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Pathway Human Homo sapiens

Dengue Virus Infection

R-HSA-9839923 in Reactome release 97: under Viral Infection Pathways, with 404 genes placed in it by the mapping files and 4 child pathways in the hierarchy.

The same number in the other species

Reactome writes the mouse and rat events it infers from a human pathway under the human number with the species token. A door opens only where that species' own list in this release holds the id; neither of the other two lists holds it. Whether the event was inferred from this one is what the record says.

01The record

Reactome's own record of this pathway

What this tells you

The pathway list, the hierarchy and the genes on this page are read from the files Reactome publishes for Reactome release 97, built into this site on 2026-09-09: the pathway list, the hierarchy relationship file and the two gene mapping files. The record card is the one live read, Reactome's own record of this pathway.

Reactome's download page describes the mapping files: Mapping files link the source database identifier to the lowest level pathway diagram or subset of the pathway, all levels of the pathway hierarchy or database identifier to all reactions. [R13] The gene list here is the all-levels mapping of NCBI Gene ids, filled from the all-levels mapping of Ensembl ids where the NCBI file has no row for a gene; each row names which file it came from by the shape of its source id. Each row carries the evidence codes the file writes for it, as written and unranked, and both where the file writes both; no page of Reactome's documentation the survey read defines the codes, so this page does not expand them. A gene id the identity files do not name is kept as the source's own id with no door rather than turned into a symbol.

On citing what a search finds, Reactome says: It should be remembered that while we strive to contain the most current and accurate data, Reactome should not be used in citations where other primary sources of information are available. [R12] The record card prints the literature Reactome attaches to a curated pathway for that reason. The data are public domain: All data in the Reactome database and files derived from that data are licensed under the Creative Commons Public Domain Dedication (CC0). User may copy, modify, and distribute these data, even for commercial purposes, without asking for permission. Attribution is encouraged but not required. [R10] The pathway illustrations are licensed apart, under CC BY 4.0, and none is shown here.

A gene on this list is one Reactome places in this pathway in this release, and that is all the row says: it does not say the gene is expressed in a tissue or associated with a disease, which are the other two explorers' questions, read from other sources. Reactome's papers of record are [R01] [R02].

  1. [R01] Ragueneau E, Gong C, Sinquin P, Sevilla C, Beavers D, Grentner A, et al. (2026). The Reactome Knowledgebase 2026. Nucleic Acids Research 54:D673-D681. PMID 41251150, doi 10.1093/nar/gkaf1223.
  2. [R02] Milacic M, Beavers D, Conley P, Gong C, Gillespie M, Griss J, et al. (2024). The Reactome Pathway Knowledgebase 2024. Nucleic Acids Research 52:D672-D678. PMID 37941124, doi 10.1093/nar/gkad1025.
  3. [R10] Reactome, reactome.org. License Agreement. https://reactome.org/license, read 2026-09-09.
  4. [R12] Reactome, reactome.org. Citing us. https://reactome.org/cite, read 2026-09-09.
  5. [R13] Reactome, reactome.org. Download. https://reactome.org/download-data, read 2026-09-09.
Reading this pathway's record from Reactome (the pathway record).Still reading. A first read of a pathway can take a while; this page waits up to 35 seconds for it, and its scripts then bring in the panel, or a line saying what did not arrive.

02The genes

Genes Reactome places in this human pathway

The mapping files place 404 genes in this human pathway; showing 101 to 200, in pages of 100, sorted by symbol for reading. The order carries no ranking.

