Skip to content

Create an account and get up to 25% off.

Order

Pathway Human Homo sapiens

Transport of small molecules

R-HSA-382551 in Reactome release 97: a top-level pathway, with 722 genes placed in it by the mapping files and 11 child pathways in the hierarchy.

The same number in the other species

Reactome writes the mouse and rat events it infers from a human pathway under the human number with the species token. A door opens only where that species' own list in this release holds the id: R-MMU-382551 (mouse), R-RNO-382551 (rat). Whether the event was inferred from this one is what the record says.

01The record

Reactome's own record of this pathway

What this tells you

The pathway list, the hierarchy and the genes on this page are read from the files Reactome publishes for Reactome release 97, built into this site on 2026-09-09: the pathway list, the hierarchy relationship file and the two gene mapping files. The record card is the one live read, Reactome's own record of this pathway.

Reactome's download page describes the mapping files: Mapping files link the source database identifier to the lowest level pathway diagram or subset of the pathway, all levels of the pathway hierarchy or database identifier to all reactions. [R13] The gene list here is the all-levels mapping of NCBI Gene ids, filled from the all-levels mapping of Ensembl ids where the NCBI file has no row for a gene; each row names which file it came from by the shape of its source id. Each row carries the evidence codes the file writes for it, as written and unranked, and both where the file writes both; no page of Reactome's documentation the survey read defines the codes, so this page does not expand them. A gene id the identity files do not name is kept as the source's own id with no door rather than turned into a symbol.

On citing what a search finds, Reactome says: It should be remembered that while we strive to contain the most current and accurate data, Reactome should not be used in citations where other primary sources of information are available. [R12] The record card prints the literature Reactome attaches to a curated pathway for that reason. The data are public domain: All data in the Reactome database and files derived from that data are licensed under the Creative Commons Public Domain Dedication (CC0). User may copy, modify, and distribute these data, even for commercial purposes, without asking for permission. Attribution is encouraged but not required. [R10] The pathway illustrations are licensed apart, under CC BY 4.0, and none is shown here.

A gene on this list is one Reactome places in this pathway in this release, and that is all the row says: it does not say the gene is expressed in a tissue or associated with a disease, which are the other two explorers' questions, read from other sources. Reactome's papers of record are [R01] [R02].

  1. [R01] Ragueneau E, Gong C, Sinquin P, Sevilla C, Beavers D, Grentner A, et al. (2026). The Reactome Knowledgebase 2026. Nucleic Acids Research 54:D673-D681. PMID 41251150, doi 10.1093/nar/gkaf1223.
  2. [R02] Milacic M, Beavers D, Conley P, Gong C, Gillespie M, Griss J, et al. (2024). The Reactome Pathway Knowledgebase 2024. Nucleic Acids Research 52:D672-D678. PMID 37941124, doi 10.1093/nar/gkad1025.
  3. [R10] Reactome, reactome.org. License Agreement. https://reactome.org/license, read 2026-09-09.
  4. [R12] Reactome, reactome.org. Citing us. https://reactome.org/cite, read 2026-09-09.
  5. [R13] Reactome, reactome.org. Download. https://reactome.org/download-data, read 2026-09-09.
Reading this pathway's record from Reactome (the pathway record).Still reading. A first read of a pathway can take a while; this page waits up to 35 seconds for it, and its scripts then bring in the panel, or a line saying what did not arrive.

02The genes

Genes Reactome places in this human pathway

The mapping files place 722 genes in this human pathway; showing 601 to 700, in pages of 100, sorted by symbol for reading. The order carries no ranking.

