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Pathway Human Homo sapiens

Sensory Perception

R-HSA-9709957 in Reactome release 97: a top-level pathway, with 641 genes placed in it by the mapping files and 4 child pathways in the hierarchy.

The same number in the other species

Reactome writes the mouse and rat events it infers from a human pathway under the human number with the species token. A door opens only where that species' own list in this release holds the id: R-MMU-9709957 (mouse), R-RNO-9709957 (rat). Whether the event was inferred from this one is what the record says.

01The record

Reactome's own record of this pathway

What this tells you

The pathway list, the hierarchy and the genes on this page are read from the files Reactome publishes for Reactome release 97, built into this site on 2026-09-09: the pathway list, the hierarchy relationship file and the two gene mapping files. The record card is the one live read, Reactome's own record of this pathway.

Reactome's download page describes the mapping files: Mapping files link the source database identifier to the lowest level pathway diagram or subset of the pathway, all levels of the pathway hierarchy or database identifier to all reactions. [R13] The gene list here is the all-levels mapping of NCBI Gene ids, filled from the all-levels mapping of Ensembl ids where the NCBI file has no row for a gene; each row names which file it came from by the shape of its source id. Each row carries the evidence codes the file writes for it, as written and unranked, and both where the file writes both; no page of Reactome's documentation the survey read defines the codes, so this page does not expand them. A gene id the identity files do not name is kept as the source's own id with no door rather than turned into a symbol.

On citing what a search finds, Reactome says: It should be remembered that while we strive to contain the most current and accurate data, Reactome should not be used in citations where other primary sources of information are available. [R12] The record card prints the literature Reactome attaches to a curated pathway for that reason. The data are public domain: All data in the Reactome database and files derived from that data are licensed under the Creative Commons Public Domain Dedication (CC0). User may copy, modify, and distribute these data, even for commercial purposes, without asking for permission. Attribution is encouraged but not required. [R10] The pathway illustrations are licensed apart, under CC BY 4.0, and none is shown here.

A gene on this list is one Reactome places in this pathway in this release, and that is all the row says: it does not say the gene is expressed in a tissue or associated with a disease, which are the other two explorers' questions, read from other sources. Reactome's papers of record are [R01] [R02].

  1. [R01] Ragueneau E, Gong C, Sinquin P, Sevilla C, Beavers D, Grentner A, et al. (2026). The Reactome Knowledgebase 2026. Nucleic Acids Research 54:D673-D681. PMID 41251150, doi 10.1093/nar/gkaf1223.
  2. [R02] Milacic M, Beavers D, Conley P, Gong C, Gillespie M, Griss J, et al. (2024). The Reactome Pathway Knowledgebase 2024. Nucleic Acids Research 52:D672-D678. PMID 37941124, doi 10.1093/nar/gkad1025.
  3. [R10] Reactome, reactome.org. License Agreement. https://reactome.org/license, read 2026-09-09.
  4. [R12] Reactome, reactome.org. Citing us. https://reactome.org/cite, read 2026-09-09.
  5. [R13] Reactome, reactome.org. Download. https://reactome.org/download-data, read 2026-09-09.
Reading this pathway's record from Reactome (the pathway record).Still reading. A first read of a pathway can take a while; this page waits up to 35 seconds for it, and its scripts then bring in the panel, or a line saying what did not arrive.

02The genes

Genes Reactome places in this human pathway

The mapping files place 641 genes in this human pathway; showing 1 to 100, in pages of 100, sorted by symbol for reading. The order carries no ranking.

