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Pathway Human Homo sapiens

Intra-Golgi and retrograde Golgi-to-ER traffic

R-HSA-6811442 in Reactome release 97: under Membrane Trafficking, with 203 genes placed in it by the mapping files and 3 child pathways in the hierarchy.

The same number in the other species

Reactome writes the mouse and rat events it infers from a human pathway under the human number with the species token. A door opens only where that species' own list in this release holds the id: R-MMU-6811442 (mouse), R-RNO-6811442 (rat). Whether the event was inferred from this one is what the record says.

01The record

Reactome's own record of this pathway

What this tells you

The pathway list, the hierarchy and the genes on this page are read from the files Reactome publishes for Reactome release 97, built into this site on 2026-09-09: the pathway list, the hierarchy relationship file and the two gene mapping files. The record card is the one live read, Reactome's own record of this pathway.

Reactome's download page describes the mapping files: Mapping files link the source database identifier to the lowest level pathway diagram or subset of the pathway, all levels of the pathway hierarchy or database identifier to all reactions. [R13] The gene list here is the all-levels mapping of NCBI Gene ids, filled from the all-levels mapping of Ensembl ids where the NCBI file has no row for a gene; each row names which file it came from by the shape of its source id. Each row carries the evidence codes the file writes for it, as written and unranked, and both where the file writes both; no page of Reactome's documentation the survey read defines the codes, so this page does not expand them. A gene id the identity files do not name is kept as the source's own id with no door rather than turned into a symbol.

On citing what a search finds, Reactome says: It should be remembered that while we strive to contain the most current and accurate data, Reactome should not be used in citations where other primary sources of information are available. [R12] The record card prints the literature Reactome attaches to a curated pathway for that reason. The data are public domain: All data in the Reactome database and files derived from that data are licensed under the Creative Commons Public Domain Dedication (CC0). User may copy, modify, and distribute these data, even for commercial purposes, without asking for permission. Attribution is encouraged but not required. [R10] The pathway illustrations are licensed apart, under CC BY 4.0, and none is shown here.

A gene on this list is one Reactome places in this pathway in this release, and that is all the row says: it does not say the gene is expressed in a tissue or associated with a disease, which are the other two explorers' questions, read from other sources. Reactome's papers of record are [R01] [R02].

  1. [R01] Ragueneau E, Gong C, Sinquin P, Sevilla C, Beavers D, Grentner A, et al. (2026). The Reactome Knowledgebase 2026. Nucleic Acids Research 54:D673-D681. PMID 41251150, doi 10.1093/nar/gkaf1223.
  2. [R02] Milacic M, Beavers D, Conley P, Gong C, Gillespie M, Griss J, et al. (2024). The Reactome Pathway Knowledgebase 2024. Nucleic Acids Research 52:D672-D678. PMID 37941124, doi 10.1093/nar/gkad1025.
  3. [R10] Reactome, reactome.org. License Agreement. https://reactome.org/license, read 2026-09-09.
  4. [R12] Reactome, reactome.org. Citing us. https://reactome.org/cite, read 2026-09-09.
  5. [R13] Reactome, reactome.org. Download. https://reactome.org/download-data, read 2026-09-09.
Reading this pathway's record from Reactome (the pathway record).Still reading. A first read of a pathway can take a while; this page waits up to 35 seconds for it, and its scripts then bring in the panel, or a line saying what did not arrive.

02The genes

Genes Reactome places in this human pathway

The mapping files place 203 genes in this human pathway; showing 101 to 200, in pages of 100, sorted by symbol for reading. The order carries no ranking.

