Pathway Human Homo sapiens
Transport of small molecules
R-HSA-382551 in Reactome release 97: a top-level pathway, with 722 genes placed in it by the mapping files and 11 child pathways in the hierarchy.
The same number in the other species
Reactome writes the mouse and rat events it infers from a human pathway under the human number with the species token. A door opens only where that species' own list in this release holds the id: R-MMU-382551 (mouse), R-RNO-382551 (rat). Whether the event was inferred from this one is what the record says.
01The record
Reactome's own record of this pathway
What this tells you
The pathway list, the hierarchy and the genes on this page are read from the files Reactome publishes for Reactome release 97, built into this site on 2026-09-09: the pathway list, the hierarchy relationship file and the two gene mapping files. The record card is the one live read, Reactome's own record of this pathway.
Reactome's download page describes the mapping files: Mapping files link the source database identifier to the lowest level pathway diagram or subset of the pathway, all levels of the pathway hierarchy or database identifier to all reactions.
[R13] The gene list here is the all-levels mapping of NCBI Gene ids, filled from the all-levels mapping of Ensembl ids where the NCBI file has no row for a gene; each row names which file it came from by the shape of its source id. Each row carries the evidence codes the file writes for it, as written and unranked, and both where the file writes both; no page of Reactome's documentation the survey read defines the codes, so this page does not expand them. A gene id the identity files do not name is kept as the source's own id with no door rather than turned into a symbol.
On citing what a search finds, Reactome says: It should be remembered that while we strive to contain the most current and accurate data, Reactome should not be used in citations where other primary sources of information are available.
[R12] The record card prints the literature Reactome attaches to a curated pathway for that reason. The data are public domain: All data in the Reactome database and files derived from that data are licensed under the Creative Commons Public Domain Dedication (CC0). User may copy, modify, and distribute these data, even for commercial purposes, without asking for permission. Attribution is encouraged but not required.
[R10] The pathway illustrations are licensed apart, under CC BY 4.0, and none is shown here.
A gene on this list is one Reactome places in this pathway in this release, and that is all the row says: it does not say the gene is expressed in a tissue or associated with a disease, which are the other two explorers' questions, read from other sources. Reactome's papers of record are [R01] [R02].
- [R01] Ragueneau E, Gong C, Sinquin P, Sevilla C, Beavers D, Grentner A, et al. (2026). The Reactome Knowledgebase 2026. Nucleic Acids Research 54:D673-D681. PMID 41251150, doi 10.1093/nar/gkaf1223.
- [R02] Milacic M, Beavers D, Conley P, Gong C, Gillespie M, Griss J, et al. (2024). The Reactome Pathway Knowledgebase 2024. Nucleic Acids Research 52:D672-D678. PMID 37941124, doi 10.1093/nar/gkad1025.
- [R10] Reactome, reactome.org. License Agreement. https://reactome.org/license, read 2026-09-09.
- [R12] Reactome, reactome.org. Citing us. https://reactome.org/cite, read 2026-09-09.
- [R13] Reactome, reactome.org. Download. https://reactome.org/download-data, read 2026-09-09.
02The genes
Genes Reactome places in this human pathway
The mapping files place 722 genes in this human pathway; showing 101 to 200, in pages of 100, sorted by symbol for reading. The order carries no ranking.
