Pathway Human Homo sapiens
Intra-Golgi and retrograde Golgi-to-ER traffic
R-HSA-6811442 in Reactome release 97: under Membrane Trafficking, with 203 genes placed in it by the mapping files and 3 child pathways in the hierarchy.
The same number in the other species
Reactome writes the mouse and rat events it infers from a human pathway under the human number with the species token. A door opens only where that species' own list in this release holds the id: R-MMU-6811442 (mouse), R-RNO-6811442 (rat). Whether the event was inferred from this one is what the record says.
01The record
Reactome's own record of this pathway
What this tells you
The pathway list, the hierarchy and the genes on this page are read from the files Reactome publishes for Reactome release 97, built into this site on 2026-09-09: the pathway list, the hierarchy relationship file and the two gene mapping files. The record card is the one live read, Reactome's own record of this pathway.
Reactome's download page describes the mapping files: Mapping files link the source database identifier to the lowest level pathway diagram or subset of the pathway, all levels of the pathway hierarchy or database identifier to all reactions.
[R13] The gene list here is the all-levels mapping of NCBI Gene ids, filled from the all-levels mapping of Ensembl ids where the NCBI file has no row for a gene; each row names which file it came from by the shape of its source id. Each row carries the evidence codes the file writes for it, as written and unranked, and both where the file writes both; no page of Reactome's documentation the survey read defines the codes, so this page does not expand them. A gene id the identity files do not name is kept as the source's own id with no door rather than turned into a symbol.
On citing what a search finds, Reactome says: It should be remembered that while we strive to contain the most current and accurate data, Reactome should not be used in citations where other primary sources of information are available.
[R12] The record card prints the literature Reactome attaches to a curated pathway for that reason. The data are public domain: All data in the Reactome database and files derived from that data are licensed under the Creative Commons Public Domain Dedication (CC0). User may copy, modify, and distribute these data, even for commercial purposes, without asking for permission. Attribution is encouraged but not required.
[R10] The pathway illustrations are licensed apart, under CC BY 4.0, and none is shown here.
A gene on this list is one Reactome places in this pathway in this release, and that is all the row says: it does not say the gene is expressed in a tissue or associated with a disease, which are the other two explorers' questions, read from other sources. Reactome's papers of record are [R01] [R02].
- [R01] Ragueneau E, Gong C, Sinquin P, Sevilla C, Beavers D, Grentner A, et al. (2026). The Reactome Knowledgebase 2026. Nucleic Acids Research 54:D673-D681. PMID 41251150, doi 10.1093/nar/gkaf1223.
- [R02] Milacic M, Beavers D, Conley P, Gong C, Gillespie M, Griss J, et al. (2024). The Reactome Pathway Knowledgebase 2024. Nucleic Acids Research 52:D672-D678. PMID 37941124, doi 10.1093/nar/gkad1025.
- [R10] Reactome, reactome.org. License Agreement. https://reactome.org/license, read 2026-09-09.
- [R12] Reactome, reactome.org. Citing us. https://reactome.org/cite, read 2026-09-09.
- [R13] Reactome, reactome.org. Download. https://reactome.org/download-data, read 2026-09-09.
02The genes
Genes Reactome places in this human pathway
The mapping files place 203 genes in this human pathway; showing 1 to 100, in pages of 100, sorted by symbol for reading. The order carries no ranking.
