Pathway Human Homo sapiens
Dengue Virus Infection
R-HSA-9839923 in Reactome release 97: under Viral Infection Pathways, with 404 genes placed in it by the mapping files and 4 child pathways in the hierarchy.
The same number in the other species
Reactome writes the mouse and rat events it infers from a human pathway under the human number with the species token. A door opens only where that species' own list in this release holds the id; neither of the other two lists holds it. Whether the event was inferred from this one is what the record says.
01The record
Reactome's own record of this pathway
What this tells you
The pathway list, the hierarchy and the genes on this page are read from the files Reactome publishes for Reactome release 97, built into this site on 2026-09-09: the pathway list, the hierarchy relationship file and the two gene mapping files. The record card is the one live read, Reactome's own record of this pathway.
Reactome's download page describes the mapping files: Mapping files link the source database identifier to the lowest level pathway diagram or subset of the pathway, all levels of the pathway hierarchy or database identifier to all reactions.
[R13] The gene list here is the all-levels mapping of NCBI Gene ids, filled from the all-levels mapping of Ensembl ids where the NCBI file has no row for a gene; each row names which file it came from by the shape of its source id. Each row carries the evidence codes the file writes for it, as written and unranked, and both where the file writes both; no page of Reactome's documentation the survey read defines the codes, so this page does not expand them. A gene id the identity files do not name is kept as the source's own id with no door rather than turned into a symbol.
On citing what a search finds, Reactome says: It should be remembered that while we strive to contain the most current and accurate data, Reactome should not be used in citations where other primary sources of information are available.
[R12] The record card prints the literature Reactome attaches to a curated pathway for that reason. The data are public domain: All data in the Reactome database and files derived from that data are licensed under the Creative Commons Public Domain Dedication (CC0). User may copy, modify, and distribute these data, even for commercial purposes, without asking for permission. Attribution is encouraged but not required.
[R10] The pathway illustrations are licensed apart, under CC BY 4.0, and none is shown here.
A gene on this list is one Reactome places in this pathway in this release, and that is all the row says: it does not say the gene is expressed in a tissue or associated with a disease, which are the other two explorers' questions, read from other sources. Reactome's papers of record are [R01] [R02].
- [R01] Ragueneau E, Gong C, Sinquin P, Sevilla C, Beavers D, Grentner A, et al. (2026). The Reactome Knowledgebase 2026. Nucleic Acids Research 54:D673-D681. PMID 41251150, doi 10.1093/nar/gkaf1223.
- [R02] Milacic M, Beavers D, Conley P, Gong C, Gillespie M, Griss J, et al. (2024). The Reactome Pathway Knowledgebase 2024. Nucleic Acids Research 52:D672-D678. PMID 37941124, doi 10.1093/nar/gkad1025.
- [R10] Reactome, reactome.org. License Agreement. https://reactome.org/license, read 2026-09-09.
- [R12] Reactome, reactome.org. Citing us. https://reactome.org/cite, read 2026-09-09.
- [R13] Reactome, reactome.org. Download. https://reactome.org/download-data, read 2026-09-09.
02The genes
Genes Reactome places in this human pathway
The mapping files place 404 genes in this human pathway; showing 1 to 100, in pages of 100, sorted by symbol for reading. The order carries no ranking.
