Pathway Human Homo sapiens
Dengue Virus Infection
R-HSA-9839923 in Reactome release 97: under Viral Infection Pathways, with 404 genes placed in it by the mapping files and 4 child pathways in the hierarchy.
The same number in the other species
Reactome writes the mouse and rat events it infers from a human pathway under the human number with the species token. A door opens only where that species' own list in this release holds the id; neither of the other two lists holds it. Whether the event was inferred from this one is what the record says.
01The record
Reactome's own record of this pathway
What this tells you
The pathway list, the hierarchy and the genes on this page are read from the files Reactome publishes for Reactome release 97, built into this site on 2026-09-09: the pathway list, the hierarchy relationship file and the two gene mapping files. The record card is the one live read, Reactome's own record of this pathway.
Reactome's download page describes the mapping files: Mapping files link the source database identifier to the lowest level pathway diagram or subset of the pathway, all levels of the pathway hierarchy or database identifier to all reactions.
[R13] The gene list here is the all-levels mapping of NCBI Gene ids, filled from the all-levels mapping of Ensembl ids where the NCBI file has no row for a gene; each row names which file it came from by the shape of its source id. Each row carries the evidence codes the file writes for it, as written and unranked, and both where the file writes both; no page of Reactome's documentation the survey read defines the codes, so this page does not expand them. A gene id the identity files do not name is kept as the source's own id with no door rather than turned into a symbol.
On citing what a search finds, Reactome says: It should be remembered that while we strive to contain the most current and accurate data, Reactome should not be used in citations where other primary sources of information are available.
[R12] The record card prints the literature Reactome attaches to a curated pathway for that reason. The data are public domain: All data in the Reactome database and files derived from that data are licensed under the Creative Commons Public Domain Dedication (CC0). User may copy, modify, and distribute these data, even for commercial purposes, without asking for permission. Attribution is encouraged but not required.
[R10] The pathway illustrations are licensed apart, under CC BY 4.0, and none is shown here.
A gene on this list is one Reactome places in this pathway in this release, and that is all the row says: it does not say the gene is expressed in a tissue or associated with a disease, which are the other two explorers' questions, read from other sources. Reactome's papers of record are [R01] [R02].
- [R01] Ragueneau E, Gong C, Sinquin P, Sevilla C, Beavers D, Grentner A, et al. (2026). The Reactome Knowledgebase 2026. Nucleic Acids Research 54:D673-D681. PMID 41251150, doi 10.1093/nar/gkaf1223.
- [R02] Milacic M, Beavers D, Conley P, Gong C, Gillespie M, Griss J, et al. (2024). The Reactome Pathway Knowledgebase 2024. Nucleic Acids Research 52:D672-D678. PMID 37941124, doi 10.1093/nar/gkad1025.
- [R10] Reactome, reactome.org. License Agreement. https://reactome.org/license, read 2026-09-09.
- [R12] Reactome, reactome.org. Citing us. https://reactome.org/cite, read 2026-09-09.
- [R13] Reactome, reactome.org. Download. https://reactome.org/download-data, read 2026-09-09.
02The genes
Genes Reactome places in this human pathway
The mapping files place 404 genes in this human pathway; showing 201 to 300, in pages of 100, sorted by symbol for reading. The order carries no ranking.
