 | Mapping file id3710 NCBI file | EvidenceTAS |
| GeneKCNJ2 | AuthorityHGNC:6263 | Mapping file id3759 NCBI file | EvidenceIEA |
Evidence codes on this page: IEA, TAS, as the mapping file writes them; a row carrying two was written twice by the file, once under each. The mapping file id says which file placed the gene: an NCBI Gene id from NCBI2Reactome_All_Levels.txt, an Ensembl gene id from Ensembl2Reactome_All_Levels.txt. The two files can disagree about a code, so a row's codes are the one file's view. Measured by this site's build over this release on 2026-09-09: of the 138,908 human pathway-gene pairs both files place, 207 (0.149 per cent, over 47 genes) carry TAS in the Ensembl file where the NCBI rows carry IEA alone.
- Reactome mapping files, the human rows for this pathway · Reactome release 97 · read · Reactome downloads"NCBI2Reactome_All_Levels.txt" and "Ensembl2Reactome_All_Levels.txt", Reactome, release 97, https://reactome.org/download-data/ (date of access 2026-09-09). Data CC0; attribution encouraged.
03The hierarchy
Parents and children in this release's hierarchy
Parents
None: this is a top-level pathway of the release.
Reactome's hierarchy is a graph rather than a tree: a pathway can sit under more than one parent, and the gene counts are each pathway's own placements at every level under it, so a parent's count is not the sum of its children's.
- Reactome, the human pathway list and hierarchy relationship file · Reactome release 97 · read · Reactome downloads"ReactomePathways.txt" and "ReactomePathwaysRelation.txt", Reactome, release 97, https://reactome.org/download-data/ (date of access 2026-09-09). Data CC0; attribution encouraged.