Pathway Human Homo sapiens
Phospholipid metabolism
R-HSA-1483257 in Reactome release 97: under Metabolism of lipids, with 212 genes placed in it by the mapping files and 2 child pathways in the hierarchy.
The same number in the other species
Reactome writes the mouse and rat events it infers from a human pathway under the human number with the species token. A door opens only where that species' own list in this release holds the id: R-MMU-1483257 (mouse), R-RNO-1483257 (rat). Whether the event was inferred from this one is what the record says.
01The record
Reactome's own record of this pathway
What this tells you
The pathway list, the hierarchy and the genes on this page are read from the files Reactome publishes for Reactome release 97, built into this site on 2026-09-09: the pathway list, the hierarchy relationship file and the two gene mapping files. The record card is the one live read, Reactome's own record of this pathway.
Reactome's download page describes the mapping files: Mapping files link the source database identifier to the lowest level pathway diagram or subset of the pathway, all levels of the pathway hierarchy or database identifier to all reactions.
[R13] The gene list here is the all-levels mapping of NCBI Gene ids, filled from the all-levels mapping of Ensembl ids where the NCBI file has no row for a gene; each row names which file it came from by the shape of its source id. Each row carries the evidence codes the file writes for it, as written and unranked, and both where the file writes both; no page of Reactome's documentation the survey read defines the codes, so this page does not expand them. A gene id the identity files do not name is kept as the source's own id with no door rather than turned into a symbol.
On citing what a search finds, Reactome says: It should be remembered that while we strive to contain the most current and accurate data, Reactome should not be used in citations where other primary sources of information are available.
[R12] The record card prints the literature Reactome attaches to a curated pathway for that reason. The data are public domain: All data in the Reactome database and files derived from that data are licensed under the Creative Commons Public Domain Dedication (CC0). User may copy, modify, and distribute these data, even for commercial purposes, without asking for permission. Attribution is encouraged but not required.
[R10] The pathway illustrations are licensed apart, under CC BY 4.0, and none is shown here.
A gene on this list is one Reactome places in this pathway in this release, and that is all the row says: it does not say the gene is expressed in a tissue or associated with a disease, which are the other two explorers' questions, read from other sources. Reactome's papers of record are [R01] [R02].
- [R01] Ragueneau E, Gong C, Sinquin P, Sevilla C, Beavers D, Grentner A, et al. (2026). The Reactome Knowledgebase 2026. Nucleic Acids Research 54:D673-D681. PMID 41251150, doi 10.1093/nar/gkaf1223.
- [R02] Milacic M, Beavers D, Conley P, Gong C, Gillespie M, Griss J, et al. (2024). The Reactome Pathway Knowledgebase 2024. Nucleic Acids Research 52:D672-D678. PMID 37941124, doi 10.1093/nar/gkad1025.
- [R10] Reactome, reactome.org. License Agreement. https://reactome.org/license, read 2026-09-09.
- [R12] Reactome, reactome.org. Citing us. https://reactome.org/cite, read 2026-09-09.
- [R13] Reactome, reactome.org. Download. https://reactome.org/download-data, read 2026-09-09.
02The genes
Genes Reactome places in this human pathway
The mapping files place 212 genes in this human pathway; showing 1 to 100, in pages of 100, sorted by symbol for reading. The order carries no ranking.
