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Pathway Human Homo sapiens

SLC-mediated transport of inorganic anions

R-HSA-9958790 in Reactome release 97: under SLC-mediated transmembrane transport, with 35 genes placed in it by the mapping files and 5 child pathways in the hierarchy.

The same number in the other species

Reactome writes the mouse and rat events it infers from a human pathway under the human number with the species token. A door opens only where that species' own list in this release holds the id: R-MMU-9958790 (mouse), R-RNO-9958790 (rat). Whether the event was inferred from this one is what the record says.

01The record

Reactome's own record of this pathway

What this tells you

The pathway list, the hierarchy and the genes on this page are read from the files Reactome publishes for Reactome release 97, built into this site on 2026-09-09: the pathway list, the hierarchy relationship file and the two gene mapping files. The record card is the one live read, Reactome's own record of this pathway.

Reactome's download page describes the mapping files: Mapping files link the source database identifier to the lowest level pathway diagram or subset of the pathway, all levels of the pathway hierarchy or database identifier to all reactions. [R13] The gene list here is the all-levels mapping of NCBI Gene ids, filled from the all-levels mapping of Ensembl ids where the NCBI file has no row for a gene; each row names which file it came from by the shape of its source id. Each row carries the evidence codes the file writes for it, as written and unranked, and both where the file writes both; no page of Reactome's documentation the survey read defines the codes, so this page does not expand them. A gene id the identity files do not name is kept as the source's own id with no door rather than turned into a symbol.

On citing what a search finds, Reactome says: It should be remembered that while we strive to contain the most current and accurate data, Reactome should not be used in citations where other primary sources of information are available. [R12] The record card prints the literature Reactome attaches to a curated pathway for that reason. The data are public domain: All data in the Reactome database and files derived from that data are licensed under the Creative Commons Public Domain Dedication (CC0). User may copy, modify, and distribute these data, even for commercial purposes, without asking for permission. Attribution is encouraged but not required. [R10] The pathway illustrations are licensed apart, under CC BY 4.0, and none is shown here.

A gene on this list is one Reactome places in this pathway in this release, and that is all the row says: it does not say the gene is expressed in a tissue or associated with a disease, which are the other two explorers' questions, read from other sources. Reactome's papers of record are [R01] [R02].

  1. [R01] Ragueneau E, Gong C, Sinquin P, Sevilla C, Beavers D, Grentner A, et al. (2026). The Reactome Knowledgebase 2026. Nucleic Acids Research 54:D673-D681. PMID 41251150, doi 10.1093/nar/gkaf1223.
  2. [R02] Milacic M, Beavers D, Conley P, Gong C, Gillespie M, Griss J, et al. (2024). The Reactome Pathway Knowledgebase 2024. Nucleic Acids Research 52:D672-D678. PMID 37941124, doi 10.1093/nar/gkad1025.
  3. [R10] Reactome, reactome.org. License Agreement. https://reactome.org/license, read 2026-09-09.
  4. [R12] Reactome, reactome.org. Citing us. https://reactome.org/cite, read 2026-09-09.
  5. [R13] Reactome, reactome.org. Download. https://reactome.org/download-data, read 2026-09-09.
Reading this pathway's record from Reactome (the pathway record).Still reading. A first read of a pathway can take a while; this page waits up to 35 seconds for it, and its scripts then bring in the panel, or a line saying what did not arrive.

02The genes

Genes Reactome places in this human pathway

The mapping files place 35 genes in this human pathway; showing 1 to 35, in pages of 100, sorted by symbol for reading. The order carries no ranking.