Genes Reactome places in this human pathway, page 7 of 8
GeneSLC5A5AuthorityHGNC:11040Mapping file id6528 NCBI fileEvidenceTAS
GeneSLC5A6AuthorityHGNC:11041Mapping file id8884 NCBI fileEvidenceTAS
GeneSLC5A7AuthorityHGNC:14025Mapping file id60482 NCBI fileEvidenceTAS
GeneSLC5A8AuthorityHGNC:19119Mapping file id160728 NCBI fileEvidenceTAS
GeneSLC5A9AuthorityHGNC:22146Mapping file id200010 NCBI fileEvidenceTAS
GeneSLC60A2AuthorityHGNC:21053Mapping file id91749 NCBI fileEvidenceTAS
GeneSLC66A1AuthorityHGNC:26001Mapping file id54896 NCBI fileEvidenceTAS
GeneSLC67A1AuthorityHGNC:10964Mapping file id5002 NCBI fileEvidenceTAS
GeneSLC6A1AuthorityHGNC:11042Mapping file id6529 NCBI fileEvidenceTAS
GeneSLC6A11AuthorityHGNC:11044Mapping file id6538 NCBI fileEvidenceTAS
GeneSLC6A12AuthorityHGNC:11045Mapping file id6539 NCBI fileEvidenceTAS
GeneSLC6A13AuthorityHGNC:11046Mapping file id6540 NCBI fileEvidenceTAS
GeneSLC6A14AuthorityHGNC:11047Mapping file id11254 NCBI fileEvidenceTAS
GeneSLC6A15AuthorityHGNC:13621Mapping file id55117 NCBI fileEvidenceTAS
GeneSLC6A19AuthorityHGNC:27960Mapping file id340024 NCBI fileEvidenceTAS
GeneSLC6A2AuthorityHGNC:11048Mapping file id6530 NCBI fileEvidenceTAS
GeneSLC6A20AuthorityHGNC:30927Mapping file id54716 NCBI fileEvidenceTAS
GeneSLC6A3AuthorityHGNC:11049Mapping file id6531 NCBI fileEvidenceTAS
GeneSLC6A4AuthorityHGNC:11050Mapping file id6532 NCBI fileEvidenceTAS
GeneSLC6A5AuthorityHGNC:11051Mapping file id9152 NCBI fileEvidenceTAS
GeneSLC6A6AuthorityHGNC:11052Mapping file id6533 NCBI fileEvidenceTAS
GeneSLC6A7AuthorityHGNC:11054Mapping file id6534 NCBI fileEvidenceTAS
GeneSLC6A9AuthorityHGNC:11056Mapping file id6536 NCBI fileEvidenceTAS
GeneSLC7A1AuthorityHGNC:11057Mapping file id6541 NCBI fileEvidenceTAS
GeneSLC7A10AuthorityHGNC:11058Mapping file id56301 NCBI fileEvidenceTAS
GeneSLC7A11AuthorityHGNC:11059Mapping file id23657 NCBI fileEvidenceTAS
GeneSLC7A2AuthorityHGNC:11060Mapping file id6542 NCBI fileEvidenceTAS
GeneSLC7A3AuthorityHGNC:11061Mapping file id84889 NCBI fileEvidenceTAS
GeneSLC7A5AuthorityHGNC:11063Mapping file id8140 NCBI fileEvidenceTAS
GeneSLC7A6AuthorityHGNC:11064Mapping file id9057 NCBI fileEvidenceTAS
GeneSLC7A7AuthorityHGNC:11065Mapping file id9056 NCBI fileEvidenceTAS
GeneSLC7A8AuthorityHGNC:11066Mapping file id23428 NCBI fileEvidenceTAS
GeneSLC7A9AuthorityHGNC:11067Mapping file id11136 NCBI fileEvidenceTAS
GeneSLC8A1AuthorityHGNC:11068Mapping file id6546 NCBI fileEvidenceTAS
GeneSLC8A2AuthorityHGNC:11069Mapping file id6543 NCBI fileEvidenceTAS
GeneSLC8A3AuthorityHGNC:11070Mapping file id6547 NCBI fileEvidenceIEA, TAS
GeneSLC8B1AuthorityHGNC:26175Mapping file id80024 NCBI fileEvidenceTAS
GeneSLC9A1AuthorityHGNC:11071Mapping file id6548 NCBI fileEvidenceTAS
GeneSLC9A2AuthorityHGNC:11072Mapping file id6549 NCBI fileEvidenceTAS
GeneSLC9A3AuthorityHGNC:11073Mapping file id6550 NCBI fileEvidenceTAS
GeneSLC9A4AuthorityHGNC:11077Mapping file id389015 NCBI fileEvidenceTAS
GeneSLC9A5AuthorityHGNC:11078Mapping file id6553 NCBI fileEvidenceTAS
GeneSLC9A6AuthorityHGNC:11079Mapping file id10479 NCBI fileEvidenceTAS
GeneSLC9A7AuthorityHGNC:17123Mapping file id84679 NCBI fileEvidenceTAS
GeneSLC9A8AuthorityHGNC:20728Mapping file id23315 NCBI fileEvidenceTAS
GeneSLC9A9AuthorityHGNC:20653Mapping file id285195 NCBI fileEvidenceTAS
GeneSLC9B1AuthorityHGNC:24244Mapping file id150159 NCBI fileEvidenceTAS
GeneSLC9B2AuthorityHGNC:25143Mapping file id133308 NCBI fileEvidenceTAS
GeneSLC9C1AuthorityHGNC:31401Mapping file id285335 NCBI fileEvidenceIEA