| Gene | Authority id | Mapping file id | Evidence codes |
|---|---|---|---|
| GeneAQP9 | AuthorityHGNC:643 | Mapping file id366 NCBI file | EvidenceTAS |
| GeneARF1 | AuthorityHGNC:652 | Mapping file id375 NCBI file | EvidenceTAS |
| GeneARL2 | AuthorityHGNC:693 | Mapping file id402 NCBI file | EvidenceTAS |
| GeneARL2BP | AuthorityHGNC:17146 | Mapping file id23568 NCBI file | EvidenceTAS |
| GeneASIC1 | AuthorityHGNC:100 | Mapping file id41 NCBI file | EvidenceTAS |
| GeneASIC2 | AuthorityHGNC:99 | Mapping file id40 NCBI file | EvidenceTAS |
| GeneASIC3 | AuthorityHGNC:101 | Mapping file id9311 NCBI file | EvidenceTAS |
| GeneASIC4 | AuthorityHGNC:21263 | Mapping file id55515 NCBI file | EvidenceTAS |
| GeneASIC5 | AuthorityHGNC:17537 | Mapping file id51802 NCBI file | EvidenceTAS |
| GeneASPH | AuthorityHGNC:757 | Mapping file id444 NCBI file | EvidenceTAS |
| GeneATP10A | AuthorityHGNC:13542 | Mapping file id57194 NCBI file | EvidenceTAS |
| GeneATP10B | AuthorityHGNC:13543 | Mapping file id23120 NCBI file | EvidenceTAS |
| GeneATP10D | AuthorityHGNC:13549 | Mapping file id57205 NCBI file | EvidenceTAS |
| GeneATP11A | AuthorityHGNC:13552 | Mapping file id23250 NCBI file | EvidenceTAS |
| GeneATP11B | AuthorityHGNC:13553 | Mapping file id23200 NCBI file | EvidenceTAS |
| GeneATP11C | AuthorityHGNC:13554 | Mapping file id286410 NCBI file | EvidenceTAS |
| GeneATP12A | AuthorityHGNC:13816 | Mapping file id479 NCBI file | EvidenceTAS |
| GeneATP13A1 | AuthorityHGNC:24215 | Mapping file id57130 NCBI file | EvidenceTAS |
| GeneATP13A2 | AuthorityHGNC:30213 | Mapping file id23400 NCBI file | EvidenceTAS |
| GeneATP13A4 | AuthorityHGNC:25422 | Mapping file id84239 NCBI file | EvidenceTAS |
| GeneATP13A5 | AuthorityHGNC:31789 | Mapping file id344905 NCBI file | EvidenceTAS |
| GeneATP1A1 | AuthorityHGNC:799 | Mapping file id476 NCBI file | EvidenceTAS |
| GeneATP1A2 | AuthorityHGNC:800 | Mapping file id477 NCBI file | EvidenceTAS |
| GeneATP1A3 | AuthorityHGNC:801 | Mapping file id478 NCBI file | EvidenceTAS |
| GeneATP1A4 | AuthorityHGNC:14073 | Mapping file id480 NCBI file | EvidenceTAS |
| GeneATP1B1 | AuthorityHGNC:804 | Mapping file id481 NCBI file | EvidenceTAS |
| GeneATP1B2 | AuthorityHGNC:805 | Mapping file id482 NCBI file | EvidenceTAS |
| GeneATP1B3 | AuthorityHGNC:806 | Mapping file id483 NCBI file | EvidenceTAS |
| GeneATP2A1 | AuthorityHGNC:811 | Mapping file id487 NCBI file | EvidenceTAS |
| GeneATP2A2 | AuthorityHGNC:812 | Mapping file id488 NCBI file | EvidenceTAS |
| GeneATP2A3 | AuthorityHGNC:813 | Mapping file id489 NCBI file | EvidenceTAS |
| GeneATP2B1 | AuthorityHGNC:814 | Mapping file id490 NCBI file | EvidenceTAS |
| GeneATP2B2 | AuthorityHGNC:815 | Mapping file id491 NCBI file | EvidenceTAS |
| GeneATP2B3 | AuthorityHGNC:816 | Mapping file id492 NCBI file | EvidenceTAS |
| GeneATP2B4 | AuthorityHGNC:817 | Mapping file id493 NCBI file | EvidenceTAS |
| GeneATP2C1 | AuthorityHGNC:13211 | Mapping file id27032 NCBI file | EvidenceTAS |
| GeneATP2C2 | AuthorityHGNC:29103 | Mapping file id9914 NCBI file | EvidenceTAS |
| GeneATP4A | AuthorityHGNC:819 | Mapping file id495 NCBI file | EvidenceTAS |
| GeneATP4B | AuthorityHGNC:820 | Mapping file id496 NCBI file | EvidenceTAS |
| GeneATP6AP1 | AuthorityHGNC:868 | Mapping file id537 NCBI file | EvidenceTAS |
| GeneATP6V0A1 | AuthorityHGNC:865 | Mapping file id535 NCBI file | EvidenceTAS |
| GeneATP6V0A2 | AuthorityHGNC:18481 | Mapping file id23545 NCBI file | EvidenceTAS |