Genes Reactome places in this human pathway, page 2 of 5
GeneELAVL2AuthorityHGNC:3313Mapping file id1993 NCBI fileEvidenceTAS
GeneEMC4AuthorityHGNC:28032Mapping file id51234 NCBI fileEvidenceTAS
GeneEXOC1AuthorityHGNC:30380Mapping file id55763 NCBI fileEvidenceTAS
GeneF2AuthorityHGNC:3535Mapping file id2147 NCBI fileEvidenceTAS
GeneFASNAuthorityHGNC:3594Mapping file id2194 NCBI fileEvidenceTAS
GeneFIP1L1AuthorityHGNC:19124Mapping file id81608 NCBI fileEvidenceTAS
GeneFURINAuthorityHGNC:8568Mapping file id5045 NCBI fileEvidenceTAS
GeneFUSAuthorityHGNC:4010Mapping file id2521 NCBI fileEvidenceTAS
GeneGAS6AuthorityHGNC:4168Mapping file id2621 NCBI fileEvidenceTAS
GeneGBF1AuthorityHGNC:4181Mapping file id8729 NCBI fileEvidenceTAS
GeneGPC1AuthorityHGNC:4449Mapping file id2817 NCBI fileEvidenceTAS
GeneGPC2AuthorityHGNC:4450Mapping file id221914 NCBI fileEvidenceTAS
GeneGPC3AuthorityHGNC:4451Mapping file id2719 NCBI fileEvidenceTAS
GeneGPC4AuthorityHGNC:4452Mapping file id2239 NCBI fileEvidenceTAS
GeneGPC5AuthorityHGNC:4453Mapping file id2262 NCBI fileEvidenceTAS
GeneGPC6AuthorityHGNC:4454Mapping file id10082 NCBI fileEvidenceTAS
GeneGPKOWAuthorityHGNC:30677Mapping file id27238 NCBI fileEvidenceTAS
GeneGRPEL1AuthorityHGNC:19696Mapping file id80273 NCBI fileEvidenceTAS
GeneGTF2F1AuthorityHGNC:4652Mapping file id2962 NCBI fileEvidenceTAS
GeneGTF2F2AuthorityHGNC:4653Mapping file id2963 NCBI fileEvidenceTAS
GeneH2AC1AuthorityHGNC:18729Mapping file id221613 NCBI fileEvidenceTAS
GeneH2AC11AuthorityHGNC:4737Mapping file id8969 NCBI fileEvidenceTAS
GeneH2AC12AuthorityHGNC:13671Mapping file id85235 NCBI fileEvidenceTAS
GeneH2AC13AuthorityHGNC:4725Mapping file id8329 NCBI fileEvidenceTAS
GeneH2AC14AuthorityHGNC:4727Mapping file id8331 NCBI fileEvidenceTAS
GeneH2AC15AuthorityHGNC:4726Mapping file id8330 NCBI fileEvidenceTAS
GeneH2AC16AuthorityHGNC:4730Mapping file id8332 NCBI fileEvidenceTAS
GeneH2AC17AuthorityHGNC:4735Mapping file id8336 NCBI fileEvidenceTAS
GeneH2AC18AuthorityHGNC:4736Mapping file id8337 NCBI fileEvidenceTAS
GeneH2AC19AuthorityHGNC:29668Mapping file id723790 NCBI fileEvidenceTAS
GeneH2AC20AuthorityHGNC:4738Mapping file id8338 NCBI fileEvidenceTAS
GeneH2AC21AuthorityHGNC:20508Mapping file id317772 NCBI fileEvidenceTAS
GeneH2AC25AuthorityHGNC:20507Mapping file id92815 NCBI fileEvidenceTAS
GeneH2AC4AuthorityHGNC:4734Mapping file id8335 NCBI fileEvidenceTAS
GeneH2AC6AuthorityHGNC:4733Mapping file id8334 NCBI fileEvidenceTAS
GeneH2AC7AuthorityHGNC:4729Mapping file id3013 NCBI fileEvidenceTAS
GeneH2AC8AuthorityHGNC:4724Mapping file id3012 NCBI fileEvidenceTAS
GeneH2BC1AuthorityHGNC:18730Mapping file id255626 NCBI fileEvidenceTAS
GeneH2BC10AuthorityHGNC:4756Mapping file id8346 NCBI fileEvidenceTAS
GeneH2BC11AuthorityHGNC:4761Mapping file id8970 NCBI fileEvidenceTAS
GeneH2BC12AuthorityHGNC:13954Mapping file id85236 NCBI fileEvidenceTAS
GeneH2BC13AuthorityHGNC:4748Mapping file id8340 NCBI fileEvidenceTAS
GeneH2BC14AuthorityHGNC:4750Mapping file id8342 NCBI fileEvidenceTAS
GeneH2BC15AuthorityHGNC:4749Mapping file id8341 NCBI fileEvidenceTAS
GeneH2BC17AuthorityHGNC:4758Mapping file id8348 NCBI fileEvidenceTAS
GeneH2BC18AuthorityHGNC:24700Mapping file id440689 NCBI fileEvidenceTAS
GeneH2BC21AuthorityHGNC:4760Mapping file id8349 NCBI fileEvidenceTAS
GeneH2BC26AuthorityHGNC:20514Mapping file id128312 NCBI fileEvidenceTAS
GeneH2BC3AuthorityHGNC:4751Mapping file id3018 NCBI fileEvidenceTAS
GeneH2BC4AuthorityHGNC:4757Mapping file id8347 NCBI fileEvidenceTAS