Genes Reactome places in this human pathway, page 1 of 7
GeneABCA4AuthorityHGNC:34Mapping file id24 NCBI fileEvidenceIEA, TAS
GeneACTBAuthorityHGNC:132Mapping file id60 NCBI fileEvidenceIEA
GeneACTG1AuthorityHGNC:144Mapping file id71 NCBI fileEvidenceIEA
GeneADCY3AuthorityHGNC:234Mapping file id109 NCBI fileEvidenceIEA
GeneAGRNAuthorityHGNC:329Mapping file id375790 NCBI fileEvidenceTAS
GeneAKR1B10AuthorityHGNC:382Mapping file id57016 NCBI fileEvidenceTAS
GeneAKR1C1AuthorityHGNC:384Mapping file id1645 NCBI fileEvidenceTAS
GeneAKR1C3AuthorityHGNC:386Mapping file id8644 NCBI fileEvidenceTAS
GeneAKR1C4AuthorityHGNC:387Mapping file id1109 NCBI fileEvidenceTAS
GeneANO2AuthorityHGNC:1183Mapping file id57101 NCBI fileEvidenceIEA
GeneAPOA1AuthorityHGNC:600Mapping file id335 NCBI fileEvidenceIEA, TAS
GeneAPOA2AuthorityHGNC:601Mapping file id336 NCBI fileEvidenceIEA, TAS
GeneAPOA4AuthorityHGNC:602Mapping file id337 NCBI fileEvidenceIEA, TAS
GeneAPOBAuthorityHGNC:603Mapping file id338 NCBI fileEvidenceIEA, TAS
GeneAPOC2AuthorityHGNC:609Mapping file id344 NCBI fileEvidenceIEA, TAS
GeneAPOC3AuthorityHGNC:610Mapping file id345 NCBI fileEvidenceIEA, TAS
GeneAPOEAuthorityHGNC:613Mapping file id348 NCBI fileEvidenceIEA, TAS
GeneAPOMAuthorityHGNC:13916Mapping file id55937 NCBI fileEvidenceTAS
GeneATP2B1AuthorityHGNC:814Mapping file id490 NCBI fileEvidenceIEA
GeneATP2B2AuthorityHGNC:815Mapping file id491 NCBI fileEvidenceIEA
GeneAWAT2AuthorityHGNC:23251Mapping file id158835 NCBI fileEvidenceTAS
GeneBCO1AuthorityHGNC:13815Mapping file id53630 NCBI fileEvidenceTAS
GeneBCO2AuthorityHGNC:18503Mapping file id83875 NCBI fileEvidenceTAS
GeneBSNAuthorityHGNC:1117Mapping file id8927 NCBI fileEvidenceIEA
GeneCABP1AuthorityHGNC:1384Mapping file id9478 NCBI fileEvidenceIEA
GeneCABP2AuthorityHGNC:1385Mapping file id51475 NCBI fileEvidenceIEA
GeneCACNA1DAuthorityHGNC:1391Mapping file id776 NCBI fileEvidenceIEA
GeneCACNA2D2AuthorityHGNC:1400Mapping file id9254 NCBI fileEvidenceIEA
GeneCACNB2AuthorityHGNC:1402Mapping file id783 NCBI fileEvidenceIEA
GeneCALHM1AuthorityHGNC:23494Mapping file id255022 NCBI fileEvidenceIEA
GeneCALHM3AuthorityHGNC:23458Mapping file id119395 NCBI fileEvidenceIEA
GeneCALM1AuthorityHGNC:1442Mapping file id801 NCBI fileEvidenceIEA, TAS
GeneCALM2AuthorityHGNC:1445Mapping file id805 NCBI fileEvidenceIEA, TAS
GeneCALM3AuthorityHGNC:1449Mapping file id808 NCBI fileEvidenceIEA, TAS
GeneCAMKMTAuthorityHGNC:26276Mapping file id79823 NCBI fileEvidenceTAS
GeneCAPZA1AuthorityHGNC:1488Mapping file id829 NCBI fileEvidenceIEA
GeneCAPZA2AuthorityHGNC:1490Mapping file id830 NCBI fileEvidenceIEA
GeneCAPZBAuthorityHGNC:1491Mapping file id832 NCBI fileEvidenceIEA
GeneCASKAuthorityHGNC:1497Mapping file id8573 NCBI fileEvidenceIEA
GeneCDH23AuthorityHGNC:13733Mapping file id64072 NCBI fileEvidenceIEA
GeneCHRNA10AuthorityHGNC:13800Mapping file id57053 NCBI fileEvidenceIEA
GeneCHRNA9AuthorityHGNC:14079Mapping file id55584 NCBI fileEvidenceIEA
GeneCHURC1-FNTBAuthorityHGNC:42960Mapping file id100529261 NCBI fileEvidenceTAS
GeneCIB2AuthorityHGNC:24579Mapping file id10518 NCBI fileEvidenceIEA
GeneCLIC5AuthorityHGNC:13517Mapping file id53405 NCBI fileEvidenceIEA
GeneCLPSAuthorityHGNC:2085Mapping file id1208 NCBI fileEvidenceTAS
GeneCNGA1AuthorityHGNC:2148Mapping file id1259 NCBI fileEvidenceTAS
GeneCNGA2AuthorityHGNC:2149Mapping file id1260 NCBI fileEvidenceIEA
GeneCNGA4AuthorityHGNC:2152Mapping file id1262 NCBI fileEvidenceIEA
GeneCNGB1AuthorityHGNC:2151Mapping file id1258 NCBI fileEvidenceIEA, TAS
