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Pathway Human Homo sapiens

Golgi-to-ER retrograde transport

R-HSA-8856688 in Reactome release 97: under Intra-Golgi and retrograde Golgi-to-ER traffic, with 134 genes placed in it by the mapping files and 2 child pathways in the hierarchy.

The same number in the other species

Reactome writes the mouse and rat events it infers from a human pathway under the human number with the species token. A door opens only where that species' own list in this release holds the id: R-MMU-8856688 (mouse), R-RNO-8856688 (rat). Whether the event was inferred from this one is what the record says.

01The record

Reactome's own record of this pathway

What this tells you

The pathway list, the hierarchy and the genes on this page are read from the files Reactome publishes for Reactome release 97, built into this site on 2026-09-09: the pathway list, the hierarchy relationship file and the two gene mapping files. The record card is the one live read, Reactome's own record of this pathway.

Reactome's download page describes the mapping files: Mapping files link the source database identifier to the lowest level pathway diagram or subset of the pathway, all levels of the pathway hierarchy or database identifier to all reactions. [R13] The gene list here is the all-levels mapping of NCBI Gene ids, filled from the all-levels mapping of Ensembl ids where the NCBI file has no row for a gene; each row names which file it came from by the shape of its source id. Each row carries the evidence codes the file writes for it, as written and unranked, and both where the file writes both; no page of Reactome's documentation the survey read defines the codes, so this page does not expand them. A gene id the identity files do not name is kept as the source's own id with no door rather than turned into a symbol.

On citing what a search finds, Reactome says: It should be remembered that while we strive to contain the most current and accurate data, Reactome should not be used in citations where other primary sources of information are available. [R12] The record card prints the literature Reactome attaches to a curated pathway for that reason. The data are public domain: All data in the Reactome database and files derived from that data are licensed under the Creative Commons Public Domain Dedication (CC0). User may copy, modify, and distribute these data, even for commercial purposes, without asking for permission. Attribution is encouraged but not required. [R10] The pathway illustrations are licensed apart, under CC BY 4.0, and none is shown here.

A gene on this list is one Reactome places in this pathway in this release, and that is all the row says: it does not say the gene is expressed in a tissue or associated with a disease, which are the other two explorers' questions, read from other sources. Reactome's papers of record are [R01] [R02].

  1. [R01] Ragueneau E, Gong C, Sinquin P, Sevilla C, Beavers D, Grentner A, et al. (2026). The Reactome Knowledgebase 2026. Nucleic Acids Research 54:D673-D681. PMID 41251150, doi 10.1093/nar/gkaf1223.
  2. [R02] Milacic M, Beavers D, Conley P, Gong C, Gillespie M, Griss J, et al. (2024). The Reactome Pathway Knowledgebase 2024. Nucleic Acids Research 52:D672-D678. PMID 37941124, doi 10.1093/nar/gkad1025.
  3. [R10] Reactome, reactome.org. License Agreement. https://reactome.org/license, read 2026-09-09.
  4. [R12] Reactome, reactome.org. Citing us. https://reactome.org/cite, read 2026-09-09.
  5. [R13] Reactome, reactome.org. Download. https://reactome.org/download-data, read 2026-09-09.
Reading this pathway's record from Reactome (the pathway record).Still reading. A first read of a pathway can take a while; this page waits up to 35 seconds for it, and its scripts then bring in the panel, or a line saying what did not arrive.

02The genes

Genes Reactome places in this human pathway

The mapping files place 134 genes in this human pathway; showing 1 to 100, in pages of 100, sorted by symbol for reading. The order carries no ranking.