GeneH2BC5AuthorityHGNC:4747Mapping file id3017 NCBI fileEvidenceTAS
GeneH2BC6AuthorityHGNC:4753Mapping file id8344 NCBI fileEvidenceTAS
GeneH2BC7AuthorityHGNC:4752Mapping file id8343 NCBI fileEvidenceTAS
GeneH2BC8AuthorityHGNC:4746Mapping file id8339 NCBI fileEvidenceTAS
GeneH2BC9AuthorityHGNC:4755Mapping file id8345 NCBI fileEvidenceTAS
GeneH3C1AuthorityHGNC:4766Mapping file id8350 NCBI fileEvidenceTAS
GeneH3C10AuthorityHGNC:4775Mapping file id8357 NCBI fileEvidenceTAS
GeneH3C11AuthorityHGNC:4771Mapping file id8354 NCBI fileEvidenceTAS
GeneH3C12AuthorityHGNC:4774Mapping file id8356 NCBI fileEvidenceTAS
GeneH3C13AuthorityHGNC:25311Mapping file id653604 NCBI fileEvidenceTAS
GeneH3C14AuthorityHGNC:20503Mapping file id126961 NCBI fileEvidenceTAS
GeneH3C15AuthorityHGNC:20505Mapping file id333932 NCBI fileEvidenceTAS
GeneH3C2AuthorityHGNC:4776Mapping file id8358 NCBI fileEvidenceTAS
GeneH3C3AuthorityHGNC:4768Mapping file id8352 NCBI fileEvidenceTAS
GeneH3C4AuthorityHGNC:4767Mapping file id8351 NCBI fileEvidenceTAS
GeneH3C6AuthorityHGNC:4769Mapping file id8353 NCBI fileEvidenceTAS
GeneH3C7AuthorityHGNC:4773Mapping file id8968 NCBI fileEvidenceTAS
GeneH3C8AuthorityHGNC:4772Mapping file id8355 NCBI fileEvidenceTAS
GeneH4C1AuthorityHGNC:4781Mapping file id8359 NCBI fileEvidenceTAS
GeneH4C11AuthorityHGNC:4785Mapping file id8363 NCBI fileEvidenceTAS
GeneH4C12AuthorityHGNC:4784Mapping file id8362 NCBI fileEvidenceTAS
GeneH4C13AuthorityHGNC:4791Mapping file id8368 NCBI fileEvidenceTAS
GeneH4C14AuthorityHGNC:4794Mapping file id8370 NCBI fileEvidenceTAS
GeneH4C15AuthorityHGNC:29607Mapping file id554313 NCBI fileEvidenceTAS
GeneH4C16AuthorityHGNC:20510Mapping file id121504 NCBI fileEvidenceTAS
GeneH4C2AuthorityHGNC:4789Mapping file id8366 NCBI fileEvidenceTAS
GeneH4C3AuthorityHGNC:4787Mapping file id8364 NCBI fileEvidenceTAS
GeneH4C4AuthorityHGNC:4782Mapping file id8360 NCBI fileEvidenceTAS
GeneH4C5AuthorityHGNC:4790Mapping file id8367 NCBI fileEvidenceTAS
GeneH4C6AuthorityHGNC:4783Mapping file id8361 NCBI fileEvidenceTAS
GeneH4C8AuthorityHGNC:4788Mapping file id8365 NCBI fileEvidenceTAS
GeneH4C9AuthorityHGNC:4793Mapping file id8294 NCBI fileEvidenceTAS
GeneHAVCR1AuthorityHGNC:17866Mapping file id26762 NCBI fileEvidenceTAS
GeneHDLBPAuthorityHGNC:4857Mapping file id3069 NCBI fileEvidenceTAS
GeneHNRNPA0AuthorityHGNC:5030Mapping file id10949 NCBI fileEvidenceTAS
GeneHNRNPA1AuthorityHGNC:5031Mapping file id3178 NCBI fileEvidenceTAS
GeneHNRNPA2B1AuthorityHGNC:5033Mapping file id3181 NCBI fileEvidenceTAS
GeneHNRNPA3AuthorityHGNC:24941Mapping file id220988 NCBI fileEvidenceTAS
GeneHNRNPCAuthorityHGNC:5035Mapping file id3183 NCBI fileEvidenceTAS
GeneHNRNPDAuthorityHGNC:5036Mapping file id3184 NCBI fileEvidenceTAS
GeneHNRNPFAuthorityHGNC:5039Mapping file id3185 NCBI fileEvidenceTAS
GeneHNRNPH1AuthorityHGNC:5041Mapping file id3187 NCBI fileEvidenceTAS
GeneHNRNPH2AuthorityHGNC:5042Mapping file id3188 NCBI fileEvidenceTAS
GeneHNRNPKAuthorityHGNC:5044Mapping file id3190 NCBI fileEvidenceTAS
GeneHNRNPLAuthorityHGNC:5045Mapping file id3191 NCBI fileEvidenceTAS
GeneHNRNPMAuthorityHGNC:5046Mapping file id4670 NCBI fileEvidenceTAS
GeneHNRNPRAuthorityHGNC:5047Mapping file id10236 NCBI fileEvidenceTAS
GeneHNRNPUAuthorityHGNC:5048Mapping file id3192 NCBI fileEvidenceTAS
GeneHNRNPUL1AuthorityHGNC:17011Mapping file id11100 NCBI fileEvidenceTAS
GeneHSP90AA1AuthorityHGNC:5253Mapping file id3320 NCBI fileEvidenceTAS

