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Pathway Human Homo sapiens

Mitotic Anaphase

R-HSA-68882 in Reactome release 97: under Mitotic Metaphase and Anaphase, with 225 genes placed in it by the mapping files and 2 child pathways in the hierarchy.

The same number in the other species

Reactome writes the mouse and rat events it infers from a human pathway under the human number with the species token. A door opens only where that species' own list in this release holds the id: R-MMU-68882 (mouse), R-RNO-68882 (rat). Whether the event was inferred from this one is what the record says.

01The record

Reactome's own record of this pathway

What this tells you

The pathway list, the hierarchy and the genes on this page are read from the files Reactome publishes for Reactome release 97, built into this site on 2026-09-09: the pathway list, the hierarchy relationship file and the two gene mapping files. The record card is the one live read, Reactome's own record of this pathway.

Reactome's download page describes the mapping files: Mapping files link the source database identifier to the lowest level pathway diagram or subset of the pathway, all levels of the pathway hierarchy or database identifier to all reactions. [R13] The gene list here is the all-levels mapping of NCBI Gene ids, filled from the all-levels mapping of Ensembl ids where the NCBI file has no row for a gene; each row names which file it came from by the shape of its source id. Each row carries the evidence codes the file writes for it, as written and unranked, and both where the file writes both; no page of Reactome's documentation the survey read defines the codes, so this page does not expand them. A gene id the identity files do not name is kept as the source's own id with no door rather than turned into a symbol.

On citing what a search finds, Reactome says: It should be remembered that while we strive to contain the most current and accurate data, Reactome should not be used in citations where other primary sources of information are available. [R12] The record card prints the literature Reactome attaches to a curated pathway for that reason. The data are public domain: All data in the Reactome database and files derived from that data are licensed under the Creative Commons Public Domain Dedication (CC0). User may copy, modify, and distribute these data, even for commercial purposes, without asking for permission. Attribution is encouraged but not required. [R10] The pathway illustrations are licensed apart, under CC BY 4.0, and none is shown here.

A gene on this list is one Reactome places in this pathway in this release, and that is all the row says: it does not say the gene is expressed in a tissue or associated with a disease, which are the other two explorers' questions, read from other sources. Reactome's papers of record are [R01] [R02].

  1. [R01] Ragueneau E, Gong C, Sinquin P, Sevilla C, Beavers D, Grentner A, et al. (2026). The Reactome Knowledgebase 2026. Nucleic Acids Research 54:D673-D681. PMID 41251150, doi 10.1093/nar/gkaf1223.
  2. [R02] Milacic M, Beavers D, Conley P, Gong C, Gillespie M, Griss J, et al. (2024). The Reactome Pathway Knowledgebase 2024. Nucleic Acids Research 52:D672-D678. PMID 37941124, doi 10.1093/nar/gkad1025.
  3. [R10] Reactome, reactome.org. License Agreement. https://reactome.org/license, read 2026-09-09.
  4. [R12] Reactome, reactome.org. Citing us. https://reactome.org/cite, read 2026-09-09.
  5. [R13] Reactome, reactome.org. Download. https://reactome.org/download-data, read 2026-09-09.
Reading this pathway's record from Reactome (the pathway record).Still reading. A first read of a pathway can take a while; this page waits up to 35 seconds for it, and its scripts then bring in the panel, or a line saying what did not arrive.

02The genes

Genes Reactome places in this human pathway

The mapping files place 225 genes in this human pathway; showing 1 to 100, in pages of 100, sorted by symbol for reading. The order carries no ranking.

