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Pathway Human Homo sapiens

SLC-mediated transport of organic anions

R-HSA-9955298 in Reactome release 97: under SLC-mediated transmembrane transport, with 38 genes placed in it by the mapping files and 5 child pathways in the hierarchy.

The same number in the other species

Reactome writes the mouse and rat events it infers from a human pathway under the human number with the species token. A door opens only where that species' own list in this release holds the id: R-MMU-9955298 (mouse), R-RNO-9955298 (rat). Whether the event was inferred from this one is what the record says.

01The record

Reactome's own record of this pathway

What this tells you

The pathway list, the hierarchy and the genes on this page are read from the files Reactome publishes for Reactome release 97, built into this site on 2026-09-09: the pathway list, the hierarchy relationship file and the two gene mapping files. The record card is the one live read, Reactome's own record of this pathway.

Reactome's download page describes the mapping files: Mapping files link the source database identifier to the lowest level pathway diagram or subset of the pathway, all levels of the pathway hierarchy or database identifier to all reactions. [R13] The gene list here is the all-levels mapping of NCBI Gene ids, filled from the all-levels mapping of Ensembl ids where the NCBI file has no row for a gene; each row names which file it came from by the shape of its source id. Each row carries the evidence codes the file writes for it, as written and unranked, and both where the file writes both; no page of Reactome's documentation the survey read defines the codes, so this page does not expand them. A gene id the identity files do not name is kept as the source's own id with no door rather than turned into a symbol.

On citing what a search finds, Reactome says: It should be remembered that while we strive to contain the most current and accurate data, Reactome should not be used in citations where other primary sources of information are available. [R12] The record card prints the literature Reactome attaches to a curated pathway for that reason. The data are public domain: All data in the Reactome database and files derived from that data are licensed under the Creative Commons Public Domain Dedication (CC0). User may copy, modify, and distribute these data, even for commercial purposes, without asking for permission. Attribution is encouraged but not required. [R10] The pathway illustrations are licensed apart, under CC BY 4.0, and none is shown here.

A gene on this list is one Reactome places in this pathway in this release, and that is all the row says: it does not say the gene is expressed in a tissue or associated with a disease, which are the other two explorers' questions, read from other sources. Reactome's papers of record are [R01] [R02].

  1. [R01] Ragueneau E, Gong C, Sinquin P, Sevilla C, Beavers D, Grentner A, et al. (2026). The Reactome Knowledgebase 2026. Nucleic Acids Research 54:D673-D681. PMID 41251150, doi 10.1093/nar/gkaf1223.
  2. [R02] Milacic M, Beavers D, Conley P, Gong C, Gillespie M, Griss J, et al. (2024). The Reactome Pathway Knowledgebase 2024. Nucleic Acids Research 52:D672-D678. PMID 37941124, doi 10.1093/nar/gkad1025.
  3. [R10] Reactome, reactome.org. License Agreement. https://reactome.org/license, read 2026-09-09.
  4. [R12] Reactome, reactome.org. Citing us. https://reactome.org/cite, read 2026-09-09.
  5. [R13] Reactome, reactome.org. Download. https://reactome.org/download-data, read 2026-09-09.
Reading this pathway's record from Reactome (the pathway record).Still reading. A first read of a pathway can take a while; this page waits up to 35 seconds for it, and its scripts then bring in the panel, or a line saying what did not arrive.

02The genes

Genes Reactome places in this human pathway

The mapping files place 38 genes in this human pathway; showing 1 to 38, in pages of 100, sorted by symbol for reading. The order carries no ranking.

