Pathway Human Homo sapiens
Parasitic Infection Pathways
R-HSA-9824443 in Reactome release 97: under Infectious disease, with 223 genes placed in it by the mapping files and 1 child pathway in the hierarchy.
The same number in the other species
Reactome writes the mouse and rat events it infers from a human pathway under the human number with the species token. A door opens only where that species' own list in this release holds the id; neither of the other two lists holds it. Whether the event was inferred from this one is what the record says.
01The record
Reactome's own record of this pathway
What this tells you
The pathway list, the hierarchy and the genes on this page are read from the files Reactome publishes for Reactome release 97, built into this site on 2026-09-09: the pathway list, the hierarchy relationship file and the two gene mapping files. The record card is the one live read, Reactome's own record of this pathway.
Reactome's download page describes the mapping files: Mapping files link the source database identifier to the lowest level pathway diagram or subset of the pathway, all levels of the pathway hierarchy or database identifier to all reactions.
[R13] The gene list here is the all-levels mapping of NCBI Gene ids, filled from the all-levels mapping of Ensembl ids where the NCBI file has no row for a gene; each row names which file it came from by the shape of its source id. Each row carries the evidence codes the file writes for it, as written and unranked, and both where the file writes both; no page of Reactome's documentation the survey read defines the codes, so this page does not expand them. A gene id the identity files do not name is kept as the source's own id with no door rather than turned into a symbol.
On citing what a search finds, Reactome says: It should be remembered that while we strive to contain the most current and accurate data, Reactome should not be used in citations where other primary sources of information are available.
[R12] The record card prints the literature Reactome attaches to a curated pathway for that reason. The data are public domain: All data in the Reactome database and files derived from that data are licensed under the Creative Commons Public Domain Dedication (CC0). User may copy, modify, and distribute these data, even for commercial purposes, without asking for permission. Attribution is encouraged but not required.
[R10] The pathway illustrations are licensed apart, under CC BY 4.0, and none is shown here.
A gene on this list is one Reactome places in this pathway in this release, and that is all the row says: it does not say the gene is expressed in a tissue or associated with a disease, which are the other two explorers' questions, read from other sources. Reactome's papers of record are [R01] [R02].
- [R01] Ragueneau E, Gong C, Sinquin P, Sevilla C, Beavers D, Grentner A, et al. (2026). The Reactome Knowledgebase 2026. Nucleic Acids Research 54:D673-D681. PMID 41251150, doi 10.1093/nar/gkaf1223.
- [R02] Milacic M, Beavers D, Conley P, Gong C, Gillespie M, Griss J, et al. (2024). The Reactome Pathway Knowledgebase 2024. Nucleic Acids Research 52:D672-D678. PMID 37941124, doi 10.1093/nar/gkad1025.
- [R10] Reactome, reactome.org. License Agreement. https://reactome.org/license, read 2026-09-09.
- [R12] Reactome, reactome.org. Citing us. https://reactome.org/cite, read 2026-09-09.
- [R13] Reactome, reactome.org. Download. https://reactome.org/download-data, read 2026-09-09.
02The genes
Genes Reactome places in this human pathway
The mapping files place 223 genes in this human pathway; showing 1 to 100, in pages of 100, sorted by symbol for reading. The order carries no ranking.
