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Pathway Human Homo sapiens

Cilium Assembly

R-HSA-5617833 in Reactome release 97: under Organelle biogenesis and maintenance, with 233 genes placed in it by the mapping files and 2 child pathways in the hierarchy.

The same number in the other species

Reactome writes the mouse and rat events it infers from a human pathway under the human number with the species token. A door opens only where that species' own list in this release holds the id: R-MMU-5617833 (mouse), R-RNO-5617833 (rat). Whether the event was inferred from this one is what the record says.

01The record

Reactome's own record of this pathway

What this tells you

The pathway list, the hierarchy and the genes on this page are read from the files Reactome publishes for Reactome release 97, built into this site on 2026-09-09: the pathway list, the hierarchy relationship file and the two gene mapping files. The record card is the one live read, Reactome's own record of this pathway.

Reactome's download page describes the mapping files: Mapping files link the source database identifier to the lowest level pathway diagram or subset of the pathway, all levels of the pathway hierarchy or database identifier to all reactions. [R13] The gene list here is the all-levels mapping of NCBI Gene ids, filled from the all-levels mapping of Ensembl ids where the NCBI file has no row for a gene; each row names which file it came from by the shape of its source id. Each row carries the evidence codes the file writes for it, as written and unranked, and both where the file writes both; no page of Reactome's documentation the survey read defines the codes, so this page does not expand them. A gene id the identity files do not name is kept as the source's own id with no door rather than turned into a symbol.

On citing what a search finds, Reactome says: It should be remembered that while we strive to contain the most current and accurate data, Reactome should not be used in citations where other primary sources of information are available. [R12] The record card prints the literature Reactome attaches to a curated pathway for that reason. The data are public domain: All data in the Reactome database and files derived from that data are licensed under the Creative Commons Public Domain Dedication (CC0). User may copy, modify, and distribute these data, even for commercial purposes, without asking for permission. Attribution is encouraged but not required. [R10] The pathway illustrations are licensed apart, under CC BY 4.0, and none is shown here.

A gene on this list is one Reactome places in this pathway in this release, and that is all the row says: it does not say the gene is expressed in a tissue or associated with a disease, which are the other two explorers' questions, read from other sources. Reactome's papers of record are [R01] [R02].

  1. [R01] Ragueneau E, Gong C, Sinquin P, Sevilla C, Beavers D, Grentner A, et al. (2026). The Reactome Knowledgebase 2026. Nucleic Acids Research 54:D673-D681. PMID 41251150, doi 10.1093/nar/gkaf1223.
  2. [R02] Milacic M, Beavers D, Conley P, Gong C, Gillespie M, Griss J, et al. (2024). The Reactome Pathway Knowledgebase 2024. Nucleic Acids Research 52:D672-D678. PMID 37941124, doi 10.1093/nar/gkad1025.
  3. [R10] Reactome, reactome.org. License Agreement. https://reactome.org/license, read 2026-09-09.
  4. [R12] Reactome, reactome.org. Citing us. https://reactome.org/cite, read 2026-09-09.
  5. [R13] Reactome, reactome.org. Download. https://reactome.org/download-data, read 2026-09-09.
Reading this pathway's record from Reactome (the pathway record).Still reading. A first read of a pathway can take a while; this page waits up to 35 seconds for it, and its scripts then bring in the panel, or a line saying what did not arrive.

02The genes

Genes Reactome places in this human pathway

The mapping files place 233 genes in this human pathway; showing 1 to 100, in pages of 100, sorted by symbol for reading. The order carries no ranking.

