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Pathway Human Homo sapiens

Metabolism of carbohydrates and carbohydrate derivatives

R-HSA-71387 in Reactome release 97: under Metabolism, with 300 genes placed in it by the mapping files and 10 child pathways in the hierarchy.

The same number in the other species

Reactome writes the mouse and rat events it infers from a human pathway under the human number with the species token. A door opens only where that species' own list in this release holds the id: R-MMU-71387 (mouse), R-RNO-71387 (rat). Whether the event was inferred from this one is what the record says.

01The record

Reactome's own record of this pathway

What this tells you

The pathway list, the hierarchy and the genes on this page are read from the files Reactome publishes for Reactome release 97, built into this site on 2026-09-09: the pathway list, the hierarchy relationship file and the two gene mapping files. The record card is the one live read, Reactome's own record of this pathway.

Reactome's download page describes the mapping files: Mapping files link the source database identifier to the lowest level pathway diagram or subset of the pathway, all levels of the pathway hierarchy or database identifier to all reactions. [R13] The gene list here is the all-levels mapping of NCBI Gene ids, filled from the all-levels mapping of Ensembl ids where the NCBI file has no row for a gene; each row names which file it came from by the shape of its source id. Each row carries the evidence codes the file writes for it, as written and unranked, and both where the file writes both; no page of Reactome's documentation the survey read defines the codes, so this page does not expand them. A gene id the identity files do not name is kept as the source's own id with no door rather than turned into a symbol.

On citing what a search finds, Reactome says: It should be remembered that while we strive to contain the most current and accurate data, Reactome should not be used in citations where other primary sources of information are available. [R12] The record card prints the literature Reactome attaches to a curated pathway for that reason. The data are public domain: All data in the Reactome database and files derived from that data are licensed under the Creative Commons Public Domain Dedication (CC0). User may copy, modify, and distribute these data, even for commercial purposes, without asking for permission. Attribution is encouraged but not required. [R10] The pathway illustrations are licensed apart, under CC BY 4.0, and none is shown here.

A gene on this list is one Reactome places in this pathway in this release, and that is all the row says: it does not say the gene is expressed in a tissue or associated with a disease, which are the other two explorers' questions, read from other sources. Reactome's papers of record are [R01] [R02].

  1. [R01] Ragueneau E, Gong C, Sinquin P, Sevilla C, Beavers D, Grentner A, et al. (2026). The Reactome Knowledgebase 2026. Nucleic Acids Research 54:D673-D681. PMID 41251150, doi 10.1093/nar/gkaf1223.
  2. [R02] Milacic M, Beavers D, Conley P, Gong C, Gillespie M, Griss J, et al. (2024). The Reactome Pathway Knowledgebase 2024. Nucleic Acids Research 52:D672-D678. PMID 37941124, doi 10.1093/nar/gkad1025.
  3. [R10] Reactome, reactome.org. License Agreement. https://reactome.org/license, read 2026-09-09.
  4. [R12] Reactome, reactome.org. Citing us. https://reactome.org/cite, read 2026-09-09.
  5. [R13] Reactome, reactome.org. Download. https://reactome.org/download-data, read 2026-09-09.
Reading this pathway's record from Reactome (the pathway record).Still reading. A first read of a pathway can take a while; this page waits up to 35 seconds for it, and its scripts then bring in the panel, or a line saying what did not arrive.

02The genes

Genes Reactome places in this human pathway

The mapping files place 300 genes in this human pathway; showing 201 to 300, in pages of 100, sorted by symbol for reading. The order carries no ranking.