| Gene | Authority id | Mapping file id | Evidence codes |
|---|---|---|---|
| GeneABI1 | AuthorityHGNC:11320 | Mapping file id10006 NCBI file | EvidenceIEA, TAS |
| GeneABI2 | AuthorityHGNC:24011 | Mapping file id10152 NCBI file | EvidenceIEA, TAS |
| GeneABL1 | AuthorityHGNC:76 | Mapping file id25 NCBI file | EvidenceTAS |
| GeneACTB | AuthorityHGNC:132 | Mapping file id60 NCBI file | EvidenceIEA, TAS |
| GeneACTG1 | AuthorityHGNC:144 | Mapping file id71 NCBI file | EvidenceIEA, TAS |
| GeneACTR2 | AuthorityHGNC:169 | Mapping file id10097 NCBI file | EvidenceIEA, TAS |
| GeneACTR3 | AuthorityHGNC:170 | Mapping file id10096 NCBI file | EvidenceIEA, TAS |
| GeneADAM17 | AuthorityHGNC:195 | Mapping file id6868 NCBI file | EvidenceTAS |
| GeneADCY1 | AuthorityHGNC:232 | Mapping file id107 NCBI file | EvidenceIEA, TAS |
| GeneADCY2 | AuthorityHGNC:233 | Mapping file id108 NCBI file | EvidenceIEA, TAS |
| GeneADCY3 | AuthorityHGNC:234 | Mapping file id109 NCBI file | EvidenceIEA, TAS |
| GeneADCY4 | AuthorityHGNC:235 | Mapping file id196883 NCBI file | EvidenceIEA, TAS |
| GeneADCY5 | AuthorityHGNC:236 | Mapping file id111 NCBI file | EvidenceIEA, TAS |
| GeneADCY6 | AuthorityHGNC:237 | Mapping file id112 NCBI file | EvidenceIEA, TAS |
| GeneADCY7 | AuthorityHGNC:238 | Mapping file id113 NCBI file | EvidenceIEA, TAS |
| GeneADCY8 | AuthorityHGNC:239 | Mapping file id114 NCBI file | EvidenceIEA, TAS |
| GeneADCY9 | AuthorityHGNC:240 | Mapping file id115 NCBI file | EvidenceIEA, TAS |
| GeneADORA2B | AuthorityHGNC:264 | Mapping file id136 NCBI file | EvidenceTAS |
| GeneAHCYL1 | AuthorityHGNC:344 | Mapping file id10768 NCBI file | EvidenceIEA |
| GeneAPP | AuthorityHGNC:620 | Mapping file id351 NCBI file | EvidenceTAS |
| GeneARPC1A | AuthorityHGNC:703 | Mapping file id10552 NCBI file | EvidenceIEA, TAS |
| GeneARPC1B | AuthorityHGNC:704 | Mapping file id10095 NCBI file | EvidenceIEA, TAS |
| GeneARPC2 | AuthorityHGNC:705 | Mapping file id10109 NCBI file | EvidenceIEA, TAS |
| GeneARPC3 | AuthorityHGNC:706 | Mapping file id10094 NCBI file | EvidenceIEA, TAS |
| GeneARPC4 | AuthorityHGNC:707 | Mapping file id10093 NCBI file | EvidenceIEA, TAS |
| GeneARPC5 | AuthorityHGNC:708 | Mapping file id10092 NCBI file | EvidenceIEA, TAS |
| GeneBAIAP2 | AuthorityHGNC:947 | Mapping file id10458 NCBI file | EvidenceIEA, TAS |
| GeneBRK1 | AuthorityHGNC:23057 | Mapping file id55845 NCBI file | EvidenceIEA, TAS |
| GeneBTK | AuthorityHGNC:1133 | Mapping file id695 NCBI file | EvidenceTAS |
| GeneC3 | AuthorityHGNC:1318 | Mapping file id718 NCBI file | EvidenceTAS |
| GeneC3AR1 | AuthorityHGNC:1319 | Mapping file id719 NCBI file | EvidenceTAS |
| GeneCALM1 | AuthorityHGNC:1442 | Mapping file id801 NCBI file | EvidenceIEA, TAS |
| GeneCALM2 | AuthorityHGNC:1445 | Mapping file id805 NCBI file | EvidenceIEA, TAS |
| GeneCALM3 | AuthorityHGNC:1449 | Mapping file id808 NCBI file | EvidenceIEA, TAS |
| GeneCASP1 | AuthorityHGNC:1499 | Mapping file id834 NCBI file | EvidenceTAS |
| GeneCD163 | AuthorityHGNC:1631 | Mapping file id9332 NCBI file | EvidenceTAS |
| GeneCD247 | AuthorityHGNC:1677 | Mapping file id919 NCBI file | EvidenceTAS |
| GeneCD3G | AuthorityHGNC:1675 | Mapping file id917 NCBI file | EvidenceTAS |
| GeneCDC42 | AuthorityHGNC:1736 | Mapping file id998 NCBI file | EvidenceIEA, TAS |
