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Pathway Human Homo sapiens

Metabolism of carbohydrates and carbohydrate derivatives

R-HSA-71387 in Reactome release 97: under Metabolism, with 300 genes placed in it by the mapping files and 10 child pathways in the hierarchy.

The same number in the other species

Reactome writes the mouse and rat events it infers from a human pathway under the human number with the species token. A door opens only where that species' own list in this release holds the id: R-MMU-71387 (mouse), R-RNO-71387 (rat). Whether the event was inferred from this one is what the record says.

01The record

Reactome's own record of this pathway

What this tells you

The pathway list, the hierarchy and the genes on this page are read from the files Reactome publishes for Reactome release 97, built into this site on 2026-09-09: the pathway list, the hierarchy relationship file and the two gene mapping files. The record card is the one live read, Reactome's own record of this pathway.

Reactome's download page describes the mapping files: Mapping files link the source database identifier to the lowest level pathway diagram or subset of the pathway, all levels of the pathway hierarchy or database identifier to all reactions. [R13] The gene list here is the all-levels mapping of NCBI Gene ids, filled from the all-levels mapping of Ensembl ids where the NCBI file has no row for a gene; each row names which file it came from by the shape of its source id. Each row carries the evidence codes the file writes for it, as written and unranked, and both where the file writes both; no page of Reactome's documentation the survey read defines the codes, so this page does not expand them. A gene id the identity files do not name is kept as the source's own id with no door rather than turned into a symbol.

On citing what a search finds, Reactome says: It should be remembered that while we strive to contain the most current and accurate data, Reactome should not be used in citations where other primary sources of information are available. [R12] The record card prints the literature Reactome attaches to a curated pathway for that reason. The data are public domain: All data in the Reactome database and files derived from that data are licensed under the Creative Commons Public Domain Dedication (CC0). User may copy, modify, and distribute these data, even for commercial purposes, without asking for permission. Attribution is encouraged but not required. [R10] The pathway illustrations are licensed apart, under CC BY 4.0, and none is shown here.

A gene on this list is one Reactome places in this pathway in this release, and that is all the row says: it does not say the gene is expressed in a tissue or associated with a disease, which are the other two explorers' questions, read from other sources. Reactome's papers of record are [R01] [R02].

  1. [R01] Ragueneau E, Gong C, Sinquin P, Sevilla C, Beavers D, Grentner A, et al. (2026). The Reactome Knowledgebase 2026. Nucleic Acids Research 54:D673-D681. PMID 41251150, doi 10.1093/nar/gkaf1223.
  2. [R02] Milacic M, Beavers D, Conley P, Gong C, Gillespie M, Griss J, et al. (2024). The Reactome Pathway Knowledgebase 2024. Nucleic Acids Research 52:D672-D678. PMID 37941124, doi 10.1093/nar/gkad1025.
  3. [R10] Reactome, reactome.org. License Agreement. https://reactome.org/license, read 2026-09-09.
  4. [R12] Reactome, reactome.org. Citing us. https://reactome.org/cite, read 2026-09-09.
  5. [R13] Reactome, reactome.org. Download. https://reactome.org/download-data, read 2026-09-09.
Reading this pathway's record from Reactome (the pathway record).Still reading. A first read of a pathway can take a while; this page waits up to 35 seconds for it, and its scripts then bring in the panel, or a line saying what did not arrive.

02The genes

Genes Reactome places in this human pathway

The mapping files place 300 genes in this human pathway; showing 101 to 200, in pages of 100, sorted by symbol for reading. The order carries no ranking.