| Gene | Authority id | Mapping file id | Evidence codes |
|---|---|---|---|
| GeneACOT2 | AuthorityHGNC:18431 | Mapping file id10965 NCBI file | EvidenceTAS |
| GeneAGRN | AuthorityHGNC:329 | Mapping file id375790 NCBI file | EvidenceTAS |
| GeneALYREF | AuthorityHGNC:19071 | Mapping file id10189 NCBI file | EvidenceTAS |
| GeneAP2A1 | AuthorityHGNC:561 | Mapping file id160 NCBI file | EvidenceTAS |
| GeneAP2A2 | AuthorityHGNC:562 | Mapping file id161 NCBI file | EvidenceTAS |
| GeneAP2B1 | AuthorityHGNC:563 | Mapping file id163 NCBI file | EvidenceTAS |
| GeneAP2M1 | AuthorityHGNC:564 | Mapping file id1173 NCBI file | EvidenceTAS |
| GeneAP2S1 | AuthorityHGNC:565 | Mapping file id1175 NCBI file | EvidenceTAS |
| GeneAPOA1 | AuthorityHGNC:600 | Mapping file id335 NCBI file | EvidenceTAS |
| GeneAQR | AuthorityHGNC:29513 | Mapping file id9716 NCBI file | EvidenceTAS |
| GeneATG14 | AuthorityHGNC:19962 | Mapping file id22863 NCBI file | EvidenceTAS |
| GeneATG7 | AuthorityHGNC:16935 | Mapping file id10533 NCBI file | EvidenceTAS |
| GeneATL2 | AuthorityHGNC:24047 | Mapping file id64225 NCBI file | EvidenceTAS |
| GeneAUP1 | AuthorityHGNC:891 | Mapping file id550 NCBI file | EvidenceTAS |
| GeneAXL | AuthorityHGNC:905 | Mapping file id558 NCBI file | EvidenceTAS |
| GeneBAG2 | AuthorityHGNC:938 | Mapping file id9532 NCBI file | EvidenceTAS |
| GeneBCAS2 | AuthorityHGNC:975 | Mapping file id10286 NCBI file | EvidenceTAS |
| GeneBECN1 | AuthorityHGNC:1034 | Mapping file id8678 NCBI file | EvidenceTAS |
| GeneBTF3 | AuthorityHGNC:1125 | Mapping file id689 NCBI file | EvidenceTAS |
| GeneBUD31 | AuthorityHGNC:29629 | Mapping file id8896 NCBI file | EvidenceTAS |
| GeneC1QA | AuthorityHGNC:1241 | Mapping file id712 NCBI file | EvidenceTAS |
| GeneC1S | AuthorityHGNC:1247 | Mapping file id716 NCBI file | EvidenceTAS |
| GeneC4A | AuthorityHGNC:1323 | Mapping file id720 NCBI file | EvidenceTAS |
| GeneC4A_2 | AuthorityHGNC:58753 | Mapping file idENSG00000227746 Ensembl file | EvidenceTAS |
| GeneC4B | AuthorityHGNC:1324 | Mapping file id721 NCBI file | EvidenceTAS |
| GeneC4B_2 | AuthorityHGNC:42398 | Mapping file id100293534 NCBI file | EvidenceTAS |
| GeneC4BPA | AuthorityHGNC:1325 | Mapping file id722 NCBI file | EvidenceTAS |
| GeneC4BPB | AuthorityHGNC:1328 | Mapping file id725 NCBI file | EvidenceTAS |
| GeneCALR | AuthorityHGNC:1455 | Mapping file id811 NCBI file | EvidenceTAS |
| GeneCAMK2A | AuthorityHGNC:1460 | Mapping file id815 NCBI file | EvidenceTAS |
| GeneCAMK2B | AuthorityHGNC:1461 | Mapping file id816 NCBI file | EvidenceTAS |
| GeneCAMK2D | AuthorityHGNC:1462 | Mapping file id817 NCBI file | EvidenceTAS |
| GeneCAMK2G | AuthorityHGNC:1463 | Mapping file id818 NCBI file | EvidenceTAS |
| GeneCANX | AuthorityHGNC:1473 | Mapping file id821 NCBI file | EvidenceTAS |
| GeneCCAR1 | AuthorityHGNC:24236 | Mapping file id55749 NCBI file | EvidenceTAS |
| GeneCD14 | AuthorityHGNC:1628 | Mapping file id929 NCBI file | EvidenceTAS |
| GeneCD209 | AuthorityHGNC:1641 | Mapping file id30835 NCBI file | EvidenceTAS |
| GeneCD2BP2 | AuthorityHGNC:1656 | Mapping file id10421 NCBI file | EvidenceTAS |
| GeneCD300A | AuthorityHGNC:19319 | Mapping file id11314 NCBI file | EvidenceTAS |