Genes Reactome places in this human pathway, page 1 of 3
GeneADRM1AuthorityHGNC:15759Mapping file id11047 NCBI fileEvidenceTAS
GeneAHCTF1AuthorityHGNC:24618Mapping file id25909 NCBI fileEvidenceIEA, TAS
GeneANAPC1AuthorityHGNC:19988Mapping file id64682 NCBI fileEvidenceTAS
GeneANAPC10AuthorityHGNC:24077Mapping file id10393 NCBI fileEvidenceTAS
GeneANAPC11AuthorityHGNC:14452Mapping file id51529 NCBI fileEvidenceTAS
GeneANAPC15AuthorityHGNC:24531Mapping file id25906 NCBI fileEvidenceTAS
GeneANAPC16AuthorityHGNC:26976Mapping file id119504 NCBI fileEvidenceTAS
GeneANAPC2AuthorityHGNC:19989Mapping file id29882 NCBI fileEvidenceTAS
GeneANAPC4AuthorityHGNC:19990Mapping file id29945 NCBI fileEvidenceTAS
GeneANAPC5AuthorityHGNC:15713Mapping file id51433 NCBI fileEvidenceTAS
GeneANAPC7AuthorityHGNC:17380Mapping file id51434 NCBI fileEvidenceTAS
GeneANKLE2AuthorityHGNC:29101Mapping file id23141 NCBI fileEvidenceTAS
GeneAURKBAuthorityHGNC:11390Mapping file id9212 NCBI fileEvidenceTAS
GeneB9D2AuthorityHGNC:28636Mapping file id80776 NCBI fileEvidenceTAS
GeneBANF1AuthorityHGNC:17397Mapping file id8815 NCBI fileEvidenceTAS
GeneBIRC5AuthorityHGNC:593Mapping file id332 NCBI fileEvidenceTAS
GeneBUB1AuthorityHGNC:1148Mapping file id699 NCBI fileEvidenceTAS
GeneBUB1BAuthorityHGNC:1149Mapping file id701 NCBI fileEvidenceTAS
GeneBUB3AuthorityHGNC:1151Mapping file id9184 NCBI fileEvidenceTAS
GeneCC2D1BAuthorityHGNC:29386Mapping file id200014 NCBI fileEvidenceTAS
GeneCCNB1AuthorityHGNC:1579Mapping file id891 NCBI fileEvidenceTAS
GeneCCNB2AuthorityHGNC:1580Mapping file id9133 NCBI fileEvidenceTAS
GeneCDC16AuthorityHGNC:1720Mapping file id8881 NCBI fileEvidenceTAS
GeneCDC20AuthorityHGNC:1723Mapping file id991 NCBI fileEvidenceTAS
GeneCDC23AuthorityHGNC:1724Mapping file id8697 NCBI fileEvidenceTAS
GeneCDC26AuthorityHGNC:17839Mapping file id246184 NCBI fileEvidenceTAS
GeneCDC27AuthorityHGNC:1728Mapping file id996 NCBI fileEvidenceTAS
GeneCDCA5AuthorityHGNC:14626Mapping file id113130 NCBI fileEvidenceTAS
GeneCDCA8AuthorityHGNC:14629Mapping file id55143 NCBI fileEvidenceTAS
GeneCDK1AuthorityHGNC:1722Mapping file id983 NCBI fileEvidenceTAS
GeneCENPAAuthorityHGNC:1851Mapping file id1058 NCBI fileEvidenceTAS
GeneCENPCAuthorityHGNC:1854Mapping file id1060 NCBI fileEvidenceTAS
GeneCENPEAuthorityHGNC:1856Mapping file id1062 NCBI fileEvidenceTAS
GeneCENPFAuthorityHGNC:1857Mapping file id1063 NCBI fileEvidenceTAS
GeneCENPHAuthorityHGNC:17268Mapping file id64946 NCBI fileEvidenceTAS
GeneCENPIAuthorityHGNC:3968Mapping file id2491 NCBI fileEvidenceTAS
GeneCENPKAuthorityHGNC:29479Mapping file id64105 NCBI fileEvidenceTAS
GeneCENPLAuthorityHGNC:17879Mapping file id91687 NCBI fileEvidenceTAS
GeneCENPMAuthorityHGNC:18352Mapping file id79019 NCBI fileEvidenceTAS
GeneCENPNAuthorityHGNC:30873Mapping file id55839 NCBI fileEvidenceTAS
GeneCENPOAuthorityHGNC:28152Mapping file id79172 NCBI fileEvidenceTAS
GeneCENPPAuthorityHGNC:32933Mapping file id401541 NCBI fileEvidenceTAS
GeneCENPQAuthorityHGNC:21347Mapping file id55166 NCBI fileEvidenceTAS
GeneCENPSAuthorityHGNC:23163Mapping file id378708 NCBI fileEvidenceTAS
GeneCENPS-CORTAuthorityHGNC:38843Mapping file id100526739 NCBI fileEvidenceTAS
GeneCENPTAuthorityHGNC:25787Mapping file id80152 NCBI fileEvidenceTAS
GeneCENPUAuthorityHGNC:21348Mapping file id79682 NCBI fileEvidenceTAS
GeneCHMP2AAuthorityHGNC:30216Mapping file id27243 NCBI fileEvidenceTAS
GeneCHMP2BAuthorityHGNC:24537Mapping file id25978 NCBI fileEvidenceTAS
GeneCHMP3AuthorityHGNC:29865Mapping file id51652 NCBI fileEvidenceTAS