GeneCTBP2AuthorityHGNC:2495Mapping file id1488 NCBI fileEvidenceIEA
GeneCYP4V2AuthorityHGNC:23198Mapping file id285440 NCBI fileEvidenceTAS
GeneDHRS3AuthorityHGNC:17693Mapping file id9249 NCBI fileEvidenceTAS
GeneDHRS9AuthorityHGNC:16888Mapping file id10170 NCBI fileEvidenceTAS
GeneDNAJC5AuthorityHGNC:16235Mapping file id80331 NCBI fileEvidenceIEA
GeneEBF1AuthorityHGNC:3126Mapping file id1879 NCBI fileEvidenceIEA
GeneEPB41L1AuthorityHGNC:3378Mapping file id2036 NCBI fileEvidenceIEA
GeneEPB41L3AuthorityHGNC:3380Mapping file id23136 NCBI fileEvidenceIEA
GeneEPS8AuthorityHGNC:3420Mapping file id2059 NCBI fileEvidenceIEA
GeneEPS8L2AuthorityHGNC:21296Mapping file id64787 NCBI fileEvidenceIEA
GeneESPNAuthorityHGNC:13281Mapping file id83715 NCBI fileEvidenceIEA
GeneESPNLAuthorityHGNC:27937Mapping file id339768 NCBI fileEvidenceIEA
GeneEZRAuthorityHGNC:12691Mapping file id7430 NCBI fileEvidenceIEA
GeneFNTAAuthorityHGNC:3782Mapping file id2339 NCBI fileEvidenceTAS
GeneFNTBAuthorityHGNC:3785Mapping file id2342 NCBI fileEvidenceTAS
GeneFSCN2AuthorityHGNC:3960Mapping file id25794 NCBI fileEvidenceIEA
GeneGNALAuthorityHGNC:4388Mapping file id2774 NCBI fileEvidenceIEA, TAS
GeneGNAT1AuthorityHGNC:4393Mapping file id2779 NCBI fileEvidenceIEA, TAS
GeneGNAT3AuthorityHGNC:22800Mapping file id346562 NCBI fileEvidenceIEA, TAS
GeneGNB1AuthorityHGNC:4396Mapping file id2782 NCBI fileEvidenceIEA, TAS
GeneGNB3AuthorityHGNC:4400Mapping file id2784 NCBI fileEvidenceIEA, TAS
GeneGNB5AuthorityHGNC:4401Mapping file id10681 NCBI fileEvidenceIEA, TAS
GeneGNG13AuthorityHGNC:14131Mapping file id51764 NCBI fileEvidenceIEA, TAS
GeneGNGT1AuthorityHGNC:4411Mapping file id2792 NCBI fileEvidenceIEA, TAS
GeneGPC1AuthorityHGNC:4449Mapping file id2817 NCBI fileEvidenceTAS
GeneGPC2AuthorityHGNC:4450Mapping file id221914 NCBI fileEvidenceTAS
GeneGPC3AuthorityHGNC:4451Mapping file id2719 NCBI fileEvidenceTAS
GeneGPC4AuthorityHGNC:4452Mapping file id2239 NCBI fileEvidenceTAS
GeneGPC5AuthorityHGNC:4453Mapping file id2262 NCBI fileEvidenceTAS
GeneGPC6AuthorityHGNC:4454Mapping file id10082 NCBI fileEvidenceTAS
GeneGPIHBP1AuthorityHGNC:24945Mapping file id338328 NCBI fileEvidenceTAS
GeneGRK1AuthorityHGNC:10013Mapping file id6011 NCBI fileEvidenceIEA, TAS
GeneGRK4AuthorityHGNC:4543Mapping file id2868 NCBI fileEvidenceTAS
GeneGRK7AuthorityHGNC:17031Mapping file id131890 NCBI fileEvidenceTAS
GeneGRM1AuthorityHGNC:4593Mapping file id2911 NCBI fileEvidenceIEA
GeneGRM4AuthorityHGNC:4596Mapping file id2914 NCBI fileEvidenceIEA
GeneGRXCR1AuthorityHGNC:31673Mapping file id389207 NCBI fileEvidenceIEA
GeneGRXCR2AuthorityHGNC:33862Mapping file id643226 NCBI fileEvidenceIEA
GeneGSNAuthorityHGNC:4620Mapping file id2934 NCBI fileEvidenceIEA
GeneGUCA1AAuthorityHGNC:4678Mapping file id2978 NCBI fileEvidenceTAS
GeneGUCA1ANB-GUCA1AAuthorityHGNC:56129Mapping file id118142757 NCBI fileEvidenceTAS
GeneGUCA1BAuthorityHGNC:4679Mapping file id2979 NCBI fileEvidenceTAS
GeneGUCA1CAuthorityHGNC:4680Mapping file id9626 NCBI fileEvidenceTAS
GeneGUCY2DAuthorityHGNC:4689Mapping file id3000 NCBI fileEvidenceTAS
GeneGUCY2FAuthorityHGNC:4691Mapping file id2986 NCBI fileEvidenceTAS
GeneHSD17B1AuthorityHGNC:5210Mapping file id3292 NCBI fileEvidenceIEA
GeneHSD17B6AuthorityHGNC:23316Mapping file id8630 NCBI fileEvidenceTAS
GeneHSPG2AuthorityHGNC:5273Mapping file id3339 NCBI fileEvidenceTAS
GeneITPR3AuthorityHGNC:6182Mapping file id3710 NCBI fileEvidenceTAS
GeneKCNJ2AuthorityHGNC:6263Mapping file id3759 NCBI fileEvidenceIEA