| Gene | Authority id | Mapping file id | Evidence codes |
|---|---|---|---|
| GeneHSP90AB1 | AuthorityHGNC:5258 | Mapping file id3326 NCBI file | EvidenceTAS |
| GeneHSPA1A | AuthorityHGNC:5232 | Mapping file id3303 NCBI file | EvidenceTAS |
| GeneHSPA1B | AuthorityHGNC:5233 | Mapping file id3304 NCBI file | EvidenceTAS |
| GeneHSPA5 | AuthorityHGNC:5238 | Mapping file id3309 NCBI file | EvidenceTAS |
| GeneHSPA8 | AuthorityHGNC:5241 | Mapping file id3312 NCBI file | EvidenceTAS |
| GeneHSPG2 | AuthorityHGNC:5273 | Mapping file id3339 NCBI file | EvidenceTAS |
| GeneHYOU1 | AuthorityHGNC:16931 | Mapping file id10525 NCBI file | EvidenceTAS |
| GeneIFIH1 | AuthorityHGNC:18873 | Mapping file id64135 NCBI file | EvidenceTAS |
| GeneIKBKE | AuthorityHGNC:14552 | Mapping file id9641 NCBI file | EvidenceTAS |
| GeneIPO7 | AuthorityHGNC:9852 | Mapping file id10527 NCBI file | EvidenceTAS |
| GeneISY1 | AuthorityHGNC:29201 | Mapping file id57461 NCBI file | EvidenceTAS |
| GeneISY1-RAB43 | AuthorityHGNC:42969 | Mapping file id100534599 NCBI file | EvidenceTAS |
| GeneKDELR1 | AuthorityHGNC:6304 | Mapping file id10945 NCBI file | EvidenceTAS |
| GeneKPNA1 | AuthorityHGNC:6394 | Mapping file id3836 NCBI file | EvidenceIEA, TAS |
| GeneKPNA2 | AuthorityHGNC:6395 | Mapping file id3838 NCBI file | EvidenceIEA, TAS |
| GeneKPNA3 | AuthorityHGNC:6396 | Mapping file id3839 NCBI file | EvidenceIEA, TAS |
| GeneKPNA4 | AuthorityHGNC:6397 | Mapping file id3840 NCBI file | EvidenceIEA, TAS |
| GeneKPNA5 | AuthorityHGNC:6398 | Mapping file id3841 NCBI file | EvidenceIEA, TAS |
| GeneKPNA7 | AuthorityHGNC:21839 | Mapping file id402569 NCBI file | EvidenceIEA, TAS |
| GeneKPNB1 | AuthorityHGNC:6400 | Mapping file id3837 NCBI file | EvidenceIEA, TAS |
| GeneLEO1 | AuthorityHGNC:30401 | Mapping file id123169 NCBI file | EvidenceTAS |
| GeneLY6E | AuthorityHGNC:6727 | Mapping file id4061 NCBI file | EvidenceTAS |
| GeneLY96 | AuthorityHGNC:17156 | Mapping file id23643 NCBI file | EvidenceTAS |
| GeneLYN | AuthorityHGNC:6735 | Mapping file id4067 NCBI file | EvidenceTAS |
| GeneMAGT1 | AuthorityHGNC:28880 | Mapping file id84061 NCBI file | EvidenceTAS |
| GeneMAP1LC3B | AuthorityHGNC:13352 | Mapping file id81631 NCBI file | EvidenceTAS |
| GeneMAPKAP1 | AuthorityHGNC:18752 | Mapping file id79109 NCBI file | EvidenceTAS |
| GeneMAPRE3 | AuthorityHGNC:6892 | Mapping file id22924 NCBI file | EvidenceTAS |
| GeneMAVS | AuthorityHGNC:29233 | Mapping file id57506 NCBI file | EvidenceTAS |
| GeneMBL2 | AuthorityHGNC:6922 | Mapping file id4153 NCBI file | EvidenceTAS |
| GeneMERTK | AuthorityHGNC:7027 | Mapping file id10461 NCBI file | EvidenceTAS |
| GeneMLST8 | AuthorityHGNC:24825 | Mapping file id64223 NCBI file | EvidenceTAS |
| GeneMMP9 | AuthorityHGNC:7176 | Mapping file id4318 NCBI file | EvidenceTAS |
| GeneMRC1 | AuthorityHGNC:7228 | Mapping file id4360 NCBI file | EvidenceTAS |
| GeneMTOR | AuthorityHGNC:3942 | Mapping file id2475 NCBI file | EvidenceTAS |
| GeneNACA | AuthorityHGNC:7629 | Mapping file id4666 NCBI file | EvidenceTAS |
| GeneNCBP1 | AuthorityHGNC:7658 | Mapping file id4686 NCBI file | EvidenceTAS |
| GeneNCBP2 | AuthorityHGNC:7659 | Mapping file id22916 NCBI file | EvidenceTAS |
| GeneNEK2 | AuthorityHGNC:7745 | Mapping file id4751 NCBI file | EvidenceTAS |