GeneCHMP4AAuthorityHGNC:20274Mapping file id29082 NCBI fileEvidenceTAS
GeneCHMP4BAuthorityHGNC:16171Mapping file id128866 NCBI fileEvidenceTAS
GeneCHMP4CAuthorityHGNC:30599Mapping file id92421 NCBI fileEvidenceTAS
GeneCHMP6AuthorityHGNC:25675Mapping file id79643 NCBI fileEvidenceTAS
GeneCHMP7AuthorityHGNC:28439Mapping file id91782 NCBI fileEvidenceTAS
GeneCKAP5AuthorityHGNC:28959Mapping file id9793 NCBI fileEvidenceTAS
GeneCLASP1AuthorityHGNC:17088Mapping file id23332 NCBI fileEvidenceTAS
GeneCLASP2AuthorityHGNC:17078Mapping file id23122 NCBI fileEvidenceTAS
GeneCLIP1AuthorityHGNC:10461Mapping file id6249 NCBI fileEvidenceTAS
GeneDSN1AuthorityHGNC:16165Mapping file id79980 NCBI fileEvidenceTAS
GeneDYNC1H1AuthorityHGNC:2961Mapping file id1778 NCBI fileEvidenceTAS
GeneDYNC1I1AuthorityHGNC:2963Mapping file id1780 NCBI fileEvidenceTAS
GeneDYNC1I2AuthorityHGNC:2964Mapping file id1781 NCBI fileEvidenceTAS
GeneDYNC1LI1AuthorityHGNC:18745Mapping file id51143 NCBI fileEvidenceTAS
GeneDYNC1LI2AuthorityHGNC:2966Mapping file id1783 NCBI fileEvidenceTAS
GeneDYNLL1AuthorityHGNC:15476Mapping file id8655 NCBI fileEvidenceTAS
GeneDYNLL2AuthorityHGNC:24596Mapping file id140735 NCBI fileEvidenceTAS
GeneEMDAuthorityHGNC:3331Mapping file id2010 NCBI fileEvidenceTAS
GeneERCC6LAuthorityHGNC:20794Mapping file id54821 NCBI fileEvidenceTAS
GeneESPL1AuthorityHGNC:16856Mapping file id9700 NCBI fileEvidenceTAS
GeneHDAC8AuthorityHGNC:13315Mapping file id55869 NCBI fileEvidenceTAS
GeneINCENPAuthorityHGNC:6058Mapping file id3619 NCBI fileEvidenceTAS
GeneIST1AuthorityHGNC:28977Mapping file id9798 NCBI fileEvidenceTAS
GeneITGB3BPAuthorityHGNC:6157Mapping file id23421 NCBI fileEvidenceTAS
GeneKIF18AAuthorityHGNC:29441Mapping file id81930 NCBI fileEvidenceTAS
GeneKIF2AAuthorityHGNC:6318Mapping file id3796 NCBI fileEvidenceTAS
GeneKIF2BAuthorityHGNC:29443Mapping file id84643 NCBI fileEvidenceTAS
GeneKIF2CAuthorityHGNC:6393Mapping file id11004 NCBI fileEvidenceTAS
GeneKNL1AuthorityHGNC:24054Mapping file id57082 NCBI fileEvidenceTAS
GeneKNTC1AuthorityHGNC:17255Mapping file id9735 NCBI fileEvidenceTAS
GeneKPNB1AuthorityHGNC:6400Mapping file id3837 NCBI fileEvidenceIEA, TAS
GeneLBRAuthorityHGNC:6518Mapping file id3930 NCBI fileEvidenceTAS
GeneLEMD2AuthorityHGNC:21244Mapping file id221496 NCBI fileEvidenceTAS
GeneLEMD3AuthorityHGNC:28887Mapping file id23592 NCBI fileEvidenceTAS
GeneLMNAAuthorityHGNC:6636Mapping file id4000 NCBI fileEvidenceTAS
GeneLMNB1AuthorityHGNC:6637Mapping file id4001 NCBI fileEvidenceTAS
GeneMAD1L1AuthorityHGNC:6762Mapping file id8379 NCBI fileEvidenceTAS
GeneMAD2L1AuthorityHGNC:6763Mapping file id4085 NCBI fileEvidenceTAS
GeneMAPRE1AuthorityHGNC:6890Mapping file id22919 NCBI fileEvidenceTAS
GeneMIS12AuthorityHGNC:24967Mapping file id79003 NCBI fileEvidenceTAS
GeneNDC1AuthorityHGNC:25525Mapping file id55706 NCBI fileEvidenceIEA, TAS
GeneNDC80AuthorityHGNC:16909Mapping file id10403 NCBI fileEvidenceTAS
GeneNDE1AuthorityHGNC:17619Mapping file id54820 NCBI fileEvidenceTAS
GeneNDEL1AuthorityHGNC:17620Mapping file id81565 NCBI fileEvidenceTAS
GeneNSL1AuthorityHGNC:24548Mapping file id25936 NCBI fileEvidenceTAS
GeneNUDCAuthorityHGNC:8045Mapping file id10726 NCBI fileEvidenceTAS
GeneNUF2AuthorityHGNC:14621Mapping file id83540 NCBI fileEvidenceTAS
GeneNUP107AuthorityHGNC:29914Mapping file id57122 NCBI fileEvidenceIEA, TAS
GeneNUP133AuthorityHGNC:18016Mapping file id55746 NCBI fileEvidenceIEA, TAS
GeneNUP155AuthorityHGNC:8063Mapping file id9631 NCBI fileEvidenceIEA, TAS

