Pathway Human Homo sapiens
Transport of small molecules
R-HSA-382551 in Reactome release 97: a top-level pathway, with 722 genes placed in it by the mapping files and 11 child pathways in the hierarchy.
The same number in the other species
Reactome writes the mouse and rat events it infers from a human pathway under the human number with the species token. A door opens only where that species' own list in this release holds the id: R-MMU-382551 (mouse), R-RNO-382551 (rat). Whether the event was inferred from this one is what the record says.
01The record
Reactome's own record of this pathway
What this tells you
The pathway list, the hierarchy and the genes on this page are read from the files Reactome publishes for Reactome release 97, built into this site on 2026-09-09: the pathway list, the hierarchy relationship file and the two gene mapping files. The record card is the one live read, Reactome's own record of this pathway.
Reactome's download page describes the mapping files: Mapping files link the source database identifier to the lowest level pathway diagram or subset of the pathway, all levels of the pathway hierarchy or database identifier to all reactions.
[R13] The gene list here is the all-levels mapping of NCBI Gene ids, filled from the all-levels mapping of Ensembl ids where the NCBI file has no row for a gene; each row names which file it came from by the shape of its source id. Each row carries the evidence codes the file writes for it, as written and unranked, and both where the file writes both; no page of Reactome's documentation the survey read defines the codes, so this page does not expand them. A gene id the identity files do not name is kept as the source's own id with no door rather than turned into a symbol.
On citing what a search finds, Reactome says: It should be remembered that while we strive to contain the most current and accurate data, Reactome should not be used in citations where other primary sources of information are available.
[R12] The record card prints the literature Reactome attaches to a curated pathway for that reason. The data are public domain: All data in the Reactome database and files derived from that data are licensed under the Creative Commons Public Domain Dedication (CC0). User may copy, modify, and distribute these data, even for commercial purposes, without asking for permission. Attribution is encouraged but not required.
[R10] The pathway illustrations are licensed apart, under CC BY 4.0, and none is shown here.
A gene on this list is one Reactome places in this pathway in this release, and that is all the row says: it does not say the gene is expressed in a tissue or associated with a disease, which are the other two explorers' questions, read from other sources. Reactome's papers of record are [R01] [R02].
- [R01] Ragueneau E, Gong C, Sinquin P, Sevilla C, Beavers D, Grentner A, et al. (2026). The Reactome Knowledgebase 2026. Nucleic Acids Research 54:D673-D681. PMID 41251150, doi 10.1093/nar/gkaf1223.
- [R02] Milacic M, Beavers D, Conley P, Gong C, Gillespie M, Griss J, et al. (2024). The Reactome Pathway Knowledgebase 2024. Nucleic Acids Research 52:D672-D678. PMID 37941124, doi 10.1093/nar/gkad1025.
- [R10] Reactome, reactome.org. License Agreement. https://reactome.org/license, read 2026-09-09.
- [R12] Reactome, reactome.org. Citing us. https://reactome.org/cite, read 2026-09-09.
- [R13] Reactome, reactome.org. Download. https://reactome.org/download-data, read 2026-09-09.
02The genes
Genes Reactome places in this human pathway
The mapping files place 722 genes in this human pathway; showing 401 to 500, in pages of 100, sorted by symbol for reading. The order carries no ranking.
