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Pathway Human Homo sapiens

Parasitic Infection Pathways

R-HSA-9824443 in Reactome release 97: under Infectious disease, with 223 genes placed in it by the mapping files and 1 child pathway in the hierarchy.

The same number in the other species

Reactome writes the mouse and rat events it infers from a human pathway under the human number with the species token. A door opens only where that species' own list in this release holds the id; neither of the other two lists holds it. Whether the event was inferred from this one is what the record says.

01The record

Reactome's own record of this pathway

What this tells you

The pathway list, the hierarchy and the genes on this page are read from the files Reactome publishes for Reactome release 97, built into this site on 2026-09-09: the pathway list, the hierarchy relationship file and the two gene mapping files. The record card is the one live read, Reactome's own record of this pathway.

Reactome's download page describes the mapping files: Mapping files link the source database identifier to the lowest level pathway diagram or subset of the pathway, all levels of the pathway hierarchy or database identifier to all reactions. [R13] The gene list here is the all-levels mapping of NCBI Gene ids, filled from the all-levels mapping of Ensembl ids where the NCBI file has no row for a gene; each row names which file it came from by the shape of its source id. Each row carries the evidence codes the file writes for it, as written and unranked, and both where the file writes both; no page of Reactome's documentation the survey read defines the codes, so this page does not expand them. A gene id the identity files do not name is kept as the source's own id with no door rather than turned into a symbol.

On citing what a search finds, Reactome says: It should be remembered that while we strive to contain the most current and accurate data, Reactome should not be used in citations where other primary sources of information are available. [R12] The record card prints the literature Reactome attaches to a curated pathway for that reason. The data are public domain: All data in the Reactome database and files derived from that data are licensed under the Creative Commons Public Domain Dedication (CC0). User may copy, modify, and distribute these data, even for commercial purposes, without asking for permission. Attribution is encouraged but not required. [R10] The pathway illustrations are licensed apart, under CC BY 4.0, and none is shown here.

A gene on this list is one Reactome places in this pathway in this release, and that is all the row says: it does not say the gene is expressed in a tissue or associated with a disease, which are the other two explorers' questions, read from other sources. Reactome's papers of record are [R01] [R02].

  1. [R01] Ragueneau E, Gong C, Sinquin P, Sevilla C, Beavers D, Grentner A, et al. (2026). The Reactome Knowledgebase 2026. Nucleic Acids Research 54:D673-D681. PMID 41251150, doi 10.1093/nar/gkaf1223.
  2. [R02] Milacic M, Beavers D, Conley P, Gong C, Gillespie M, Griss J, et al. (2024). The Reactome Pathway Knowledgebase 2024. Nucleic Acids Research 52:D672-D678. PMID 37941124, doi 10.1093/nar/gkad1025.
  3. [R10] Reactome, reactome.org. License Agreement. https://reactome.org/license, read 2026-09-09.
  4. [R12] Reactome, reactome.org. Citing us. https://reactome.org/cite, read 2026-09-09.
  5. [R13] Reactome, reactome.org. Download. https://reactome.org/download-data, read 2026-09-09.
Reading this pathway's record from Reactome (the pathway record).Still reading. A first read of a pathway can take a while; this page waits up to 35 seconds for it, and its scripts then bring in the panel, or a line saying what did not arrive.

02The genes

Genes Reactome places in this human pathway

The mapping files place 223 genes in this human pathway; showing 1 to 100, in pages of 100, sorted by symbol for reading. The order carries no ranking.