Genes Reactome places in this human pathway, page 2 of 3
GeneGALMAuthorityHGNC:24063Mapping file id130589 NCBI fileEvidenceTAS
GeneGALNSAuthorityHGNC:4122Mapping file id2588 NCBI fileEvidenceTAS
GeneGALTAuthorityHGNC:4135Mapping file id2592 NCBI fileEvidenceTAS
GeneGAPDHAuthorityHGNC:4141Mapping file id2597 NCBI fileEvidenceTAS
GeneGAPDHSAuthorityHGNC:24864Mapping file id26330 NCBI fileEvidenceTAS
GeneGBE1AuthorityHGNC:4180Mapping file id2632 NCBI fileEvidenceTAS
GeneGCKAuthorityHGNC:4195Mapping file id2645 NCBI fileEvidenceTAS
GeneGCKRAuthorityHGNC:4196Mapping file id2646 NCBI fileEvidenceTAS
GeneGLB1AuthorityHGNC:4298Mapping file id2720 NCBI fileEvidenceTAS
GeneGLB1LAuthorityHGNC:28129Mapping file id79411 NCBI fileEvidenceTAS
GeneGLB1L2AuthorityHGNC:25129Mapping file id89944 NCBI fileEvidenceTAS
GeneGLB1L3AuthorityHGNC:25147Mapping file id112937 NCBI fileEvidenceTAS
GeneGLCEAuthorityHGNC:17855Mapping file id26035 NCBI fileEvidenceIEA
GeneGLYCTKAuthorityHGNC:24247Mapping file id132158 NCBI fileEvidenceTAS
GeneGNPDA1AuthorityHGNC:4417Mapping file id10007 NCBI fileEvidenceTAS
GeneGNPDA2AuthorityHGNC:21526Mapping file id132789 NCBI fileEvidenceTAS
GeneGNSAuthorityHGNC:4422Mapping file id2799 NCBI fileEvidenceTAS
GeneGPC1AuthorityHGNC:4449Mapping file id2817 NCBI fileEvidenceIEA, TAS
GeneGPC2AuthorityHGNC:4450Mapping file id221914 NCBI fileEvidenceIEA, TAS
GeneGPC3AuthorityHGNC:4451Mapping file id2719 NCBI fileEvidenceIEA, TAS
GeneGPC4AuthorityHGNC:4452Mapping file id2239 NCBI fileEvidenceIEA, TAS
GeneGPC5AuthorityHGNC:4453Mapping file id2262 NCBI fileEvidenceIEA, TAS
GeneGPC6AuthorityHGNC:4454Mapping file id10082 NCBI fileEvidenceIEA, TAS
GeneGPIAuthorityHGNC:4458Mapping file id2821 NCBI fileEvidenceTAS
GeneGUSBAuthorityHGNC:4696Mapping file id2990 NCBI fileEvidenceTAS
GeneGYG1AuthorityHGNC:4699Mapping file id2992 NCBI fileEvidenceIEA, TAS
GeneGYG2AuthorityHGNC:4700Mapping file id8908 NCBI fileEvidenceTAS
GeneGYS1AuthorityHGNC:4706Mapping file id2997 NCBI fileEvidenceTAS
GeneGYS2AuthorityHGNC:4707Mapping file id2998 NCBI fileEvidenceTAS
GeneHAS1AuthorityHGNC:4818Mapping file id3036 NCBI fileEvidenceTAS
GeneHAS2AuthorityHGNC:4819Mapping file id3037 NCBI fileEvidenceTAS
GeneHAS3AuthorityHGNC:4820Mapping file id3038 NCBI fileEvidenceTAS
GeneHEXAAuthorityHGNC:4878Mapping file id3073 NCBI fileEvidenceTAS
GeneHEXBAuthorityHGNC:4879Mapping file id3074 NCBI fileEvidenceTAS
GeneHGSNATAuthorityHGNC:26527Mapping file id138050 NCBI fileEvidenceTAS
GeneHK1AuthorityHGNC:4922Mapping file id3098 NCBI fileEvidenceTAS
GeneHK2AuthorityHGNC:4923Mapping file id3099 NCBI fileEvidenceTAS
GeneHK3AuthorityHGNC:4925Mapping file id3101 NCBI fileEvidenceTAS
GeneHKDC1AuthorityHGNC:23302Mapping file id80201 NCBI fileEvidenceTAS
GeneHMMRAuthorityHGNC:5012Mapping file id3161 NCBI fileEvidenceTAS
GeneHPSEAuthorityHGNC:5164Mapping file id10855 NCBI fileEvidenceTAS
GeneHPSE2AuthorityHGNC:18374Mapping file id60495 NCBI fileEvidenceTAS
GeneHS2ST1AuthorityHGNC:5193Mapping file id9653 NCBI fileEvidenceTAS
GeneHS3ST1AuthorityHGNC:5194Mapping file id9957 NCBI fileEvidenceTAS
GeneHS3ST2AuthorityHGNC:5195Mapping file id9956 NCBI fileEvidenceTAS
GeneHS3ST3A1AuthorityHGNC:5196Mapping file id9955 NCBI fileEvidenceTAS
GeneHS3ST3B1AuthorityHGNC:5198Mapping file id9953 NCBI fileEvidenceTAS
GeneHS3ST4AuthorityHGNC:5200Mapping file id9951 NCBI fileEvidenceTAS
GeneHS3ST5AuthorityHGNC:19419Mapping file id222537 NCBI fileEvidenceTAS
GeneHS3ST6AuthorityHGNC:14178Mapping file id64711 NCBI fileEvidenceTAS