Genes Reactome places in this human pathway, page 1 of 2
GeneACTR10AuthorityHGNC:17372Mapping file id55860 NCBI fileEvidenceTAS
GeneACTR1AAuthorityHGNC:167Mapping file id10121 NCBI fileEvidenceTAS
GeneAGPAT3AuthorityHGNC:326Mapping file id56894 NCBI fileEvidenceTAS
GeneARCN1AuthorityHGNC:649Mapping file id372 NCBI fileEvidenceTAS
GeneARF1AuthorityHGNC:652Mapping file id375 NCBI fileEvidenceTAS
GeneARF3AuthorityHGNC:654Mapping file id377 NCBI fileEvidenceTAS
GeneARF4AuthorityHGNC:655Mapping file id378 NCBI fileEvidenceTAS
GeneARF5AuthorityHGNC:658Mapping file id381 NCBI fileEvidenceTAS
GeneARFGAP1AuthorityHGNC:15852Mapping file id55738 NCBI fileEvidenceTAS
GeneARFGAP2AuthorityHGNC:13504Mapping file id84364 NCBI fileEvidenceTAS
GeneARFGAP3AuthorityHGNC:661Mapping file id26286 NCBI fileEvidenceTAS
GeneBICD1AuthorityHGNC:1049Mapping file id636 NCBI fileEvidenceTAS
GeneBICD2AuthorityHGNC:17208Mapping file id23299 NCBI fileEvidenceTAS
GeneBNIP1AuthorityHGNC:1082Mapping file id662 NCBI fileEvidenceTAS
GeneCAPZA1AuthorityHGNC:1488Mapping file id829 NCBI fileEvidenceTAS
GeneCAPZA2AuthorityHGNC:1490Mapping file id830 NCBI fileEvidenceTAS
GeneCAPZA3AuthorityHGNC:24205Mapping file id93661 NCBI fileEvidenceTAS
GeneCAPZBAuthorityHGNC:1491Mapping file id832 NCBI fileEvidenceTAS
GeneCENPEAuthorityHGNC:1856Mapping file id1062 NCBI fileEvidenceTAS
GeneCOPAAuthorityHGNC:2230Mapping file id1314 NCBI fileEvidenceTAS
GeneCOPB1AuthorityHGNC:2231Mapping file id1315 NCBI fileEvidenceTAS
GeneCOPB2AuthorityHGNC:2232Mapping file id9276 NCBI fileEvidenceTAS
GeneCOPEAuthorityHGNC:2234Mapping file id11316 NCBI fileEvidenceTAS
GeneCOPG1AuthorityHGNC:2236Mapping file id22820 NCBI fileEvidenceTAS
GeneCOPG2AuthorityHGNC:2237Mapping file id26958 NCBI fileEvidenceTAS
GeneCOPZ1AuthorityHGNC:2243Mapping file id22818 NCBI fileEvidenceTAS
GeneCOPZ2AuthorityHGNC:19356Mapping file id51226 NCBI fileEvidenceTAS
GeneDCTN1AuthorityHGNC:2711Mapping file id1639 NCBI fileEvidenceTAS
GeneDCTN2AuthorityHGNC:2712Mapping file id10540 NCBI fileEvidenceTAS
GeneDCTN3AuthorityHGNC:2713Mapping file id11258 NCBI fileEvidenceTAS
GeneDCTN4AuthorityHGNC:15518Mapping file id51164 NCBI fileEvidenceTAS
GeneDCTN5AuthorityHGNC:24594Mapping file id84516 NCBI fileEvidenceTAS
GeneDCTN6AuthorityHGNC:16964Mapping file id10671 NCBI fileEvidenceTAS
GeneDYNC1H1AuthorityHGNC:2961Mapping file id1778 NCBI fileEvidenceTAS
GeneDYNC1I1AuthorityHGNC:2963Mapping file id1780 NCBI fileEvidenceTAS
GeneDYNC1I2AuthorityHGNC:2964Mapping file id1781 NCBI fileEvidenceTAS
GeneDYNC1LI1AuthorityHGNC:18745Mapping file id51143 NCBI fileEvidenceTAS
GeneDYNC1LI2AuthorityHGNC:2966Mapping file id1783 NCBI fileEvidenceTAS
GeneDYNLL1AuthorityHGNC:15476Mapping file id8655 NCBI fileEvidenceTAS
GeneDYNLL2AuthorityHGNC:24596Mapping file id140735 NCBI fileEvidenceTAS
GeneGALNT1AuthorityHGNC:4123Mapping file id2589 NCBI fileEvidenceTAS
GeneGALNT2AuthorityHGNC:4124Mapping file id2590 NCBI fileEvidenceTAS
GeneGBF1AuthorityHGNC:4181Mapping file id8729 NCBI fileEvidenceTAS
GeneKDELR1AuthorityHGNC:6304Mapping file id10945 NCBI fileEvidenceTAS
GeneKDELR2AuthorityHGNC:6305Mapping file id11014 NCBI fileEvidenceTAS
GeneKDELR3AuthorityHGNC:6306Mapping file id11015 NCBI fileEvidenceTAS
GeneKIF11AuthorityHGNC:6388Mapping file id3832 NCBI fileEvidenceTAS
GeneKIF12AuthorityHGNC:21495Mapping file id113220 NCBI fileEvidenceTAS
GeneKIF13BAuthorityHGNC:14405Mapping file id23303 NCBI fileEvidenceTAS
GeneKIF15AuthorityHGNC:17273Mapping file id56992 NCBI fileEvidenceTAS
