Skip to content

Create an account and get up to 25% off.

Order

Pathway Mouse Mus musculus

Read this first

Every mouse pathway in Reactome is electronically inferred from the curated human one; Reactome's own sentence about that stands beside the record below.

SLC-mediated transport of inorganic anions

R-MMU-9958790 in Reactome release 97: under SLC-mediated transmembrane transport, with 35 genes placed in it by the mapping files and 5 child pathways in the hierarchy.

The same number in the other species

Reactome writes the mouse and rat events it infers from a human pathway under the human number with the species token. A door opens only where that species' own list in this release holds the id: R-HSA-9958790 (human), R-RNO-9958790 (rat). Whether the event was inferred from this one is what the record says.

01The record

Reactome's own record of this pathway

What this tells you

The pathway list, the hierarchy and the genes on this page are read from the files Reactome publishes for Reactome release 97, built into this site on 2026-09-09: the pathway list, the hierarchy relationship file and the two gene mapping files. The record card is the one live read, Reactome's own record of this pathway.

Reactome's download page describes the mapping files: Mapping files link the source database identifier to the lowest level pathway diagram or subset of the pathway, all levels of the pathway hierarchy or database identifier to all reactions. [R13] The gene list here is the all-levels mapping of NCBI Gene ids, filled from the all-levels mapping of Ensembl ids where the NCBI file has no row for a gene; each row names which file it came from by the shape of its source id. Each row carries the evidence codes the file writes for it, as written and unranked, and both where the file writes both; no page of Reactome's documentation the survey read defines the codes, so this page does not expand them. A gene id the identity files do not name is kept as the source's own id with no door rather than turned into a symbol.

Every mouse pathway in Reactome is inferred from the curated human one: We use the set of manually curated human reactions to electronically infer reactions in fourteen evolutionarily divergent eukaryotic species for which high-quality whole-genome sequence data are available, and hence a comprehensive and high-quality set of protein predictions exists. [R11] Reactome's own sentence about what that produces is printed beside the record: The electronically inferred reactions presented in Reactome are thus not data, but hypotheses useful to direct the design of confirmatory experiments. [R11]

On citing what a search finds, Reactome says: It should be remembered that while we strive to contain the most current and accurate data, Reactome should not be used in citations where other primary sources of information are available. [R12] The record card prints the literature Reactome attaches to a curated pathway for that reason. The data are public domain: All data in the Reactome database and files derived from that data are licensed under the Creative Commons Public Domain Dedication (CC0). User may copy, modify, and distribute these data, even for commercial purposes, without asking for permission. Attribution is encouraged but not required. [R10] The pathway illustrations are licensed apart, under CC BY 4.0, and none is shown here.

A gene on this list is one Reactome places in this pathway in this release, and that is all the row says: it does not say the gene is expressed in a tissue or associated with a disease, which are the other two explorers' questions, read from other sources. Reactome's papers of record are [R01] [R02].

  1. [R01] Ragueneau E, Gong C, Sinquin P, Sevilla C, Beavers D, Grentner A, et al. (2026). The Reactome Knowledgebase 2026. Nucleic Acids Research 54:D673-D681. PMID 41251150, doi 10.1093/nar/gkaf1223.
  2. [R02] Milacic M, Beavers D, Conley P, Gong C, Gillespie M, Griss J, et al. (2024). The Reactome Pathway Knowledgebase 2024. Nucleic Acids Research 52:D672-D678. PMID 37941124, doi 10.1093/nar/gkad1025.
  3. [R10] Reactome, reactome.org. License Agreement. https://reactome.org/license, read 2026-09-09.
  4. [R11] Reactome, reactome.org. Computationally inferred events. https://reactome.org/documentation/inferred-events, read 2026-09-09.
  5. [R12] Reactome, reactome.org. Citing us. https://reactome.org/cite, read 2026-09-09.
  6. [R13] Reactome, reactome.org. Download. https://reactome.org/download-data, read 2026-09-09.
Reading this pathway's record from Reactome (the pathway record).Still reading. A first read of a pathway can take a while; this page waits up to 35 seconds for it, and its scripts then bring in the panel, or a line saying what did not arrive.

02The genes

Genes Reactome places in this mouse pathway

The mapping files place 35 genes in this mouse pathway; showing 1 to 35, in pages of 100, sorted by symbol for reading. The order carries no ranking.

