Skip to content

Create an account and get up to 25% off.

Order

Pathway Human Homo sapiens

Olfactory Signaling Pathway

R-HSA-381753 in Reactome release 97: under Sensory Perception, with 418 genes placed in it by the mapping files and 1 child pathway in the hierarchy.

The same number in the other species

Reactome writes the mouse and rat events it infers from a human pathway under the human number with the species token. A door opens only where that species' own list in this release holds the id: R-MMU-381753 (mouse). Whether the event was inferred from this one is what the record says.

01The record

Reactome's own record of this pathway

What this tells you

The pathway list, the hierarchy and the genes on this page are read from the files Reactome publishes for Reactome release 97, built into this site on 2026-09-09: the pathway list, the hierarchy relationship file and the two gene mapping files. The record card is the one live read, Reactome's own record of this pathway.

Reactome's download page describes the mapping files: Mapping files link the source database identifier to the lowest level pathway diagram or subset of the pathway, all levels of the pathway hierarchy or database identifier to all reactions. [R13] The gene list here is the all-levels mapping of NCBI Gene ids, filled from the all-levels mapping of Ensembl ids where the NCBI file has no row for a gene; each row names which file it came from by the shape of its source id. Each row carries the evidence codes the file writes for it, as written and unranked, and both where the file writes both; no page of Reactome's documentation the survey read defines the codes, so this page does not expand them. A gene id the identity files do not name is kept as the source's own id with no door rather than turned into a symbol.

On citing what a search finds, Reactome says: It should be remembered that while we strive to contain the most current and accurate data, Reactome should not be used in citations where other primary sources of information are available. [R12] The record card prints the literature Reactome attaches to a curated pathway for that reason. The data are public domain: All data in the Reactome database and files derived from that data are licensed under the Creative Commons Public Domain Dedication (CC0). User may copy, modify, and distribute these data, even for commercial purposes, without asking for permission. Attribution is encouraged but not required. [R10] The pathway illustrations are licensed apart, under CC BY 4.0, and none is shown here.

A gene on this list is one Reactome places in this pathway in this release, and that is all the row says: it does not say the gene is expressed in a tissue or associated with a disease, which are the other two explorers' questions, read from other sources. Reactome's papers of record are [R01] [R02].

  1. [R01] Ragueneau E, Gong C, Sinquin P, Sevilla C, Beavers D, Grentner A, et al. (2026). The Reactome Knowledgebase 2026. Nucleic Acids Research 54:D673-D681. PMID 41251150, doi 10.1093/nar/gkaf1223.
  2. [R02] Milacic M, Beavers D, Conley P, Gong C, Gillespie M, Griss J, et al. (2024). The Reactome Pathway Knowledgebase 2024. Nucleic Acids Research 52:D672-D678. PMID 37941124, doi 10.1093/nar/gkad1025.
  3. [R10] Reactome, reactome.org. License Agreement. https://reactome.org/license, read 2026-09-09.
  4. [R12] Reactome, reactome.org. Citing us. https://reactome.org/cite, read 2026-09-09.
  5. [R13] Reactome, reactome.org. Download. https://reactome.org/download-data, read 2026-09-09.
Reading this pathway's record from Reactome (the pathway record).Still reading. A first read of a pathway can take a while; this page waits up to 35 seconds for it, and its scripts then bring in the panel, or a line saying what did not arrive.

02The genes

Genes Reactome places in this human pathway

The mapping files place 418 genes in this human pathway; showing 1 to 100, in pages of 100, sorted by symbol for reading. The order carries no ranking.

