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Pathway Human Homo sapiens

Metabolism of carbohydrates and carbohydrate derivatives

R-HSA-71387 in Reactome release 97: under Metabolism, with 300 genes placed in it by the mapping files and 10 child pathways in the hierarchy.

The same number in the other species

Reactome writes the mouse and rat events it infers from a human pathway under the human number with the species token. A door opens only where that species' own list in this release holds the id: R-MMU-71387 (mouse), R-RNO-71387 (rat). Whether the event was inferred from this one is what the record says.

01The record

Reactome's own record of this pathway

What this tells you

The pathway list, the hierarchy and the genes on this page are read from the files Reactome publishes for Reactome release 97, built into this site on 2026-09-09: the pathway list, the hierarchy relationship file and the two gene mapping files. The record card is the one live read, Reactome's own record of this pathway.

Reactome's download page describes the mapping files: Mapping files link the source database identifier to the lowest level pathway diagram or subset of the pathway, all levels of the pathway hierarchy or database identifier to all reactions. [R13] The gene list here is the all-levels mapping of NCBI Gene ids, filled from the all-levels mapping of Ensembl ids where the NCBI file has no row for a gene; each row names which file it came from by the shape of its source id. Each row carries the evidence codes the file writes for it, as written and unranked, and both where the file writes both; no page of Reactome's documentation the survey read defines the codes, so this page does not expand them. A gene id the identity files do not name is kept as the source's own id with no door rather than turned into a symbol.

On citing what a search finds, Reactome says: It should be remembered that while we strive to contain the most current and accurate data, Reactome should not be used in citations where other primary sources of information are available. [R12] The record card prints the literature Reactome attaches to a curated pathway for that reason. The data are public domain: All data in the Reactome database and files derived from that data are licensed under the Creative Commons Public Domain Dedication (CC0). User may copy, modify, and distribute these data, even for commercial purposes, without asking for permission. Attribution is encouraged but not required. [R10] The pathway illustrations are licensed apart, under CC BY 4.0, and none is shown here.

A gene on this list is one Reactome places in this pathway in this release, and that is all the row says: it does not say the gene is expressed in a tissue or associated with a disease, which are the other two explorers' questions, read from other sources. Reactome's papers of record are [R01] [R02].

  1. [R01] Ragueneau E, Gong C, Sinquin P, Sevilla C, Beavers D, Grentner A, et al. (2026). The Reactome Knowledgebase 2026. Nucleic Acids Research 54:D673-D681. PMID 41251150, doi 10.1093/nar/gkaf1223.
  2. [R02] Milacic M, Beavers D, Conley P, Gong C, Gillespie M, Griss J, et al. (2024). The Reactome Pathway Knowledgebase 2024. Nucleic Acids Research 52:D672-D678. PMID 37941124, doi 10.1093/nar/gkad1025.
  3. [R10] Reactome, reactome.org. License Agreement. https://reactome.org/license, read 2026-09-09.
  4. [R12] Reactome, reactome.org. Citing us. https://reactome.org/cite, read 2026-09-09.
  5. [R13] Reactome, reactome.org. Download. https://reactome.org/download-data, read 2026-09-09.
Reading this pathway's record from Reactome (the pathway record).Still reading. A first read of a pathway can take a while; this page waits up to 35 seconds for it, and its scripts then bring in the panel, or a line saying what did not arrive.

02The genes

Genes Reactome places in this human pathway

The mapping files place 300 genes in this human pathway; showing 1 to 100, in pages of 100, sorted by symbol for reading. The order carries no ranking.