Genes Reactome places in this human pathway, page 2 of 3
GeneKIF4AAuthorityHGNC:13339Mapping file id24137 NCBI fileEvidenceTAS
GeneKIF4BAuthorityHGNC:6322Mapping file id285643 NCBI fileEvidenceTAS
GeneKIF5AAuthorityHGNC:6323Mapping file id3798 NCBI fileEvidenceTAS
GeneKIF5BAuthorityHGNC:6324Mapping file id3799 NCBI fileEvidenceTAS
GeneKIF6AuthorityHGNC:21202Mapping file id221458 NCBI fileEvidenceTAS
GeneKIF9AuthorityHGNC:16666Mapping file id64147 NCBI fileEvidenceTAS
GeneKIFAP3AuthorityHGNC:17060Mapping file id22920 NCBI fileEvidenceTAS
GeneKIFC1AuthorityHGNC:6389Mapping file id3833 NCBI fileEvidenceTAS
GeneKIFC2AuthorityHGNC:29530Mapping file id90990 NCBI fileEvidenceTAS
GeneKLC1AuthorityHGNC:6387Mapping file id3831 NCBI fileEvidenceTAS
GeneKLC2AuthorityHGNC:20716Mapping file id64837 NCBI fileEvidenceTAS
GeneKLC3AuthorityHGNC:20717Mapping file id147700 NCBI fileEvidenceTAS
GeneKLC4AuthorityHGNC:21624Mapping file id89953 NCBI fileEvidenceTAS
GeneM6PRAuthorityHGNC:6752Mapping file id4074 NCBI fileEvidenceTAS
GeneMAN1A1AuthorityHGNC:6821Mapping file id4121 NCBI fileEvidenceTAS
GeneMAN1A2AuthorityHGNC:6822Mapping file id10905 NCBI fileEvidenceTAS
GeneMAN1C1AuthorityHGNC:19080Mapping file id57134 NCBI fileEvidenceTAS
GeneMAN2A1AuthorityHGNC:6824Mapping file id4124 NCBI fileEvidenceTAS
GeneMAN2A2AuthorityHGNC:6825Mapping file id4122 NCBI fileEvidenceTAS
GeneNAA30AuthorityHGNC:19844Mapping file id122830 NCBI fileEvidenceIEA
GeneNAA35AuthorityHGNC:24340Mapping file id60560 NCBI fileEvidenceIEA
GeneNAA38AuthorityHGNC:28212Mapping file id84316 NCBI fileEvidenceIEA
GeneNAPAAuthorityHGNC:7641Mapping file id8775 NCBI fileEvidenceTAS
GeneNAPBAuthorityHGNC:15751Mapping file id63908 NCBI fileEvidenceTAS
GeneNAPGAuthorityHGNC:7642Mapping file id8774 NCBI fileEvidenceTAS
GeneNBASAuthorityHGNC:15625Mapping file id51594 NCBI fileEvidenceTAS
GeneNSFAuthorityHGNC:8016Mapping file id4905 NCBI fileEvidenceTAS
GenePAFAH1B1AuthorityHGNC:8574Mapping file id5048 NCBI fileEvidenceTAS
GenePAFAH1B2AuthorityHGNC:8575Mapping file id5049 NCBI fileEvidenceTAS
GenePAFAH1B3AuthorityHGNC:8576Mapping file id5050 NCBI fileEvidenceTAS
GenePLA2G4AAuthorityHGNC:9035Mapping file id5321 NCBI fileEvidenceTAS
GenePLA2G6AuthorityHGNC:9039Mapping file id8398 NCBI fileEvidenceTAS
GenePLIN3AuthorityHGNC:16893Mapping file id10226 NCBI fileEvidenceTAS
GeneRAB18AuthorityHGNC:14244Mapping file id22931 NCBI fileEvidenceTAS
GeneRAB1AAuthorityHGNC:9758Mapping file id5861 NCBI fileEvidenceTAS
GeneRAB1BAuthorityHGNC:18370Mapping file id81876 NCBI fileEvidenceTAS
GeneRAB30AuthorityHGNC:9770Mapping file id27314 NCBI fileEvidenceTAS
GeneRAB33BAuthorityHGNC:16075Mapping file id83452 NCBI fileEvidenceTAS
GeneRAB36AuthorityHGNC:9775Mapping file id9609 NCBI fileEvidenceTAS
GeneRAB39AAuthorityHGNC:16521Mapping file id54734 NCBI fileEvidenceTAS
GeneRAB3GAP1AuthorityHGNC:17063Mapping file id22930 NCBI fileEvidenceTAS
GeneRAB3GAP2AuthorityHGNC:17168Mapping file id25782 NCBI fileEvidenceTAS
GeneRAB41AuthorityHGNC:18293Mapping file id347517 NCBI fileEvidenceTAS
GeneRAB43AuthorityHGNC:19983Mapping file id339122 NCBI fileEvidenceTAS
GeneRAB6AAuthorityHGNC:9786Mapping file id5870 NCBI fileEvidenceTAS
GeneRAB6BAuthorityHGNC:14902Mapping file id51560 NCBI fileEvidenceTAS
GeneRAB9AAuthorityHGNC:9792Mapping file id9367 NCBI fileEvidenceTAS
GeneRAB9BAuthorityHGNC:14090Mapping file id51209 NCBI fileEvidenceTAS
GeneRABEPKAuthorityHGNC:16896Mapping file id10244 NCBI fileEvidenceTAS
GeneRACGAP1AuthorityHGNC:9804Mapping file id29127 NCBI fileEvidenceTAS