Genes Reactome places in this human pathway, page 1 of 5
GeneADCY3AuthorityHGNC:234Mapping file id109 NCBI fileEvidenceIEA
GeneANO2AuthorityHGNC:1183Mapping file id57101 NCBI fileEvidenceIEA
GeneCNGA2AuthorityHGNC:2149Mapping file id1260 NCBI fileEvidenceIEA
GeneCNGA4AuthorityHGNC:2152Mapping file id1262 NCBI fileEvidenceIEA
GeneCNGB1AuthorityHGNC:2151Mapping file id1258 NCBI fileEvidenceIEA
GeneEBF1AuthorityHGNC:3126Mapping file id1879 NCBI fileEvidenceIEA
GeneGNALAuthorityHGNC:4388Mapping file id2774 NCBI fileEvidenceIEA, TAS
GeneGNB1AuthorityHGNC:4396Mapping file id2782 NCBI fileEvidenceIEA, TAS
GeneGNG13AuthorityHGNC:14131Mapping file id51764 NCBI fileEvidenceIEA, TAS
GeneLDB1AuthorityHGNC:6532Mapping file id8861 NCBI fileEvidenceIEA
GeneLHX2AuthorityHGNC:6594Mapping file id9355 NCBI fileEvidenceIEA
GeneOR10A2AuthorityHGNC:8161Mapping file id341276 NCBI fileEvidenceIEA
GeneOR10A3AuthorityHGNC:8162Mapping file id26496 NCBI fileEvidenceIEA
GeneOR10A4AuthorityHGNC:15130Mapping file id283297 NCBI fileEvidenceIEA
GeneOR10A5AuthorityHGNC:15131Mapping file id144124 NCBI fileEvidenceIEA
GeneOR10A6AuthorityHGNC:15132Mapping file id390093 NCBI fileEvidenceIEA, TAS
GeneOR10A7AuthorityHGNC:15329Mapping file id121364 NCBI fileEvidenceIEA
GeneOR10AC1AuthorityHGNC:14758Mapping file idENSG00000176510 Ensembl fileEvidenceIEA
GeneOR10AD1AuthorityHGNC:14819Mapping file id121275 NCBI fileEvidenceIEA
GeneOR10AG1AuthorityHGNC:19607Mapping file id282770 NCBI fileEvidenceIEA
GeneOR10C1AuthorityHGNC:8165Mapping file id442194 NCBI fileEvidenceIEA
GeneOR10D3AuthorityHGNC:8168Mapping file id26497 NCBI fileEvidenceIEA
GeneOR10G2AuthorityHGNC:8170Mapping file id26534 NCBI fileEvidenceIEA
GeneOR10G3AuthorityHGNC:8171Mapping file id26533 NCBI fileEvidenceIEA, TAS
GeneOR10G4AuthorityHGNC:14809Mapping file id390264 NCBI fileEvidenceIEA, TAS
GeneOR10G6AuthorityHGNC:14836Mapping file id79490 NCBI fileEvidenceIEA
GeneOR10G7AuthorityHGNC:14842Mapping file id390265 NCBI fileEvidenceIEA, TAS
GeneOR10G8AuthorityHGNC:14845Mapping file id219869 NCBI fileEvidenceIEA
GeneOR10G9AuthorityHGNC:15129Mapping file id219870 NCBI fileEvidenceIEA
GeneOR10H1AuthorityHGNC:8172Mapping file id26539 NCBI fileEvidenceIEA
GeneOR10H2AuthorityHGNC:8173Mapping file id26538 NCBI fileEvidenceIEA, TAS
GeneOR10H3AuthorityHGNC:8174Mapping file id26532 NCBI fileEvidenceIEA
GeneOR10H4AuthorityHGNC:15388Mapping file id126541 NCBI fileEvidenceIEA
GeneOR10H5AuthorityHGNC:15389Mapping file id284433 NCBI fileEvidenceIEA, TAS
GeneOR10J1AuthorityHGNC:8175Mapping file id26476 NCBI fileEvidenceIEA
GeneOR10J3AuthorityHGNC:14992Mapping file idENSG00000196266 Ensembl fileEvidenceIEA
GeneOR10J4AuthorityHGNC:15408Mapping file id391121 NCBI fileEvidenceIEA
GeneOR10J5AuthorityHGNC:14993Mapping file id127385 NCBI fileEvidenceIEA, TAS
GeneOR10K1AuthorityHGNC:14693Mapping file id391109 NCBI fileEvidenceIEA
GeneOR10K2AuthorityHGNC:14826Mapping file id391107 NCBI fileEvidenceIEA
GeneOR10P1AuthorityHGNC:15378Mapping file id121130 NCBI fileEvidenceIEA
GeneOR10Q1AuthorityHGNC:15134Mapping file id219960 NCBI fileEvidenceIEA
GeneOR10R2AuthorityHGNC:14820Mapping file id343406 NCBI fileEvidenceIEA
GeneOR10S1AuthorityHGNC:14807Mapping file id219873 NCBI fileEvidenceIEA, TAS
GeneOR10T2AuthorityHGNC:14816Mapping file id128360 NCBI fileEvidenceIEA
GeneOR10V1AuthorityHGNC:15136Mapping file id390201 NCBI fileEvidenceIEA
GeneOR10W1AuthorityHGNC:15139Mapping file id81341 NCBI fileEvidenceIEA
GeneOR10X1AuthorityHGNC:14995Mapping file id128367 NCBI fileEvidenceIEA, TAS
GeneOR10Z1AuthorityHGNC:14996Mapping file id128368 NCBI fileEvidenceIEA
GeneOR11A1AuthorityHGNC:8176Mapping file id26531 NCBI fileEvidenceIEA, TAS