Genes Reactome places in this human pathway, page 1 of 3
GeneAAASAuthorityHGNC:13666Mapping file id8086 NCBI fileEvidenceTAS
GeneABCC5AuthorityHGNC:56Mapping file id10057 NCBI fileEvidenceTAS
GeneABOAuthorityHGNC:79Mapping file id28 NCBI fileEvidenceTAS
GeneACANAuthorityHGNC:319Mapping file id176 NCBI fileEvidenceTAS
GeneADPGKAuthorityHGNC:25250Mapping file id83440 NCBI fileEvidenceTAS
GeneAGLAuthorityHGNC:321Mapping file id178 NCBI fileEvidenceTAS
GeneAGRNAuthorityHGNC:329Mapping file id375790 NCBI fileEvidenceIEA, TAS
GeneAKR1A1AuthorityHGNC:380Mapping file id10327 NCBI fileEvidenceTAS
GeneAKR1B1AuthorityHGNC:381Mapping file id231 NCBI fileEvidenceIEA, TAS
GeneAKR1E2AuthorityHGNC:23437Mapping file id83592 NCBI fileEvidenceTAS
GeneALDH1A1AuthorityHGNC:402Mapping file id216 NCBI fileEvidenceTAS
GeneALDOAAuthorityHGNC:414Mapping file id226 NCBI fileEvidenceTAS
GeneALDOBAuthorityHGNC:417Mapping file id229 NCBI fileEvidenceTAS
GeneALDOCAuthorityHGNC:418Mapping file id230 NCBI fileEvidenceTAS
GeneARSBAuthorityHGNC:714Mapping file id411 NCBI fileEvidenceTAS
GeneB3GALT1AuthorityHGNC:916Mapping file id8708 NCBI fileEvidenceTAS
GeneB3GALT2AuthorityHGNC:917Mapping file id8707 NCBI fileEvidenceTAS
GeneB3GALT4AuthorityHGNC:919Mapping file id8705 NCBI fileEvidenceTAS
GeneB3GALT5AuthorityHGNC:920Mapping file id10317 NCBI fileEvidenceTAS
GeneB3GALT6AuthorityHGNC:17978Mapping file id126792 NCBI fileEvidenceTAS
GeneB3GAT1AuthorityHGNC:921Mapping file id27087 NCBI fileEvidenceTAS
GeneB3GAT2AuthorityHGNC:922Mapping file id135152 NCBI fileEvidenceTAS
GeneB3GAT3AuthorityHGNC:923Mapping file id26229 NCBI fileEvidenceTAS
GeneB3GNT2AuthorityHGNC:15629Mapping file id10678 NCBI fileEvidenceTAS
GeneB3GNT3AuthorityHGNC:13528Mapping file id10331 NCBI fileEvidenceTAS
GeneB3GNT4AuthorityHGNC:15683Mapping file id79369 NCBI fileEvidenceTAS
GeneB3GNT7AuthorityHGNC:18811Mapping file id93010 NCBI fileEvidenceTAS
GeneB4GALNT2AuthorityHGNC:24136Mapping file id124872 NCBI fileEvidenceTAS
GeneB4GALT1AuthorityHGNC:924Mapping file id2683 NCBI fileEvidenceTAS
GeneB4GALT2AuthorityHGNC:925Mapping file id8704 NCBI fileEvidenceTAS
GeneB4GALT3AuthorityHGNC:926Mapping file id8703 NCBI fileEvidenceTAS
GeneB4GALT4AuthorityHGNC:927Mapping file id8702 NCBI fileEvidenceTAS
GeneB4GALT5AuthorityHGNC:928Mapping file id9334 NCBI fileEvidenceTAS
GeneB4GALT6AuthorityHGNC:929Mapping file id9331 NCBI fileEvidenceTAS
GeneB4GALT7AuthorityHGNC:930Mapping file id11285 NCBI fileEvidenceTAS
GeneB4GAT1AuthorityHGNC:15685Mapping file id11041 NCBI fileEvidenceTAS
GeneBCANAuthorityHGNC:23059Mapping file id63827 NCBI fileEvidenceTAS
GeneBGNAuthorityHGNC:1044Mapping file id633 NCBI fileEvidenceTAS
GeneBPGMAuthorityHGNC:1093Mapping file id669 NCBI fileEvidenceTAS
GeneCALM1AuthorityHGNC:1442Mapping file id801 NCBI fileEvidenceIEA, TAS
GeneCALM2AuthorityHGNC:1445Mapping file id805 NCBI fileEvidenceIEA, TAS
GeneCALM3AuthorityHGNC:1449Mapping file id808 NCBI fileEvidenceIEA, TAS
GeneCD44AuthorityHGNC:1681Mapping file id960 NCBI fileEvidenceTAS
GeneCEMIPAuthorityHGNC:29213Mapping file id57214 NCBI fileEvidenceTAS
GeneCHP1AuthorityHGNC:17433Mapping file id11261 NCBI fileEvidenceTAS
GeneCHPFAuthorityHGNC:24291Mapping file id79586 NCBI fileEvidenceTAS
GeneCHPF2AuthorityHGNC:29270Mapping file id54480 NCBI fileEvidenceTAS
GeneCHST1AuthorityHGNC:1969Mapping file id8534 NCBI fileEvidenceTAS
GeneCHST11AuthorityHGNC:17422Mapping file id50515 NCBI fileEvidenceTAS
