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Pathway Human Homo sapiens

Nuclear Envelope (NE) Reassembly

R-HSA-2995410 in Reactome release 97: under Mitotic Anaphase, with 77 genes placed in it by the mapping files and 3 child pathways in the hierarchy.

The same number in the other species

Reactome writes the mouse and rat events it infers from a human pathway under the human number with the species token. A door opens only where that species' own list in this release holds the id: R-MMU-2995410 (mouse), R-RNO-2995410 (rat). Whether the event was inferred from this one is what the record says.

01The record

Reactome's own record of this pathway

What this tells you

The pathway list, the hierarchy and the genes on this page are read from the files Reactome publishes for Reactome release 97, built into this site on 2026-09-09: the pathway list, the hierarchy relationship file and the two gene mapping files. The record card is the one live read, Reactome's own record of this pathway.

Reactome's download page describes the mapping files: Mapping files link the source database identifier to the lowest level pathway diagram or subset of the pathway, all levels of the pathway hierarchy or database identifier to all reactions. [R13] The gene list here is the all-levels mapping of NCBI Gene ids, filled from the all-levels mapping of Ensembl ids where the NCBI file has no row for a gene; each row names which file it came from by the shape of its source id. Each row carries the evidence codes the file writes for it, as written and unranked, and both where the file writes both; no page of Reactome's documentation the survey read defines the codes, so this page does not expand them. A gene id the identity files do not name is kept as the source's own id with no door rather than turned into a symbol.

On citing what a search finds, Reactome says: It should be remembered that while we strive to contain the most current and accurate data, Reactome should not be used in citations where other primary sources of information are available. [R12] The record card prints the literature Reactome attaches to a curated pathway for that reason. The data are public domain: All data in the Reactome database and files derived from that data are licensed under the Creative Commons Public Domain Dedication (CC0). User may copy, modify, and distribute these data, even for commercial purposes, without asking for permission. Attribution is encouraged but not required. [R10] The pathway illustrations are licensed apart, under CC BY 4.0, and none is shown here.

A gene on this list is one Reactome places in this pathway in this release, and that is all the row says: it does not say the gene is expressed in a tissue or associated with a disease, which are the other two explorers' questions, read from other sources. Reactome's papers of record are [R01] [R02].

  1. [R01] Ragueneau E, Gong C, Sinquin P, Sevilla C, Beavers D, Grentner A, et al. (2026). The Reactome Knowledgebase 2026. Nucleic Acids Research 54:D673-D681. PMID 41251150, doi 10.1093/nar/gkaf1223.
  2. [R02] Milacic M, Beavers D, Conley P, Gong C, Gillespie M, Griss J, et al. (2024). The Reactome Pathway Knowledgebase 2024. Nucleic Acids Research 52:D672-D678. PMID 37941124, doi 10.1093/nar/gkad1025.
  3. [R10] Reactome, reactome.org. License Agreement. https://reactome.org/license, read 2026-09-09.
  4. [R12] Reactome, reactome.org. Citing us. https://reactome.org/cite, read 2026-09-09.
  5. [R13] Reactome, reactome.org. Download. https://reactome.org/download-data, read 2026-09-09.
Reading this pathway's record from Reactome (the pathway record).Still reading. A first read of a pathway can take a while; this page waits up to 35 seconds for it, and its scripts then bring in the panel, or a line saying what did not arrive.

02The genes

Genes Reactome places in this human pathway

The mapping files place 77 genes in this human pathway; showing 1 to 77, in pages of 100, sorted by symbol for reading. The order carries no ranking.