Genes Reactome places in this human pathway, page 1 of 3
GeneABI1AuthorityHGNC:11320Mapping file id10006 NCBI fileEvidenceIEA, TAS
GeneABI2AuthorityHGNC:24011Mapping file id10152 NCBI fileEvidenceIEA, TAS
GeneABL1AuthorityHGNC:76Mapping file id25 NCBI fileEvidenceTAS
GeneACTBAuthorityHGNC:132Mapping file id60 NCBI fileEvidenceIEA, TAS
GeneACTG1AuthorityHGNC:144Mapping file id71 NCBI fileEvidenceIEA, TAS
GeneACTR2AuthorityHGNC:169Mapping file id10097 NCBI fileEvidenceIEA, TAS
GeneACTR3AuthorityHGNC:170Mapping file id10096 NCBI fileEvidenceIEA, TAS
GeneADAM17AuthorityHGNC:195Mapping file id6868 NCBI fileEvidenceTAS
GeneADCY1AuthorityHGNC:232Mapping file id107 NCBI fileEvidenceIEA, TAS
GeneADCY2AuthorityHGNC:233Mapping file id108 NCBI fileEvidenceIEA, TAS
GeneADCY3AuthorityHGNC:234Mapping file id109 NCBI fileEvidenceIEA, TAS
GeneADCY4AuthorityHGNC:235Mapping file id196883 NCBI fileEvidenceIEA, TAS
GeneADCY5AuthorityHGNC:236Mapping file id111 NCBI fileEvidenceIEA, TAS
GeneADCY6AuthorityHGNC:237Mapping file id112 NCBI fileEvidenceIEA, TAS
GeneADCY7AuthorityHGNC:238Mapping file id113 NCBI fileEvidenceIEA, TAS
GeneADCY8AuthorityHGNC:239Mapping file id114 NCBI fileEvidenceIEA, TAS
GeneADCY9AuthorityHGNC:240Mapping file id115 NCBI fileEvidenceIEA, TAS
GeneADORA2BAuthorityHGNC:264Mapping file id136 NCBI fileEvidenceTAS
GeneAHCYL1AuthorityHGNC:344Mapping file id10768 NCBI fileEvidenceIEA
GeneAPPAuthorityHGNC:620Mapping file id351 NCBI fileEvidenceTAS
GeneARPC1AAuthorityHGNC:703Mapping file id10552 NCBI fileEvidenceIEA, TAS
GeneARPC1BAuthorityHGNC:704Mapping file id10095 NCBI fileEvidenceIEA, TAS
GeneARPC2AuthorityHGNC:705Mapping file id10109 NCBI fileEvidenceIEA, TAS
GeneARPC3AuthorityHGNC:706Mapping file id10094 NCBI fileEvidenceIEA, TAS
GeneARPC4AuthorityHGNC:707Mapping file id10093 NCBI fileEvidenceIEA, TAS
GeneARPC5AuthorityHGNC:708Mapping file id10092 NCBI fileEvidenceIEA, TAS
GeneBAIAP2AuthorityHGNC:947Mapping file id10458 NCBI fileEvidenceIEA, TAS
GeneBRK1AuthorityHGNC:23057Mapping file id55845 NCBI fileEvidenceIEA, TAS
GeneBTKAuthorityHGNC:1133Mapping file id695 NCBI fileEvidenceTAS
GeneC3AuthorityHGNC:1318Mapping file id718 NCBI fileEvidenceTAS
GeneC3AR1AuthorityHGNC:1319Mapping file id719 NCBI fileEvidenceTAS
GeneCALM1AuthorityHGNC:1442Mapping file id801 NCBI fileEvidenceIEA, TAS
GeneCALM2AuthorityHGNC:1445Mapping file id805 NCBI fileEvidenceIEA, TAS
GeneCALM3AuthorityHGNC:1449Mapping file id808 NCBI fileEvidenceIEA, TAS
GeneCASP1AuthorityHGNC:1499Mapping file id834 NCBI fileEvidenceTAS
GeneCD163AuthorityHGNC:1631Mapping file id9332 NCBI fileEvidenceTAS
GeneCD247AuthorityHGNC:1677Mapping file id919 NCBI fileEvidenceTAS
GeneCD3GAuthorityHGNC:1675Mapping file id917 NCBI fileEvidenceTAS
GeneCDC42AuthorityHGNC:1736Mapping file id998 NCBI fileEvidenceIEA, TAS
GeneCREB1AuthorityHGNC:2345Mapping file id1385 NCBI fileEvidenceIEA, TAS
GeneCRKAuthorityHGNC:2362Mapping file id1398 NCBI fileEvidenceTAS
GeneCTSGAuthorityHGNC:2532Mapping file id1511 NCBI fileEvidenceTAS
GeneCYBAAuthorityHGNC:2577Mapping file id1535 NCBI fileEvidenceTAS
GeneCYFIP1AuthorityHGNC:13759Mapping file id23191 NCBI fileEvidenceIEA, TAS
GeneCYFIP2AuthorityHGNC:13760Mapping file id26999 NCBI fileEvidenceIEA, TAS
GeneCYSLTR1AuthorityHGNC:17451Mapping file id10800 NCBI fileEvidenceTAS
GeneCYSLTR2AuthorityHGNC:18274Mapping file id57105 NCBI fileEvidenceTAS
GeneDOCK1AuthorityHGNC:2987Mapping file id1793 NCBI fileEvidenceTAS
GeneDPEP1AuthorityHGNC:3002Mapping file id1800 NCBI fileEvidenceTAS
GeneDPEP2AuthorityHGNC:23028Mapping file id64174 NCBI fileEvidenceTAS
