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Pathway Human Homo sapiens

Glycerophospholipid biosynthesis

R-HSA-1483206 in Reactome release 97: under Phospholipid metabolism, with 129 genes placed in it by the mapping files and 18 child pathways in the hierarchy.

The same number in the other species

Reactome writes the mouse and rat events it infers from a human pathway under the human number with the species token. A door opens only where that species' own list in this release holds the id: R-MMU-1483206 (mouse), R-RNO-1483206 (rat). Whether the event was inferred from this one is what the record says.

01The record

Reactome's own record of this pathway

What this tells you

The pathway list, the hierarchy and the genes on this page are read from the files Reactome publishes for Reactome release 97, built into this site on 2026-09-09: the pathway list, the hierarchy relationship file and the two gene mapping files. The record card is the one live read, Reactome's own record of this pathway.

Reactome's download page describes the mapping files: Mapping files link the source database identifier to the lowest level pathway diagram or subset of the pathway, all levels of the pathway hierarchy or database identifier to all reactions. [R13] The gene list here is the all-levels mapping of NCBI Gene ids, filled from the all-levels mapping of Ensembl ids where the NCBI file has no row for a gene; each row names which file it came from by the shape of its source id. Each row carries the evidence codes the file writes for it, as written and unranked, and both where the file writes both; no page of Reactome's documentation the survey read defines the codes, so this page does not expand them. A gene id the identity files do not name is kept as the source's own id with no door rather than turned into a symbol.

On citing what a search finds, Reactome says: It should be remembered that while we strive to contain the most current and accurate data, Reactome should not be used in citations where other primary sources of information are available. [R12] The record card prints the literature Reactome attaches to a curated pathway for that reason. The data are public domain: All data in the Reactome database and files derived from that data are licensed under the Creative Commons Public Domain Dedication (CC0). User may copy, modify, and distribute these data, even for commercial purposes, without asking for permission. Attribution is encouraged but not required. [R10] The pathway illustrations are licensed apart, under CC BY 4.0, and none is shown here.

A gene on this list is one Reactome places in this pathway in this release, and that is all the row says: it does not say the gene is expressed in a tissue or associated with a disease, which are the other two explorers' questions, read from other sources. Reactome's papers of record are [R01] [R02].

  1. [R01] Ragueneau E, Gong C, Sinquin P, Sevilla C, Beavers D, Grentner A, et al. (2026). The Reactome Knowledgebase 2026. Nucleic Acids Research 54:D673-D681. PMID 41251150, doi 10.1093/nar/gkaf1223.
  2. [R02] Milacic M, Beavers D, Conley P, Gong C, Gillespie M, Griss J, et al. (2024). The Reactome Pathway Knowledgebase 2024. Nucleic Acids Research 52:D672-D678. PMID 37941124, doi 10.1093/nar/gkad1025.
  3. [R10] Reactome, reactome.org. License Agreement. https://reactome.org/license, read 2026-09-09.
  4. [R12] Reactome, reactome.org. Citing us. https://reactome.org/cite, read 2026-09-09.
  5. [R13] Reactome, reactome.org. Download. https://reactome.org/download-data, read 2026-09-09.
Reading this pathway's record from Reactome (the pathway record).Still reading. A first read of a pathway can take a while; this page waits up to 35 seconds for it, and its scripts then bring in the panel, or a line saying what did not arrive.

02The genes

Genes Reactome places in this human pathway

The mapping files place 129 genes in this human pathway; showing 1 to 100, in pages of 100, sorted by symbol for reading. The order carries no ranking.