| GeneCREB1 | AuthorityHGNC:2345 | Mapping file id1385 NCBI file | EvidenceIEA, TAS |
| GeneCRK | AuthorityHGNC:2362 | Mapping file id1398 NCBI file | EvidenceTAS |
| GeneCTSG | AuthorityHGNC:2532 | Mapping file id1511 NCBI file | EvidenceTAS |
| GeneCYBA | AuthorityHGNC:2577 | Mapping file id1535 NCBI file | EvidenceTAS |
| GeneCYFIP1 | AuthorityHGNC:13759 | Mapping file id23191 NCBI file | EvidenceIEA, TAS |
| GeneCYFIP2 | AuthorityHGNC:13760 | Mapping file id26999 NCBI file | EvidenceIEA, TAS |
| GeneCYSLTR1 | AuthorityHGNC:17451 | Mapping file id10800 NCBI file | EvidenceTAS |
| GeneCYSLTR2 | AuthorityHGNC:18274 | Mapping file id57105 NCBI file | EvidenceTAS |
| GeneDOCK1 | AuthorityHGNC:2987 | Mapping file id1793 NCBI file | EvidenceTAS |
| GeneDPEP1 | AuthorityHGNC:3002 | Mapping file id1800 NCBI file | EvidenceTAS |
| GeneDPEP2 | AuthorityHGNC:23028 | Mapping file id64174 NCBI file | EvidenceTAS |
| GeneDVL1 | AuthorityHGNC:3084 | Mapping file id1855 NCBI file | EvidenceIEA, TAS |
| GeneDVL2 | AuthorityHGNC:3086 | Mapping file id1856 NCBI file | EvidenceIEA, TAS |
| GeneDVL3 | AuthorityHGNC:3087 | Mapping file id1857 NCBI file | EvidenceIEA, TAS |
| GeneELMO1 | AuthorityHGNC:16286 | Mapping file id9844 NCBI file | EvidenceTAS |
| GeneELMO2 | AuthorityHGNC:17233 | Mapping file id63916 NCBI file | EvidenceTAS |
| GeneENTPD1 | AuthorityHGNC:3363 | Mapping file id953 NCBI file | EvidenceTAS |
| GeneENTPD5 | AuthorityHGNC:3367 | Mapping file id957 NCBI file | EvidenceTAS |
| GeneFCGR1A | AuthorityHGNC:3613 | Mapping file id2209 NCBI file | EvidenceTAS |
| GeneFCGR2A | AuthorityHGNC:3616 | Mapping file id2212 NCBI file | EvidenceTAS |
| GeneFCGR3A | AuthorityHGNC:3619 | Mapping file id2214 NCBI file | EvidenceTAS |
| GeneFGR | AuthorityHGNC:3697 | Mapping file id2268 NCBI file | EvidenceTAS |
| GeneFURIN | AuthorityHGNC:8568 | Mapping file id5045 NCBI file | EvidenceTAS |
| GeneFYN | AuthorityHGNC:4037 | Mapping file id2534 NCBI file | EvidenceTAS |
| GeneFZD7 | AuthorityHGNC:4045 | Mapping file id8324 NCBI file | EvidenceIEA, TAS |
| GeneGGT1 | AuthorityHGNC:4250 | Mapping file id2678 NCBI file | EvidenceTAS |
| GeneGGT5 | AuthorityHGNC:4260 | Mapping file id2687 NCBI file | EvidenceTAS |
| GeneGNAI1 | AuthorityHGNC:4384 | Mapping file id2770 NCBI file | EvidenceIEA |
| GeneGNAI2 | AuthorityHGNC:4385 | Mapping file id2771 NCBI file | EvidenceIEA |
| GeneGNAI3 | AuthorityHGNC:4387 | Mapping file id2773 NCBI file | EvidenceIEA |
| GeneGNAS | AuthorityHGNC:4392 | Mapping file id2778 NCBI file | EvidenceIEA, TAS |
| GeneGNAT3 | AuthorityHGNC:22800 | Mapping file id346562 NCBI file | EvidenceIEA |
| GeneGNAZ | AuthorityHGNC:4395 | Mapping file id2781 NCBI file | EvidenceIEA |
| GeneGNB1 | AuthorityHGNC:4396 | Mapping file id2782 NCBI file | EvidenceTAS |
| GeneGNB2 | AuthorityHGNC:4398 | Mapping file id2783 NCBI file | EvidenceTAS |
| GeneGNB3 | AuthorityHGNC:4400 | Mapping file id2784 NCBI file | EvidenceTAS |
| GeneGNB4 | AuthorityHGNC:20731 | Mapping file id59345 NCBI file | EvidenceTAS |
| GeneGNB5 | AuthorityHGNC:4401 | Mapping file id10681 NCBI file | EvidenceTAS |
| GeneGNG10 | AuthorityHGNC:4402 | Mapping file id2790 NCBI file | EvidenceTAS |
| GeneGNG11 | AuthorityHGNC:4403 | Mapping file id2791 NCBI file | EvidenceTAS |