Genes Reactome places in this human pathway, page 1 of 1
GeneAVPAuthorityHGNC:894Mapping file id551 NCBI fileEvidenceTAS
GeneBSGAuthorityHGNC:1116Mapping file id682 NCBI fileEvidenceTAS
GeneEMBAuthorityHGNC:30465Mapping file id133418 NCBI fileEvidenceTAS
GeneSLC10A6AuthorityHGNC:30603Mapping file id345274 NCBI fileEvidenceTAS
GeneSLC13A2AuthorityHGNC:10917Mapping file id9058 NCBI fileEvidenceTAS
GeneSLC13A3AuthorityHGNC:14430Mapping file id64849 NCBI fileEvidenceTAS
GeneSLC13A5AuthorityHGNC:23089Mapping file id284111 NCBI fileEvidenceTAS
GeneSLC16A1AuthorityHGNC:10922Mapping file id6566 NCBI fileEvidenceTAS
GeneSLC16A2AuthorityHGNC:10923Mapping file id6567 NCBI fileEvidenceTAS
GeneSLC16A3AuthorityHGNC:10924Mapping file id9123 NCBI fileEvidenceTAS
GeneSLC16A7AuthorityHGNC:10928Mapping file id9194 NCBI fileEvidenceTAS
GeneSLC16A8AuthorityHGNC:16270Mapping file id23539 NCBI fileEvidenceTAS
GeneSLC17A5AuthorityHGNC:10933Mapping file id26503 NCBI fileEvidenceTAS
GeneSLC22A11AuthorityHGNC:18120Mapping file id55867 NCBI fileEvidenceTAS
GeneSLC22A12AuthorityHGNC:17989Mapping file id116085 NCBI fileEvidenceTAS
GeneSLC22A6AuthorityHGNC:10970Mapping file id9356 NCBI fileEvidenceTAS
GeneSLC22A7AuthorityHGNC:10971Mapping file id10864 NCBI fileEvidenceTAS
GeneSLC22A8AuthorityHGNC:10972Mapping file id9376 NCBI fileEvidenceTAS
GeneSLC25A1AuthorityHGNC:10979Mapping file id6576 NCBI fileEvidenceTAS
GeneSLC25A10AuthorityHGNC:10980Mapping file id1468 NCBI fileEvidenceTAS
GeneSLC25A11AuthorityHGNC:10981Mapping file id8402 NCBI fileEvidenceTAS
GeneSLC44A1AuthorityHGNC:18798Mapping file id23446 NCBI fileEvidenceTAS
GeneSLC44A2AuthorityHGNC:17292Mapping file id57153 NCBI fileEvidenceTAS
GeneSLC44A3AuthorityHGNC:28689Mapping file id126969 NCBI fileEvidenceTAS
GeneSLC44A4AuthorityHGNC:13941Mapping file id80736 NCBI fileEvidenceTAS
GeneSLC44A5AuthorityHGNC:28524Mapping file id204962 NCBI fileEvidenceTAS
GeneSLC5A12AuthorityHGNC:28750Mapping file id159963 NCBI fileEvidenceTAS
GeneSLC5A7AuthorityHGNC:14025Mapping file id60482 NCBI fileEvidenceTAS
GeneSLC5A8AuthorityHGNC:19119Mapping file id160728 NCBI fileEvidenceTAS
GeneSLCO1A2AuthorityHGNC:10956Mapping file id6579 NCBI fileEvidenceTAS
GeneSLCO1B1AuthorityHGNC:10959Mapping file id10599 NCBI fileEvidenceTAS
GeneSLCO1B3AuthorityHGNC:10961Mapping file id28234 NCBI fileEvidenceTAS
GeneSLCO1C1AuthorityHGNC:13819Mapping file id53919 NCBI fileEvidenceTAS
GeneSLCO2A1AuthorityHGNC:10955Mapping file id6578 NCBI fileEvidenceTAS
GeneSLCO2B1AuthorityHGNC:10962Mapping file id11309 NCBI fileEvidenceTAS
GeneSLCO3A1AuthorityHGNC:10952Mapping file id28232 NCBI fileEvidenceTAS
GeneSLCO4A1AuthorityHGNC:10953Mapping file id28231 NCBI fileEvidenceTAS
GeneSLCO4C1AuthorityHGNC:23612Mapping file id353189 NCBI fileEvidenceTAS

Evidence codes on this page: TAS, as the mapping file writes them; a row carrying two was written twice by the file, once under each. The mapping file id says which file placed the gene: an NCBI Gene id from NCBI2Reactome_All_Levels.txt, an Ensembl gene id from Ensembl2Reactome_All_Levels.txt. The two files can disagree about a code, so a row's codes are the one file's view. Measured by this site's build over this release on 2026-09-09: of the 138,908 human pathway-gene pairs both files place, 207 (0.149 per cent, over 47 genes) carry TAS in the Ensembl file where the NCBI rows carry IEA alone.

  • Reactome mapping files, the human rows for this pathway · Reactome release 97 · read · Reactome downloads"NCBI2Reactome_All_Levels.txt" and "Ensembl2Reactome_All_Levels.txt", Reactome, release 97, https://reactome.org/download-data/ (date of access 2026-09-09). Data CC0; attribution encouraged.

03The hierarchy

Parents and children in this release's hierarchy

Reactome's hierarchy is a graph rather than a tree: a pathway can sit under more than one parent, and the gene counts are each pathway's own placements at every level under it, so a parent's count is not the sum of its children's.

  • Reactome, the human pathway list and hierarchy relationship file · Reactome release 97 · read · Reactome downloads"ReactomePathways.txt" and "ReactomePathwaysRelation.txt", Reactome, release 97, https://reactome.org/download-data/ (date of access 2026-09-09). Data CC0; attribution encouraged.