Genes Reactome places in this human pathway, page 1 of 1
GeneAHCTF1AuthorityHGNC:24618Mapping file id25909 NCBI fileEvidenceIEA, TAS
GeneANKLE2AuthorityHGNC:29101Mapping file id23141 NCBI fileEvidenceTAS
GeneBANF1AuthorityHGNC:17397Mapping file id8815 NCBI fileEvidenceTAS
GeneCC2D1BAuthorityHGNC:29386Mapping file id200014 NCBI fileEvidenceTAS
GeneCCNB1AuthorityHGNC:1579Mapping file id891 NCBI fileEvidenceTAS
GeneCCNB2AuthorityHGNC:1580Mapping file id9133 NCBI fileEvidenceTAS
GeneCDK1AuthorityHGNC:1722Mapping file id983 NCBI fileEvidenceTAS
GeneCHMP2AAuthorityHGNC:30216Mapping file id27243 NCBI fileEvidenceTAS
GeneCHMP2BAuthorityHGNC:24537Mapping file id25978 NCBI fileEvidenceTAS
GeneCHMP3AuthorityHGNC:29865Mapping file id51652 NCBI fileEvidenceTAS
GeneCHMP4AAuthorityHGNC:20274Mapping file id29082 NCBI fileEvidenceTAS
GeneCHMP4BAuthorityHGNC:16171Mapping file id128866 NCBI fileEvidenceTAS
GeneCHMP4CAuthorityHGNC:30599Mapping file id92421 NCBI fileEvidenceTAS
GeneCHMP6AuthorityHGNC:25675Mapping file id79643 NCBI fileEvidenceTAS
GeneCHMP7AuthorityHGNC:28439Mapping file id91782 NCBI fileEvidenceTAS
GeneEMDAuthorityHGNC:3331Mapping file id2010 NCBI fileEvidenceTAS
GeneIST1AuthorityHGNC:28977Mapping file id9798 NCBI fileEvidenceTAS
GeneKPNB1AuthorityHGNC:6400Mapping file id3837 NCBI fileEvidenceIEA, TAS
GeneLBRAuthorityHGNC:6518Mapping file id3930 NCBI fileEvidenceTAS
GeneLEMD2AuthorityHGNC:21244Mapping file id221496 NCBI fileEvidenceTAS
GeneLEMD3AuthorityHGNC:28887Mapping file id23592 NCBI fileEvidenceTAS
GeneLMNAAuthorityHGNC:6636Mapping file id4000 NCBI fileEvidenceTAS
GeneLMNB1AuthorityHGNC:6637Mapping file id4001 NCBI fileEvidenceTAS
GeneNDC1AuthorityHGNC:25525Mapping file id55706 NCBI fileEvidenceIEA, TAS
GeneNUP107AuthorityHGNC:29914Mapping file id57122 NCBI fileEvidenceIEA, TAS
GeneNUP133AuthorityHGNC:18016Mapping file id55746 NCBI fileEvidenceIEA, TAS
GeneNUP155AuthorityHGNC:8063Mapping file id9631 NCBI fileEvidenceIEA, TAS
GeneNUP160AuthorityHGNC:18017Mapping file id23279 NCBI fileEvidenceIEA, TAS
GeneNUP188AuthorityHGNC:17859Mapping file id23511 NCBI fileEvidenceIEA, TAS
GeneNUP205AuthorityHGNC:18658Mapping file id23165 NCBI fileEvidenceIEA, TAS
GeneNUP35AuthorityHGNC:29797Mapping file id129401 NCBI fileEvidenceIEA, TAS
GeneNUP37AuthorityHGNC:29929Mapping file id79023 NCBI fileEvidenceIEA, TAS
GeneNUP43AuthorityHGNC:21182Mapping file id348995 NCBI fileEvidenceIEA, TAS
GeneNUP54AuthorityHGNC:17359Mapping file id53371 NCBI fileEvidenceIEA
GeneNUP58AuthorityHGNC:20261Mapping file id9818 NCBI fileEvidenceIEA
GeneNUP62AuthorityHGNC:8066Mapping file id23636 NCBI fileEvidenceIEA
GeneNUP85AuthorityHGNC:8734Mapping file id79902 NCBI fileEvidenceIEA, TAS
GeneNUP93AuthorityHGNC:28958Mapping file id9688 NCBI fileEvidenceIEA, TAS
GeneNUP98AuthorityHGNC:8068Mapping file id4928 NCBI fileEvidenceIEA, TAS
GenePOM121AuthorityHGNC:19702Mapping file id9883 NCBI fileEvidenceIEA, TAS
GenePPP2CAAuthorityHGNC:9299Mapping file id5515 NCBI fileEvidenceTAS
GenePPP2R1AAuthorityHGNC:9302Mapping file id5518 NCBI fileEvidenceTAS
GenePPP2R2AAuthorityHGNC:9304Mapping file id5520 NCBI fileEvidenceTAS
GeneRANAuthorityHGNC:9846Mapping file id5901 NCBI fileEvidenceIEA, TAS
GeneRANGAP1AuthorityHGNC:9854Mapping file id5905 NCBI fileEvidenceTAS
GeneRCC1AuthorityHGNC:1913Mapping file id1104 NCBI fileEvidenceTAS
GeneRNF103-CHMP3AuthorityHGNC:38847Mapping file id100526767 NCBI fileEvidenceTAS
GeneSEC13AuthorityHGNC:10697Mapping file id6396 NCBI fileEvidenceIEA, TAS
GeneSEH1LAuthorityHGNC:30379Mapping file id81929 NCBI fileEvidenceIEA, TAS
GeneSIRT2AuthorityHGNC:10886Mapping file id22933 NCBI fileEvidenceTAS
GeneSPASTAuthorityHGNC:11233Mapping file id6683 NCBI fileEvidenceTAS
GeneSUMO1AuthorityHGNC:12502Mapping file id7341 NCBI fileEvidenceTAS
GeneTMPOAuthorityHGNC:11875Mapping file id7112 NCBI fileEvidenceTAS
GeneTNPO1AuthorityHGNC:6401Mapping file id3842 NCBI fileEvidenceIEA
GeneTUBA1AAuthorityHGNC:20766Mapping file id7846 NCBI fileEvidenceTAS
GeneTUBA1BAuthorityHGNC:18809Mapping file id10376 NCBI fileEvidenceTAS
GeneTUBA1CAuthorityHGNC:20768Mapping file id84790 NCBI fileEvidenceTAS
GeneTUBA3CAuthorityHGNC:12408Mapping file id7278 NCBI fileEvidenceTAS
GeneTUBA3DAuthorityHGNC:24071Mapping file id113457 NCBI fileEvidenceTAS
GeneTUBA3EAuthorityHGNC:20765Mapping file id112714 NCBI fileEvidenceTAS
GeneTUBA4AAuthorityHGNC:12407Mapping file id7277 NCBI fileEvidenceTAS
GeneTUBA4BAuthorityHGNC:18637Mapping file id80086 NCBI fileEvidenceTAS
GeneTUBA8AuthorityHGNC:12410Mapping file id51807 NCBI fileEvidenceTAS
GeneTUBAL3AuthorityHGNC:23534Mapping file id79861 NCBI fileEvidenceTAS
GeneTUBB1AuthorityHGNC:16257Mapping file id81027 NCBI fileEvidenceTAS
GeneTUBB2AAuthorityHGNC:12412Mapping file id7280 NCBI fileEvidenceTAS
GeneTUBB2BAuthorityHGNC:30829Mapping file id347733 NCBI fileEvidenceTAS
GeneTUBB3AuthorityHGNC:20772Mapping file id10381 NCBI fileEvidenceTAS
GeneTUBB4AAuthorityHGNC:20774Mapping file id10382 NCBI fileEvidenceTAS
GeneTUBB4BAuthorityHGNC:20771Mapping file id10383 NCBI fileEvidenceTAS
GeneTUBB6AuthorityHGNC:20776Mapping file id84617 NCBI fileEvidenceTAS
GeneTUBB8AuthorityHGNC:20773Mapping file id347688 NCBI fileEvidenceTAS
GeneTUBB8BAuthorityHGNC:24983Mapping file id260334 NCBI fileEvidenceTAS
GeneUBE2IAuthorityHGNC:12485Mapping file id7329 NCBI fileEvidenceTAS
GeneVPS4AAuthorityHGNC:13488Mapping file id27183 NCBI fileEvidenceTAS
GeneVRK1AuthorityHGNC:12718Mapping file id7443 NCBI fileEvidenceTAS
GeneVRK2AuthorityHGNC:12719Mapping file id7444 NCBI fileEvidenceTAS