GeneHS6ST1AuthorityHGNC:5201Mapping file id9394 NCBI fileEvidenceTAS
GeneHS6ST2AuthorityHGNC:19133Mapping file id90161 NCBI fileEvidenceTAS
GeneHS6ST3AuthorityHGNC:19134Mapping file id266722 NCBI fileEvidenceTAS
GeneHSPG2AuthorityHGNC:5273Mapping file id3339 NCBI fileEvidenceIEA, TAS
GeneHYAL1AuthorityHGNC:5320Mapping file id3373 NCBI fileEvidenceTAS
GeneHYAL2AuthorityHGNC:5321Mapping file id8692 NCBI fileEvidenceTAS
GeneHYAL3AuthorityHGNC:5322Mapping file id8372 NCBI fileEvidenceTAS
GeneHYAL4AuthorityHGNC:5323Mapping file id23553 NCBI fileEvidenceTAS
GeneIDSAuthorityHGNC:5389Mapping file id3423 NCBI fileEvidenceTAS
GeneIDUAAuthorityHGNC:5391Mapping file id3425 NCBI fileEvidenceTAS
GeneKERAAuthorityHGNC:6309Mapping file id11081 NCBI fileEvidenceTAS
GeneKHKAuthorityHGNC:6315Mapping file id3795 NCBI fileEvidenceTAS
GeneLALBAAuthorityHGNC:6480Mapping file id3906 NCBI fileEvidenceTAS
GeneLUMAuthorityHGNC:6724Mapping file id4060 NCBI fileEvidenceTAS
GeneLYVE1AuthorityHGNC:14687Mapping file id10894 NCBI fileEvidenceTAS
GeneMAN2B1AuthorityHGNC:6826Mapping file id4125 NCBI fileEvidenceTAS
GeneMAN2B2AuthorityHGNC:29623Mapping file id23324 NCBI fileEvidenceTAS
GeneMAN2C1AuthorityHGNC:6827Mapping file id4123 NCBI fileEvidenceTAS
GeneMANBAAuthorityHGNC:6831Mapping file id4126 NCBI fileEvidenceTAS
GeneNAGLUAuthorityHGNC:7632Mapping file id4669 NCBI fileEvidenceTAS
GeneNCANAuthorityHGNC:2465Mapping file id1463 NCBI fileEvidenceTAS
GeneNDC1AuthorityHGNC:25525Mapping file id55706 NCBI fileEvidenceTAS
GeneNDST1AuthorityHGNC:7680Mapping file id3340 NCBI fileEvidenceTAS
GeneNDST2AuthorityHGNC:7681Mapping file id8509 NCBI fileEvidenceTAS
GeneNDST3AuthorityHGNC:7682Mapping file id9348 NCBI fileEvidenceTAS
GeneNDST4AuthorityHGNC:20779Mapping file id64579 NCBI fileEvidenceTAS
GeneNHLRC1AuthorityHGNC:21576Mapping file id378884 NCBI fileEvidenceTAS
GeneNUP107AuthorityHGNC:29914Mapping file id57122 NCBI fileEvidenceTAS
GeneNUP133AuthorityHGNC:18016Mapping file id55746 NCBI fileEvidenceTAS
GeneNUP153AuthorityHGNC:8062Mapping file id9972 NCBI fileEvidenceTAS
GeneNUP155AuthorityHGNC:8063Mapping file id9631 NCBI fileEvidenceTAS
GeneNUP160AuthorityHGNC:18017Mapping file id23279 NCBI fileEvidenceTAS
GeneNUP188AuthorityHGNC:17859Mapping file id23511 NCBI fileEvidenceTAS
GeneNUP205AuthorityHGNC:18658Mapping file id23165 NCBI fileEvidenceTAS
GeneNUP210AuthorityHGNC:30052Mapping file id23225 NCBI fileEvidenceTAS
GeneNUP214AuthorityHGNC:8064Mapping file id8021 NCBI fileEvidenceTAS
GeneNUP35AuthorityHGNC:29797Mapping file id129401 NCBI fileEvidenceTAS
GeneNUP37AuthorityHGNC:29929Mapping file id79023 NCBI fileEvidenceTAS
GeneNUP42AuthorityHGNC:17010Mapping file id11097 NCBI fileEvidenceTAS
GeneNUP43AuthorityHGNC:21182Mapping file id348995 NCBI fileEvidenceTAS
GeneNUP50AuthorityHGNC:8065Mapping file id10762 NCBI fileEvidenceTAS
GeneNUP54AuthorityHGNC:17359Mapping file id53371 NCBI fileEvidenceTAS
GeneNUP58AuthorityHGNC:20261Mapping file id9818 NCBI fileEvidenceTAS
GeneNUP62AuthorityHGNC:8066Mapping file id23636 NCBI fileEvidenceTAS
GeneNUP85AuthorityHGNC:8734Mapping file id79902 NCBI fileEvidenceTAS
GeneNUP88AuthorityHGNC:8067Mapping file id4927 NCBI fileEvidenceTAS
GeneNUP93AuthorityHGNC:28958Mapping file id9688 NCBI fileEvidenceTAS
GeneNUP98AuthorityHGNC:8068Mapping file id4928 NCBI fileEvidenceTAS
GeneOGNAuthorityHGNC:8126Mapping file id4969 NCBI fileEvidenceTAS
GeneOMDAuthorityHGNC:8134Mapping file id4958 NCBI fileEvidenceTAS

