Pathway Human Homo sapiens
Metabolism of carbohydrates and carbohydrate derivatives
R-HSA-71387 in Reactome release 97: under Metabolism, with 300 genes placed in it by the mapping files and 10 child pathways in the hierarchy.
The same number in the other species
Reactome writes the mouse and rat events it infers from a human pathway under the human number with the species token. A door opens only where that species' own list in this release holds the id: R-MMU-71387 (mouse), R-RNO-71387 (rat). Whether the event was inferred from this one is what the record says.
01The record
Reactome's own record of this pathway
What this tells you
The pathway list, the hierarchy and the genes on this page are read from the files Reactome publishes for Reactome release 97, built into this site on 2026-09-09: the pathway list, the hierarchy relationship file and the two gene mapping files. The record card is the one live read, Reactome's own record of this pathway.
Reactome's download page describes the mapping files: Mapping files link the source database identifier to the lowest level pathway diagram or subset of the pathway, all levels of the pathway hierarchy or database identifier to all reactions.
[R13] The gene list here is the all-levels mapping of NCBI Gene ids, filled from the all-levels mapping of Ensembl ids where the NCBI file has no row for a gene; each row names which file it came from by the shape of its source id. Each row carries the evidence codes the file writes for it, as written and unranked, and both where the file writes both; no page of Reactome's documentation the survey read defines the codes, so this page does not expand them. A gene id the identity files do not name is kept as the source's own id with no door rather than turned into a symbol.
On citing what a search finds, Reactome says: It should be remembered that while we strive to contain the most current and accurate data, Reactome should not be used in citations where other primary sources of information are available.
[R12] The record card prints the literature Reactome attaches to a curated pathway for that reason. The data are public domain: All data in the Reactome database and files derived from that data are licensed under the Creative Commons Public Domain Dedication (CC0). User may copy, modify, and distribute these data, even for commercial purposes, without asking for permission. Attribution is encouraged but not required.
[R10] The pathway illustrations are licensed apart, under CC BY 4.0, and none is shown here.
A gene on this list is one Reactome places in this pathway in this release, and that is all the row says: it does not say the gene is expressed in a tissue or associated with a disease, which are the other two explorers' questions, read from other sources. Reactome's papers of record are [R01] [R02].
- [R01] Ragueneau E, Gong C, Sinquin P, Sevilla C, Beavers D, Grentner A, et al. (2026). The Reactome Knowledgebase 2026. Nucleic Acids Research 54:D673-D681. PMID 41251150, doi 10.1093/nar/gkaf1223.
- [R02] Milacic M, Beavers D, Conley P, Gong C, Gillespie M, Griss J, et al. (2024). The Reactome Pathway Knowledgebase 2024. Nucleic Acids Research 52:D672-D678. PMID 37941124, doi 10.1093/nar/gkad1025.
- [R10] Reactome, reactome.org. License Agreement. https://reactome.org/license, read 2026-09-09.
- [R12] Reactome, reactome.org. Citing us. https://reactome.org/cite, read 2026-09-09.
- [R13] Reactome, reactome.org. Download. https://reactome.org/download-data, read 2026-09-09.
02The genes
Genes Reactome places in this human pathway
The mapping files place 300 genes in this human pathway; showing 201 to 300, in pages of 100, sorted by symbol for reading. The order carries no ranking.