Genes Reactome places in this human pathway, page 1 of 2
GeneABHD3AuthorityHGNC:18718Mapping file id171586 NCBI fileEvidenceTAS
GeneABHD4AuthorityHGNC:20154Mapping file id63874 NCBI fileEvidenceTAS
GeneACHEAuthorityHGNC:108Mapping file id43 NCBI fileEvidenceTAS
GeneACP6AuthorityHGNC:29609Mapping file id51205 NCBI fileEvidenceTAS
GeneAGKAuthorityHGNC:21869Mapping file id55750 NCBI fileEvidenceTAS
GeneAGPAT1AuthorityHGNC:324Mapping file id10554 NCBI fileEvidenceTAS
GeneAGPAT2AuthorityHGNC:325Mapping file id10555 NCBI fileEvidenceTAS
GeneAGPAT3AuthorityHGNC:326Mapping file id56894 NCBI fileEvidenceTAS
GeneAGPAT4AuthorityHGNC:20885Mapping file id56895 NCBI fileEvidenceTAS
GeneAGPAT5AuthorityHGNC:20886Mapping file id55326 NCBI fileEvidenceTAS
GeneALPIAuthorityHGNC:437Mapping file id248 NCBI fileEvidenceTAS
GeneAWAT2AuthorityHGNC:23251Mapping file id158835 NCBI fileEvidenceTAS
GeneBCHEAuthorityHGNC:983Mapping file id590 NCBI fileEvidenceTAS
GeneCDIPTAuthorityHGNC:1769Mapping file id10423 NCBI fileEvidenceTAS
GeneCDS1AuthorityHGNC:1800Mapping file id1040 NCBI fileEvidenceTAS
GeneCDS2AuthorityHGNC:1801Mapping file id8760 NCBI fileEvidenceTAS
GeneCEPT1AuthorityHGNC:24289Mapping file id10390 NCBI fileEvidenceTAS
GeneCHATAuthorityHGNC:1912Mapping file id1103 NCBI fileEvidenceTAS
GeneCHKAAuthorityHGNC:1937Mapping file id1119 NCBI fileEvidenceTAS
GeneCHKBAuthorityHGNC:1938Mapping file id1120 NCBI fileEvidenceTAS
GeneCHPT1AuthorityHGNC:17852Mapping file id56994 NCBI fileEvidenceTAS
GeneCPNE1AuthorityHGNC:2314Mapping file id8904 NCBI fileEvidenceTAS
GeneCPNE3AuthorityHGNC:2316Mapping file id8895 NCBI fileEvidenceTAS
GeneCPNE6AuthorityHGNC:2319Mapping file id9362 NCBI fileEvidenceTAS
GeneCPNE7AuthorityHGNC:2320Mapping file id27132 NCBI fileEvidenceTAS
GeneCRLS1AuthorityHGNC:16148Mapping file id54675 NCBI fileEvidenceTAS
GeneCSNK2A1AuthorityHGNC:2457Mapping file id1457 NCBI fileEvidenceTAS
GeneCSNK2A2AuthorityHGNC:2459Mapping file id1459 NCBI fileEvidenceTAS
GeneCSNK2BAuthorityHGNC:2460Mapping file id1460 NCBI fileEvidenceTAS
GeneDDHD1AuthorityHGNC:19714Mapping file id80821 NCBI fileEvidenceTAS
GeneDDHD2AuthorityHGNC:29106Mapping file id23259 NCBI fileEvidenceTAS
GeneDGAT1AuthorityHGNC:2843Mapping file id8694 NCBI fileEvidenceTAS
GeneDGAT2AuthorityHGNC:16940Mapping file id84649 NCBI fileEvidenceTAS
GeneDGAT2L6AuthorityHGNC:23250Mapping file id347516 NCBI fileEvidenceTAS
GeneETNK1AuthorityHGNC:24649Mapping file id55500 NCBI fileEvidenceTAS
GeneETNK2AuthorityHGNC:25575Mapping file id55224 NCBI fileEvidenceTAS
GeneETNPPLAuthorityHGNC:14404Mapping file id64850 NCBI fileEvidenceTAS
GeneGNPATAuthorityHGNC:4416Mapping file id8443 NCBI fileEvidenceTAS