Evidence codes on this page: IEA, TAS, as the mapping file writes them; a row carrying two was written twice by the file, once under each. The mapping file id says which file placed the gene: an NCBI Gene id from NCBI2Reactome_All_Levels.txt, an Ensembl gene id from Ensembl2Reactome_All_Levels.txt. The two files can disagree about a code, so a row's codes are the one file's view. Measured by this site's build over this release on 2026-09-09: of the 138,908 human pathway-gene pairs both files place, 207 (0.149 per cent, over 47 genes) carry TAS in the Ensembl file where the NCBI rows carry IEA alone.

  • Reactome mapping files, the human rows for this pathway · Reactome release 97 · read · Reactome downloads"NCBI2Reactome_All_Levels.txt" and "Ensembl2Reactome_All_Levels.txt", Reactome, release 97, https://reactome.org/download-data/ (date of access 2026-09-09). Data CC0; attribution encouraged.

03The hierarchy

Parents and children in this release's hierarchy

Reactome's hierarchy is a graph rather than a tree: a pathway can sit under more than one parent, and the gene counts are each pathway's own placements at every level under it, so a parent's count is not the sum of its children's.

  • Reactome, the human pathway list and hierarchy relationship file · Reactome release 97 · read · Reactome downloads"ReactomePathways.txt" and "ReactomePathwaysRelation.txt", Reactome, release 97, https://reactome.org/download-data/ (date of access 2026-09-09). Data CC0; attribution encouraged.