| Gene | Authority id | Mapping file id | Evidence codes |
|---|---|---|---|
| GenePAPSS1 | AuthorityHGNC:8603 | Mapping file id9061 NCBI file | EvidenceTAS |
| GenePAPSS2 | AuthorityHGNC:8604 | Mapping file id9060 NCBI file | EvidenceTAS |
| GenePC | AuthorityHGNC:8636 | Mapping file id5091 NCBI file | EvidenceTAS |
| GenePCK1 | AuthorityHGNC:8724 | Mapping file id5105 NCBI file | EvidenceTAS |
| GenePCK2 | AuthorityHGNC:8725 | Mapping file id5106 NCBI file | EvidenceTAS |
| GenePFKFB1 | AuthorityHGNC:8872 | Mapping file id5207 NCBI file | EvidenceIEA, TAS |
| GenePFKFB2 | AuthorityHGNC:8873 | Mapping file id5208 NCBI file | EvidenceTAS |
| GenePFKFB3 | AuthorityHGNC:8874 | Mapping file id5209 NCBI file | EvidenceTAS |
| GenePFKFB4 | AuthorityHGNC:8875 | Mapping file id5210 NCBI file | EvidenceTAS |
| GenePFKL | AuthorityHGNC:8876 | Mapping file id5211 NCBI file | EvidenceTAS |
| GenePFKM | AuthorityHGNC:8877 | Mapping file id5213 NCBI file | EvidenceTAS |
| GenePFKP | AuthorityHGNC:8878 | Mapping file id5214 NCBI file | EvidenceTAS |
| GenePGAM1 | AuthorityHGNC:8888 | Mapping file id5223 NCBI file | EvidenceTAS |
| GenePGAM2 | AuthorityHGNC:8889 | Mapping file id5224 NCBI file | EvidenceTAS |
| GenePGD | AuthorityHGNC:8891 | Mapping file id5226 NCBI file | EvidenceTAS |
| GenePGK1 | AuthorityHGNC:8896 | Mapping file id5230 NCBI file | EvidenceTAS |
| GenePGK2 | AuthorityHGNC:8898 | Mapping file id5232 NCBI file | EvidenceTAS |
| GenePGLS | AuthorityHGNC:8903 | Mapping file id25796 NCBI file | EvidenceTAS |
| GenePGM1 | AuthorityHGNC:8905 | Mapping file id5236 NCBI file | EvidenceTAS |
| GenePGM2 | AuthorityHGNC:8906 | Mapping file id55276 NCBI file | EvidenceTAS |
| GenePGM2L1 | AuthorityHGNC:20898 | Mapping file id283209 NCBI file | EvidenceTAS |
| GenePHKA1 | AuthorityHGNC:8925 | Mapping file id5255 NCBI file | EvidenceIEA, TAS |
| GenePHKA2 | AuthorityHGNC:8926 | Mapping file id5256 NCBI file | EvidenceTAS |
| GenePHKB | AuthorityHGNC:8927 | Mapping file id5257 NCBI file | EvidenceIEA, TAS |
| GenePHKG1 | AuthorityHGNC:8930 | Mapping file id5260 NCBI file | EvidenceIEA, TAS |
| GenePHKG2 | AuthorityHGNC:8931 | Mapping file id5261 NCBI file | EvidenceTAS |
| GenePKLR | AuthorityHGNC:9020 | Mapping file id5313 NCBI file | EvidenceTAS |
| GenePKM | AuthorityHGNC:9021 | Mapping file id5315 NCBI file | EvidenceTAS |
| GenePOM121 | AuthorityHGNC:19702 | Mapping file id9883 NCBI file | EvidenceTAS |
| GenePOM121C | AuthorityHGNC:34005 | Mapping file idENSG00000272391 Ensembl file | EvidenceTAS |
| GenePPP1R3C | AuthorityHGNC:9293 | Mapping file id5507 NCBI file | EvidenceTAS |
| GenePPP2CA | AuthorityHGNC:9299 | Mapping file id5515 NCBI file | EvidenceIEA |
| GenePPP2CB | AuthorityHGNC:9300 | Mapping file id5516 NCBI file | EvidenceIEA |
| GenePPP2R1A | AuthorityHGNC:9302 | Mapping file id5518 NCBI file | EvidenceIEA |
| GenePPP2R1B | AuthorityHGNC:9303 | Mapping file id5519 NCBI file | EvidenceIEA |
| GenePPP2R5D | AuthorityHGNC:9312 | Mapping file id5528 NCBI file | EvidenceIEA |
| GenePRELP | AuthorityHGNC:9357 | Mapping file id5549 NCBI file | EvidenceTAS |
| GenePRKACA | AuthorityHGNC:9380 | Mapping file id5566 NCBI file | EvidenceIEA |
| GenePRKACB | AuthorityHGNC:9381 | Mapping file id5567 NCBI file | EvidenceIEA |
| GenePRKACG | AuthorityHGNC:9382 | Mapping file id5568 NCBI file | EvidenceIEA |
| GenePRPS1 | AuthorityHGNC:9462 | Mapping file id5631 NCBI file | EvidenceTAS |