Genes Reactome places in this mouse pathway, page 1 of 1
GeneAhcyl2Authority74340Mapping file id74340 NCBI fileEvidenceIEA
GeneSlc12a1Authority20495Mapping file id20495 NCBI fileEvidenceIEA
GeneSlc12a2Authority20496Mapping file id20496 NCBI fileEvidenceIEA
GeneSlc12a3Authority20497Mapping file id20497 NCBI fileEvidenceIEA
GeneSlc12a4Authority20498Mapping file id20498 NCBI fileEvidenceIEA
GeneSlc12a5Authority57138Mapping file id57138 NCBI fileEvidenceIEA
GeneSlc12a6Authority107723Mapping file id107723 NCBI fileEvidenceIEA
GeneSlc12a7Authority20499Mapping file id20499 NCBI fileEvidenceIEA
GeneSlc13a1Authority55961Mapping file id55961 NCBI fileEvidenceIEA
GeneSlc13a4Authority243755Mapping file id243755 NCBI fileEvidenceIEA
GeneSlc17a1Authority20504Mapping file id20504 NCBI fileEvidenceIEA
GeneSlc20a1Authority20515Mapping file id20515 NCBI fileEvidenceIEA
GeneSlc20a2Authority20516Mapping file id20516 NCBI fileEvidenceIEA
GeneSlc26a1Authority231583Mapping file id231583 NCBI fileEvidenceIEA
GeneSlc26a11Authority268512Mapping file id268512 NCBI fileEvidenceIEA
GeneSlc26a2Authority13521Mapping file id13521 NCBI fileEvidenceIEA
GeneSlc26a3Authority13487Mapping file id13487 NCBI fileEvidenceIEA
GeneSlc26a4Authority23985Mapping file id23985 NCBI fileEvidenceIEA
GeneSlc26a6Authority171429Mapping file id171429 NCBI fileEvidenceIEA
GeneSlc26a7Authority208890Mapping file id208890 NCBI fileEvidenceIEA
GeneSlc26a9Authority320718Mapping file id320718 NCBI fileEvidenceIEA
GeneSlc34a1Authority20505Mapping file idENSMUSG00000021490 Ensembl fileEvidenceIEA
GeneSlc34a2Authority20531Mapping file id20531 NCBI fileEvidenceIEA
GeneSlc34a3Authority142681Mapping file id142681 NCBI fileEvidenceIEA
GeneSlc4a1Authority20533Mapping file id20533 NCBI fileEvidenceIEA
GeneSlc4a10Authority94229Mapping file id94229 NCBI fileEvidenceIEA
GeneSlc4a2Authority20535Mapping file id20535 NCBI fileEvidenceIEA
GeneSlc4a3Authority20536Mapping file id20536 NCBI fileEvidenceIEA
GeneSlc4a4Authority54403Mapping file id54403 NCBI fileEvidenceIEA
GeneSlc4a5Authority232156Mapping file idENSMUSG00000068323 Ensembl fileEvidenceIEA
GeneSlc4a7Authority218756Mapping file idENSMUSG00000021733 Ensembl fileEvidenceIEA
GeneSlc4a8Authority59033Mapping file id59033 NCBI fileEvidenceIEA
GeneSlc4a9Authority240215Mapping file id240215 NCBI fileEvidenceIEA
GeneSlc5a5Authority114479Mapping file idENSMUSG00000000792 Ensembl fileEvidenceIEA
GeneSlc5a8Authority216225Mapping file id216225 NCBI fileEvidenceIEA

Evidence codes on this page: IEA, as the mapping file writes them; a row carrying two was written twice by the file, once under each. The mapping file id says which file placed the gene: an NCBI Gene id from NCBI2Reactome_All_Levels.txt, an Ensembl gene id from Ensembl2Reactome_All_Levels.txt. The two files can disagree about a code, so a row's codes are the one file's view. Measured by this site's build over this release on 2026-09-09: the two files disagree on none of the 87,729 mouse pairs both place.

  • Reactome mapping files, the mouse rows for this pathway · Reactome release 97 · read · Reactome downloads"NCBI2Reactome_All_Levels.txt" and "Ensembl2Reactome_All_Levels.txt", Reactome, release 97, https://reactome.org/download-data/ (date of access 2026-09-09). Data CC0; attribution encouraged.

03The hierarchy

Parents and children in this release's hierarchy

Reactome's hierarchy is a graph rather than a tree: a pathway can sit under more than one parent, and the gene counts are each pathway's own placements at every level under it, so a parent's count is not the sum of its children's.

  • Reactome, the mouse pathway list and hierarchy relationship file · Reactome release 97 · read · Reactome downloads"ReactomePathways.txt" and "ReactomePathwaysRelation.txt", Reactome, release 97, https://reactome.org/download-data/ (date of access 2026-09-09). Data CC0; attribution encouraged.