Evidence codes on this page: TAS, as the mapping file writes them; a row carrying two was written twice by the file, once under each. The mapping file id says which file placed the gene: an NCBI Gene id from NCBI2Reactome_All_Levels.txt, an Ensembl gene id from Ensembl2Reactome_All_Levels.txt. The two files can disagree about a code, so a row's codes are the one file's view. Measured by this site's build over this release on 2026-09-09: of the 138,908 human pathway-gene pairs both files place, 207 (0.149 per cent, over 47 genes) carry TAS in the Ensembl file where the NCBI rows carry IEA alone.

  • Reactome mapping files, the human rows for this pathway · Reactome release 97 · read · Reactome downloads"NCBI2Reactome_All_Levels.txt" and "Ensembl2Reactome_All_Levels.txt", Reactome, release 97, https://reactome.org/download-data/ (date of access 2026-09-09). Data CC0; attribution encouraged.

03The hierarchy

Parents and children in this release's hierarchy

Reactome's hierarchy is a graph rather than a tree: a pathway can sit under more than one parent, and the gene counts are each pathway's own placements at every level under it, so a parent's count is not the sum of its children's.

  • Reactome, the human pathway list and hierarchy relationship file · Reactome release 97 · read · Reactome downloads"ReactomePathways.txt" and "ReactomePathwaysRelation.txt", Reactome, release 97, https://reactome.org/download-data/ (date of access 2026-09-09). Data CC0; attribution encouraged.