| GeneATP6V0A4 | AuthorityHGNC:866 | Mapping file id50617 NCBI file | EvidenceTAS |
| GeneATP6V0B | AuthorityHGNC:861 | Mapping file id533 NCBI file | EvidenceTAS |
| GeneATP6V0C | AuthorityHGNC:855 | Mapping file id527 NCBI file | EvidenceTAS |
| GeneATP6V0D1 | AuthorityHGNC:13724 | Mapping file id9114 NCBI file | EvidenceTAS |
| GeneATP6V0D2 | AuthorityHGNC:18266 | Mapping file id245972 NCBI file | EvidenceTAS |
| GeneATP6V0E1 | AuthorityHGNC:863 | Mapping file id8992 NCBI file | EvidenceTAS |
| GeneATP6V0E2 | AuthorityHGNC:21723 | Mapping file id155066 NCBI file | EvidenceTAS |
| GeneATP6V1A | AuthorityHGNC:851 | Mapping file id523 NCBI file | EvidenceTAS |
| GeneATP6V1B1 | AuthorityHGNC:853 | Mapping file id525 NCBI file | EvidenceTAS |
| GeneATP6V1B2 | AuthorityHGNC:854 | Mapping file id526 NCBI file | EvidenceTAS |
| GeneATP6V1C1 | AuthorityHGNC:856 | Mapping file id528 NCBI file | EvidenceTAS |
| GeneATP6V1C2 | AuthorityHGNC:18264 | Mapping file id245973 NCBI file | EvidenceTAS |
| GeneATP6V1D | AuthorityHGNC:13527 | Mapping file id51382 NCBI file | EvidenceTAS |
| GeneATP6V1E1 | AuthorityHGNC:857 | Mapping file id529 NCBI file | EvidenceTAS |
| GeneATP6V1E2 | AuthorityHGNC:18125 | Mapping file id90423 NCBI file | EvidenceTAS |
| GeneATP6V1F | AuthorityHGNC:16832 | Mapping file id9296 NCBI file | EvidenceTAS |
| GeneATP6V1G1 | AuthorityHGNC:864 | Mapping file id9550 NCBI file | EvidenceTAS |
| GeneATP6V1G2 | AuthorityHGNC:862 | Mapping file id534 NCBI file | EvidenceTAS |
| GeneATP6V1G3 | AuthorityHGNC:18265 | Mapping file id127124 NCBI file | EvidenceTAS |
| GeneATP6V1H | AuthorityHGNC:18303 | Mapping file id51606 NCBI file | EvidenceTAS |
| GeneATP7A | AuthorityHGNC:869 | Mapping file id538 NCBI file | EvidenceTAS |
| GeneATP7B | AuthorityHGNC:870 | Mapping file id540 NCBI file | EvidenceTAS |
| GeneATP8A1 | AuthorityHGNC:13531 | Mapping file id10396 NCBI file | EvidenceTAS |
| GeneATP8A2 | AuthorityHGNC:13533 | Mapping file id51761 NCBI file | EvidenceTAS |
| GeneATP8B1 | AuthorityHGNC:3706 | Mapping file id5205 NCBI file | EvidenceTAS |
| GeneATP8B2 | AuthorityHGNC:13534 | Mapping file id57198 NCBI file | EvidenceTAS |
| GeneATP8B3 | AuthorityHGNC:13535 | Mapping file id148229 NCBI file | EvidenceTAS |
| GeneATP8B4 | AuthorityHGNC:13536 | Mapping file id79895 NCBI file | EvidenceTAS |
| GeneATP9A | AuthorityHGNC:13540 | Mapping file id10079 NCBI file | EvidenceTAS |
| GeneATP9B | AuthorityHGNC:13541 | Mapping file id374868 NCBI file | EvidenceTAS |
| GeneAVP | AuthorityHGNC:894 | Mapping file id551 NCBI file | EvidenceTAS |
| GeneAVPR2 | AuthorityHGNC:897 | Mapping file id554 NCBI file | EvidenceTAS |
| GeneAZGP1 | AuthorityHGNC:910 | Mapping file id563 NCBI file | EvidenceTAS |
| GeneBEST1 | AuthorityHGNC:12703 | Mapping file id7439 NCBI file | EvidenceTAS |
| GeneBEST2 | AuthorityHGNC:17107 | Mapping file id54831 NCBI file | EvidenceTAS |
| GeneBEST3 | AuthorityHGNC:17105 | Mapping file id144453 NCBI file | EvidenceTAS |
| GeneBEST4 | AuthorityHGNC:17106 | Mapping file id266675 NCBI file | EvidenceTAS |
| GeneBMP1 | AuthorityHGNC:1067 | Mapping file id649 NCBI file | EvidenceTAS |
| GeneBSG | AuthorityHGNC:1116 | Mapping file id682 NCBI file | EvidenceTAS |
| GeneBSND | AuthorityHGNC:16512 | Mapping file id7809 NCBI file | EvidenceTAS |
| GeneCA1 | AuthorityHGNC:1368 | Mapping file id759 NCBI file | EvidenceTAS |
| GeneCA2 | AuthorityHGNC:1373 | Mapping file id760 NCBI file | EvidenceTAS |