GeneRGP1AuthorityHGNC:21965Mapping file id9827 NCBI fileEvidenceTAS
GeneRHOBTB3AuthorityHGNC:18757Mapping file id22836 NCBI fileEvidenceTAS
GeneRIC1AuthorityHGNC:17686Mapping file id57589 NCBI fileEvidenceTAS
GeneRINT1AuthorityHGNC:21876Mapping file id60561 NCBI fileEvidenceTAS
GeneSCOCAuthorityHGNC:20335Mapping file id60592 NCBI fileEvidenceTAS
GeneSEC22BAuthorityHGNC:10700Mapping file id9554 NCBI fileEvidenceTAS
GeneSNAP29AuthorityHGNC:11133Mapping file id9342 NCBI fileEvidenceTAS
GeneSTX10AuthorityHGNC:11428Mapping file id8677 NCBI fileEvidenceTAS
GeneSTX16AuthorityHGNC:11431Mapping file id8675 NCBI fileEvidenceTAS
GeneSTX18AuthorityHGNC:15942Mapping file id53407 NCBI fileEvidenceTAS
GeneSTX5AuthorityHGNC:11440Mapping file id6811 NCBI fileEvidenceTAS
GeneSTX6AuthorityHGNC:11441Mapping file id10228 NCBI fileEvidenceTAS
GeneSURF4AuthorityHGNC:11476Mapping file id6836 NCBI fileEvidenceTAS
GeneSYS1AuthorityHGNC:16162Mapping file id90196 NCBI fileEvidenceTAS
GeneTGOLN2AuthorityHGNC:15450Mapping file id10618 NCBI fileEvidenceTAS
GeneTMED10AuthorityHGNC:16998Mapping file id10972 NCBI fileEvidenceTAS
GeneTMED2AuthorityHGNC:16996Mapping file id10959 NCBI fileEvidenceTAS
GeneTMED3AuthorityHGNC:28889Mapping file id23423 NCBI fileEvidenceTAS
GeneTMED7AuthorityHGNC:24253Mapping file id51014 NCBI fileEvidenceTAS
GeneTMED9AuthorityHGNC:24878Mapping file id54732 NCBI fileEvidenceTAS
GeneTMF1AuthorityHGNC:11870Mapping file id7110 NCBI fileEvidenceTAS
GeneTRIP11AuthorityHGNC:12305Mapping file id9321 NCBI fileEvidenceTAS
GeneTUBA1AAuthorityHGNC:20766Mapping file id7846 NCBI fileEvidenceTAS
GeneTUBA1BAuthorityHGNC:18809Mapping file id10376 NCBI fileEvidenceTAS
GeneTUBA1CAuthorityHGNC:20768Mapping file id84790 NCBI fileEvidenceTAS
GeneTUBA3CAuthorityHGNC:12408Mapping file id7278 NCBI fileEvidenceTAS
GeneTUBA3DAuthorityHGNC:24071Mapping file id113457 NCBI fileEvidenceTAS
GeneTUBA3EAuthorityHGNC:20765Mapping file id112714 NCBI fileEvidenceTAS
GeneTUBA4AAuthorityHGNC:12407Mapping file id7277 NCBI fileEvidenceTAS
GeneTUBA4BAuthorityHGNC:18637Mapping file id80086 NCBI fileEvidenceTAS
GeneTUBA8AuthorityHGNC:12410Mapping file id51807 NCBI fileEvidenceTAS
GeneTUBAL3AuthorityHGNC:23534Mapping file id79861 NCBI fileEvidenceTAS
GeneTUBB1AuthorityHGNC:16257Mapping file id81027 NCBI fileEvidenceTAS
GeneTUBB2AAuthorityHGNC:12412Mapping file id7280 NCBI fileEvidenceTAS
GeneTUBB2BAuthorityHGNC:30829Mapping file id347733 NCBI fileEvidenceTAS
GeneTUBB3AuthorityHGNC:20772Mapping file id10381 NCBI fileEvidenceTAS
GeneTUBB4AAuthorityHGNC:20774Mapping file id10382 NCBI fileEvidenceTAS
GeneTUBB4BAuthorityHGNC:20771Mapping file id10383 NCBI fileEvidenceTAS
GeneTUBB6AuthorityHGNC:20776Mapping file id84617 NCBI fileEvidenceTAS
GeneTUBB8AuthorityHGNC:20773Mapping file id347688 NCBI fileEvidenceTAS
GeneTUBB8BAuthorityHGNC:24983Mapping file id260334 NCBI fileEvidenceTAS
GeneUSE1AuthorityHGNC:30882Mapping file id55850 NCBI fileEvidenceTAS
GeneUSP6NLAuthorityHGNC:16858Mapping file id9712 NCBI fileEvidenceTAS
GeneVAMP3AuthorityHGNC:12644Mapping file id9341 NCBI fileEvidenceTAS
GeneVAMP4AuthorityHGNC:12645Mapping file id8674 NCBI fileEvidenceTAS
GeneVPS45AuthorityHGNC:14579Mapping file id11311 NCBI fileEvidenceTAS
GeneVPS51AuthorityHGNC:1172Mapping file id738 NCBI fileEvidenceTAS
GeneVPS52AuthorityHGNC:10518Mapping file id6293 NCBI fileEvidenceTAS
GeneVPS53AuthorityHGNC:25608Mapping file id55275 NCBI fileEvidenceTAS
GeneVPS54AuthorityHGNC:18652Mapping file id51542 NCBI fileEvidenceTAS