GeneDVL1AuthorityHGNC:3084Mapping file id1855 NCBI fileEvidenceIEA, TAS
GeneDVL2AuthorityHGNC:3086Mapping file id1856 NCBI fileEvidenceIEA, TAS
GeneDVL3AuthorityHGNC:3087Mapping file id1857 NCBI fileEvidenceIEA, TAS
GeneELMO1AuthorityHGNC:16286Mapping file id9844 NCBI fileEvidenceTAS
GeneELMO2AuthorityHGNC:17233Mapping file id63916 NCBI fileEvidenceTAS
GeneENTPD1AuthorityHGNC:3363Mapping file id953 NCBI fileEvidenceTAS
GeneENTPD5AuthorityHGNC:3367Mapping file id957 NCBI fileEvidenceTAS
GeneFCGR1AAuthorityHGNC:3613Mapping file id2209 NCBI fileEvidenceTAS
GeneFCGR2AAuthorityHGNC:3616Mapping file id2212 NCBI fileEvidenceTAS
GeneFCGR3AAuthorityHGNC:3619Mapping file id2214 NCBI fileEvidenceTAS
GeneFGRAuthorityHGNC:3697Mapping file id2268 NCBI fileEvidenceTAS
GeneFURINAuthorityHGNC:8568Mapping file id5045 NCBI fileEvidenceTAS
GeneFYNAuthorityHGNC:4037Mapping file id2534 NCBI fileEvidenceTAS
GeneFZD7AuthorityHGNC:4045Mapping file id8324 NCBI fileEvidenceIEA, TAS
GeneGGT1AuthorityHGNC:4250Mapping file id2678 NCBI fileEvidenceTAS
GeneGGT5AuthorityHGNC:4260Mapping file id2687 NCBI fileEvidenceTAS
GeneGNAI1AuthorityHGNC:4384Mapping file id2770 NCBI fileEvidenceIEA
GeneGNAI2AuthorityHGNC:4385Mapping file id2771 NCBI fileEvidenceIEA
GeneGNAI3AuthorityHGNC:4387Mapping file id2773 NCBI fileEvidenceIEA
GeneGNASAuthorityHGNC:4392Mapping file id2778 NCBI fileEvidenceIEA, TAS
GeneGNAT3AuthorityHGNC:22800Mapping file id346562 NCBI fileEvidenceIEA
GeneGNAZAuthorityHGNC:4395Mapping file id2781 NCBI fileEvidenceIEA
GeneGNB1AuthorityHGNC:4396Mapping file id2782 NCBI fileEvidenceTAS
GeneGNB2AuthorityHGNC:4398Mapping file id2783 NCBI fileEvidenceTAS
GeneGNB3AuthorityHGNC:4400Mapping file id2784 NCBI fileEvidenceTAS
GeneGNB4AuthorityHGNC:20731Mapping file id59345 NCBI fileEvidenceTAS
GeneGNB5AuthorityHGNC:4401Mapping file id10681 NCBI fileEvidenceTAS
GeneGNG10AuthorityHGNC:4402Mapping file id2790 NCBI fileEvidenceTAS
GeneGNG11AuthorityHGNC:4403Mapping file id2791 NCBI fileEvidenceTAS
GeneGNG12AuthorityHGNC:19663Mapping file id55970 NCBI fileEvidenceTAS
GeneGNG13AuthorityHGNC:14131Mapping file id51764 NCBI fileEvidenceTAS
GeneGNG2AuthorityHGNC:4404Mapping file id54331 NCBI fileEvidenceTAS
GeneGNG3AuthorityHGNC:4405Mapping file id2785 NCBI fileEvidenceTAS
GeneGNG4AuthorityHGNC:4407Mapping file id2786 NCBI fileEvidenceTAS
GeneGNG5AuthorityHGNC:4408Mapping file id2787 NCBI fileEvidenceTAS
GeneGNG7AuthorityHGNC:4410Mapping file id2788 NCBI fileEvidenceTAS
GeneGNG8AuthorityHGNC:19664Mapping file id94235 NCBI fileEvidenceTAS
GeneGNGT1AuthorityHGNC:4411Mapping file id2792 NCBI fileEvidenceTAS
GeneGNGT2AuthorityHGNC:4412Mapping file id2793 NCBI fileEvidenceTAS
GeneGRB2AuthorityHGNC:4566Mapping file id2885 NCBI fileEvidenceIEA, TAS
GeneGSDMDAuthorityHGNC:25697Mapping file id79792 NCBI fileEvidenceTAS
GeneHCKAuthorityHGNC:4840Mapping file id3055 NCBI fileEvidenceTAS
GeneHMOX1AuthorityHGNC:5013Mapping file id3162 NCBI fileEvidenceIEA
GeneHSP90AB1AuthorityHGNC:5258Mapping file id3326 NCBI fileEvidenceTAS
GeneIGHG1AuthorityHGNC:5525Mapping file idENSG00000211896 Ensembl fileEvidenceIEA, TAS
GeneIGHG2AuthorityHGNC:5526Mapping file idENSG00000211893 Ensembl fileEvidenceIEA, TAS
GeneIGHG4AuthorityHGNC:5528Mapping file idENSG00000211892 Ensembl fileEvidenceIEA, TAS
GeneIGHV1-2AuthorityHGNC:5550Mapping file idENSG00000211934 Ensembl fileEvidenceIEA, TAS
GeneIGHV1-46AuthorityHGNC:5554Mapping file idENSG00000211962 Ensembl fileEvidenceIEA, TAS
GeneIGHV1-69AuthorityHGNC:5558Mapping file idENSG00000211973 Ensembl fileEvidenceIEA, TAS