| GeneCD33 | AuthorityHGNC:1659 | Mapping file id945 NCBI file | EvidenceTAS |
| GeneCDC40 | AuthorityHGNC:17350 | Mapping file id51362 NCBI file | EvidenceTAS |
| GeneCDC5L | AuthorityHGNC:1743 | Mapping file id988 NCBI file | EvidenceTAS |
| GeneCDC73 | AuthorityHGNC:16783 | Mapping file id79577 NCBI file | EvidenceTAS |
| GeneCGAS | AuthorityHGNC:21367 | Mapping file id115004 NCBI file | EvidenceTAS |
| GeneCHERP | AuthorityHGNC:16930 | Mapping file id10523 NCBI file | EvidenceTAS |
| GeneCLDN1 | AuthorityHGNC:2032 | Mapping file id9076 NCBI file | EvidenceTAS |
| GeneCLEC5A | AuthorityHGNC:2054 | Mapping file id23601 NCBI file | EvidenceTAS |
| GeneCLINT1 | AuthorityHGNC:23186 | Mapping file id9685 NCBI file | EvidenceTAS |
| GeneCLP1 | AuthorityHGNC:16999 | Mapping file id10978 NCBI file | EvidenceTAS |
| GeneCLU | AuthorityHGNC:2095 | Mapping file id1191 NCBI file | EvidenceTAS |
| GeneCOG1 | AuthorityHGNC:6545 | Mapping file id9382 NCBI file | EvidenceTAS |
| GeneCPSF1 | AuthorityHGNC:2324 | Mapping file id29894 NCBI file | EvidenceTAS |
| GeneCPSF2 | AuthorityHGNC:2325 | Mapping file id53981 NCBI file | EvidenceTAS |
| GeneCPSF3 | AuthorityHGNC:2326 | Mapping file id51692 NCBI file | EvidenceTAS |
| GeneCPSF4 | AuthorityHGNC:2327 | Mapping file id10898 NCBI file | EvidenceTAS |
| GeneCPSF6 | AuthorityHGNC:13871 | Mapping file id11052 NCBI file | EvidenceTAS |
| GeneCPSF7 | AuthorityHGNC:30098 | Mapping file id79869 NCBI file | EvidenceTAS |
| GeneCRNKL1 | AuthorityHGNC:15762 | Mapping file id51340 NCBI file | EvidenceTAS |
| GeneCSTF1 | AuthorityHGNC:2483 | Mapping file id1477 NCBI file | EvidenceTAS |
| GeneCSTF2 | AuthorityHGNC:2484 | Mapping file id1478 NCBI file | EvidenceTAS |
| GeneCSTF2T | AuthorityHGNC:17086 | Mapping file id23283 NCBI file | EvidenceTAS |
| GeneCSTF3 | AuthorityHGNC:2485 | Mapping file id1479 NCBI file | EvidenceTAS |
| GeneCTNNB1 | AuthorityHGNC:2514 | Mapping file id1499 NCBI file | EvidenceTAS |
| GeneCTNNBL1 | AuthorityHGNC:15879 | Mapping file id56259 NCBI file | EvidenceTAS |
| GeneCTR9 | AuthorityHGNC:16850 | Mapping file id9646 NCBI file | EvidenceTAS |
| GeneCWC15 | AuthorityHGNC:26939 | Mapping file id51503 NCBI file | EvidenceTAS |
| GeneCWC22 | AuthorityHGNC:29322 | Mapping file id57703 NCBI file | EvidenceTAS |
| GeneCWC25 | AuthorityHGNC:25989 | Mapping file id54883 NCBI file | EvidenceTAS |
| GeneCWC27 | AuthorityHGNC:10664 | Mapping file id10283 NCBI file | EvidenceTAS |
| GeneDAD1 | AuthorityHGNC:2664 | Mapping file id1603 NCBI file | EvidenceTAS |
| GeneDAXX | AuthorityHGNC:2681 | Mapping file id1616 NCBI file | EvidenceTAS |
| GeneDDOST | AuthorityHGNC:2728 | Mapping file id1650 NCBI file | EvidenceTAS |
| GeneDDX23 | AuthorityHGNC:17347 | Mapping file id9416 NCBI file | EvidenceTAS |
| GeneDDX3X | AuthorityHGNC:2745 | Mapping file id1654 NCBI file | EvidenceTAS |
| GeneDDX42 | AuthorityHGNC:18676 | Mapping file id11325 NCBI file | EvidenceTAS |
| GeneDDX46 | AuthorityHGNC:18681 | Mapping file id9879 NCBI file | EvidenceTAS |
| GeneDDX5 | AuthorityHGNC:2746 | Mapping file id1655 NCBI file | EvidenceTAS |
| GeneDHX15 | AuthorityHGNC:2738 | Mapping file id1665 NCBI file | EvidenceTAS |
| GeneDHX16 | AuthorityHGNC:2739 | Mapping file id8449 NCBI file | EvidenceTAS |