GeneKIF16BAuthorityHGNC:15869Mapping file id55614 NCBI fileEvidenceTAS
GeneKIF18AAuthorityHGNC:29441Mapping file id81930 NCBI fileEvidenceTAS
GeneKIF18BAuthorityHGNC:27102Mapping file id146909 NCBI fileEvidenceTAS
GeneKIF19AuthorityHGNC:26735Mapping file id124602 NCBI fileEvidenceTAS
GeneKIF1AAuthorityHGNC:888Mapping file id547 NCBI fileEvidenceTAS
GeneKIF1BAuthorityHGNC:16636Mapping file id23095 NCBI fileEvidenceTAS
GeneKIF1CAuthorityHGNC:6317Mapping file id10749 NCBI fileEvidenceTAS
GeneKIF20AAuthorityHGNC:9787Mapping file id10112 NCBI fileEvidenceTAS
GeneKIF20BAuthorityHGNC:7212Mapping file id9585 NCBI fileEvidenceTAS
GeneKIF21AAuthorityHGNC:19349Mapping file id55605 NCBI fileEvidenceTAS
GeneKIF21BAuthorityHGNC:29442Mapping file id23046 NCBI fileEvidenceTAS
GeneKIF22AuthorityHGNC:6391Mapping file id3835 NCBI fileEvidenceTAS
GeneKIF23AuthorityHGNC:6392Mapping file id9493 NCBI fileEvidenceTAS
GeneKIF25AuthorityHGNC:6390Mapping file id3834 NCBI fileEvidenceTAS
GeneKIF26AAuthorityHGNC:20226Mapping file id26153 NCBI fileEvidenceTAS
GeneKIF26BAuthorityHGNC:25484Mapping file id55083 NCBI fileEvidenceTAS
GeneKIF27AuthorityHGNC:18632Mapping file id55582 NCBI fileEvidenceTAS
GeneKIF2AAuthorityHGNC:6318Mapping file id3796 NCBI fileEvidenceTAS
GeneKIF2BAuthorityHGNC:29443Mapping file id84643 NCBI fileEvidenceTAS
GeneKIF2CAuthorityHGNC:6393Mapping file id11004 NCBI fileEvidenceTAS
GeneKIF3AAuthorityHGNC:6319Mapping file id11127 NCBI fileEvidenceTAS
GeneKIF3BAuthorityHGNC:6320Mapping file id9371 NCBI fileEvidenceTAS
GeneKIF3CAuthorityHGNC:6321Mapping file id3797 NCBI fileEvidenceTAS
GeneKIF4AAuthorityHGNC:13339Mapping file id24137 NCBI fileEvidenceTAS
GeneKIF4BAuthorityHGNC:6322Mapping file id285643 NCBI fileEvidenceTAS
GeneKIF5AAuthorityHGNC:6323Mapping file id3798 NCBI fileEvidenceTAS
GeneKIF5BAuthorityHGNC:6324Mapping file id3799 NCBI fileEvidenceTAS
GeneKIF6AuthorityHGNC:21202Mapping file id221458 NCBI fileEvidenceTAS
GeneKIF9AuthorityHGNC:16666Mapping file id64147 NCBI fileEvidenceTAS
GeneKIFAP3AuthorityHGNC:17060Mapping file id22920 NCBI fileEvidenceTAS
GeneKIFC1AuthorityHGNC:6389Mapping file id3833 NCBI fileEvidenceTAS
GeneKIFC2AuthorityHGNC:29530Mapping file id90990 NCBI fileEvidenceTAS
GeneKLC1AuthorityHGNC:6387Mapping file id3831 NCBI fileEvidenceTAS
GeneKLC2AuthorityHGNC:20716Mapping file id64837 NCBI fileEvidenceTAS
GeneKLC3AuthorityHGNC:20717Mapping file id147700 NCBI fileEvidenceTAS
GeneKLC4AuthorityHGNC:21624Mapping file id89953 NCBI fileEvidenceTAS
GeneNAPAAuthorityHGNC:7641Mapping file id8775 NCBI fileEvidenceTAS
GeneNAPBAuthorityHGNC:15751Mapping file id63908 NCBI fileEvidenceTAS
GeneNAPGAuthorityHGNC:7642Mapping file id8774 NCBI fileEvidenceTAS
GeneNBASAuthorityHGNC:15625Mapping file id51594 NCBI fileEvidenceTAS
GeneNSFAuthorityHGNC:8016Mapping file id4905 NCBI fileEvidenceTAS
GenePAFAH1B1AuthorityHGNC:8574Mapping file id5048 NCBI fileEvidenceTAS
GenePAFAH1B2AuthorityHGNC:8575Mapping file id5049 NCBI fileEvidenceTAS
GenePAFAH1B3AuthorityHGNC:8576Mapping file id5050 NCBI fileEvidenceTAS
GenePLA2G4AAuthorityHGNC:9035Mapping file id5321 NCBI fileEvidenceTAS
GenePLA2G6AuthorityHGNC:9039Mapping file id8398 NCBI fileEvidenceTAS
GeneRAB18AuthorityHGNC:14244Mapping file id22931 NCBI fileEvidenceTAS
GeneRAB1AAuthorityHGNC:9758Mapping file id5861 NCBI fileEvidenceTAS
GeneRAB1BAuthorityHGNC:18370Mapping file id81876 NCBI fileEvidenceTAS
GeneRAB3GAP1AuthorityHGNC:17063Mapping file id22930 NCBI fileEvidenceTAS