| Gene | Authority id | Mapping file id | Evidence codes |
|---|---|---|---|
| GenePSMD8 | AuthorityHGNC:9566 | Mapping file id5714 NCBI file | EvidenceTAS |
| GeneRAB11A | AuthorityHGNC:9760 | Mapping file id8766 NCBI file | EvidenceTAS |
| GeneRAB11FIP2 | AuthorityHGNC:29152 | Mapping file id22841 NCBI file | EvidenceTAS |
| GeneRAF1 | AuthorityHGNC:9829 | Mapping file id5894 NCBI file | EvidenceTAS |
| GeneRHAG | AuthorityHGNC:10006 | Mapping file id6005 NCBI file | EvidenceTAS |
| GeneRHBG | AuthorityHGNC:14572 | Mapping file id57127 NCBI file | EvidenceTAS |
| GeneRHCG | AuthorityHGNC:18140 | Mapping file id51458 NCBI file | EvidenceTAS |
| GeneRIPK1 | AuthorityHGNC:10019 | Mapping file id8737 NCBI file | EvidenceTAS |
| GeneRIPK3 | AuthorityHGNC:10021 | Mapping file id11035 NCBI file | EvidenceTAS |
| GeneRNF185 | AuthorityHGNC:26783 | Mapping file id91445 NCBI file | EvidenceTAS |
| GeneRNF5 | AuthorityHGNC:10068 | Mapping file id6048 NCBI file | EvidenceTAS |
| GeneRPS27A | AuthorityHGNC:10417 | Mapping file id6233 NCBI file | EvidenceTAS |
| GeneRUNX1 | AuthorityHGNC:10471 | Mapping file id861 NCBI file | EvidenceTAS |
| GeneRYR1 | AuthorityHGNC:10483 | Mapping file id6261 NCBI file | EvidenceTAS |
| GeneRYR2 | AuthorityHGNC:10484 | Mapping file id6262 NCBI file | EvidenceTAS |
| GeneRYR3 | AuthorityHGNC:10485 | Mapping file id6263 NCBI file | EvidenceTAS |
| GeneSAR1B | AuthorityHGNC:10535 | Mapping file id51128 NCBI file | EvidenceTAS |
| GeneSCARB1 | AuthorityHGNC:1664 | Mapping file id949 NCBI file | EvidenceTAS |
| GeneSCNN1A | AuthorityHGNC:10599 | Mapping file id6337 NCBI file | EvidenceTAS |
| GeneSCNN1B | AuthorityHGNC:10600 | Mapping file id6338 NCBI file | EvidenceTAS |
| GeneSCNN1D | AuthorityHGNC:10601 | Mapping file id6339 NCBI file | EvidenceTAS |
| GeneSCNN1G | AuthorityHGNC:10602 | Mapping file id6340 NCBI file | EvidenceTAS |
| GeneSEL1L | AuthorityHGNC:10717 | Mapping file id6400 NCBI file | EvidenceTAS |
| GeneSEM1 | AuthorityHGNC:10845 | Mapping file id7979 NCBI file | EvidenceTAS |
| GeneSGK1 | AuthorityHGNC:10810 | Mapping file id6446 NCBI file | EvidenceTAS |
| GeneSGK2 | AuthorityHGNC:13900 | Mapping file id10110 NCBI file | EvidenceTAS |
| GeneSGK3 | AuthorityHGNC:10812 | Mapping file id23678 NCBI file | EvidenceTAS |
| GeneSKP1 | AuthorityHGNC:10899 | Mapping file id6500 NCBI file | EvidenceTAS |
| GeneSLC10A6 | AuthorityHGNC:30603 | Mapping file id345274 NCBI file | EvidenceTAS |
| GeneSLC11A1 | AuthorityHGNC:10907 | Mapping file id6556 NCBI file | EvidenceTAS |
| GeneSLC11A2 | AuthorityHGNC:10908 | Mapping file id4891 NCBI file | EvidenceTAS |
| GeneSLC12A1 | AuthorityHGNC:10910 | Mapping file id6557 NCBI file | EvidenceTAS |
| GeneSLC12A2 | AuthorityHGNC:10911 | Mapping file id6558 NCBI file | EvidenceTAS |
| GeneSLC12A3 | AuthorityHGNC:10912 | Mapping file id6559 NCBI file | EvidenceTAS |
| GeneSLC12A4 | AuthorityHGNC:10913 | Mapping file id6560 NCBI file | EvidenceTAS |
| GeneSLC12A5 | AuthorityHGNC:13818 | Mapping file id57468 NCBI file | EvidenceTAS |
| GeneSLC12A6 | AuthorityHGNC:10914 | Mapping file id9990 NCBI file | EvidenceTAS |
| GeneSLC12A7 | AuthorityHGNC:10915 | Mapping file id10723 NCBI file | EvidenceTAS |
| GeneSLC13A1 | AuthorityHGNC:10916 | Mapping file id6561 NCBI file | EvidenceTAS |
| GeneSLC13A2 | AuthorityHGNC:10917 | Mapping file id9058 NCBI file | EvidenceTAS |
| GeneSLC13A3 | AuthorityHGNC:14430 | Mapping file id64849 NCBI file | EvidenceTAS |
| GeneSLC13A4 | AuthorityHGNC:15827 | Mapping file id26266 NCBI file | EvidenceTAS |