| Gene | Authority id | Mapping file id | Evidence codes |
|---|---|---|---|
| GeneABHD3 | AuthorityHGNC:18718 | Mapping file id171586 NCBI file | EvidenceTAS |
| GeneABHD4 | AuthorityHGNC:20154 | Mapping file id63874 NCBI file | EvidenceTAS |
| GeneACHE | AuthorityHGNC:108 | Mapping file id43 NCBI file | EvidenceTAS |
| GeneACP6 | AuthorityHGNC:29609 | Mapping file id51205 NCBI file | EvidenceTAS |
| GeneAGK | AuthorityHGNC:21869 | Mapping file id55750 NCBI file | EvidenceTAS |
| GeneAGPAT1 | AuthorityHGNC:324 | Mapping file id10554 NCBI file | EvidenceTAS |
| GeneAGPAT2 | AuthorityHGNC:325 | Mapping file id10555 NCBI file | EvidenceTAS |
| GeneAGPAT3 | AuthorityHGNC:326 | Mapping file id56894 NCBI file | EvidenceTAS |
| GeneAGPAT4 | AuthorityHGNC:20885 | Mapping file id56895 NCBI file | EvidenceTAS |
| GeneAGPAT5 | AuthorityHGNC:20886 | Mapping file id55326 NCBI file | EvidenceTAS |
| GeneALPI | AuthorityHGNC:437 | Mapping file id248 NCBI file | EvidenceTAS |
| GeneARF1 | AuthorityHGNC:652 | Mapping file id375 NCBI file | EvidenceTAS |
| GeneARF3 | AuthorityHGNC:654 | Mapping file id377 NCBI file | EvidenceTAS |
| GeneAWAT2 | AuthorityHGNC:23251 | Mapping file id158835 NCBI file | EvidenceTAS |
| GeneBCHE | AuthorityHGNC:983 | Mapping file id590 NCBI file | EvidenceTAS |
| GeneBMX | AuthorityHGNC:1079 | Mapping file id660 NCBI file | EvidenceTAS |
| GeneCDIPT | AuthorityHGNC:1769 | Mapping file id10423 NCBI file | EvidenceTAS |
| GeneCDS1 | AuthorityHGNC:1800 | Mapping file id1040 NCBI file | EvidenceTAS |
| GeneCDS2 | AuthorityHGNC:1801 | Mapping file id8760 NCBI file | EvidenceTAS |
| GeneCEPT1 | AuthorityHGNC:24289 | Mapping file id10390 NCBI file | EvidenceTAS |
| GeneCHAT | AuthorityHGNC:1912 | Mapping file id1103 NCBI file | EvidenceTAS |
| GeneCHKA | AuthorityHGNC:1937 | Mapping file id1119 NCBI file | EvidenceTAS |
| GeneCHKB | AuthorityHGNC:1938 | Mapping file id1120 NCBI file | EvidenceTAS |
| GeneCHPT1 | AuthorityHGNC:17852 | Mapping file id56994 NCBI file | EvidenceTAS |
| GeneCPNE1 | AuthorityHGNC:2314 | Mapping file id8904 NCBI file | EvidenceTAS |
| GeneCPNE3 | AuthorityHGNC:2316 | Mapping file id8895 NCBI file | EvidenceTAS |
| GeneCPNE6 | AuthorityHGNC:2319 | Mapping file id9362 NCBI file | EvidenceTAS |
| GeneCPNE7 | AuthorityHGNC:2320 | Mapping file id27132 NCBI file | EvidenceTAS |
| GeneCRLS1 | AuthorityHGNC:16148 | Mapping file id54675 NCBI file | EvidenceTAS |
| GeneCSNK2A1 | AuthorityHGNC:2457 | Mapping file id1457 NCBI file | EvidenceTAS |
| GeneCSNK2A2 | AuthorityHGNC:2459 | Mapping file id1459 NCBI file | EvidenceTAS |
| GeneCSNK2B | AuthorityHGNC:2460 | Mapping file id1460 NCBI file | EvidenceTAS |
| GeneDDHD1 | AuthorityHGNC:19714 | Mapping file id80821 NCBI file | EvidenceTAS |
| GeneDDHD2 | AuthorityHGNC:29106 | Mapping file id23259 NCBI file | EvidenceTAS |
| GeneDGAT1 | AuthorityHGNC:2843 | Mapping file id8694 NCBI file | EvidenceTAS |
| GeneDGAT2 | AuthorityHGNC:16940 | Mapping file id84649 NCBI file | EvidenceTAS |
| GeneDGAT2L6 | AuthorityHGNC:23250 | Mapping file id347516 NCBI file | EvidenceTAS |
| GeneENPP6 | AuthorityHGNC:23409 | Mapping file id133121 NCBI file | EvidenceTAS |
| GeneETNK1 | AuthorityHGNC:24649 | Mapping file id55500 NCBI file | EvidenceTAS |