Evidence codes on this page: IEA, TAS, as the mapping file writes them; a row carrying two was written twice by the file, once under each. The mapping file id says which file placed the gene: an NCBI Gene id from NCBI2Reactome_All_Levels.txt, an Ensembl gene id from Ensembl2Reactome_All_Levels.txt. The two files can disagree about a code, so a row's codes are the one file's view. Measured by this site's build over this release on 2026-09-09: of the 138,908 human pathway-gene pairs both files place, 207 (0.149 per cent, over 47 genes) carry TAS in the Ensembl file where the NCBI rows carry IEA alone.

  • Reactome mapping files, the human rows for this pathway · Reactome release 97 · read · Reactome downloads"NCBI2Reactome_All_Levels.txt" and "Ensembl2Reactome_All_Levels.txt", Reactome, release 97, https://reactome.org/download-data/ (date of access 2026-09-09). Data CC0; attribution encouraged.

03The hierarchy

Parents and children in this release's hierarchy

Reactome's hierarchy is a graph rather than a tree: a pathway can sit under more than one parent, and the gene counts are each pathway's own placements at every level under it, so a parent's count is not the sum of its children's.

  • Reactome, the human pathway list and hierarchy relationship file · Reactome release 97 · read · Reactome downloads"ReactomePathways.txt" and "ReactomePathwaysRelation.txt", Reactome, release 97, https://reactome.org/download-data/ (date of access 2026-09-09). Data CC0; attribution encouraged.