GeneCHST12AuthorityHGNC:17423Mapping file id55501 NCBI fileEvidenceTAS
GeneCHST13AuthorityHGNC:21755Mapping file id166012 NCBI fileEvidenceTAS
GeneCHST14AuthorityHGNC:24464Mapping file id113189 NCBI fileEvidenceTAS
GeneCHST15AuthorityHGNC:18137Mapping file id51363 NCBI fileEvidenceTAS
GeneCHST2AuthorityHGNC:1970Mapping file id9435 NCBI fileEvidenceTAS
GeneCHST3AuthorityHGNC:1971Mapping file id9469 NCBI fileEvidenceTAS
GeneCHST5AuthorityHGNC:1973Mapping file id23563 NCBI fileEvidenceTAS
GeneCHST6AuthorityHGNC:6938Mapping file id4166 NCBI fileEvidenceTAS
GeneCHST7AuthorityHGNC:13817Mapping file id56548 NCBI fileEvidenceTAS
GeneCHST9AuthorityHGNC:19898Mapping file id83539 NCBI fileEvidenceTAS
GeneCHSY1AuthorityHGNC:17198Mapping file id22856 NCBI fileEvidenceTAS
GeneCHSY3AuthorityHGNC:24293Mapping file id337876 NCBI fileEvidenceTAS
GeneCRYL1AuthorityHGNC:18246Mapping file id51084 NCBI fileEvidenceTAS
GeneCSGALNACT1AuthorityHGNC:24290Mapping file id55790 NCBI fileEvidenceTAS
GeneCSGALNACT2AuthorityHGNC:24292Mapping file id55454 NCBI fileEvidenceTAS
GeneCSPG4AuthorityHGNC:2466Mapping file id1464 NCBI fileEvidenceTAS
GeneCSPG5AuthorityHGNC:2467Mapping file id10675 NCBI fileEvidenceTAS
GeneCTSLAuthorityHGNC:2537Mapping file id1514 NCBI fileEvidenceTAS
GeneDCNAuthorityHGNC:2705Mapping file id1634 NCBI fileEvidenceTAS
GeneDCXRAuthorityHGNC:18985Mapping file id51181 NCBI fileEvidenceTAS
GeneDERAAuthorityHGNC:24269Mapping file id51071 NCBI fileEvidenceTAS
GeneDSEAuthorityHGNC:21144Mapping file id29940 NCBI fileEvidenceTAS
GeneDSELAuthorityHGNC:18144Mapping file id92126 NCBI fileEvidenceTAS
GeneENO1AuthorityHGNC:3350Mapping file id2023 NCBI fileEvidenceTAS
GeneENO2AuthorityHGNC:3353Mapping file id2026 NCBI fileEvidenceTAS
GeneENO3AuthorityHGNC:3354Mapping file id2027 NCBI fileEvidenceTAS
GeneENO4AuthorityHGNC:31670Mapping file id387712 NCBI fileEvidenceTAS
GeneEPM2AAuthorityHGNC:3413Mapping file id7957 NCBI fileEvidenceTAS
GeneEXT1AuthorityHGNC:3512Mapping file id2131 NCBI fileEvidenceTAS
GeneEXT2AuthorityHGNC:3513Mapping file id2132 NCBI fileEvidenceTAS
GeneEXTL2AuthorityHGNC:3516Mapping file id2135 NCBI fileEvidenceTAS
GeneEXTL3AuthorityHGNC:3518Mapping file id2137 NCBI fileEvidenceTAS
GeneFAM20BAuthorityHGNC:23017Mapping file id9917 NCBI fileEvidenceTAS
GeneFBP1AuthorityHGNC:3606Mapping file id2203 NCBI fileEvidenceTAS
GeneFBP2AuthorityHGNC:3607Mapping file id8789 NCBI fileEvidenceTAS
GeneFMODAuthorityHGNC:3774Mapping file id2331 NCBI fileEvidenceTAS
GeneFUT1AuthorityHGNC:4012Mapping file id2523 NCBI fileEvidenceTAS
GeneFUT2AuthorityHGNC:4013Mapping file id2524 NCBI fileEvidenceTAS
GeneFUT3AuthorityHGNC:4014Mapping file id2525 NCBI fileEvidenceTAS
GeneFUT4AuthorityHGNC:4015Mapping file id2526 NCBI fileEvidenceTAS
GeneFUT5AuthorityHGNC:4016Mapping file id2527 NCBI fileEvidenceTAS
GeneFUT6AuthorityHGNC:4017Mapping file id2528 NCBI fileEvidenceTAS
GeneFUT7AuthorityHGNC:4018Mapping file id2529 NCBI fileEvidenceTAS
GeneFUT9AuthorityHGNC:4020Mapping file id10690 NCBI fileEvidenceTAS
GeneG6PC1AuthorityHGNC:4056Mapping file id2538 NCBI fileEvidenceTAS
GeneG6PC2AuthorityHGNC:28906Mapping file id57818 NCBI fileEvidenceTAS
GeneG6PC3AuthorityHGNC:24861Mapping file id92579 NCBI fileEvidenceTAS
GeneG6PDAuthorityHGNC:4057Mapping file id2539 NCBI fileEvidenceTAS
GeneGAAAuthorityHGNC:4065Mapping file id2548 NCBI fileEvidenceTAS
GeneGALEAuthorityHGNC:4116Mapping file id2582 NCBI fileEvidenceTAS
GeneGALK1AuthorityHGNC:4118Mapping file id2584 NCBI fileEvidenceTAS

