Pathway Human Homo sapiens
Transport of small molecules
R-HSA-382551 in Reactome release 97: a top-level pathway, with 722 genes placed in it by the mapping files and 11 child pathways in the hierarchy.
The same number in the other species
Reactome writes the mouse and rat events it infers from a human pathway under the human number with the species token. A door opens only where that species' own list in this release holds the id: R-MMU-382551 (mouse), R-RNO-382551 (rat). Whether the event was inferred from this one is what the record says.
01The record
Reactome's own record of this pathway
What this tells you
The pathway list, the hierarchy and the genes on this page are read from the files Reactome publishes for Reactome release 97, built into this site on 2026-09-09: the pathway list, the hierarchy relationship file and the two gene mapping files. The record card is the one live read, Reactome's own record of this pathway.
Reactome's download page describes the mapping files: Mapping files link the source database identifier to the lowest level pathway diagram or subset of the pathway, all levels of the pathway hierarchy or database identifier to all reactions.
[R13] The gene list here is the all-levels mapping of NCBI Gene ids, filled from the all-levels mapping of Ensembl ids where the NCBI file has no row for a gene; each row names which file it came from by the shape of its source id. Each row carries the evidence codes the file writes for it, as written and unranked, and both where the file writes both; no page of Reactome's documentation the survey read defines the codes, so this page does not expand them. A gene id the identity files do not name is kept as the source's own id with no door rather than turned into a symbol.
On citing what a search finds, Reactome says: It should be remembered that while we strive to contain the most current and accurate data, Reactome should not be used in citations where other primary sources of information are available.
[R12] The record card prints the literature Reactome attaches to a curated pathway for that reason. The data are public domain: All data in the Reactome database and files derived from that data are licensed under the Creative Commons Public Domain Dedication (CC0). User may copy, modify, and distribute these data, even for commercial purposes, without asking for permission. Attribution is encouraged but not required.
[R10] The pathway illustrations are licensed apart, under CC BY 4.0, and none is shown here.
A gene on this list is one Reactome places in this pathway in this release, and that is all the row says: it does not say the gene is expressed in a tissue or associated with a disease, which are the other two explorers' questions, read from other sources. Reactome's papers of record are [R01] [R02].
- [R01] Ragueneau E, Gong C, Sinquin P, Sevilla C, Beavers D, Grentner A, et al. (2026). The Reactome Knowledgebase 2026. Nucleic Acids Research 54:D673-D681. PMID 41251150, doi 10.1093/nar/gkaf1223.
- [R02] Milacic M, Beavers D, Conley P, Gong C, Gillespie M, Griss J, et al. (2024). The Reactome Pathway Knowledgebase 2024. Nucleic Acids Research 52:D672-D678. PMID 37941124, doi 10.1093/nar/gkad1025.
- [R10] Reactome, reactome.org. License Agreement. https://reactome.org/license, read 2026-09-09.
- [R12] Reactome, reactome.org. Citing us. https://reactome.org/cite, read 2026-09-09.
- [R13] Reactome, reactome.org. Download. https://reactome.org/download-data, read 2026-09-09.
02The genes
Genes Reactome places in this human pathway
The mapping files place 722 genes in this human pathway; showing 601 to 700, in pages of 100, sorted by symbol for reading. The order carries no ranking.