Evidence codes on this page: IEA, TAS, as the mapping file writes them; a row carrying two was written twice by the file, once under each. The mapping file id says which file placed the gene: an NCBI Gene id from NCBI2Reactome_All_Levels.txt, an Ensembl gene id from Ensembl2Reactome_All_Levels.txt. The two files can disagree about a code, so a row's codes are the one file's view. Measured by this site's build over this release on 2026-09-09: of the 138,908 human pathway-gene pairs both files place, 207 (0.149 per cent, over 47 genes) carry TAS in the Ensembl file where the NCBI rows carry IEA alone.

  • Reactome mapping files, the human rows for this pathway · Reactome release 97 · read · Reactome downloads"NCBI2Reactome_All_Levels.txt" and "Ensembl2Reactome_All_Levels.txt", Reactome, release 97, https://reactome.org/download-data/ (date of access 2026-09-09). Data CC0; attribution encouraged.

03The hierarchy

Parents and children in this release's hierarchy

Reactome's hierarchy is a graph rather than a tree: a pathway can sit under more than one parent, and the gene counts are each pathway's own placements at every level under it, so a parent's count is not the sum of its children's.

  • Reactome, the human pathway list and hierarchy relationship file · Reactome release 97 · read · Reactome downloads"ReactomePathways.txt" and "ReactomePathwaysRelation.txt", Reactome, release 97, https://reactome.org/download-data/ (date of access 2026-09-09). Data CC0; attribution encouraged.