Genes Reactome places in this human pathway, page 1 of 3
GeneACTR1AAuthorityHGNC:167Mapping file id10121 NCBI fileEvidenceTAS
GeneAGO1AuthorityHGNC:3262Mapping file id26523 NCBI fileEvidenceTAS
GeneAGO2AuthorityHGNC:3263Mapping file id27161 NCBI fileEvidenceTAS
GeneAGO3AuthorityHGNC:18421Mapping file id192669 NCBI fileEvidenceTAS
GeneAGO4AuthorityHGNC:18424Mapping file id192670 NCBI fileEvidenceTAS
GeneAHI1AuthorityHGNC:21575Mapping file id54806 NCBI fileEvidenceTAS
GeneAKAP9AuthorityHGNC:379Mapping file id10142 NCBI fileEvidenceTAS
GeneALMS1AuthorityHGNC:428Mapping file id7840 NCBI fileEvidenceTAS
GeneARF4AuthorityHGNC:655Mapping file id378 NCBI fileEvidenceIEA, TAS
GeneARL13BAuthorityHGNC:25419Mapping file id200894 NCBI fileEvidenceTAS
GeneARL3AuthorityHGNC:694Mapping file id403 NCBI fileEvidenceTAS
GeneARL6AuthorityHGNC:13210Mapping file id84100 NCBI fileEvidenceTAS
GeneASAP1AuthorityHGNC:2720Mapping file id50807 NCBI fileEvidenceIEA, TAS
GeneATAT1AuthorityHGNC:21186Mapping file id79969 NCBI fileEvidenceTAS
GeneB9D1AuthorityHGNC:24123Mapping file id27077 NCBI fileEvidenceTAS
GeneB9D2AuthorityHGNC:28636Mapping file id80776 NCBI fileEvidenceTAS
GeneBBIP1AuthorityHGNC:28093Mapping file id92482 NCBI fileEvidenceTAS
GeneBBS1AuthorityHGNC:966Mapping file id582 NCBI fileEvidenceTAS
GeneBBS10AuthorityHGNC:26291Mapping file id79738 NCBI fileEvidenceTAS
GeneBBS12AuthorityHGNC:26648Mapping file id166379 NCBI fileEvidenceTAS
GeneBBS2AuthorityHGNC:967Mapping file id583 NCBI fileEvidenceTAS
GeneBBS4AuthorityHGNC:969Mapping file id585 NCBI fileEvidenceTAS
GeneBBS5AuthorityHGNC:970Mapping file id129880 NCBI fileEvidenceTAS
GeneBBS7AuthorityHGNC:18758Mapping file id55212 NCBI fileEvidenceTAS
GeneBBS9AuthorityHGNC:30000Mapping file id27241 NCBI fileEvidenceTAS
GeneC2CD3AuthorityHGNC:24564Mapping file id26005 NCBI fileEvidenceTAS
GeneCC2D2AAuthorityHGNC:29253Mapping file id57545 NCBI fileEvidenceTAS
GeneCCDC78AuthorityHGNC:14153Mapping file idENSG00000162004 Ensembl fileEvidenceTAS
GeneCCNOAuthorityHGNC:18576Mapping file id10309 NCBI fileEvidenceTAS
GeneCCP110AuthorityHGNC:24342Mapping file id9738 NCBI fileEvidenceTAS
GeneCCT2AuthorityHGNC:1615Mapping file id10576 NCBI fileEvidenceTAS
GeneCCT3AuthorityHGNC:1616Mapping file id7203 NCBI fileEvidenceTAS
GeneCCT4AuthorityHGNC:1617Mapping file id10575 NCBI fileEvidenceTAS
GeneCCT5AuthorityHGNC:1618Mapping file id22948 NCBI fileEvidenceTAS
GeneCCT8AuthorityHGNC:1623Mapping file id10694 NCBI fileEvidenceTAS
GeneCDK1AuthorityHGNC:1722Mapping file id983 NCBI fileEvidenceTAS
GeneCDK5RAP2AuthorityHGNC:18672Mapping file id55755 NCBI fileEvidenceTAS
GeneCEP131AuthorityHGNC:29511Mapping file id22994 NCBI fileEvidenceTAS
GeneCEP135AuthorityHGNC:29086Mapping file id9662 NCBI fileEvidenceTAS
GeneCEP152AuthorityHGNC:29298Mapping file id22995 NCBI fileEvidenceTAS
GeneCEP162AuthorityHGNC:21107Mapping file id22832 NCBI fileEvidenceTAS
GeneCEP164AuthorityHGNC:29182Mapping file id22897 NCBI fileEvidenceTAS
GeneCEP192AuthorityHGNC:25515Mapping file id55125 NCBI fileEvidenceTAS
GeneCEP250AuthorityHGNC:1859Mapping file id11190 NCBI fileEvidenceTAS
GeneCEP290AuthorityHGNC:29021Mapping file id80184 NCBI fileEvidenceTAS
GeneCEP41AuthorityHGNC:12370Mapping file id95681 NCBI fileEvidenceTAS
GeneCEP43AuthorityHGNC:17012Mapping file id11116 NCBI fileEvidenceTAS
GeneCEP57AuthorityHGNC:30794Mapping file id9702 NCBI fileEvidenceTAS
GeneCEP63AuthorityHGNC:25815Mapping file id80254 NCBI fileEvidenceTAS
GeneCEP70AuthorityHGNC:29972Mapping file id80321 NCBI fileEvidenceTAS