| Gene | Authority id | Mapping file id | Evidence codes |
|---|---|---|---|
| GeneSLC5A5 | AuthorityHGNC:11040 | Mapping file id6528 NCBI file | EvidenceTAS |
| GeneSLC5A6 | AuthorityHGNC:11041 | Mapping file id8884 NCBI file | EvidenceTAS |
| GeneSLC5A7 | AuthorityHGNC:14025 | Mapping file id60482 NCBI file | EvidenceTAS |
| GeneSLC5A8 | AuthorityHGNC:19119 | Mapping file id160728 NCBI file | EvidenceTAS |
| GeneSLC5A9 | AuthorityHGNC:22146 | Mapping file id200010 NCBI file | EvidenceTAS |
| GeneSLC60A2 | AuthorityHGNC:21053 | Mapping file id91749 NCBI file | EvidenceTAS |
| GeneSLC66A1 | AuthorityHGNC:26001 | Mapping file id54896 NCBI file | EvidenceTAS |
| GeneSLC67A1 | AuthorityHGNC:10964 | Mapping file id5002 NCBI file | EvidenceTAS |
| GeneSLC6A1 | AuthorityHGNC:11042 | Mapping file id6529 NCBI file | EvidenceTAS |
| GeneSLC6A11 | AuthorityHGNC:11044 | Mapping file id6538 NCBI file | EvidenceTAS |
| GeneSLC6A12 | AuthorityHGNC:11045 | Mapping file id6539 NCBI file | EvidenceTAS |
| GeneSLC6A13 | AuthorityHGNC:11046 | Mapping file id6540 NCBI file | EvidenceTAS |
| GeneSLC6A14 | AuthorityHGNC:11047 | Mapping file id11254 NCBI file | EvidenceTAS |
| GeneSLC6A15 | AuthorityHGNC:13621 | Mapping file id55117 NCBI file | EvidenceTAS |
| GeneSLC6A19 | AuthorityHGNC:27960 | Mapping file id340024 NCBI file | EvidenceTAS |
| GeneSLC6A2 | AuthorityHGNC:11048 | Mapping file id6530 NCBI file | EvidenceTAS |
| GeneSLC6A20 | AuthorityHGNC:30927 | Mapping file id54716 NCBI file | EvidenceTAS |
| GeneSLC6A3 | AuthorityHGNC:11049 | Mapping file id6531 NCBI file | EvidenceTAS |
| GeneSLC6A4 | AuthorityHGNC:11050 | Mapping file id6532 NCBI file | EvidenceTAS |
| GeneSLC6A5 | AuthorityHGNC:11051 | Mapping file id9152 NCBI file | EvidenceTAS |
| GeneSLC6A6 | AuthorityHGNC:11052 | Mapping file id6533 NCBI file | EvidenceTAS |
| GeneSLC6A7 | AuthorityHGNC:11054 | Mapping file id6534 NCBI file | EvidenceTAS |
| GeneSLC6A9 | AuthorityHGNC:11056 | Mapping file id6536 NCBI file | EvidenceTAS |
| GeneSLC7A1 | AuthorityHGNC:11057 | Mapping file id6541 NCBI file | EvidenceTAS |
| GeneSLC7A10 | AuthorityHGNC:11058 | Mapping file id56301 NCBI file | EvidenceTAS |
| GeneSLC7A11 | AuthorityHGNC:11059 | Mapping file id23657 NCBI file | EvidenceTAS |
| GeneSLC7A2 | AuthorityHGNC:11060 | Mapping file id6542 NCBI file | EvidenceTAS |
| GeneSLC7A3 | AuthorityHGNC:11061 | Mapping file id84889 NCBI file | EvidenceTAS |
| GeneSLC7A5 | AuthorityHGNC:11063 | Mapping file id8140 NCBI file | EvidenceTAS |
| GeneSLC7A6 | AuthorityHGNC:11064 | Mapping file id9057 NCBI file | EvidenceTAS |
| GeneSLC7A7 | AuthorityHGNC:11065 | Mapping file id9056 NCBI file | EvidenceTAS |
| GeneSLC7A8 | AuthorityHGNC:11066 | Mapping file id23428 NCBI file | EvidenceTAS |
| GeneSLC7A9 | AuthorityHGNC:11067 | Mapping file id11136 NCBI file | EvidenceTAS |
| GeneSLC8A1 | AuthorityHGNC:11068 | Mapping file id6546 NCBI file | EvidenceTAS |
| GeneSLC8A2 | AuthorityHGNC:11069 | Mapping file id6543 NCBI file | EvidenceTAS |
| GeneSLC8A3 | AuthorityHGNC:11070 | Mapping file id6547 NCBI file | EvidenceIEA, TAS |
| GeneSLC8B1 | AuthorityHGNC:26175 | Mapping file id80024 NCBI file | EvidenceTAS |
| GeneSLC9A1 | AuthorityHGNC:11071 | Mapping file id6548 NCBI file | EvidenceTAS |
| GeneSLC9A2 | AuthorityHGNC:11072 | Mapping file id6549 NCBI file | EvidenceTAS |
| GeneSLC9A3 | AuthorityHGNC:11073 | Mapping file id6550 NCBI file | EvidenceTAS |
| GeneSLC9A4 | AuthorityHGNC:11077 | Mapping file id389015 NCBI file | EvidenceTAS |