Genes Reactome places in this human pathway, page 3 of 3
GenePAPSS1AuthorityHGNC:8603Mapping file id9061 NCBI fileEvidenceTAS
GenePAPSS2AuthorityHGNC:8604Mapping file id9060 NCBI fileEvidenceTAS
GenePCAuthorityHGNC:8636Mapping file id5091 NCBI fileEvidenceTAS
GenePCK1AuthorityHGNC:8724Mapping file id5105 NCBI fileEvidenceTAS
GenePCK2AuthorityHGNC:8725Mapping file id5106 NCBI fileEvidenceTAS
GenePFKFB1AuthorityHGNC:8872Mapping file id5207 NCBI fileEvidenceIEA, TAS
GenePFKFB2AuthorityHGNC:8873Mapping file id5208 NCBI fileEvidenceTAS
GenePFKFB3AuthorityHGNC:8874Mapping file id5209 NCBI fileEvidenceTAS
GenePFKFB4AuthorityHGNC:8875Mapping file id5210 NCBI fileEvidenceTAS
GenePFKLAuthorityHGNC:8876Mapping file id5211 NCBI fileEvidenceTAS
GenePFKMAuthorityHGNC:8877Mapping file id5213 NCBI fileEvidenceTAS
GenePFKPAuthorityHGNC:8878Mapping file id5214 NCBI fileEvidenceTAS
GenePGAM1AuthorityHGNC:8888Mapping file id5223 NCBI fileEvidenceTAS
GenePGAM2AuthorityHGNC:8889Mapping file id5224 NCBI fileEvidenceTAS
GenePGDAuthorityHGNC:8891Mapping file id5226 NCBI fileEvidenceTAS
GenePGK1AuthorityHGNC:8896Mapping file id5230 NCBI fileEvidenceTAS
GenePGK2AuthorityHGNC:8898Mapping file id5232 NCBI fileEvidenceTAS
GenePGLSAuthorityHGNC:8903Mapping file id25796 NCBI fileEvidenceTAS
GenePGM1AuthorityHGNC:8905Mapping file id5236 NCBI fileEvidenceTAS
GenePGM2AuthorityHGNC:8906Mapping file id55276 NCBI fileEvidenceTAS
GenePGM2L1AuthorityHGNC:20898Mapping file id283209 NCBI fileEvidenceTAS
GenePHKA1AuthorityHGNC:8925Mapping file id5255 NCBI fileEvidenceIEA, TAS
GenePHKA2AuthorityHGNC:8926Mapping file id5256 NCBI fileEvidenceTAS
GenePHKBAuthorityHGNC:8927Mapping file id5257 NCBI fileEvidenceIEA, TAS
GenePHKG1AuthorityHGNC:8930Mapping file id5260 NCBI fileEvidenceIEA, TAS
GenePHKG2AuthorityHGNC:8931Mapping file id5261 NCBI fileEvidenceTAS
GenePKLRAuthorityHGNC:9020Mapping file id5313 NCBI fileEvidenceTAS
GenePKMAuthorityHGNC:9021Mapping file id5315 NCBI fileEvidenceTAS
GenePOM121AuthorityHGNC:19702Mapping file id9883 NCBI fileEvidenceTAS
GenePOM121CAuthorityHGNC:34005Mapping file idENSG00000272391 Ensembl fileEvidenceTAS
GenePPP1R3CAuthorityHGNC:9293Mapping file id5507 NCBI fileEvidenceTAS
GenePPP2CAAuthorityHGNC:9299Mapping file id5515 NCBI fileEvidenceIEA
GenePPP2CBAuthorityHGNC:9300Mapping file id5516 NCBI fileEvidenceIEA
GenePPP2R1AAuthorityHGNC:9302Mapping file id5518 NCBI fileEvidenceIEA
GenePPP2R1BAuthorityHGNC:9303Mapping file id5519 NCBI fileEvidenceIEA
GenePPP2R5DAuthorityHGNC:9312Mapping file id5528 NCBI fileEvidenceIEA
GenePRELPAuthorityHGNC:9357Mapping file id5549 NCBI fileEvidenceTAS
GenePRKACAAuthorityHGNC:9380Mapping file id5566 NCBI fileEvidenceIEA
GenePRKACBAuthorityHGNC:9381Mapping file id5567 NCBI fileEvidenceIEA
GenePRKACGAuthorityHGNC:9382Mapping file id5568 NCBI fileEvidenceIEA
GenePRPS1AuthorityHGNC:9462Mapping file id5631 NCBI fileEvidenceTAS
GenePRPS1L1AuthorityHGNC:9463Mapping file id221823 NCBI fileEvidenceTAS
GenePRPS2AuthorityHGNC:9465Mapping file id5634 NCBI fileEvidenceTAS
GenePXYLP1AuthorityHGNC:26303Mapping file id92370 NCBI fileEvidenceTAS
GenePYGBAuthorityHGNC:9723Mapping file id5834 NCBI fileEvidenceIEA
GenePYGLAuthorityHGNC:9725Mapping file id5836 NCBI fileEvidenceTAS
GenePYGMAuthorityHGNC:9726Mapping file id5837 NCBI fileEvidenceIEA, TAS
GeneRAE1AuthorityHGNC:9828Mapping file id8480 NCBI fileEvidenceTAS
GeneRANBP2AuthorityHGNC:9848Mapping file id5903 NCBI fileEvidenceTAS
GeneRBKSAuthorityHGNC:30325Mapping file id64080 NCBI fileEvidenceTAS