GeneSLC9C2AuthorityHGNC:28664Mapping file id284525 NCBI fileEvidenceTAS
GeneSLCO1A2AuthorityHGNC:10956Mapping file id6579 NCBI fileEvidenceTAS
GeneSLCO1B1AuthorityHGNC:10959Mapping file id10599 NCBI fileEvidenceTAS
GeneSLCO1B3AuthorityHGNC:10961Mapping file id28234 NCBI fileEvidenceTAS
GeneSLCO1C1AuthorityHGNC:13819Mapping file id53919 NCBI fileEvidenceTAS
GeneSLCO2A1AuthorityHGNC:10955Mapping file id6578 NCBI fileEvidenceTAS
GeneSLCO2B1AuthorityHGNC:10962Mapping file id11309 NCBI fileEvidenceTAS
GeneSLCO3A1AuthorityHGNC:10952Mapping file id28232 NCBI fileEvidenceTAS
GeneSLCO4A1AuthorityHGNC:10953Mapping file id28231 NCBI fileEvidenceTAS
GeneSLCO4C1AuthorityHGNC:23612Mapping file id353189 NCBI fileEvidenceTAS
GeneSLNAuthorityHGNC:11089Mapping file id6588 NCBI fileEvidenceTAS
GeneSMDT1AuthorityHGNC:25055Mapping file id91689 NCBI fileEvidenceTAS
GeneSOAT1AuthorityHGNC:11177Mapping file id6646 NCBI fileEvidenceTAS
GeneSOAT2AuthorityHGNC:11178Mapping file id8435 NCBI fileEvidenceTAS
GeneSPG7AuthorityHGNC:11237Mapping file id6687 NCBI fileEvidenceTAS
GeneSRIAuthorityHGNC:11292Mapping file id6717 NCBI fileEvidenceTAS
GeneSTEAP3AuthorityHGNC:24592Mapping file id55240 NCBI fileEvidenceTAS
GeneSTEAP4AuthorityHGNC:21923Mapping file id79689 NCBI fileEvidenceTAS
GeneSTOMAuthorityHGNC:3383Mapping file id2040 NCBI fileEvidenceTAS
GeneSTOML2AuthorityHGNC:14559Mapping file id30968 NCBI fileEvidenceTAS
GeneSTOML3AuthorityHGNC:19420Mapping file id161003 NCBI fileEvidenceTAS
GeneTCIRG1AuthorityHGNC:11647Mapping file id10312 NCBI fileEvidenceTAS
GeneTFAuthorityHGNC:11740Mapping file id7018 NCBI fileEvidenceTAS
GeneTFR2AuthorityHGNC:11762Mapping file id7036 NCBI fileEvidenceTAS
GeneTFRCAuthorityHGNC:11763Mapping file id7037 NCBI fileEvidenceTAS
GeneTPCN1AuthorityHGNC:18182Mapping file id53373 NCBI fileEvidenceTAS
GeneTPCN2AuthorityHGNC:20820Mapping file id219931 NCBI fileEvidenceTAS
GeneTRDNAuthorityHGNC:12261Mapping file id10345 NCBI fileEvidenceTAS
GeneTRPA1AuthorityHGNC:497Mapping file id8989 NCBI fileEvidenceTAS
GeneTRPC1AuthorityHGNC:12333Mapping file id7220 NCBI fileEvidenceTAS
GeneTRPC3AuthorityHGNC:12335Mapping file id7222 NCBI fileEvidenceTAS
GeneTRPC4AuthorityHGNC:12336Mapping file id7223 NCBI fileEvidenceTAS
GeneTRPC4APAuthorityHGNC:16181Mapping file id26133 NCBI fileEvidenceTAS
GeneTRPC5AuthorityHGNC:12337Mapping file id7224 NCBI fileEvidenceTAS
GeneTRPC6AuthorityHGNC:12338Mapping file id7225 NCBI fileEvidenceTAS
GeneTRPC7AuthorityHGNC:20754Mapping file id57113 NCBI fileEvidenceTAS
GeneTRPM1AuthorityHGNC:7146Mapping file id4308 NCBI fileEvidenceTAS
GeneTRPM2AuthorityHGNC:12339Mapping file id7226 NCBI fileEvidenceTAS
GeneTRPM3AuthorityHGNC:17992Mapping file id80036 NCBI fileEvidenceTAS
GeneTRPM4AuthorityHGNC:17993Mapping file id54795 NCBI fileEvidenceTAS
GeneTRPM5AuthorityHGNC:14323Mapping file id29850 NCBI fileEvidenceTAS
GeneTRPM6AuthorityHGNC:17995Mapping file id140803 NCBI fileEvidenceTAS
GeneTRPM7AuthorityHGNC:17994Mapping file id54822 NCBI fileEvidenceTAS
GeneTRPM8AuthorityHGNC:17961Mapping file id79054 NCBI fileEvidenceTAS
GeneTRPV1AuthorityHGNC:12716Mapping file id7442 NCBI fileEvidenceTAS
GeneTRPV2AuthorityHGNC:18082Mapping file id51393 NCBI fileEvidenceTAS
GeneTRPV3AuthorityHGNC:18084Mapping file id162514 NCBI fileEvidenceTAS
GeneTRPV4AuthorityHGNC:18083Mapping file id59341 NCBI fileEvidenceTAS
GeneTRPV5AuthorityHGNC:3145Mapping file id56302 NCBI fileEvidenceTAS
GeneTRPV6AuthorityHGNC:14006Mapping file id55503 NCBI fileEvidenceTAS
GeneTSC22D3AuthorityHGNC:3051Mapping file id1831 NCBI fileEvidenceTAS