| GeneNFKBIA | AuthorityHGNC:7797 | Mapping file id4792 NCBI file | EvidenceTAS |
| GeneNFKBIB | AuthorityHGNC:7798 | Mapping file id4793 NCBI file | EvidenceTAS |
| GeneNMT1 | AuthorityHGNC:7857 | Mapping file id4836 NCBI file | EvidenceTAS |
| GeneNPLOC4 | AuthorityHGNC:18261 | Mapping file id55666 NCBI file | EvidenceTAS |
| GeneNRBP1 | AuthorityHGNC:7993 | Mapping file id29959 NCBI file | EvidenceTAS |
| GeneNUCLEOLIN | AuthorityHGNC:7667 | Mapping file id4691 NCBI file | EvidenceTAS |
| GeneNUDT21 | AuthorityHGNC:13870 | Mapping file id11051 NCBI file | EvidenceTAS |
| GeneOST4 | AuthorityHGNC:32483 | Mapping file id100128731 NCBI file | EvidenceTAS |
| GeneOSTC | AuthorityHGNC:24448 | Mapping file id58505 NCBI file | EvidenceTAS |
| GeneP4HA1 | AuthorityHGNC:8546 | Mapping file id5033 NCBI file | EvidenceTAS |
| GeneP4HA2 | AuthorityHGNC:8547 | Mapping file id8974 NCBI file | EvidenceTAS |
| GeneP4HA3 | AuthorityHGNC:30135 | Mapping file id283208 NCBI file | EvidenceTAS |
| GeneP4HB | AuthorityHGNC:8548 | Mapping file id5034 NCBI file | EvidenceTAS |
| GenePABPC1 | AuthorityHGNC:8554 | Mapping file id26986 NCBI file | EvidenceTAS |
| GenePABPN1 | AuthorityHGNC:8565 | Mapping file id8106 NCBI file | EvidenceTAS |
| GenePAF1 | AuthorityHGNC:25459 | Mapping file id54623 NCBI file | EvidenceTAS |
| GenePAPOLA | AuthorityHGNC:14981 | Mapping file id10914 NCBI file | EvidenceTAS |
| GenePCBP1 | AuthorityHGNC:8647 | Mapping file id5093 NCBI file | EvidenceTAS |
| GenePCBP2 | AuthorityHGNC:8648 | Mapping file id5094 NCBI file | EvidenceTAS |
| GenePCF11 | AuthorityHGNC:30097 | Mapping file id51585 NCBI file | EvidenceTAS |
| GenePDCD6IP | AuthorityHGNC:8766 | Mapping file id10015 NCBI file | EvidenceTAS |
| GenePDIA3 | AuthorityHGNC:4606 | Mapping file id2923 NCBI file | EvidenceTAS |
| GenePEX19 | AuthorityHGNC:9713 | Mapping file id5824 NCBI file | EvidenceTAS |
| GenePHF5A | AuthorityHGNC:18000 | Mapping file id84844 NCBI file | EvidenceTAS |
| GenePIK3C3 | AuthorityHGNC:8974 | Mapping file id5289 NCBI file | EvidenceTAS |
| GenePIK3R1 | AuthorityHGNC:8979 | Mapping file id5295 NCBI file | EvidenceTAS |
| GenePIK3R4 | AuthorityHGNC:8982 | Mapping file id30849 NCBI file | EvidenceTAS |
| GenePLRG1 | AuthorityHGNC:9089 | Mapping file id5356 NCBI file | EvidenceTAS |
| GenePML | AuthorityHGNC:9113 | Mapping file id5371 NCBI file | EvidenceTAS |
| GenePOLR2A | AuthorityHGNC:9187 | Mapping file id5430 NCBI file | EvidenceTAS |
| GenePOLR2B | AuthorityHGNC:9188 | Mapping file id5431 NCBI file | EvidenceTAS |
| GenePOLR2C | AuthorityHGNC:9189 | Mapping file id5432 NCBI file | EvidenceTAS |
| GenePOLR2D | AuthorityHGNC:9191 | Mapping file id5433 NCBI file | EvidenceTAS |
| GenePOLR2E | AuthorityHGNC:9192 | Mapping file id5434 NCBI file | EvidenceTAS |
| GenePOLR2F | AuthorityHGNC:9193 | Mapping file id5435 NCBI file | EvidenceTAS |
| GenePOLR2G | AuthorityHGNC:9194 | Mapping file id5436 NCBI file | EvidenceTAS |
| GenePOLR2H | AuthorityHGNC:9195 | Mapping file id5437 NCBI file | EvidenceTAS |
| GenePOLR2I | AuthorityHGNC:9196 | Mapping file id5438 NCBI file | EvidenceTAS |
| GenePOLR2J | AuthorityHGNC:9197 | Mapping file id5439 NCBI file | EvidenceTAS |