GeneRHCEAuthorityHGNC:10008Mapping file id6006 NCBI fileEvidenceTAS
GeneRHDAuthorityHGNC:10009Mapping file id6007 NCBI fileEvidenceTAS
GeneRPEAuthorityHGNC:10293Mapping file id6120 NCBI fileEvidenceTAS
GeneRPEL1AuthorityHGNC:45241Mapping file id729020 NCBI fileEvidenceTAS
GeneRPIAAuthorityHGNC:10297Mapping file id22934 NCBI fileEvidenceTAS
GeneRPS27AAuthorityHGNC:10417Mapping file id6233 NCBI fileEvidenceTAS
GeneSDC1AuthorityHGNC:10658Mapping file id6382 NCBI fileEvidenceIEA, TAS
GeneSDC2AuthorityHGNC:10659Mapping file id6383 NCBI fileEvidenceIEA, TAS
GeneSDC3AuthorityHGNC:10660Mapping file id9672 NCBI fileEvidenceIEA, TAS
GeneSDC4AuthorityHGNC:10661Mapping file id6385 NCBI fileEvidenceIEA, TAS
GeneSEC13AuthorityHGNC:10697Mapping file id6396 NCBI fileEvidenceTAS
GeneSEH1LAuthorityHGNC:30379Mapping file id81929 NCBI fileEvidenceTAS
GeneSGSHAuthorityHGNC:10818Mapping file id6448 NCBI fileEvidenceTAS
GeneSHPKAuthorityHGNC:1492Mapping file id23729 NCBI fileEvidenceTAS
GeneSLC17A5AuthorityHGNC:10933Mapping file id26503 NCBI fileEvidenceTAS
GeneSLC26A1AuthorityHGNC:10993Mapping file id10861 NCBI fileEvidenceTAS
GeneSLC26A11AuthorityHGNC:14471Mapping file id284129 NCBI fileEvidenceTAS
GeneSLC26A2AuthorityHGNC:10994Mapping file id1836 NCBI fileEvidenceTAS
GeneSLC2A1AuthorityHGNC:11005Mapping file id6513 NCBI fileEvidenceTAS
GeneSLC35B2AuthorityHGNC:16872Mapping file id347734 NCBI fileEvidenceTAS
GeneSLC35B3AuthorityHGNC:21601Mapping file id51000 NCBI fileEvidenceTAS
GeneSLC35D2AuthorityHGNC:20799Mapping file id11046 NCBI fileEvidenceTAS
GeneSLC37A1AuthorityHGNC:11024Mapping file id54020 NCBI fileEvidenceTAS
GeneSLC37A2AuthorityHGNC:20644Mapping file id219855 NCBI fileEvidenceTAS
GeneSLC37A4AuthorityHGNC:4061Mapping file id2542 NCBI fileEvidenceTAS
GeneSLC9A1AuthorityHGNC:11071Mapping file id6548 NCBI fileEvidenceTAS
GeneSORDAuthorityHGNC:11184Mapping file id6652 NCBI fileEvidenceTAS
GeneSPAM1AuthorityHGNC:11217Mapping file id6677 NCBI fileEvidenceTAS
GeneST3GAL1AuthorityHGNC:10862Mapping file id6482 NCBI fileEvidenceTAS
GeneST3GAL2AuthorityHGNC:10863Mapping file id6483 NCBI fileEvidenceTAS
GeneST3GAL3AuthorityHGNC:10866Mapping file id6487 NCBI fileEvidenceTAS
GeneST3GAL4AuthorityHGNC:10864Mapping file id6484 NCBI fileEvidenceTAS
GeneST3GAL6AuthorityHGNC:18080Mapping file id10402 NCBI fileEvidenceTAS
GeneST6GALNAC6AuthorityHGNC:23364Mapping file id30815 NCBI fileEvidenceTAS
GeneSTAB2AuthorityHGNC:18629Mapping file id55576 NCBI fileEvidenceTAS
GeneTALDO1AuthorityHGNC:11559Mapping file id6888 NCBI fileEvidenceTAS
GeneTKFCAuthorityHGNC:24552Mapping file id26007 NCBI fileEvidenceTAS
GeneTKTAuthorityHGNC:11834Mapping file id7086 NCBI fileEvidenceTAS
GeneTPI1AuthorityHGNC:12009Mapping file id7167 NCBI fileEvidenceTAS
GeneTPRAuthorityHGNC:12017Mapping file id7175 NCBI fileEvidenceTAS
GeneUBA52AuthorityHGNC:12458Mapping file id7311 NCBI fileEvidenceTAS
GeneUBBAuthorityHGNC:12463Mapping file id7314 NCBI fileEvidenceTAS
GeneUBCAuthorityHGNC:12468Mapping file id7316 NCBI fileEvidenceTAS
GeneUGP2AuthorityHGNC:12527Mapping file id7360 NCBI fileEvidenceTAS
GeneUSTAuthorityHGNC:17223Mapping file id10090 NCBI fileEvidenceTAS
GeneUXS1AuthorityHGNC:17729Mapping file id80146 NCBI fileEvidenceTAS
GeneVCANAuthorityHGNC:2464Mapping file id1462 NCBI fileEvidenceTAS
GeneXYLBAuthorityHGNC:12839Mapping file id9942 NCBI fileEvidenceTAS
GeneXYLT1AuthorityHGNC:15516Mapping file id64131 NCBI fileEvidenceTAS
GeneXYLT2AuthorityHGNC:15517Mapping file id64132 NCBI fileEvidenceTAS