GeneCEP72AuthorityHGNC:25547Mapping file id55722 NCBI fileEvidenceTAS
GeneCEP76AuthorityHGNC:25727Mapping file id79959 NCBI fileEvidenceTAS
GeneCEP78AuthorityHGNC:25740Mapping file id84131 NCBI fileEvidenceTAS
GeneCEP83AuthorityHGNC:17966Mapping file id51134 NCBI fileEvidenceTAS
GeneCEP89AuthorityHGNC:25907Mapping file id84902 NCBI fileEvidenceTAS
GeneCEP97AuthorityHGNC:26244Mapping file id79598 NCBI fileEvidenceTAS
GeneCETN2AuthorityHGNC:1867Mapping file id1069 NCBI fileEvidenceTAS
GeneCKAP5AuthorityHGNC:28959Mapping file id9793 NCBI fileEvidenceTAS
GeneCLASP1AuthorityHGNC:17088Mapping file id23332 NCBI fileEvidenceTAS
GeneCNGA2AuthorityHGNC:2149Mapping file id1260 NCBI fileEvidenceIEA, TAS
GeneCNGA4AuthorityHGNC:2152Mapping file id1262 NCBI fileEvidenceIEA, TAS
GeneCNGB1AuthorityHGNC:2151Mapping file id1258 NCBI fileEvidenceIEA, TAS
GeneCNTRLAuthorityHGNC:1858Mapping file id11064 NCBI fileEvidenceTAS
GeneCPAPAuthorityHGNC:17272Mapping file id55835 NCBI fileEvidenceTAS
GeneCSNK1DAuthorityHGNC:2452Mapping file id1453 NCBI fileEvidenceTAS
GeneCSNK1EAuthorityHGNC:2453Mapping file id1454 NCBI fileEvidenceTAS
GeneCYS1AuthorityHGNC:18525Mapping file id192668 NCBI fileEvidenceTAS
GeneDCTN1AuthorityHGNC:2711Mapping file id1639 NCBI fileEvidenceTAS
GeneDCTN2AuthorityHGNC:2712Mapping file id10540 NCBI fileEvidenceTAS
GeneDCTN3AuthorityHGNC:2713Mapping file id11258 NCBI fileEvidenceTAS
GeneDEUP1AuthorityHGNC:26344Mapping file id159989 NCBI fileEvidenceTAS
GeneDLL1AuthorityHGNC:2908Mapping file id28514 NCBI fileEvidenceTAS
GeneDYNC1H1AuthorityHGNC:2961Mapping file id1778 NCBI fileEvidenceTAS
GeneDYNC1I2AuthorityHGNC:2964Mapping file id1781 NCBI fileEvidenceTAS
GeneDYNC2H1AuthorityHGNC:2962Mapping file id79659 NCBI fileEvidenceTAS
GeneDYNC2I1AuthorityHGNC:21862Mapping file id55112 NCBI fileEvidenceTAS
GeneDYNC2I2AuthorityHGNC:28296Mapping file id89891 NCBI fileEvidenceTAS
GeneDYNC2LI1AuthorityHGNC:24595Mapping file id51626 NCBI fileEvidenceTAS
GeneDYNLL1AuthorityHGNC:15476Mapping file id8655 NCBI fileEvidenceTAS
GeneDYNLL2AuthorityHGNC:24596Mapping file id140735 NCBI fileEvidenceTAS
GeneDYNLRB1AuthorityHGNC:15468Mapping file id83658 NCBI fileEvidenceTAS
GeneDYNLRB2AuthorityHGNC:15467Mapping file id83657 NCBI fileEvidenceTAS
GeneDYNLT2AuthorityHGNC:11695Mapping file id6991 NCBI fileEvidenceTAS
GeneDYNLT2BAuthorityHGNC:28482Mapping file id255758 NCBI fileEvidenceTAS
GeneDYNLT5AuthorityHGNC:26882Mapping file id200132 NCBI fileEvidenceTAS
GeneE2F4AuthorityHGNC:3118Mapping file id1874 NCBI fileEvidenceIEA, TAS
GeneE2F5AuthorityHGNC:3119Mapping file id1875 NCBI fileEvidenceIEA, TAS
GeneEXOC1AuthorityHGNC:30380Mapping file id55763 NCBI fileEvidenceTAS
GeneEXOC2AuthorityHGNC:24968Mapping file id55770 NCBI fileEvidenceTAS
GeneEXOC3AuthorityHGNC:30378Mapping file id11336 NCBI fileEvidenceTAS
GeneEXOC4AuthorityHGNC:30389Mapping file id60412 NCBI fileEvidenceTAS
GeneEXOC5AuthorityHGNC:10696Mapping file id10640 NCBI fileEvidenceTAS
GeneEXOC6AuthorityHGNC:23196Mapping file id54536 NCBI fileEvidenceTAS
GeneEXOC7AuthorityHGNC:23214Mapping file id23265 NCBI fileEvidenceTAS
GeneEXOC8AuthorityHGNC:24659Mapping file id149371 NCBI fileEvidenceTAS
GeneFBF1AuthorityHGNC:24674Mapping file id85302 NCBI fileEvidenceTAS
GeneFOXJ1AuthorityHGNC:3816Mapping file id2302 NCBI fileEvidenceTAS
GeneGBF1AuthorityHGNC:4181Mapping file id8729 NCBI fileEvidenceTAS
GeneGMNCAuthorityHGNC:40049Mapping file id647309 NCBI fileEvidenceTAS
GeneGMNNAuthorityHGNC:17493Mapping file id51053 NCBI fileEvidenceTAS