| GeneETNK2 | AuthorityHGNC:25575 | Mapping file id55224 NCBI file | EvidenceTAS |
| GeneETNPPL | AuthorityHGNC:14404 | Mapping file id64850 NCBI file | EvidenceTAS |
| GeneFIG4 | AuthorityHGNC:16873 | Mapping file id9896 NCBI file | EvidenceIEA, TAS |
| GeneGDE1 | AuthorityHGNC:29644 | Mapping file id51573 NCBI file | EvidenceTAS |
| GeneGDPD1 | AuthorityHGNC:20883 | Mapping file id284161 NCBI file | EvidenceIEA |
| GeneGDPD3 | AuthorityHGNC:28638 | Mapping file id79153 NCBI file | EvidenceIEA |
| GeneGDPD5 | AuthorityHGNC:28804 | Mapping file id81544 NCBI file | EvidenceIEA |
| GeneGNPAT | AuthorityHGNC:4416 | Mapping file id8443 NCBI file | EvidenceTAS |
| GeneGPAM | AuthorityHGNC:24865 | Mapping file id57678 NCBI file | EvidenceTAS |
| GeneGPAT2 | AuthorityHGNC:27168 | Mapping file id150763 NCBI file | EvidenceTAS |
| GeneGPAT3 | AuthorityHGNC:28157 | Mapping file id84803 NCBI file | EvidenceTAS |
| GeneGPAT4 | AuthorityHGNC:20880 | Mapping file id137964 NCBI file | EvidenceTAS |
| GeneGPCPD1 | AuthorityHGNC:26957 | Mapping file id56261 NCBI file | EvidenceIEA |
| GeneGPD1 | AuthorityHGNC:4455 | Mapping file id2819 NCBI file | EvidenceTAS |
| GeneGPD1L | AuthorityHGNC:28956 | Mapping file id23171 NCBI file | EvidenceTAS |
| GeneGPD2 | AuthorityHGNC:4456 | Mapping file id2820 NCBI file | EvidenceTAS |
| GeneHADHA | AuthorityHGNC:4801 | Mapping file id3030 NCBI file | EvidenceTAS |
| GeneHADHB | AuthorityHGNC:4803 | Mapping file id3032 NCBI file | EvidenceTAS |
| GeneINPP4A | AuthorityHGNC:6074 | Mapping file id3631 NCBI file | EvidenceTAS |
| GeneINPP4B | AuthorityHGNC:6075 | Mapping file id8821 NCBI file | EvidenceTAS |
| GeneINPP5D | AuthorityHGNC:6079 | Mapping file id3635 NCBI file | EvidenceTAS |
| GeneINPP5E | AuthorityHGNC:21474 | Mapping file id56623 NCBI file | EvidenceTAS |
| GeneINPP5F | AuthorityHGNC:17054 | Mapping file id22876 NCBI file | EvidenceTAS |
| GeneINPP5J | AuthorityHGNC:8956 | Mapping file id27124 NCBI file | EvidenceTAS |
| GeneINPP5K | AuthorityHGNC:33882 | Mapping file id51763 NCBI file | EvidenceTAS |
| GeneINPPL1 | AuthorityHGNC:6080 | Mapping file id3636 NCBI file | EvidenceTAS |
| GeneLCLAT1 | AuthorityHGNC:26756 | Mapping file id253558 NCBI file | EvidenceTAS |
| GeneLIPH | AuthorityHGNC:18483 | Mapping file id200879 NCBI file | EvidenceTAS |
| GeneLIPI | AuthorityHGNC:18821 | Mapping file id149998 NCBI file | EvidenceTAS |
| GeneLPCAT1 | AuthorityHGNC:25718 | Mapping file id79888 NCBI file | EvidenceTAS |
| GeneLPCAT2 | AuthorityHGNC:26032 | Mapping file id54947 NCBI file | EvidenceTAS |
| GeneLPCAT3 | AuthorityHGNC:30244 | Mapping file id10162 NCBI file | EvidenceTAS |
| GeneLPCAT4 | AuthorityHGNC:30059 | Mapping file id254531 NCBI file | EvidenceTAS |
| GeneLPGAT1 | AuthorityHGNC:28985 | Mapping file id9926 NCBI file | EvidenceTAS |
| GeneLPIN1 | AuthorityHGNC:13345 | Mapping file id23175 NCBI file | EvidenceTAS |
| GeneLPIN2 | AuthorityHGNC:14450 | Mapping file id9663 NCBI file | EvidenceTAS |
| GeneLPIN3 | AuthorityHGNC:14451 | Mapping file id64900 NCBI file | EvidenceTAS |
| GeneMBOAT1 | AuthorityHGNC:21579 | Mapping file id154141 NCBI file | EvidenceTAS |
| GeneMBOAT2 | AuthorityHGNC:25193 | Mapping file id129642 NCBI file | EvidenceTAS |
| GeneMBOAT7 | AuthorityHGNC:15505 | Mapping file id79143 NCBI file | EvidenceTAS |