| GenePRPS1L1 | AuthorityHGNC:9463 | Mapping file id221823 NCBI file | EvidenceTAS |
| GenePRPS2 | AuthorityHGNC:9465 | Mapping file id5634 NCBI file | EvidenceTAS |
| GenePXYLP1 | AuthorityHGNC:26303 | Mapping file id92370 NCBI file | EvidenceTAS |
| GenePYGB | AuthorityHGNC:9723 | Mapping file id5834 NCBI file | EvidenceIEA |
| GenePYGL | AuthorityHGNC:9725 | Mapping file id5836 NCBI file | EvidenceTAS |
| GenePYGM | AuthorityHGNC:9726 | Mapping file id5837 NCBI file | EvidenceIEA, TAS |
| GeneRAE1 | AuthorityHGNC:9828 | Mapping file id8480 NCBI file | EvidenceTAS |
| GeneRANBP2 | AuthorityHGNC:9848 | Mapping file id5903 NCBI file | EvidenceTAS |
| GeneRBKS | AuthorityHGNC:30325 | Mapping file id64080 NCBI file | EvidenceTAS |
| GeneRHCE | AuthorityHGNC:10008 | Mapping file id6006 NCBI file | EvidenceTAS |
| GeneRHD | AuthorityHGNC:10009 | Mapping file id6007 NCBI file | EvidenceTAS |
| GeneRPE | AuthorityHGNC:10293 | Mapping file id6120 NCBI file | EvidenceTAS |
| GeneRPEL1 | AuthorityHGNC:45241 | Mapping file id729020 NCBI file | EvidenceTAS |
| GeneRPIA | AuthorityHGNC:10297 | Mapping file id22934 NCBI file | EvidenceTAS |
| GeneRPS27A | AuthorityHGNC:10417 | Mapping file id6233 NCBI file | EvidenceTAS |
| GeneSDC1 | AuthorityHGNC:10658 | Mapping file id6382 NCBI file | EvidenceIEA, TAS |
| GeneSDC2 | AuthorityHGNC:10659 | Mapping file id6383 NCBI file | EvidenceIEA, TAS |
| GeneSDC3 | AuthorityHGNC:10660 | Mapping file id9672 NCBI file | EvidenceIEA, TAS |
| GeneSDC4 | AuthorityHGNC:10661 | Mapping file id6385 NCBI file | EvidenceIEA, TAS |
| GeneSEC13 | AuthorityHGNC:10697 | Mapping file id6396 NCBI file | EvidenceTAS |
| GeneSEH1L | AuthorityHGNC:30379 | Mapping file id81929 NCBI file | EvidenceTAS |
| GeneSGSH | AuthorityHGNC:10818 | Mapping file id6448 NCBI file | EvidenceTAS |
| GeneSHPK | AuthorityHGNC:1492 | Mapping file id23729 NCBI file | EvidenceTAS |
| GeneSLC17A5 | AuthorityHGNC:10933 | Mapping file id26503 NCBI file | EvidenceTAS |
| GeneSLC26A1 | AuthorityHGNC:10993 | Mapping file id10861 NCBI file | EvidenceTAS |
| GeneSLC26A11 | AuthorityHGNC:14471 | Mapping file id284129 NCBI file | EvidenceTAS |
| GeneSLC26A2 | AuthorityHGNC:10994 | Mapping file id1836 NCBI file | EvidenceTAS |
| GeneSLC2A1 | AuthorityHGNC:11005 | Mapping file id6513 NCBI file | EvidenceTAS |
| GeneSLC35B2 | AuthorityHGNC:16872 | Mapping file id347734 NCBI file | EvidenceTAS |
| GeneSLC35B3 | AuthorityHGNC:21601 | Mapping file id51000 NCBI file | EvidenceTAS |
| GeneSLC35D2 | AuthorityHGNC:20799 | Mapping file id11046 NCBI file | EvidenceTAS |
| GeneSLC37A1 | AuthorityHGNC:11024 | Mapping file id54020 NCBI file | EvidenceTAS |
| GeneSLC37A2 | AuthorityHGNC:20644 | Mapping file id219855 NCBI file | EvidenceTAS |
| GeneSLC37A4 | AuthorityHGNC:4061 | Mapping file id2542 NCBI file | EvidenceTAS |
| GeneSLC9A1 | AuthorityHGNC:11071 | Mapping file id6548 NCBI file | EvidenceTAS |
| GeneSORD | AuthorityHGNC:11184 | Mapping file id6652 NCBI file | EvidenceTAS |
| GeneSPAM1 | AuthorityHGNC:11217 | Mapping file id6677 NCBI file | EvidenceTAS |
| GeneST3GAL1 | AuthorityHGNC:10862 | Mapping file id6482 NCBI file | EvidenceTAS |
| GeneST3GAL2 | AuthorityHGNC:10863 | Mapping file id6483 NCBI file | EvidenceTAS |
| GeneST3GAL3 | AuthorityHGNC:10866 | Mapping file id6487 NCBI file | EvidenceTAS |
| GeneST3GAL4 | AuthorityHGNC:10864 | Mapping file id6484 NCBI file | EvidenceTAS |