| GeneDHX38 | AuthorityHGNC:17211 | Mapping file id9785 NCBI file | EvidenceTAS |
| GeneDHX9 | AuthorityHGNC:2750 | Mapping file id1660 NCBI file | EvidenceTAS |
| GeneDNAJA2 | AuthorityHGNC:14884 | Mapping file id10294 NCBI file | EvidenceTAS |
| GeneDNAJB11 | AuthorityHGNC:14889 | Mapping file id51726 NCBI file | EvidenceTAS |
| GeneDNAJC10 | AuthorityHGNC:24637 | Mapping file id54431 NCBI file | EvidenceTAS |
| GeneDNAJC3 | AuthorityHGNC:9439 | Mapping file id5611 NCBI file | EvidenceTAS |
| GeneDNAJC8 | AuthorityHGNC:15470 | Mapping file id22826 NCBI file | EvidenceTAS |
| GeneDPM1 | AuthorityHGNC:3005 | Mapping file id8813 NCBI file | EvidenceTAS |
| GeneDPM2 | AuthorityHGNC:3006 | Mapping file id8818 NCBI file | EvidenceTAS |
| GeneDPM3 | AuthorityHGNC:3007 | Mapping file id54344 NCBI file | EvidenceTAS |
| GeneDYNLT1 | AuthorityHGNC:11697 | Mapping file id6993 NCBI file | EvidenceTAS |
| GeneEFTUD2 | AuthorityHGNC:30858 | Mapping file id9343 NCBI file | EvidenceTAS |
| GeneEIF4A1 | AuthorityHGNC:3282 | Mapping file id1973 NCBI file | EvidenceTAS |
| GeneEIF4A2 | AuthorityHGNC:3284 | Mapping file id1974 NCBI file | EvidenceTAS |
| GeneEIF4A3 | AuthorityHGNC:18683 | Mapping file id9775 NCBI file | EvidenceTAS |
| GeneEIF4E | AuthorityHGNC:3287 | Mapping file id1977 NCBI file | EvidenceTAS |
| GeneEIF4E3 | AuthorityHGNC:31837 | Mapping file id317649 NCBI file | EvidenceTAS |
| GeneEIF4G1 | AuthorityHGNC:3296 | Mapping file id1981 NCBI file | EvidenceTAS |
| GeneEIF4G2 | AuthorityHGNC:3297 | Mapping file id1982 NCBI file | EvidenceTAS |
| GeneEIF4G3 | AuthorityHGNC:3298 | Mapping file id8672 NCBI file | EvidenceTAS |
| GeneELAVL1 | AuthorityHGNC:3312 | Mapping file id1994 NCBI file | EvidenceTAS |
Evidence codes on this page: TAS, as the mapping file writes them; a row carrying two was written twice by the file, once under each. The mapping file id says which file placed the gene: an NCBI Gene id from NCBI2Reactome_All_Levels.txt, an Ensembl gene id from Ensembl2Reactome_All_Levels.txt. The two files can disagree about a code, so a row's codes are the one file's view. Measured by this site's build over this release on 2026-09-09: of the 138,908 human pathway-gene pairs both files place, 207 (0.149 per cent, over 47 genes) carry TAS in the Ensembl file where the NCBI rows carry IEA alone.
- Reactome mapping files, the human rows for this pathway · Reactome release 97 · read · Reactome downloads"NCBI2Reactome_All_Levels.txt" and "Ensembl2Reactome_All_Levels.txt", Reactome, release 97, https://reactome.org/download-data/ (date of access 2026-09-09). Data CC0; attribution encouraged.
03The hierarchy
Parents and children in this release's hierarchy
Reactome's hierarchy is a graph rather than a tree: a pathway can sit under more than one parent, and the gene counts are each pathway's own placements at every level under it, so a parent's count is not the sum of its children's.
- Reactome, the human pathway list and hierarchy relationship file · Reactome release 97 · read · Reactome downloads"ReactomePathways.txt" and "ReactomePathwaysRelation.txt", Reactome, release 97, https://reactome.org/download-data/ (date of access 2026-09-09). Data CC0; attribution encouraged.