| GeneMFSD2A | AuthorityHGNC:25897 | Mapping file id84879 NCBI file | EvidenceTAS |
| GeneMGLL | AuthorityHGNC:17038 | Mapping file id11343 NCBI file | EvidenceTAS |
| GeneMIGA1 | AuthorityHGNC:24741 | Mapping file id374986 NCBI file | EvidenceTAS |
| GeneMIGA2 | AuthorityHGNC:23621 | Mapping file id84895 NCBI file | EvidenceTAS |
| GeneMTM1 | AuthorityHGNC:7448 | Mapping file id4534 NCBI file | EvidenceTAS |
| GeneMTMR1 | AuthorityHGNC:7449 | Mapping file id8776 NCBI file | EvidenceTAS |
| GeneMTMR10 | AuthorityHGNC:25999 | Mapping file id54893 NCBI file | EvidenceIEA |
| GeneMTMR12 | AuthorityHGNC:18191 | Mapping file id54545 NCBI file | EvidenceTAS |
| GeneMTMR14 | AuthorityHGNC:26190 | Mapping file id64419 NCBI file | EvidenceTAS |
| GeneMTMR2 | AuthorityHGNC:7450 | Mapping file id8898 NCBI file | EvidenceIEA, TAS |
| GeneMTMR3 | AuthorityHGNC:7451 | Mapping file id8897 NCBI file | EvidenceTAS |
| GeneMTMR4 | AuthorityHGNC:7452 | Mapping file id9110 NCBI file | EvidenceTAS |
| GeneMTMR6 | AuthorityHGNC:7453 | Mapping file id9107 NCBI file | EvidenceTAS |
| GeneMTMR7 | AuthorityHGNC:7454 | Mapping file id9108 NCBI file | EvidenceIEA, TAS |
| GeneMTMR8 | AuthorityHGNC:16825 | Mapping file id55613 NCBI file | EvidenceTAS |
| GeneMTMR9 | AuthorityHGNC:14596 | Mapping file id66036 NCBI file | EvidenceIEA, TAS |
| GeneOCRL | AuthorityHGNC:8108 | Mapping file id4952 NCBI file | EvidenceTAS |
| GeneOSBPL10 | AuthorityHGNC:16395 | Mapping file id114884 NCBI file | EvidenceTAS |
| GeneOSBPL5 | AuthorityHGNC:16392 | Mapping file id114879 NCBI file | EvidenceTAS |
| GeneOSBPL8 | AuthorityHGNC:16396 | Mapping file id114882 NCBI file | EvidenceTAS |
| GenePCTP | AuthorityHGNC:8752 | Mapping file id58488 NCBI file | EvidenceTAS |
Evidence codes on this page: IEA, TAS, as the mapping file writes them; a row carrying two was written twice by the file, once under each. The mapping file id says which file placed the gene: an NCBI Gene id from NCBI2Reactome_All_Levels.txt, an Ensembl gene id from Ensembl2Reactome_All_Levels.txt. The two files can disagree about a code, so a row's codes are the one file's view. Measured by this site's build over this release on 2026-09-09: of the 138,908 human pathway-gene pairs both files place, 207 (0.149 per cent, over 47 genes) carry TAS in the Ensembl file where the NCBI rows carry IEA alone.
- Reactome mapping files, the human rows for this pathway · Reactome release 97 · read · Reactome downloads"NCBI2Reactome_All_Levels.txt" and "Ensembl2Reactome_All_Levels.txt", Reactome, release 97, https://reactome.org/download-data/ (date of access 2026-09-09). Data CC0; attribution encouraged.
03The hierarchy
Parents and children in this release's hierarchy
Reactome's hierarchy is a graph rather than a tree: a pathway can sit under more than one parent, and the gene counts are each pathway's own placements at every level under it, so a parent's count is not the sum of its children's.
- Reactome, the human pathway list and hierarchy relationship file · Reactome release 97 · read · Reactome downloads"ReactomePathways.txt" and "ReactomePathwaysRelation.txt", Reactome, release 97, https://reactome.org/download-data/ (date of access 2026-09-09). Data CC0; attribution encouraged.