| GeneSLC9A5 | AuthorityHGNC:11078 | Mapping file id6553 NCBI file | EvidenceTAS |
| GeneSLC9A6 | AuthorityHGNC:11079 | Mapping file id10479 NCBI file | EvidenceTAS |
| GeneSLC9A7 | AuthorityHGNC:17123 | Mapping file id84679 NCBI file | EvidenceTAS |
| GeneSLC9A8 | AuthorityHGNC:20728 | Mapping file id23315 NCBI file | EvidenceTAS |
| GeneSLC9A9 | AuthorityHGNC:20653 | Mapping file id285195 NCBI file | EvidenceTAS |
| GeneSLC9B1 | AuthorityHGNC:24244 | Mapping file id150159 NCBI file | EvidenceTAS |
| GeneSLC9B2 | AuthorityHGNC:25143 | Mapping file id133308 NCBI file | EvidenceTAS |
| GeneSLC9C1 | AuthorityHGNC:31401 | Mapping file id285335 NCBI file | EvidenceIEA |
| GeneSLC9C2 | AuthorityHGNC:28664 | Mapping file id284525 NCBI file | EvidenceTAS |
| GeneSLCO1A2 | AuthorityHGNC:10956 | Mapping file id6579 NCBI file | EvidenceTAS |
| GeneSLCO1B1 | AuthorityHGNC:10959 | Mapping file id10599 NCBI file | EvidenceTAS |
| GeneSLCO1B3 | AuthorityHGNC:10961 | Mapping file id28234 NCBI file | EvidenceTAS |
| GeneSLCO1C1 | AuthorityHGNC:13819 | Mapping file id53919 NCBI file | EvidenceTAS |
| GeneSLCO2A1 | AuthorityHGNC:10955 | Mapping file id6578 NCBI file | EvidenceTAS |
| GeneSLCO2B1 | AuthorityHGNC:10962 | Mapping file id11309 NCBI file | EvidenceTAS |
| GeneSLCO3A1 | AuthorityHGNC:10952 | Mapping file id28232 NCBI file | EvidenceTAS |
| GeneSLCO4A1 | AuthorityHGNC:10953 | Mapping file id28231 NCBI file | EvidenceTAS |
| GeneSLCO4C1 | AuthorityHGNC:23612 | Mapping file id353189 NCBI file | EvidenceTAS |
| GeneSLN | AuthorityHGNC:11089 | Mapping file id6588 NCBI file | EvidenceTAS |
| GeneSMDT1 | AuthorityHGNC:25055 | Mapping file id91689 NCBI file | EvidenceTAS |
| GeneSOAT1 | AuthorityHGNC:11177 | Mapping file id6646 NCBI file | EvidenceTAS |
| GeneSOAT2 | AuthorityHGNC:11178 | Mapping file id8435 NCBI file | EvidenceTAS |
| GeneSPG7 | AuthorityHGNC:11237 | Mapping file id6687 NCBI file | EvidenceTAS |
| GeneSRI | AuthorityHGNC:11292 | Mapping file id6717 NCBI file | EvidenceTAS |
| GeneSTEAP3 | AuthorityHGNC:24592 | Mapping file id55240 NCBI file | EvidenceTAS |
| GeneSTEAP4 | AuthorityHGNC:21923 | Mapping file id79689 NCBI file | EvidenceTAS |
| GeneSTOM | AuthorityHGNC:3383 | Mapping file id2040 NCBI file | EvidenceTAS |
| GeneSTOML2 | AuthorityHGNC:14559 | Mapping file id30968 NCBI file | EvidenceTAS |
| GeneSTOML3 | AuthorityHGNC:19420 | Mapping file id161003 NCBI file | EvidenceTAS |
| GeneTCIRG1 | AuthorityHGNC:11647 | Mapping file id10312 NCBI file | EvidenceTAS |
| GeneTF | AuthorityHGNC:11740 | Mapping file id7018 NCBI file | EvidenceTAS |
| GeneTFR2 | AuthorityHGNC:11762 | Mapping file id7036 NCBI file | EvidenceTAS |
| GeneTFRC | AuthorityHGNC:11763 | Mapping file id7037 NCBI file | EvidenceTAS |
| GeneTPCN1 | AuthorityHGNC:18182 | Mapping file id53373 NCBI file | EvidenceTAS |
| GeneTPCN2 | AuthorityHGNC:20820 | Mapping file id219931 NCBI file | EvidenceTAS |
| GeneTRDN | AuthorityHGNC:12261 | Mapping file id10345 NCBI file | EvidenceTAS |
| GeneTRPA1 | AuthorityHGNC:497 | Mapping file id8989 NCBI file | EvidenceTAS |
| GeneTRPC1 | AuthorityHGNC:12333 | Mapping file id7220 NCBI file | EvidenceTAS |
| GeneTRPC3 | AuthorityHGNC:12335 | Mapping file id7222 NCBI file | EvidenceTAS |
| GeneTRPC4 | AuthorityHGNC:12336 | Mapping file id7223 NCBI file | EvidenceTAS |
| GeneTRPC4AP | AuthorityHGNC:16181 | Mapping file id26133 NCBI file | EvidenceTAS |
| GeneTRPC5 | AuthorityHGNC:12337 | Mapping file id7224 NCBI file | EvidenceTAS |
| GeneTRPC6 | AuthorityHGNC:12338 | Mapping file id7225 NCBI file | EvidenceTAS |
