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Pathway Human Homo sapiens

G1 Phase

R-HSA-69236 in Reactome release 97: under Mitotic G1 phase and G1/S transition, with 47 genes placed in it by the mapping files and 1 child pathway in the hierarchy.

The same number in the other species

Reactome writes the mouse and rat events it infers from a human pathway under the human number with the species token. A door opens only where that species' own list in this release holds the id: R-MMU-69236 (mouse), R-RNO-69236 (rat). Whether the event was inferred from this one is what the record says.

01The record

Reactome's own record of this pathway

What this tells you

The pathway list, the hierarchy and the genes on this page are read from the files Reactome publishes for Reactome release 97, built into this site on 2026-09-09: the pathway list, the hierarchy relationship file and the two gene mapping files. The record card is the one live read, Reactome's own record of this pathway.

Reactome's download page describes the mapping files: Mapping files link the source database identifier to the lowest level pathway diagram or subset of the pathway, all levels of the pathway hierarchy or database identifier to all reactions. [R13] The gene list here is the all-levels mapping of NCBI Gene ids, filled from the all-levels mapping of Ensembl ids where the NCBI file has no row for a gene; each row names which file it came from by the shape of its source id. Each row carries the evidence codes the file writes for it, as written and unranked, and both where the file writes both; no page of Reactome's documentation the survey read defines the codes, so this page does not expand them. A gene id the identity files do not name is kept as the source's own id with no door rather than turned into a symbol.

On citing what a search finds, Reactome says: It should be remembered that while we strive to contain the most current and accurate data, Reactome should not be used in citations where other primary sources of information are available. [R12] The record card prints the literature Reactome attaches to a curated pathway for that reason. The data are public domain: All data in the Reactome database and files derived from that data are licensed under the Creative Commons Public Domain Dedication (CC0). User may copy, modify, and distribute these data, even for commercial purposes, without asking for permission. Attribution is encouraged but not required. [R10] The pathway illustrations are licensed apart, under CC BY 4.0, and none is shown here.

A gene on this list is one Reactome places in this pathway in this release, and that is all the row says: it does not say the gene is expressed in a tissue or associated with a disease, which are the other two explorers' questions, read from other sources. Reactome's papers of record are [R01] [R02].

  1. [R01] Ragueneau E, Gong C, Sinquin P, Sevilla C, Beavers D, Grentner A, et al. (2026). The Reactome Knowledgebase 2026. Nucleic Acids Research 54:D673-D681. PMID 41251150, doi 10.1093/nar/gkaf1223.
  2. [R02] Milacic M, Beavers D, Conley P, Gong C, Gillespie M, Griss J, et al. (2024). The Reactome Pathway Knowledgebase 2024. Nucleic Acids Research 52:D672-D678. PMID 37941124, doi 10.1093/nar/gkad1025.
  3. [R10] Reactome, reactome.org. License Agreement. https://reactome.org/license, read 2026-09-09.
  4. [R12] Reactome, reactome.org. Citing us. https://reactome.org/cite, read 2026-09-09.
  5. [R13] Reactome, reactome.org. Download. https://reactome.org/download-data, read 2026-09-09.
Reading this pathway's record from Reactome (the pathway record).Still reading. A first read of a pathway can take a while; this page waits up to 35 seconds for it, and its scripts then bring in the panel, or a line saying what did not arrive.

02The genes

Genes Reactome places in this human pathway

The mapping files place 47 genes in this human pathway; showing 1 to 47, in pages of 100, sorted by symbol for reading. The order carries no ranking.