| GeneSLC13A5 | AuthorityHGNC:23089 | Mapping file id284111 NCBI file | EvidenceTAS |
| GeneSLC14A1 | AuthorityHGNC:10918 | Mapping file id6563 NCBI file | EvidenceTAS |
| GeneSLC14A2 | AuthorityHGNC:10919 | Mapping file id8170 NCBI file | EvidenceTAS |
| GeneSLC15A1 | AuthorityHGNC:10920 | Mapping file id6564 NCBI file | EvidenceTAS |
| GeneSLC15A3 | AuthorityHGNC:18068 | Mapping file id51296 NCBI file | EvidenceTAS |
| GeneSLC15A4 | AuthorityHGNC:23090 | Mapping file id121260 NCBI file | EvidenceTAS |
| GeneSLC16A1 | AuthorityHGNC:10922 | Mapping file id6566 NCBI file | EvidenceTAS |
| GeneSLC16A10 | AuthorityHGNC:17027 | Mapping file id117247 NCBI file | EvidenceTAS |
| GeneSLC16A2 | AuthorityHGNC:10923 | Mapping file id6567 NCBI file | EvidenceTAS |
| GeneSLC16A3 | AuthorityHGNC:10924 | Mapping file id9123 NCBI file | EvidenceTAS |
| GeneSLC16A7 | AuthorityHGNC:10928 | Mapping file id9194 NCBI file | EvidenceTAS |
| GeneSLC16A8 | AuthorityHGNC:16270 | Mapping file id23539 NCBI file | EvidenceTAS |
| GeneSLC17A1 | AuthorityHGNC:10929 | Mapping file id6568 NCBI file | EvidenceTAS |
| GeneSLC17A3 | AuthorityHGNC:10931 | Mapping file id10786 NCBI file | EvidenceTAS |
| GeneSLC17A5 | AuthorityHGNC:10933 | Mapping file id26503 NCBI file | EvidenceTAS |
| GeneSLC17A6 | AuthorityHGNC:16703 | Mapping file id57084 NCBI file | EvidenceTAS |
| GeneSLC17A7 | AuthorityHGNC:16704 | Mapping file id57030 NCBI file | EvidenceTAS |
| GeneSLC17A8 | AuthorityHGNC:20151 | Mapping file id246213 NCBI file | EvidenceTAS |
| GeneSLC1A1 | AuthorityHGNC:10939 | Mapping file id6505 NCBI file | EvidenceTAS |
| GeneSLC1A2 | AuthorityHGNC:10940 | Mapping file id6506 NCBI file | EvidenceTAS |
| GeneSLC1A3 | AuthorityHGNC:10941 | Mapping file id6507 NCBI file | EvidenceTAS |
| GeneSLC1A4 | AuthorityHGNC:10942 | Mapping file id6509 NCBI file | EvidenceTAS |
| GeneSLC1A5 | AuthorityHGNC:10943 | Mapping file id6510 NCBI file | EvidenceTAS |
| GeneSLC1A6 | AuthorityHGNC:10944 | Mapping file id6511 NCBI file | EvidenceTAS |
| GeneSLC1A7 | AuthorityHGNC:10945 | Mapping file id6512 NCBI file | EvidenceTAS |
| GeneSLC20A1 | AuthorityHGNC:10946 | Mapping file id6574 NCBI file | EvidenceTAS |
| GeneSLC20A2 | AuthorityHGNC:10947 | Mapping file id6575 NCBI file | EvidenceTAS |
| GeneSLC22A1 | AuthorityHGNC:10963 | Mapping file id6580 NCBI file | EvidenceTAS |
| GeneSLC22A11 | AuthorityHGNC:18120 | Mapping file id55867 NCBI file | EvidenceTAS |
| GeneSLC22A12 | AuthorityHGNC:17989 | Mapping file id116085 NCBI file | EvidenceTAS |
| GeneSLC22A15 | AuthorityHGNC:20301 | Mapping file id55356 NCBI file | EvidenceTAS |
| GeneSLC22A16 | AuthorityHGNC:20302 | Mapping file id85413 NCBI file | EvidenceTAS |
| GeneSLC22A17 | AuthorityHGNC:23095 | Mapping file id51310 NCBI file | EvidenceIEA, TAS |
| GeneSLC22A2 | AuthorityHGNC:10966 | Mapping file id6582 NCBI file | EvidenceTAS |
| GeneSLC22A3 | AuthorityHGNC:10967 | Mapping file id6581 NCBI file | EvidenceTAS |
| GeneSLC22A4 | AuthorityHGNC:10968 | Mapping file id6583 NCBI file | EvidenceTAS |
| GeneSLC22A5 | AuthorityHGNC:10969 | Mapping file id6584 NCBI file | EvidenceTAS |
| GeneSLC22A6 | AuthorityHGNC:10970 | Mapping file id9356 NCBI file | EvidenceTAS |
| GeneSLC22A7 | AuthorityHGNC:10971 | Mapping file id10864 NCBI file | EvidenceTAS |
| GeneSLC22A8 | AuthorityHGNC:10972 | Mapping file id9376 NCBI file | EvidenceTAS |
| GeneSLC24A1 | AuthorityHGNC:10975 | Mapping file id9187 NCBI file | EvidenceTAS |
| GeneSLC24A2 | AuthorityHGNC:10976 | Mapping file id25769 NCBI file | EvidenceTAS |