GeneOR11G2AuthorityHGNC:15346Mapping file id390439 NCBI fileEvidenceIEA
GeneOR11H1AuthorityHGNC:15404Mapping file id81061 NCBI fileEvidenceIEA
GeneOR11H2AuthorityHGNC:14716Mapping file id79334 NCBI fileEvidenceIEA
GeneOR11H4AuthorityHGNC:15347Mapping file id390442 NCBI fileEvidenceIEA, TAS
GeneOR11H6AuthorityHGNC:15349Mapping file id122748 NCBI fileEvidenceIEA, TAS
GeneOR11H7AuthorityHGNC:15350Mapping file id390441 NCBI fileEvidenceIEA
GeneOR11L1AuthorityHGNC:14998Mapping file id391189 NCBI fileEvidenceIEA
GeneOR12D2AuthorityHGNC:8178Mapping file id26529 NCBI fileEvidenceIEA
GeneOR12D3AuthorityHGNC:13963Mapping file id81797 NCBI fileEvidenceIEA
GeneOR13A1AuthorityHGNC:14772Mapping file id79290 NCBI fileEvidenceIEA
GeneOR13C2AuthorityHGNC:14701Mapping file id392376 NCBI fileEvidenceIEA
GeneOR13C3AuthorityHGNC:14704Mapping file id138803 NCBI fileEvidenceIEA, TAS
GeneOR13C4AuthorityHGNC:14722Mapping file id138804 NCBI fileEvidenceIEA
GeneOR13C5AuthorityHGNC:15100Mapping file id138799 NCBI fileEvidenceIEA
GeneOR13C8AuthorityHGNC:15103Mapping file id138802 NCBI fileEvidenceIEA
GeneOR13C9AuthorityHGNC:15104Mapping file id286362 NCBI fileEvidenceIEA
GeneOR13D1AuthorityHGNC:14695Mapping file id286365 NCBI fileEvidenceIEA
GeneOR13F1AuthorityHGNC:14723Mapping file id138805 NCBI fileEvidenceIEA
GeneOR13G1AuthorityHGNC:14999Mapping file id441933 NCBI fileEvidenceIEA
GeneOR13H1AuthorityHGNC:14755Mapping file id347468 NCBI fileEvidenceIEA
GeneOR13J1AuthorityHGNC:15108Mapping file id392309 NCBI fileEvidenceIEA
GeneOR14A16AuthorityHGNC:15022Mapping file id284532 NCBI fileEvidenceIEA
GeneOR14A2AuthorityHGNC:15024Mapping file id388761 NCBI fileEvidenceIEA, TAS
GeneOR14C36AuthorityHGNC:15026Mapping file id127066 NCBI fileEvidenceIEA
GeneOR14I1AuthorityHGNC:19575Mapping file id401994 NCBI fileEvidenceIEA
GeneOR14J1AuthorityHGNC:13971Mapping file id442191 NCBI fileEvidenceIEA, TAS
GeneOR14K1AuthorityHGNC:15025Mapping file id343170 NCBI fileEvidenceIEA
GeneOR1A1AuthorityHGNC:8179Mapping file id8383 NCBI fileEvidenceIEA, TAS
GeneOR1A2AuthorityHGNC:8180Mapping file id26189 NCBI fileEvidenceIEA
GeneOR1B1AuthorityHGNC:8181Mapping file id347169 NCBI fileEvidenceIEA
GeneOR1C1AuthorityHGNC:8182Mapping file id26188 NCBI fileEvidenceIEA, TAS
GeneOR1D2AuthorityHGNC:8183Mapping file id4991 NCBI fileEvidenceIEA, TAS
GeneOR1D4AuthorityHGNC:8185Mapping file idENSG00000255095 Ensembl fileEvidenceIEA
GeneOR1D5AuthorityHGNC:8186Mapping file id8386 NCBI fileEvidenceIEA, TAS
GeneOR1E1AuthorityHGNC:8189Mapping file id8387 NCBI fileEvidenceIEA, TAS
GeneOR1E2AuthorityHGNC:8190Mapping file id8388 NCBI fileEvidenceIEA
GeneOR1E3AuthorityHGNC:8191Mapping file idENSG00000142163 Ensembl fileEvidenceIEA
GeneOR1F1AuthorityHGNC:8194Mapping file id4992 NCBI fileEvidenceIEA
GeneOR1F12PAuthorityHGNC:13964Mapping file idENSG00000220721 Ensembl fileEvidenceIEA
GeneOR1G1AuthorityHGNC:8204Mapping file id8390 NCBI fileEvidenceIEA
GeneOR1I1AuthorityHGNC:8207Mapping file id126370 NCBI fileEvidenceIEA
GeneOR1J1AuthorityHGNC:8208Mapping file id347168 NCBI fileEvidenceIEA
GeneOR1J2AuthorityHGNC:8209Mapping file id26740 NCBI fileEvidenceIEA
GeneOR1J4AuthorityHGNC:8211Mapping file id26219 NCBI fileEvidenceIEA
GeneOR1K1AuthorityHGNC:8212Mapping file id392392 NCBI fileEvidenceIEA
GeneOR1L1AuthorityHGNC:8213Mapping file id26737 NCBI fileEvidenceIEA
GeneOR1L3AuthorityHGNC:8215Mapping file id26735 NCBI fileEvidenceIEA
GeneOR1L4AuthorityHGNC:8216Mapping file id254973 NCBI fileEvidenceIEA
GeneOR1L6AuthorityHGNC:8218Mapping file id392390 NCBI fileEvidenceIEA
GeneOR1L8AuthorityHGNC:15110Mapping file id138881 NCBI fileEvidenceIEA