| Gene | Authority id | Mapping file id | Evidence codes |
|---|---|---|---|
| GeneACTR10 | AuthorityHGNC:17372 | Mapping file id55860 NCBI file | EvidenceTAS |
| GeneACTR1A | AuthorityHGNC:167 | Mapping file id10121 NCBI file | EvidenceTAS |
| GeneAGPAT3 | AuthorityHGNC:326 | Mapping file id56894 NCBI file | EvidenceTAS |
| GeneALPP | AuthorityHGNC:439 | Mapping file id250 NCBI file | EvidenceTAS |
| GeneARCN1 | AuthorityHGNC:649 | Mapping file id372 NCBI file | EvidenceTAS |
| GeneARF1 | AuthorityHGNC:652 | Mapping file id375 NCBI file | EvidenceTAS |
| GeneARF3 | AuthorityHGNC:654 | Mapping file id377 NCBI file | EvidenceTAS |
| GeneARF4 | AuthorityHGNC:655 | Mapping file id378 NCBI file | EvidenceTAS |
| GeneARF5 | AuthorityHGNC:658 | Mapping file id381 NCBI file | EvidenceTAS |
| GeneARFGAP1 | AuthorityHGNC:15852 | Mapping file id55738 NCBI file | EvidenceTAS |
| GeneARFGAP2 | AuthorityHGNC:13504 | Mapping file id84364 NCBI file | EvidenceTAS |
| GeneARFGAP3 | AuthorityHGNC:661 | Mapping file id26286 NCBI file | EvidenceTAS |
| GeneARFIP2 | AuthorityHGNC:17160 | Mapping file id23647 NCBI file | EvidenceTAS |
| GeneARFRP1 | AuthorityHGNC:662 | Mapping file id10139 NCBI file | EvidenceIEA, TAS |
| GeneARL1 | AuthorityHGNC:692 | Mapping file id400 NCBI file | EvidenceTAS |
| GeneBET1L | AuthorityHGNC:19348 | Mapping file id51272 NCBI file | EvidenceTAS |
| GeneBICD1 | AuthorityHGNC:1049 | Mapping file id636 NCBI file | EvidenceTAS |
| GeneBICD2 | AuthorityHGNC:17208 | Mapping file id23299 NCBI file | EvidenceTAS |
| GeneBNIP1 | AuthorityHGNC:1082 | Mapping file id662 NCBI file | EvidenceTAS |
| GeneCAPZA1 | AuthorityHGNC:1488 | Mapping file id829 NCBI file | EvidenceTAS |
| GeneCAPZA2 | AuthorityHGNC:1490 | Mapping file id830 NCBI file | EvidenceTAS |
| GeneCAPZA3 | AuthorityHGNC:24205 | Mapping file id93661 NCBI file | EvidenceTAS |
| GeneCAPZB | AuthorityHGNC:1491 | Mapping file id832 NCBI file | EvidenceTAS |
| GeneCENPE | AuthorityHGNC:1856 | Mapping file id1062 NCBI file | EvidenceTAS |
| GeneCOG1 | AuthorityHGNC:6545 | Mapping file id9382 NCBI file | EvidenceTAS |
| GeneCOG2 | AuthorityHGNC:6546 | Mapping file id22796 NCBI file | EvidenceTAS |
| GeneCOG3 | AuthorityHGNC:18619 | Mapping file id83548 NCBI file | EvidenceTAS |
| GeneCOG4 | AuthorityHGNC:18620 | Mapping file id25839 NCBI file | EvidenceTAS |
| GeneCOG5 | AuthorityHGNC:14857 | Mapping file id10466 NCBI file | EvidenceTAS |
| GeneCOG6 | AuthorityHGNC:18621 | Mapping file id57511 NCBI file | EvidenceTAS |
| GeneCOG7 | AuthorityHGNC:18622 | Mapping file id91949 NCBI file | EvidenceTAS |
| GeneCOG8 | AuthorityHGNC:18623 | Mapping file id84342 NCBI file | EvidenceTAS |
| GeneCOPA | AuthorityHGNC:2230 | Mapping file id1314 NCBI file | EvidenceTAS |
| GeneCOPB1 | AuthorityHGNC:2231 | Mapping file id1315 NCBI file | EvidenceTAS |
| GeneCOPB2 | AuthorityHGNC:2232 | Mapping file id9276 NCBI file | EvidenceTAS |
| GeneCOPE | AuthorityHGNC:2234 | Mapping file id11316 NCBI file | EvidenceTAS |
| GeneCOPG1 | AuthorityHGNC:2236 | Mapping file id22820 NCBI file | EvidenceTAS |
| GeneCOPG2 | AuthorityHGNC:2237 | Mapping file id26958 NCBI file | EvidenceTAS |
| GeneCOPZ1 | AuthorityHGNC:2243 | Mapping file id22818 NCBI file | EvidenceTAS |