| GeneGNG12 | AuthorityHGNC:19663 | Mapping file id55970 NCBI file | EvidenceTAS |
| GeneGNG13 | AuthorityHGNC:14131 | Mapping file id51764 NCBI file | EvidenceTAS |
| GeneGNG2 | AuthorityHGNC:4404 | Mapping file id54331 NCBI file | EvidenceTAS |
| GeneGNG3 | AuthorityHGNC:4405 | Mapping file id2785 NCBI file | EvidenceTAS |
| GeneGNG4 | AuthorityHGNC:4407 | Mapping file id2786 NCBI file | EvidenceTAS |
| GeneGNG5 | AuthorityHGNC:4408 | Mapping file id2787 NCBI file | EvidenceTAS |
| GeneGNG7 | AuthorityHGNC:4410 | Mapping file id2788 NCBI file | EvidenceTAS |
| GeneGNG8 | AuthorityHGNC:19664 | Mapping file id94235 NCBI file | EvidenceTAS |
| GeneGNGT1 | AuthorityHGNC:4411 | Mapping file id2792 NCBI file | EvidenceTAS |
| GeneGNGT2 | AuthorityHGNC:4412 | Mapping file id2793 NCBI file | EvidenceTAS |
| GeneGRB2 | AuthorityHGNC:4566 | Mapping file id2885 NCBI file | EvidenceIEA, TAS |
| GeneGSDMD | AuthorityHGNC:25697 | Mapping file id79792 NCBI file | EvidenceTAS |
| GeneHCK | AuthorityHGNC:4840 | Mapping file id3055 NCBI file | EvidenceTAS |
| GeneHMOX1 | AuthorityHGNC:5013 | Mapping file id3162 NCBI file | EvidenceIEA |
| GeneHSP90AB1 | AuthorityHGNC:5258 | Mapping file id3326 NCBI file | EvidenceTAS |
| GeneIGHG1 | AuthorityHGNC:5525 | Mapping file idENSG00000211896 Ensembl file | EvidenceIEA, TAS |
| GeneIGHG2 | AuthorityHGNC:5526 | Mapping file idENSG00000211893 Ensembl file | EvidenceIEA, TAS |
| GeneIGHG4 | AuthorityHGNC:5528 | Mapping file idENSG00000211892 Ensembl file | EvidenceIEA, TAS |
| GeneIGHV1-2 | AuthorityHGNC:5550 | Mapping file idENSG00000211934 Ensembl file | EvidenceIEA, TAS |
| GeneIGHV1-46 | AuthorityHGNC:5554 | Mapping file idENSG00000211962 Ensembl file | EvidenceIEA, TAS |
| GeneIGHV1-69 | AuthorityHGNC:5558 | Mapping file idENSG00000211973 Ensembl file | EvidenceIEA, TAS |
Evidence codes on this page: IEA, TAS, as the mapping file writes them; a row carrying two was written twice by the file, once under each. The mapping file id says which file placed the gene: an NCBI Gene id from NCBI2Reactome_All_Levels.txt, an Ensembl gene id from Ensembl2Reactome_All_Levels.txt. The two files can disagree about a code, so a row's codes are the one file's view. Measured by this site's build over this release on 2026-09-09: of the 138,908 human pathway-gene pairs both files place, 207 (0.149 per cent, over 47 genes) carry TAS in the Ensembl file where the NCBI rows carry IEA alone.
- Reactome mapping files, the human rows for this pathway · Reactome release 97 · read · Reactome downloads"NCBI2Reactome_All_Levels.txt" and "Ensembl2Reactome_All_Levels.txt", Reactome, release 97, https://reactome.org/download-data/ (date of access 2026-09-09). Data CC0; attribution encouraged.
03The hierarchy
Parents and children in this release's hierarchy
Reactome's hierarchy is a graph rather than a tree: a pathway can sit under more than one parent, and the gene counts are each pathway's own placements at every level under it, so a parent's count is not the sum of its children's.
- Reactome, the human pathway list and hierarchy relationship file · Reactome release 97 · read · Reactome downloads"ReactomePathways.txt" and "ReactomePathwaysRelation.txt", Reactome, release 97, https://reactome.org/download-data/ (date of access 2026-09-09). Data CC0; attribution encouraged.