Evidence codes on this page: IEA, TAS, as the mapping file writes them; a row carrying two was written twice by the file, once under each. The mapping file id says which file placed the gene: an NCBI Gene id from NCBI2Reactome_All_Levels.txt, an Ensembl gene id from Ensembl2Reactome_All_Levels.txt. The two files can disagree about a code, so a row's codes are the one file's view. Measured by this site's build over this release on 2026-09-09: of the 138,908 human pathway-gene pairs both files place, 207 (0.149 per cent, over 47 genes) carry TAS in the Ensembl file where the NCBI rows carry IEA alone.

  • Reactome mapping files, the human rows for this pathway · Reactome release 97 · read · Reactome downloads"NCBI2Reactome_All_Levels.txt" and "Ensembl2Reactome_All_Levels.txt", Reactome, release 97, https://reactome.org/download-data/ (date of access 2026-09-09). Data CC0; attribution encouraged.

03The hierarchy

Parents and children in this release's hierarchy

Reactome's hierarchy is a graph rather than a tree: a pathway can sit under more than one parent, and the gene counts are each pathway's own placements at every level under it, so a parent's count is not the sum of its children's.

  • Reactome, the human pathway list and hierarchy relationship file · Reactome release 97 · read · Reactome downloads"ReactomePathways.txt" and "ReactomePathwaysRelation.txt", Reactome, release 97, https://reactome.org/download-data/ (date of access 2026-09-09). Data CC0; attribution encouraged.