GeneGPAMAuthorityHGNC:24865Mapping file id57678 NCBI fileEvidenceTAS
GeneGPAT2AuthorityHGNC:27168Mapping file id150763 NCBI fileEvidenceTAS
GeneGPAT3AuthorityHGNC:28157Mapping file id84803 NCBI fileEvidenceTAS
GeneGPAT4AuthorityHGNC:20880Mapping file id137964 NCBI fileEvidenceTAS
GeneGPCPD1AuthorityHGNC:26957Mapping file id56261 NCBI fileEvidenceIEA
GeneGPD1AuthorityHGNC:4455Mapping file id2819 NCBI fileEvidenceTAS
GeneGPD1LAuthorityHGNC:28956Mapping file id23171 NCBI fileEvidenceTAS
GeneGPD2AuthorityHGNC:4456Mapping file id2820 NCBI fileEvidenceTAS
GeneHADHAAuthorityHGNC:4801Mapping file id3030 NCBI fileEvidenceTAS
GeneHADHBAuthorityHGNC:4803Mapping file id3032 NCBI fileEvidenceTAS
GeneLCLAT1AuthorityHGNC:26756Mapping file id253558 NCBI fileEvidenceTAS
GeneLIPHAuthorityHGNC:18483Mapping file id200879 NCBI fileEvidenceTAS
GeneLIPIAuthorityHGNC:18821Mapping file id149998 NCBI fileEvidenceTAS
GeneLPCAT1AuthorityHGNC:25718Mapping file id79888 NCBI fileEvidenceTAS
GeneLPCAT2AuthorityHGNC:26032Mapping file id54947 NCBI fileEvidenceTAS
GeneLPCAT3AuthorityHGNC:30244Mapping file id10162 NCBI fileEvidenceTAS
GeneLPCAT4AuthorityHGNC:30059Mapping file id254531 NCBI fileEvidenceTAS
GeneLPGAT1AuthorityHGNC:28985Mapping file id9926 NCBI fileEvidenceTAS
GeneLPIN1AuthorityHGNC:13345Mapping file id23175 NCBI fileEvidenceTAS
GeneLPIN2AuthorityHGNC:14450Mapping file id9663 NCBI fileEvidenceTAS
GeneLPIN3AuthorityHGNC:14451Mapping file id64900 NCBI fileEvidenceTAS
GeneMBOAT1AuthorityHGNC:21579Mapping file id154141 NCBI fileEvidenceTAS
GeneMBOAT2AuthorityHGNC:25193Mapping file id129642 NCBI fileEvidenceTAS
GeneMBOAT7AuthorityHGNC:15505Mapping file id79143 NCBI fileEvidenceTAS
GeneMFSD2AAuthorityHGNC:25897Mapping file id84879 NCBI fileEvidenceTAS
GeneMGLLAuthorityHGNC:17038Mapping file id11343 NCBI fileEvidenceTAS
GeneMIGA1AuthorityHGNC:24741Mapping file id374986 NCBI fileEvidenceTAS
GeneMIGA2AuthorityHGNC:23621Mapping file id84895 NCBI fileEvidenceTAS
GeneOSBPL10AuthorityHGNC:16395Mapping file id114884 NCBI fileEvidenceTAS
GeneOSBPL5AuthorityHGNC:16392Mapping file id114879 NCBI fileEvidenceTAS
GeneOSBPL8AuthorityHGNC:16396Mapping file id114882 NCBI fileEvidenceTAS
GenePCTPAuthorityHGNC:8752Mapping file id58488 NCBI fileEvidenceTAS
GenePCYT1AAuthorityHGNC:8754Mapping file id5130 NCBI fileEvidenceTAS
GenePCYT1BAuthorityHGNC:8755Mapping file id9468 NCBI fileEvidenceTAS
GenePCYT2AuthorityHGNC:8756Mapping file id5833 NCBI fileEvidenceTAS
GenePEMTAuthorityHGNC:8830Mapping file id10400 NCBI fileEvidenceTAS
GenePGPAuthorityHGNC:8909Mapping file id283871 NCBI fileEvidenceTAS
GenePGS1AuthorityHGNC:30029Mapping file id9489 NCBI fileEvidenceIEA