Genes Reactome places in this human pathway, page 1 of 1
GeneAHCYL2AuthorityHGNC:22204Mapping file id23382 NCBI fileEvidenceTAS
GeneSLC12A1AuthorityHGNC:10910Mapping file id6557 NCBI fileEvidenceTAS
GeneSLC12A2AuthorityHGNC:10911Mapping file id6558 NCBI fileEvidenceTAS
GeneSLC12A3AuthorityHGNC:10912Mapping file id6559 NCBI fileEvidenceTAS
GeneSLC12A4AuthorityHGNC:10913Mapping file id6560 NCBI fileEvidenceTAS
GeneSLC12A5AuthorityHGNC:13818Mapping file id57468 NCBI fileEvidenceTAS
GeneSLC12A6AuthorityHGNC:10914Mapping file id9990 NCBI fileEvidenceTAS
GeneSLC12A7AuthorityHGNC:10915Mapping file id10723 NCBI fileEvidenceTAS
GeneSLC13A1AuthorityHGNC:10916Mapping file id6561 NCBI fileEvidenceTAS
GeneSLC13A4AuthorityHGNC:15827Mapping file id26266 NCBI fileEvidenceTAS
GeneSLC17A1AuthorityHGNC:10929Mapping file id6568 NCBI fileEvidenceTAS
GeneSLC20A1AuthorityHGNC:10946Mapping file id6574 NCBI fileEvidenceTAS
GeneSLC20A2AuthorityHGNC:10947Mapping file id6575 NCBI fileEvidenceTAS
GeneSLC26A1AuthorityHGNC:10993Mapping file id10861 NCBI fileEvidenceTAS
GeneSLC26A11AuthorityHGNC:14471Mapping file id284129 NCBI fileEvidenceTAS
GeneSLC26A2AuthorityHGNC:10994Mapping file id1836 NCBI fileEvidenceTAS
GeneSLC26A3AuthorityHGNC:3018Mapping file id1811 NCBI fileEvidenceTAS
GeneSLC26A4AuthorityHGNC:8818Mapping file id5172 NCBI fileEvidenceTAS
GeneSLC26A6AuthorityHGNC:14472Mapping file id65010 NCBI fileEvidenceTAS
GeneSLC26A7AuthorityHGNC:14467Mapping file id115111 NCBI fileEvidenceTAS
GeneSLC26A9AuthorityHGNC:14469Mapping file id115019 NCBI fileEvidenceTAS
GeneSLC34A1AuthorityHGNC:11019Mapping file id6569 NCBI fileEvidenceTAS
GeneSLC34A2AuthorityHGNC:11020Mapping file id10568 NCBI fileEvidenceTAS
GeneSLC34A3AuthorityHGNC:20305Mapping file id142680 NCBI fileEvidenceTAS
GeneSLC4A1AuthorityHGNC:11027Mapping file id6521 NCBI fileEvidenceTAS
GeneSLC4A10AuthorityHGNC:13811Mapping file id57282 NCBI fileEvidenceTAS
GeneSLC4A2AuthorityHGNC:11028Mapping file id6522 NCBI fileEvidenceTAS
GeneSLC4A3AuthorityHGNC:11029Mapping file id6508 NCBI fileEvidenceTAS
GeneSLC4A4AuthorityHGNC:11030Mapping file id8671 NCBI fileEvidenceTAS
GeneSLC4A5AuthorityHGNC:18168Mapping file id57835 NCBI fileEvidenceTAS
GeneSLC4A7AuthorityHGNC:11033Mapping file id9497 NCBI fileEvidenceTAS
GeneSLC4A8AuthorityHGNC:11034Mapping file id9498 NCBI fileEvidenceTAS
GeneSLC4A9AuthorityHGNC:11035Mapping file id83697 NCBI fileEvidenceTAS
GeneSLC5A5AuthorityHGNC:11040Mapping file id6528 NCBI fileEvidenceTAS
GeneSLC5A8AuthorityHGNC:19119Mapping file id160728 NCBI fileEvidenceTAS

Evidence codes on this page: TAS, as the mapping file writes them; a row carrying two was written twice by the file, once under each. The mapping file id says which file placed the gene: an NCBI Gene id from NCBI2Reactome_All_Levels.txt, an Ensembl gene id from Ensembl2Reactome_All_Levels.txt. The two files can disagree about a code, so a row's codes are the one file's view. Measured by this site's build over this release on 2026-09-09: of the 138,908 human pathway-gene pairs both files place, 207 (0.149 per cent, over 47 genes) carry TAS in the Ensembl file where the NCBI rows carry IEA alone.

  • Reactome mapping files, the human rows for this pathway · Reactome release 97 · read · Reactome downloads"NCBI2Reactome_All_Levels.txt" and "Ensembl2Reactome_All_Levels.txt", Reactome, release 97, https://reactome.org/download-data/ (date of access 2026-09-09). Data CC0; attribution encouraged.

03The hierarchy

Parents and children in this release's hierarchy

Reactome's hierarchy is a graph rather than a tree: a pathway can sit under more than one parent, and the gene counts are each pathway's own placements at every level under it, so a parent's count is not the sum of its children's.

  • Reactome, the human pathway list and hierarchy relationship file · Reactome release 97 · read · Reactome downloads"ReactomePathways.txt" and "ReactomePathwaysRelation.txt", Reactome, release 97, https://reactome.org/download-data/ (date of access 2026-09-09). Data CC0; attribution encouraged.