Evidence codes on this page: IEA, TAS, as the mapping file writes them; a row carrying two was written twice by the file, once under each. The mapping file id says which file placed the gene: an NCBI Gene id from NCBI2Reactome_All_Levels.txt, an Ensembl gene id from Ensembl2Reactome_All_Levels.txt. The two files can disagree about a code, so a row's codes are the one file's view. Measured by this site's build over this release on 2026-09-09: of the 138,908 human pathway-gene pairs both files place, 207 (0.149 per cent, over 47 genes) carry TAS in the Ensembl file where the NCBI rows carry IEA alone.

  • Reactome mapping files, the human rows for this pathway · Reactome release 97 · read · Reactome downloads"NCBI2Reactome_All_Levels.txt" and "Ensembl2Reactome_All_Levels.txt", Reactome, release 97, https://reactome.org/download-data/ (date of access 2026-09-09). Data CC0; attribution encouraged.

03The hierarchy

Parents and children in this release's hierarchy

Reactome's hierarchy is a graph rather than a tree: a pathway can sit under more than one parent, and the gene counts are each pathway's own placements at every level under it, so a parent's count is not the sum of its children's.

  • Reactome, the human pathway list and hierarchy relationship file · Reactome release 97 · read · Reactome downloads"ReactomePathways.txt" and "ReactomePathwaysRelation.txt", Reactome, release 97, https://reactome.org/download-data/ (date of access 2026-09-09). Data CC0; attribution encouraged.