Evidence codes on this page: IEA, TAS, as the mapping file writes them; a row carrying two was written twice by the file, once under each. The mapping file id says which file placed the gene: an NCBI Gene id from NCBI2Reactome_All_Levels.txt, an Ensembl gene id from Ensembl2Reactome_All_Levels.txt. The two files can disagree about a code, so a row's codes are the one file's view. Measured by this site's build over this release on 2026-09-09: of the 138,908 human pathway-gene pairs both files place, 207 (0.149 per cent, over 47 genes) carry TAS in the Ensembl file where the NCBI rows carry IEA alone.

  • Reactome mapping files, the human rows for this pathway · Reactome release 97 · read · Reactome downloads"NCBI2Reactome_All_Levels.txt" and "Ensembl2Reactome_All_Levels.txt", Reactome, release 97, https://reactome.org/download-data/ (date of access 2026-09-09). Data CC0; attribution encouraged.

03The hierarchy

Parents and children in this release's hierarchy

Reactome's hierarchy is a graph rather than a tree: a pathway can sit under more than one parent, and the gene counts are each pathway's own placements at every level under it, so a parent's count is not the sum of its children's.

  • Reactome, the human pathway list and hierarchy relationship file · Reactome release 97 · read · Reactome downloads"ReactomePathways.txt" and "ReactomePathwaysRelation.txt", Reactome, release 97, https://reactome.org/download-data/ (date of access 2026-09-09). Data CC0; attribution encouraged.