Genes Reactome places in this human pathway, page 1 of 1
GeneABL1AuthorityHGNC:76Mapping file id25 NCBI fileEvidenceTAS
GeneCCND1AuthorityHGNC:1582Mapping file id595 NCBI fileEvidenceTAS
GeneCCND2AuthorityHGNC:1583Mapping file id894 NCBI fileEvidenceTAS
GeneCCND3AuthorityHGNC:1585Mapping file id896 NCBI fileEvidenceTAS
GeneCCNE1AuthorityHGNC:1589Mapping file id898 NCBI fileEvidenceTAS
GeneCCNE2AuthorityHGNC:1590Mapping file id9134 NCBI fileEvidenceTAS
GeneCCNHAuthorityHGNC:1594Mapping file id902 NCBI fileEvidenceTAS
GeneCDK2AuthorityHGNC:1771Mapping file id1017 NCBI fileEvidenceTAS
GeneCDK4AuthorityHGNC:1773Mapping file id1019 NCBI fileEvidenceTAS
GeneCDK6AuthorityHGNC:1777Mapping file id1021 NCBI fileEvidenceTAS
GeneCDK7AuthorityHGNC:1778Mapping file id1022 NCBI fileEvidenceTAS
GeneCDKN1AAuthorityHGNC:1784Mapping file id1026 NCBI fileEvidenceTAS
GeneCDKN1BAuthorityHGNC:1785Mapping file id1027 NCBI fileEvidenceTAS
GeneCDKN1CAuthorityHGNC:1786Mapping file id1028 NCBI fileEvidenceTAS
GeneCDKN2AAuthorityHGNC:1787Mapping file id1029 NCBI fileEvidenceTAS
GeneCDKN2BAuthorityHGNC:1788Mapping file id1030 NCBI fileEvidenceTAS
GeneCDKN2CAuthorityHGNC:1789Mapping file id1031 NCBI fileEvidenceTAS
GeneCDKN2DAuthorityHGNC:1790Mapping file id1032 NCBI fileEvidenceTAS
GeneCKS1BAuthorityHGNC:19083Mapping file id1163 NCBI fileEvidenceTAS
GeneCUL1AuthorityHGNC:2551Mapping file id8454 NCBI fileEvidenceTAS
GeneE2F1AuthorityHGNC:3113Mapping file id1869 NCBI fileEvidenceTAS
GeneE2F2AuthorityHGNC:3114Mapping file id1870 NCBI fileEvidenceTAS
GeneE2F3AuthorityHGNC:3115Mapping file id1871 NCBI fileEvidenceTAS
GeneE2F4AuthorityHGNC:3118Mapping file id1874 NCBI fileEvidenceTAS
GeneE2F5AuthorityHGNC:3119Mapping file id1875 NCBI fileEvidenceTAS
GeneJAK2AuthorityHGNC:6192Mapping file id3717 NCBI fileEvidenceTAS
GeneLYNAuthorityHGNC:6735Mapping file id4067 NCBI fileEvidenceTAS
GeneMNAT1AuthorityHGNC:7181Mapping file id4331 NCBI fileEvidenceTAS
GenePPP2CAAuthorityHGNC:9299Mapping file id5515 NCBI fileEvidenceTAS
GenePPP2CBAuthorityHGNC:9300Mapping file id5516 NCBI fileEvidenceTAS
GenePPP2R1AAuthorityHGNC:9302Mapping file id5518 NCBI fileEvidenceTAS
GenePPP2R1BAuthorityHGNC:9303Mapping file id5519 NCBI fileEvidenceTAS
GenePPP2R2AAuthorityHGNC:9304Mapping file id5520 NCBI fileEvidenceTAS
GenePPP2R3BAuthorityHGNC:13417Mapping file id28227 NCBI fileEvidenceTAS
GenePTK6AuthorityHGNC:9617Mapping file id5753 NCBI fileEvidenceTAS
GeneRB1AuthorityHGNC:9884Mapping file id5925 NCBI fileEvidenceTAS
GeneRBL1AuthorityHGNC:9893Mapping file id5933 NCBI fileEvidenceTAS
GeneRBL2AuthorityHGNC:9894Mapping file id5934 NCBI fileEvidenceTAS
GeneRPS27AAuthorityHGNC:10417Mapping file id6233 NCBI fileEvidenceTAS
GeneSKP1AuthorityHGNC:10899Mapping file id6500 NCBI fileEvidenceTAS
GeneSKP2AuthorityHGNC:10901Mapping file id6502 NCBI fileEvidenceTAS
GeneSRCAuthorityHGNC:11283Mapping file id6714 NCBI fileEvidenceTAS
GeneTFDP1AuthorityHGNC:11749Mapping file id7027 NCBI fileEvidenceTAS
GeneTFDP2AuthorityHGNC:11751Mapping file id7029 NCBI fileEvidenceTAS
GeneUBA52AuthorityHGNC:12458Mapping file id7311 NCBI fileEvidenceTAS
GeneUBBAuthorityHGNC:12463Mapping file id7314 NCBI fileEvidenceTAS
GeneUBCAuthorityHGNC:12468Mapping file id7316 NCBI fileEvidenceTAS

Evidence codes on this page: TAS, as the mapping file writes them; a row carrying two was written twice by the file, once under each. The mapping file id says which file placed the gene: an NCBI Gene id from NCBI2Reactome_All_Levels.txt, an Ensembl gene id from Ensembl2Reactome_All_Levels.txt. The two files can disagree about a code, so a row's codes are the one file's view. Measured by this site's build over this release on 2026-09-09: of the 138,908 human pathway-gene pairs both files place, 207 (0.149 per cent, over 47 genes) carry TAS in the Ensembl file where the NCBI rows carry IEA alone.

  • Reactome mapping files, the human rows for this pathway · Reactome release 97 · read · Reactome downloads"NCBI2Reactome_All_Levels.txt" and "Ensembl2Reactome_All_Levels.txt", Reactome, release 97, https://reactome.org/download-data/ (date of access 2026-09-09). Data CC0; attribution encouraged.

03The hierarchy

Parents and children in this release's hierarchy

Reactome's hierarchy is a graph rather than a tree: a pathway can sit under more than one parent, and the gene counts are each pathway's own placements at every level under it, so a parent's count is not the sum of its children's.

  • Reactome, the human pathway list and hierarchy relationship file · Reactome release 97 · read · Reactome downloads"ReactomePathways.txt" and "ReactomePathwaysRelation.txt", Reactome, release 97, https://reactome.org/download-data/ (date of access 2026-09-09). Data CC0; attribution encouraged.