| GeneCA4 | AuthorityHGNC:1375 | Mapping file id762 NCBI file | EvidenceTAS |
| GeneCALM1 | AuthorityHGNC:1442 | Mapping file id801 NCBI file | EvidenceTAS |
| GeneCALM2 | AuthorityHGNC:1445 | Mapping file id805 NCBI file | EvidenceTAS |
| GeneCALM3 | AuthorityHGNC:1449 | Mapping file id808 NCBI file | EvidenceTAS |
| GeneCAMK2A | AuthorityHGNC:1460 | Mapping file id815 NCBI file | EvidenceTAS |
| GeneCAMK2B | AuthorityHGNC:1461 | Mapping file id816 NCBI file | EvidenceTAS |
| GeneCAMK2D | AuthorityHGNC:1462 | Mapping file id817 NCBI file | EvidenceTAS |
| GeneCAMK2G | AuthorityHGNC:1463 | Mapping file id818 NCBI file | EvidenceTAS |
| GeneCAND1 | AuthorityHGNC:30688 | Mapping file id55832 NCBI file | EvidenceTAS |
| GeneCASQ1 | AuthorityHGNC:1512 | Mapping file id844 NCBI file | EvidenceTAS |
| GeneCASQ2 | AuthorityHGNC:1513 | Mapping file id845 NCBI file | EvidenceTAS |
| GeneCES3 | AuthorityHGNC:1865 | Mapping file id23491 NCBI file | EvidenceTAS |
| GeneCETP | AuthorityHGNC:1869 | Mapping file id1071 NCBI file | EvidenceTAS |
| GeneCFTR | AuthorityHGNC:1884 | Mapping file id1080 NCBI file | EvidenceTAS |
| GeneCIDEC | AuthorityHGNC:24229 | Mapping file id63924 NCBI file | EvidenceIEA |
| GeneCLCA1 | AuthorityHGNC:2015 | Mapping file id1179 NCBI file | EvidenceTAS |
Evidence codes on this page: IEA, TAS, as the mapping file writes them; a row carrying two was written twice by the file, once under each. The mapping file id says which file placed the gene: an NCBI Gene id from NCBI2Reactome_All_Levels.txt, an Ensembl gene id from Ensembl2Reactome_All_Levels.txt. The two files can disagree about a code, so a row's codes are the one file's view. Measured by this site's build over this release on 2026-09-09: of the 138,908 human pathway-gene pairs both files place, 207 (0.149 per cent, over 47 genes) carry TAS in the Ensembl file where the NCBI rows carry IEA alone.
- Reactome mapping files, the human rows for this pathway · Reactome release 97 · read · Reactome downloads"NCBI2Reactome_All_Levels.txt" and "Ensembl2Reactome_All_Levels.txt", Reactome, release 97, https://reactome.org/download-data/ (date of access 2026-09-09). Data CC0; attribution encouraged.
03The hierarchy
Parents and children in this release's hierarchy
Parents
None: this is a top-level pathway of the release.
Children
- ABC-family protein mediated transportR-HSA-38255690 genes
- Aquaporin-mediated transportR-HSA-44571752 genes
- Glycosphingolipid transportR-HSA-98455768 genes
- Intracellular oxygen transportR-HSA-89816073 genes
- Ion channel transportR-HSA-983712185 genes
- Iron uptake and transportR-HSA-91793758 genes
- Miscellaneous transport and binding eventsR-HSA-522334529 genes
- Mitochondrial calcium ion transportR-HSA-894921523 genes
- O2/CO2 exchange in erythrocytesR-HSA-148092613 genes
- Plasma lipoprotein assembly, remodeling, and clearanceR-HSA-17482475 genes
- SLC-mediated transmembrane transportR-HSA-425407245 genes
Reactome's hierarchy is a graph rather than a tree: a pathway can sit under more than one parent, and the gene counts are each pathway's own placements at every level under it, so a parent's count is not the sum of its children's.
- Reactome, the human pathway list and hierarchy relationship file · Reactome release 97 · read · Reactome downloads"ReactomePathways.txt" and "ReactomePathwaysRelation.txt", Reactome, release 97, https://reactome.org/download-data/ (date of access 2026-09-09). Data CC0; attribution encouraged.