| GeneST3GAL6 | AuthorityHGNC:18080 | Mapping file id10402 NCBI file | EvidenceTAS |
| GeneST6GALNAC6 | AuthorityHGNC:23364 | Mapping file id30815 NCBI file | EvidenceTAS |
| GeneSTAB2 | AuthorityHGNC:18629 | Mapping file id55576 NCBI file | EvidenceTAS |
| GeneTALDO1 | AuthorityHGNC:11559 | Mapping file id6888 NCBI file | EvidenceTAS |
| GeneTKFC | AuthorityHGNC:24552 | Mapping file id26007 NCBI file | EvidenceTAS |
| GeneTKT | AuthorityHGNC:11834 | Mapping file id7086 NCBI file | EvidenceTAS |
| GeneTPI1 | AuthorityHGNC:12009 | Mapping file id7167 NCBI file | EvidenceTAS |
| GeneTPR | AuthorityHGNC:12017 | Mapping file id7175 NCBI file | EvidenceTAS |
| GeneUBA52 | AuthorityHGNC:12458 | Mapping file id7311 NCBI file | EvidenceTAS |
| GeneUBB | AuthorityHGNC:12463 | Mapping file id7314 NCBI file | EvidenceTAS |
| GeneUBC | AuthorityHGNC:12468 | Mapping file id7316 NCBI file | EvidenceTAS |
| GeneUGP2 | AuthorityHGNC:12527 | Mapping file id7360 NCBI file | EvidenceTAS |
| GeneUST | AuthorityHGNC:17223 | Mapping file id10090 NCBI file | EvidenceTAS |
| GeneUXS1 | AuthorityHGNC:17729 | Mapping file id80146 NCBI file | EvidenceTAS |
| GeneVCAN | AuthorityHGNC:2464 | Mapping file id1462 NCBI file | EvidenceTAS |
| GeneXYLB | AuthorityHGNC:12839 | Mapping file id9942 NCBI file | EvidenceTAS |
| GeneXYLT1 | AuthorityHGNC:15516 | Mapping file id64131 NCBI file | EvidenceTAS |
| GeneXYLT2 | AuthorityHGNC:15517 | Mapping file id64132 NCBI file | EvidenceTAS |
Evidence codes on this page: IEA, TAS, as the mapping file writes them; a row carrying two was written twice by the file, once under each. The mapping file id says which file placed the gene: an NCBI Gene id from NCBI2Reactome_All_Levels.txt, an Ensembl gene id from Ensembl2Reactome_All_Levels.txt. The two files can disagree about a code, so a row's codes are the one file's view. Measured by this site's build over this release on 2026-09-09: of the 138,908 human pathway-gene pairs both files place, 207 (0.149 per cent, over 47 genes) carry TAS in the Ensembl file where the NCBI rows carry IEA alone.
- Reactome mapping files, the human rows for this pathway · Reactome release 97 · read · Reactome downloads"NCBI2Reactome_All_Levels.txt" and "Ensembl2Reactome_All_Levels.txt", Reactome, release 97, https://reactome.org/download-data/ (date of access 2026-09-09). Data CC0; attribution encouraged.
03The hierarchy
Parents and children in this release's hierarchy
Children
- Blood group systems biosynthesisR-HSA-903365820 genes
- Formation of xylulose-5-phosphateR-HSA-56612705 genes
- Fructose metabolismR-HSA-56520847 genes
- Galactose catabolismR-HSA-703706 genes
- Glucose metabolismR-HSA-7032684 genes
- Glycogen metabolismR-HSA-898249128 genes
- Glycosaminoglycan metabolismR-HSA-1630316136 genes
- Lactose synthesisR-HSA-56538903 genes
- Lysosomal oligosaccharide catabolismR-HSA-88533834 genes
- Pentose phosphate pathwayR-HSA-7133615 genes
Reactome's hierarchy is a graph rather than a tree: a pathway can sit under more than one parent, and the gene counts are each pathway's own placements at every level under it, so a parent's count is not the sum of its children's.
- Reactome, the human pathway list and hierarchy relationship file · Reactome release 97 · read · Reactome downloads"ReactomePathways.txt" and "ReactomePathwaysRelation.txt", Reactome, release 97, https://reactome.org/download-data/ (date of access 2026-09-09). Data CC0; attribution encouraged.