Evidence codes on this page: IEA, TAS, as the mapping file writes them; a row carrying two was written twice by the file, once under each. The mapping file id says which file placed the gene: an NCBI Gene id from NCBI2Reactome_All_Levels.txt, an Ensembl gene id from Ensembl2Reactome_All_Levels.txt. The two files can disagree about a code, so a row's codes are the one file's view. Measured by this site's build over this release on 2026-09-09: of the 138,908 human pathway-gene pairs both files place, 207 (0.149 per cent, over 47 genes) carry TAS in the Ensembl file where the NCBI rows carry IEA alone.

  • Reactome mapping files, the human rows for this pathway · Reactome release 97 · read · Reactome downloads"NCBI2Reactome_All_Levels.txt" and "Ensembl2Reactome_All_Levels.txt", Reactome, release 97, https://reactome.org/download-data/ (date of access 2026-09-09). Data CC0; attribution encouraged.

03The hierarchy

Parents and children in this release's hierarchy

Reactome's hierarchy is a graph rather than a tree: a pathway can sit under more than one parent, and the gene counts are each pathway's own placements at every level under it, so a parent's count is not the sum of its children's.

  • Reactome, the human pathway list and hierarchy relationship file · Reactome release 97 · read · Reactome downloads"ReactomePathways.txt" and "ReactomePathwaysRelation.txt", Reactome, release 97, https://reactome.org/download-data/ (date of access 2026-09-09). Data CC0; attribution encouraged.