Evidence codes on this page: IEA, TAS, as the mapping file writes them; a row carrying two was written twice by the file, once under each. The mapping file id says which file placed the gene: an NCBI Gene id from NCBI2Reactome_All_Levels.txt, an Ensembl gene id from Ensembl2Reactome_All_Levels.txt. The two files can disagree about a code, so a row's codes are the one file's view. Measured by this site's build over this release on 2026-09-09: of the 138,908 human pathway-gene pairs both files place, 207 (0.149 per cent, over 47 genes) carry TAS in the Ensembl file where the NCBI rows carry IEA alone.

  • Reactome mapping files, the human rows for this pathway · Reactome release 97 · read · Reactome downloads"NCBI2Reactome_All_Levels.txt" and "Ensembl2Reactome_All_Levels.txt", Reactome, release 97, https://reactome.org/download-data/ (date of access 2026-09-09). Data CC0; attribution encouraged.

03The hierarchy

Parents and children in this release's hierarchy

Reactome's hierarchy is a graph rather than a tree: a pathway can sit under more than one parent, and the gene counts are each pathway's own placements at every level under it, so a parent's count is not the sum of its children's.

  • Reactome, the human pathway list and hierarchy relationship file · Reactome release 97 · read · Reactome downloads"ReactomePathways.txt" and "ReactomePathwaysRelation.txt", Reactome, release 97, https://reactome.org/download-data/ (date of access 2026-09-09). Data CC0; attribution encouraged.