Evidence codes on this page: TAS, as the mapping file writes them; a row carrying two was written twice by the file, once under each. The mapping file id says which file placed the gene: an NCBI Gene id from NCBI2Reactome_All_Levels.txt, an Ensembl gene id from Ensembl2Reactome_All_Levels.txt. The two files can disagree about a code, so a row's codes are the one file's view. Measured by this site's build over this release on 2026-09-09: of the 138,908 human pathway-gene pairs both files place, 207 (0.149 per cent, over 47 genes) carry TAS in the Ensembl file where the NCBI rows carry IEA alone.

  • Reactome mapping files, the human rows for this pathway · Reactome release 97 · read · Reactome downloads"NCBI2Reactome_All_Levels.txt" and "Ensembl2Reactome_All_Levels.txt", Reactome, release 97, https://reactome.org/download-data/ (date of access 2026-09-09). Data CC0; attribution encouraged.

03The hierarchy

Parents and children in this release's hierarchy

Reactome's hierarchy is a graph rather than a tree: a pathway can sit under more than one parent, and the gene counts are each pathway's own placements at every level under it, so a parent's count is not the sum of its children's.

  • Reactome, the human pathway list and hierarchy relationship file · Reactome release 97 · read · Reactome downloads"ReactomePathways.txt" and "ReactomePathwaysRelation.txt", Reactome, release 97, https://reactome.org/download-data/ (date of access 2026-09-09). Data CC0; attribution encouraged.