| GeneCOPZ2 | AuthorityHGNC:19356 | Mapping file id51226 NCBI file | EvidenceTAS |
| GeneCUX1 | AuthorityHGNC:2557 | Mapping file id1523 NCBI file | EvidenceTAS |
| GeneCYTH1 | AuthorityHGNC:9501 | Mapping file id9267 NCBI file | EvidenceTAS |
| GeneCYTH2 | AuthorityHGNC:9502 | Mapping file id9266 NCBI file | EvidenceTAS |
| GeneCYTH3 | AuthorityHGNC:9504 | Mapping file id9265 NCBI file | EvidenceTAS |
| GeneCYTH4 | AuthorityHGNC:9505 | Mapping file id27128 NCBI file | EvidenceTAS |
| GeneDCTN1 | AuthorityHGNC:2711 | Mapping file id1639 NCBI file | EvidenceTAS |
| GeneDCTN2 | AuthorityHGNC:2712 | Mapping file id10540 NCBI file | EvidenceTAS |
| GeneDCTN3 | AuthorityHGNC:2713 | Mapping file id11258 NCBI file | EvidenceTAS |
| GeneDCTN4 | AuthorityHGNC:15518 | Mapping file id51164 NCBI file | EvidenceTAS |
| GeneDCTN5 | AuthorityHGNC:24594 | Mapping file id84516 NCBI file | EvidenceTAS |
| GeneDCTN6 | AuthorityHGNC:16964 | Mapping file id10671 NCBI file | EvidenceTAS |
| GeneDYNC1H1 | AuthorityHGNC:2961 | Mapping file id1778 NCBI file | EvidenceTAS |
| GeneDYNC1I1 | AuthorityHGNC:2963 | Mapping file id1780 NCBI file | EvidenceTAS |
| GeneDYNC1I2 | AuthorityHGNC:2964 | Mapping file id1781 NCBI file | EvidenceTAS |
| GeneDYNC1LI1 | AuthorityHGNC:18745 | Mapping file id51143 NCBI file | EvidenceTAS |
| GeneDYNC1LI2 | AuthorityHGNC:2966 | Mapping file id1783 NCBI file | EvidenceTAS |
| GeneDYNLL1 | AuthorityHGNC:15476 | Mapping file id8655 NCBI file | EvidenceTAS |
| GeneDYNLL2 | AuthorityHGNC:24596 | Mapping file id140735 NCBI file | EvidenceTAS |
| GeneGALNT1 | AuthorityHGNC:4123 | Mapping file id2589 NCBI file | EvidenceTAS |
| GeneGALNT2 | AuthorityHGNC:4124 | Mapping file id2590 NCBI file | EvidenceTAS |
| GeneGBF1 | AuthorityHGNC:4181 | Mapping file id8729 NCBI file | EvidenceTAS |
| GeneGCC1 | AuthorityHGNC:19095 | Mapping file id79571 NCBI file | EvidenceTAS |
| GeneGCC2 | AuthorityHGNC:23218 | Mapping file id9648 NCBI file | EvidenceTAS |
| GeneGOLGA1 | AuthorityHGNC:4424 | Mapping file id2800 NCBI file | EvidenceTAS |
| GeneGOLGA4 | AuthorityHGNC:4427 | Mapping file id2803 NCBI file | EvidenceTAS |
| GeneGOLGA5 | AuthorityHGNC:4428 | Mapping file id9950 NCBI file | EvidenceTAS |
| GeneGOLIM4 | AuthorityHGNC:15448 | Mapping file id27333 NCBI file | EvidenceTAS |
| GeneGOSR1 | AuthorityHGNC:4430 | Mapping file id9527 NCBI file | EvidenceTAS |
| GeneGOSR2 | AuthorityHGNC:4431 | Mapping file id9570 NCBI file | EvidenceTAS |
| GeneIGF2R | AuthorityHGNC:5467 | Mapping file id3482 NCBI file | EvidenceTAS |
| GeneKDELR1 | AuthorityHGNC:6304 | Mapping file id10945 NCBI file | EvidenceTAS |
| GeneKDELR2 | AuthorityHGNC:6305 | Mapping file id11014 NCBI file | EvidenceTAS |
| GeneKDELR3 | AuthorityHGNC:6306 | Mapping file id11015 NCBI file | EvidenceTAS |
| GeneKIF11 | AuthorityHGNC:6388 | Mapping file id3832 NCBI file | EvidenceTAS |
| GeneKIF12 | AuthorityHGNC:21495 | Mapping file id113220 NCBI file | EvidenceTAS |
| GeneKIF13B | AuthorityHGNC:14405 | Mapping file id23303 NCBI file | EvidenceTAS |
| GeneKIF15 | AuthorityHGNC:17273 | Mapping file id56992 NCBI file | EvidenceTAS |
| GeneKIF16B | AuthorityHGNC:15869 | Mapping file id55614 NCBI file | EvidenceTAS |
| GeneKIF18A | AuthorityHGNC:29441 | Mapping file id81930 NCBI file | EvidenceTAS |