Evidence codes on this page: IEA, TAS, as the mapping file writes them; a row carrying two was written twice by the file, once under each. The mapping file id says which file placed the gene: an NCBI Gene id from NCBI2Reactome_All_Levels.txt, an Ensembl gene id from Ensembl2Reactome_All_Levels.txt. The two files can disagree about a code, so a row's codes are the one file's view. Measured by this site's build over this release on 2026-09-09: of the 138,908 human pathway-gene pairs both files place, 207 (0.149 per cent, over 47 genes) carry TAS in the Ensembl file where the NCBI rows carry IEA alone.

  • Reactome mapping files, the human rows for this pathway · Reactome release 97 · read · Reactome downloads"NCBI2Reactome_All_Levels.txt" and "Ensembl2Reactome_All_Levels.txt", Reactome, release 97, https://reactome.org/download-data/ (date of access 2026-09-09). Data CC0; attribution encouraged.

03The hierarchy

Parents and children in this release's hierarchy

Reactome's hierarchy is a graph rather than a tree: a pathway can sit under more than one parent, and the gene counts are each pathway's own placements at every level under it, so a parent's count is not the sum of its children's.

  • Reactome, the human pathway list and hierarchy relationship file · Reactome release 97 · read · Reactome downloads"ReactomePathways.txt" and "ReactomePathwaysRelation.txt", Reactome, release 97, https://reactome.org/download-data/ (date of access 2026-09-09). Data CC0; attribution encouraged.