| GeneTRPC7 | AuthorityHGNC:20754 | Mapping file id57113 NCBI file | EvidenceTAS |
| GeneTRPM1 | AuthorityHGNC:7146 | Mapping file id4308 NCBI file | EvidenceTAS |
| GeneTRPM2 | AuthorityHGNC:12339 | Mapping file id7226 NCBI file | EvidenceTAS |
| GeneTRPM3 | AuthorityHGNC:17992 | Mapping file id80036 NCBI file | EvidenceTAS |
| GeneTRPM4 | AuthorityHGNC:17993 | Mapping file id54795 NCBI file | EvidenceTAS |
| GeneTRPM5 | AuthorityHGNC:14323 | Mapping file id29850 NCBI file | EvidenceTAS |
| GeneTRPM6 | AuthorityHGNC:17995 | Mapping file id140803 NCBI file | EvidenceTAS |
| GeneTRPM7 | AuthorityHGNC:17994 | Mapping file id54822 NCBI file | EvidenceTAS |
| GeneTRPM8 | AuthorityHGNC:17961 | Mapping file id79054 NCBI file | EvidenceTAS |
| GeneTRPV1 | AuthorityHGNC:12716 | Mapping file id7442 NCBI file | EvidenceTAS |
| GeneTRPV2 | AuthorityHGNC:18082 | Mapping file id51393 NCBI file | EvidenceTAS |
| GeneTRPV3 | AuthorityHGNC:18084 | Mapping file id162514 NCBI file | EvidenceTAS |
| GeneTRPV4 | AuthorityHGNC:18083 | Mapping file id59341 NCBI file | EvidenceTAS |
| GeneTRPV5 | AuthorityHGNC:3145 | Mapping file id56302 NCBI file | EvidenceTAS |
| GeneTRPV6 | AuthorityHGNC:14006 | Mapping file id55503 NCBI file | EvidenceTAS |
| GeneTSC22D3 | AuthorityHGNC:3051 | Mapping file id1831 NCBI file | EvidenceTAS |
Evidence codes on this page: IEA, TAS, as the mapping file writes them; a row carrying two was written twice by the file, once under each. The mapping file id says which file placed the gene: an NCBI Gene id from NCBI2Reactome_All_Levels.txt, an Ensembl gene id from Ensembl2Reactome_All_Levels.txt. The two files can disagree about a code, so a row's codes are the one file's view. Measured by this site's build over this release on 2026-09-09: of the 138,908 human pathway-gene pairs both files place, 207 (0.149 per cent, over 47 genes) carry TAS in the Ensembl file where the NCBI rows carry IEA alone.
- Reactome mapping files, the human rows for this pathway · Reactome release 97 · read · Reactome downloads"NCBI2Reactome_All_Levels.txt" and "Ensembl2Reactome_All_Levels.txt", Reactome, release 97, https://reactome.org/download-data/ (date of access 2026-09-09). Data CC0; attribution encouraged.
03The hierarchy
Parents and children in this release's hierarchy
Parents
None: this is a top-level pathway of the release.
Children
- ABC-family protein mediated transportR-HSA-38255690 genes
- Aquaporin-mediated transportR-HSA-44571752 genes
- Glycosphingolipid transportR-HSA-98455768 genes
- Intracellular oxygen transportR-HSA-89816073 genes
- Ion channel transportR-HSA-983712185 genes
- Iron uptake and transportR-HSA-91793758 genes
- Miscellaneous transport and binding eventsR-HSA-522334529 genes
- Mitochondrial calcium ion transportR-HSA-894921523 genes
- O2/CO2 exchange in erythrocytesR-HSA-148092613 genes
- Plasma lipoprotein assembly, remodeling, and clearanceR-HSA-17482475 genes
- SLC-mediated transmembrane transportR-HSA-425407245 genes
Reactome's hierarchy is a graph rather than a tree: a pathway can sit under more than one parent, and the gene counts are each pathway's own placements at every level under it, so a parent's count is not the sum of its children's.
- Reactome, the human pathway list and hierarchy relationship file · Reactome release 97 · read · Reactome downloads"ReactomePathways.txt" and "ReactomePathwaysRelation.txt", Reactome, release 97, https://reactome.org/download-data/ (date of access 2026-09-09). Data CC0; attribution encouraged.