| GeneKIF18B | AuthorityHGNC:27102 | Mapping file id146909 NCBI file | EvidenceTAS |
| GeneKIF19 | AuthorityHGNC:26735 | Mapping file id124602 NCBI file | EvidenceTAS |
| GeneKIF1A | AuthorityHGNC:888 | Mapping file id547 NCBI file | EvidenceTAS |
| GeneKIF1B | AuthorityHGNC:16636 | Mapping file id23095 NCBI file | EvidenceTAS |
| GeneKIF1C | AuthorityHGNC:6317 | Mapping file id10749 NCBI file | EvidenceTAS |
| GeneKIF20A | AuthorityHGNC:9787 | Mapping file id10112 NCBI file | EvidenceTAS |
| GeneKIF20B | AuthorityHGNC:7212 | Mapping file id9585 NCBI file | EvidenceTAS |
| GeneKIF21A | AuthorityHGNC:19349 | Mapping file id55605 NCBI file | EvidenceTAS |
| GeneKIF21B | AuthorityHGNC:29442 | Mapping file id23046 NCBI file | EvidenceTAS |
| GeneKIF22 | AuthorityHGNC:6391 | Mapping file id3835 NCBI file | EvidenceTAS |
| GeneKIF23 | AuthorityHGNC:6392 | Mapping file id9493 NCBI file | EvidenceTAS |
| GeneKIF25 | AuthorityHGNC:6390 | Mapping file id3834 NCBI file | EvidenceTAS |
| GeneKIF26A | AuthorityHGNC:20226 | Mapping file id26153 NCBI file | EvidenceTAS |
| GeneKIF26B | AuthorityHGNC:25484 | Mapping file id55083 NCBI file | EvidenceTAS |
| GeneKIF27 | AuthorityHGNC:18632 | Mapping file id55582 NCBI file | EvidenceTAS |
| GeneKIF2A | AuthorityHGNC:6318 | Mapping file id3796 NCBI file | EvidenceTAS |
| GeneKIF2B | AuthorityHGNC:29443 | Mapping file id84643 NCBI file | EvidenceTAS |
| GeneKIF2C | AuthorityHGNC:6393 | Mapping file id11004 NCBI file | EvidenceTAS |
| GeneKIF3A | AuthorityHGNC:6319 | Mapping file id11127 NCBI file | EvidenceTAS |
| GeneKIF3B | AuthorityHGNC:6320 | Mapping file id9371 NCBI file | EvidenceTAS |
| GeneKIF3C | AuthorityHGNC:6321 | Mapping file id3797 NCBI file | EvidenceTAS |
Evidence codes on this page: IEA, TAS, as the mapping file writes them; a row carrying two was written twice by the file, once under each. The mapping file id says which file placed the gene: an NCBI Gene id from NCBI2Reactome_All_Levels.txt, an Ensembl gene id from Ensembl2Reactome_All_Levels.txt. The two files can disagree about a code, so a row's codes are the one file's view. Measured by this site's build over this release on 2026-09-09: of the 138,908 human pathway-gene pairs both files place, 207 (0.149 per cent, over 47 genes) carry TAS in the Ensembl file where the NCBI rows carry IEA alone.
- Reactome mapping files, the human rows for this pathway · Reactome release 97 · read · Reactome downloads"NCBI2Reactome_All_Levels.txt" and "Ensembl2Reactome_All_Levels.txt", Reactome, release 97, https://reactome.org/download-data/ (date of access 2026-09-09). Data CC0; attribution encouraged.
03The hierarchy
Parents and children in this release's hierarchy
Reactome's hierarchy is a graph rather than a tree: a pathway can sit under more than one parent, and the gene counts are each pathway's own placements at every level under it, so a parent's count is not the sum of its children's.
- Reactome, the human pathway list and hierarchy relationship file · Reactome release 97 · read · Reactome downloads"ReactomePathways.txt" and "ReactomePathwaysRelation.txt", Reactome, release 97, https://reactome.org/download-data/ (date of access 2026-09-09). Data CC0; attribution encouraged.