| GeneSLC24A3 | AuthorityHGNC:10977 | Mapping file id57419 NCBI file | EvidenceTAS |
| GeneSLC24A4 | AuthorityHGNC:10978 | Mapping file id123041 NCBI file | EvidenceTAS |
| GeneSLC24A5 | AuthorityHGNC:20611 | Mapping file id283652 NCBI file | EvidenceTAS |
| GeneSLC25A1 | AuthorityHGNC:10979 | Mapping file id6576 NCBI file | EvidenceTAS |
| GeneSLC25A10 | AuthorityHGNC:10980 | Mapping file id1468 NCBI file | EvidenceTAS |
| GeneSLC25A11 | AuthorityHGNC:10981 | Mapping file id8402 NCBI file | EvidenceTAS |
| GeneSLC25A18 | AuthorityHGNC:10988 | Mapping file id83733 NCBI file | EvidenceTAS |
| GeneSLC25A22 | AuthorityHGNC:19954 | Mapping file id79751 NCBI file | EvidenceTAS |
| GeneSLC25A26 | AuthorityHGNC:20661 | Mapping file id115286 NCBI file | EvidenceTAS |
| GeneSLC25A29 | AuthorityHGNC:20116 | Mapping file id123096 NCBI file | EvidenceTAS |
| GeneSLC25A4 | AuthorityHGNC:10990 | Mapping file id291 NCBI file | EvidenceTAS |
| GeneSLC25A5 | AuthorityHGNC:10991 | Mapping file id292 NCBI file | EvidenceTAS |
| GeneSLC25A6 | AuthorityHGNC:10992 | Mapping file id293 NCBI file | EvidenceTAS |
| GeneSLC26A1 | AuthorityHGNC:10993 | Mapping file id10861 NCBI file | EvidenceTAS |
| GeneSLC26A11 | AuthorityHGNC:14471 | Mapping file id284129 NCBI file | EvidenceTAS |
| GeneSLC26A2 | AuthorityHGNC:10994 | Mapping file id1836 NCBI file | EvidenceTAS |
Evidence codes on this page: IEA, TAS, as the mapping file writes them; a row carrying two was written twice by the file, once under each. The mapping file id says which file placed the gene: an NCBI Gene id from NCBI2Reactome_All_Levels.txt, an Ensembl gene id from Ensembl2Reactome_All_Levels.txt. The two files can disagree about a code, so a row's codes are the one file's view. Measured by this site's build over this release on 2026-09-09: of the 138,908 human pathway-gene pairs both files place, 207 (0.149 per cent, over 47 genes) carry TAS in the Ensembl file where the NCBI rows carry IEA alone.
- Reactome mapping files, the human rows for this pathway · Reactome release 97 · read · Reactome downloads"NCBI2Reactome_All_Levels.txt" and "Ensembl2Reactome_All_Levels.txt", Reactome, release 97, https://reactome.org/download-data/ (date of access 2026-09-09). Data CC0; attribution encouraged.
03The hierarchy
Parents and children in this release's hierarchy
Parents
None: this is a top-level pathway of the release.
Children
- ABC-family protein mediated transportR-HSA-38255690 genes
- Aquaporin-mediated transportR-HSA-44571752 genes
- Glycosphingolipid transportR-HSA-98455768 genes
- Intracellular oxygen transportR-HSA-89816073 genes
- Ion channel transportR-HSA-983712185 genes
- Iron uptake and transportR-HSA-91793758 genes
- Miscellaneous transport and binding eventsR-HSA-522334529 genes
- Mitochondrial calcium ion transportR-HSA-894921523 genes
- O2/CO2 exchange in erythrocytesR-HSA-148092613 genes
- Plasma lipoprotein assembly, remodeling, and clearanceR-HSA-17482475 genes
- SLC-mediated transmembrane transportR-HSA-425407245 genes
Reactome's hierarchy is a graph rather than a tree: a pathway can sit under more than one parent, and the gene counts are each pathway's own placements at every level under it, so a parent's count is not the sum of its children's.
- Reactome, the human pathway list and hierarchy relationship file · Reactome release 97 · read · Reactome downloads"ReactomePathways.txt" and "ReactomePathwaysRelation.txt", Reactome, release 97, https://reactome.org/download-data/ (date of access 2026-09-09). Data CC0; attribution encouraged.