| GenePOLR2K | AuthorityHGNC:9198 | Mapping file id5440 NCBI file | EvidenceTAS |
| GenePOLR2L | AuthorityHGNC:9199 | Mapping file id5441 NCBI file | EvidenceTAS |
| GenePPIE | AuthorityHGNC:9258 | Mapping file id10450 NCBI file | EvidenceTAS |
| GenePPIL1 | AuthorityHGNC:9260 | Mapping file id51645 NCBI file | EvidenceTAS |
| GenePPIL3 | AuthorityHGNC:9262 | Mapping file id53938 NCBI file | EvidenceTAS |
| GenePPIL4 | AuthorityHGNC:15702 | Mapping file id85313 NCBI file | EvidenceTAS |
| GenePPIL6 | AuthorityHGNC:21557 | Mapping file id285755 NCBI file | EvidenceTAS |
| GenePQBP1 | AuthorityHGNC:9330 | Mapping file id10084 NCBI file | EvidenceTAS |
| GenePRCC | AuthorityHGNC:9343 | Mapping file id5546 NCBI file | EvidenceTAS |
| GenePRKG1 | AuthorityHGNC:9414 | Mapping file id5592 NCBI file | EvidenceIEA |
| GenePRKG2 | AuthorityHGNC:9416 | Mapping file id5593 NCBI file | EvidenceIEA |
| GenePROS1 | AuthorityHGNC:9456 | Mapping file id5627 NCBI file | EvidenceTAS |
| GenePRPF19 | AuthorityHGNC:17896 | Mapping file id27339 NCBI file | EvidenceTAS |
| GenePRPF6 | AuthorityHGNC:15860 | Mapping file id24148 NCBI file | EvidenceTAS |
| GenePRPF8 | AuthorityHGNC:17340 | Mapping file id10594 NCBI file | EvidenceTAS |
| GenePRR5 | AuthorityHGNC:31682 | Mapping file id55615 NCBI file | EvidenceTAS |
| GenePTBP1 | AuthorityHGNC:9583 | Mapping file id5725 NCBI file | EvidenceTAS |
| GenePUF60 | AuthorityHGNC:17042 | Mapping file id22827 NCBI file | EvidenceTAS |
| GeneRBM10 | AuthorityHGNC:9896 | Mapping file id8241 NCBI file | EvidenceTAS |
| GeneRBM17 | AuthorityHGNC:16944 | Mapping file id84991 NCBI file | EvidenceTAS |
| GeneRBM22 | AuthorityHGNC:25503 | Mapping file id55696 NCBI file | EvidenceTAS |
| GeneRBM5 | AuthorityHGNC:9902 | Mapping file id10181 NCBI file | EvidenceTAS |
Evidence codes on this page: IEA, TAS, as the mapping file writes them; a row carrying two was written twice by the file, once under each. The mapping file id says which file placed the gene: an NCBI Gene id from NCBI2Reactome_All_Levels.txt, an Ensembl gene id from Ensembl2Reactome_All_Levels.txt. The two files can disagree about a code, so a row's codes are the one file's view. Measured by this site's build over this release on 2026-09-09: of the 138,908 human pathway-gene pairs both files place, 207 (0.149 per cent, over 47 genes) carry TAS in the Ensembl file where the NCBI rows carry IEA alone.
- Reactome mapping files, the human rows for this pathway · Reactome release 97 · read · Reactome downloads"NCBI2Reactome_All_Levels.txt" and "Ensembl2Reactome_All_Levels.txt", Reactome, release 97, https://reactome.org/download-data/ (date of access 2026-09-09). Data CC0; attribution encouraged.
03The hierarchy
Parents and children in this release's hierarchy
Reactome's hierarchy is a graph rather than a tree: a pathway can sit under more than one parent, and the gene counts are each pathway's own placements at every level under it, so a parent's count is not the sum of its children's.
- Reactome, the human pathway list and hierarchy relationship file · Reactome release 97 · read · Reactome downloads"ReactomePathways.txt" and "ReactomePathwaysRelation.txt", Reactome, release 97, https://reactome.org/download-data/ (date of access 2026-09-09). Data CC0; attribution encouraged.