GenePHOSPHO1AuthorityHGNC:16815Mapping file id162466 NCBI fileEvidenceTAS
GenePISDAuthorityHGNC:8999Mapping file id23761 NCBI fileEvidenceIEA
GenePITPNBAuthorityHGNC:9002Mapping file id23760 NCBI fileEvidenceTAS
GenePITPNM1AuthorityHGNC:9003Mapping file id9600 NCBI fileEvidenceTAS
GenePITPNM2AuthorityHGNC:21044Mapping file id57605 NCBI fileEvidenceTAS
GenePITPNM3AuthorityHGNC:21043Mapping file id83394 NCBI fileEvidenceTAS
GenePLA1AAuthorityHGNC:17661Mapping file id51365 NCBI fileEvidenceTAS
GenePLA2G10AuthorityHGNC:9029Mapping file id8399 NCBI fileEvidenceTAS
GenePLA2G12AAuthorityHGNC:18554Mapping file id81579 NCBI fileEvidenceTAS
GenePLA2G15AuthorityHGNC:17163Mapping file id23659 NCBI fileEvidenceTAS
GenePLA2G1BAuthorityHGNC:9030Mapping file id5319 NCBI fileEvidenceTAS
GenePLA2G2AAuthorityHGNC:9031Mapping file id5320 NCBI fileEvidenceTAS
GenePLA2G2DAuthorityHGNC:9033Mapping file id26279 NCBI fileEvidenceTAS
GenePLA2G2EAuthorityHGNC:13414Mapping file id30814 NCBI fileEvidenceTAS
GenePLA2G2FAuthorityHGNC:30040Mapping file id64600 NCBI fileEvidenceTAS
GenePLA2G3AuthorityHGNC:17934Mapping file id50487 NCBI fileEvidenceTAS
GenePLA2G4AAuthorityHGNC:9035Mapping file id5321 NCBI fileEvidenceTAS
GenePLA2G4BAuthorityHGNC:9036Mapping file id100137049 NCBI fileEvidenceTAS
GenePLA2G4CAuthorityHGNC:9037Mapping file id8605 NCBI fileEvidenceTAS
GenePLA2G4DAuthorityHGNC:30038Mapping file id283748 NCBI fileEvidenceTAS
GenePLA2G4EAuthorityHGNC:24791Mapping file id123745 NCBI fileEvidenceTAS
GenePLA2G4FAuthorityHGNC:27396Mapping file id255189 NCBI fileEvidenceTAS
GenePLA2G5AuthorityHGNC:9038Mapping file id5322 NCBI fileEvidenceTAS
GenePLA2G6AuthorityHGNC:9039Mapping file id8398 NCBI fileEvidenceIEA, TAS

Evidence codes on this page: IEA, TAS, as the mapping file writes them; a row carrying two was written twice by the file, once under each. The mapping file id says which file placed the gene: an NCBI Gene id from NCBI2Reactome_All_Levels.txt, an Ensembl gene id from Ensembl2Reactome_All_Levels.txt. The two files can disagree about a code, so a row's codes are the one file's view. Measured by this site's build over this release on 2026-09-09: of the 138,908 human pathway-gene pairs both files place, 207 (0.149 per cent, over 47 genes) carry TAS in the Ensembl file where the NCBI rows carry IEA alone.

  • Reactome mapping files, the human rows for this pathway · Reactome release 97 · read · Reactome downloads"NCBI2Reactome_All_Levels.txt" and "Ensembl2Reactome_All_Levels.txt", Reactome, release 97, https://reactome.org/download-data/ (date of access 2026-09-09). Data CC0; attribution encouraged.

03The hierarchy

Parents and children in this release's hierarchy