Evidence codes on this page: IEA, TAS, as the mapping file writes them; a row carrying two was written twice by the file, once under each. The mapping file id says which file placed the gene: an NCBI Gene id from NCBI2Reactome_All_Levels.txt, an Ensembl gene id from Ensembl2Reactome_All_Levels.txt. The two files can disagree about a code, so a row's codes are the one file's view. Measured by this site's build over this release on 2026-09-09: of the 138,908 human pathway-gene pairs both files place, 207 (0.149 per cent, over 47 genes) carry TAS in the Ensembl file where the NCBI rows carry IEA alone.

  • Reactome mapping files, the human rows for this pathway · Reactome release 97 · read · Reactome downloads"NCBI2Reactome_All_Levels.txt" and "Ensembl2Reactome_All_Levels.txt", Reactome, release 97, https://reactome.org/download-data/ (date of access 2026-09-09). Data CC0; attribution encouraged.

03The hierarchy

Parents and children in this release's hierarchy

Reactome's hierarchy is a graph rather than a tree: a pathway can sit under more than one parent, and the gene counts are each pathway's own placements at every level under it, so a parent's count is not the sum of its children's.

  • Reactome, the human pathway list and hierarchy relationship file · Reactome release 97 · read · Reactome downloads"ReactomePathways.txt" and "ReactomePathwaysRelation.txt", Reactome, release 97, https://reactome.org/download-data/ (date of access 2026-09-09). Data CC0; attribution encouraged.