Evidence codes on this page: IEA, TAS, as the mapping file writes them; a row carrying two was written twice by the file, once under each. The mapping file id says which file placed the gene: an NCBI Gene id from NCBI2Reactome_All_Levels.txt, an Ensembl gene id from Ensembl2Reactome_All_Levels.txt. The two files can disagree about a code, so a row's codes are the one file's view. Measured by this site's build over this release on 2026-09-09: of the 138,908 human pathway-gene pairs both files place, 207 (0.149 per cent, over 47 genes) carry TAS in the Ensembl file where the NCBI rows carry IEA alone.

  • Reactome mapping files, the human rows for this pathway · Reactome release 97 · read · Reactome downloads"NCBI2Reactome_All_Levels.txt" and "Ensembl2Reactome_All_Levels.txt", Reactome, release 97, https://reactome.org/download-data/ (date of access 2026-09-09). Data CC0; attribution encouraged.

03The hierarchy

Parents and children in this release's hierarchy

Reactome's hierarchy is a graph rather than a tree: a pathway can sit under more than one parent, and the gene counts are each pathway's own placements at every level under it, so a parent's count is not the sum of its children's.

  • Reactome, the human pathway list and hierarchy relationship file · Reactome release 97 · read · Reactome downloads"ReactomePathways.txt" and "ReactomePathwaysRelation.txt", Reactome, release 97, https://reactome.org/download-data/ (date of access 2026-09-09). Data CC0; attribution encouraged.