Explore by pathway Human Homo sapiens
Pathways in human
2,883 pathways in the human list of Reactome release 97, 29 of them top-level, with 145,902 gene placements from Reactome's mapping files. Search a name, or start from a top-level pathway.
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Top-level pathways
The 29 pathways of the human list with no parent
Reactome's hierarchy file gives every other pathway at least one parent; these are the roots it descends from. Each door opens the pathway's page, where its children are listed. The gene count is the number of genes the mapping files place in the pathway at every level under it.
- AutophagyR-HSA-9612973160 genes
- Cell CycleR-HSA-1640170691 genes
- Cell-Cell communicationR-HSA-1500931364 genes
- Cellular responses to stimuliR-HSA-8953897927 genes
- Chromatin organizationR-HSA-4839726380 genes
- Circadian clockR-HSA-9909396112 genes
- Developmental BiologyR-HSA-12667381,589 genes
- Digestion and absorptionR-HSA-896374328 genes
- DiseaseR-HSA-16436852,550 genes
- DNA RepairR-HSA-73894368 genes
- DNA ReplicationR-HSA-69306186 genes
- Drug ADMER-HSA-9748784109 genes
- Extracellular matrix organizationR-HSA-1474244321 genes
- Gene expression (Transcription)R-HSA-741601,545 genes
- HemostasisR-HSA-109582692 genes
- Immune SystemR-HSA-1682562,484 genes
- MetabolismR-HSA-14307282,196 genes
- Metabolism of proteinsR-HSA-3924992,148 genes
- Metabolism of RNAR-HSA-8953854751 genes
- Muscle contractionR-HSA-397014205 genes
- Neuronal SystemR-HSA-112316416 genes
- Organelle biogenesis and maintenanceR-HSA-1852241330 genes
- Programmed Cell DeathR-HSA-5357801204 genes
- Protein localizationR-HSA-9609507164 genes
- ReproductionR-HSA-1474165158 genes
- Sensory PerceptionR-HSA-9709957641 genes
- Signal TransductionR-HSA-1625822,631 genes
- Transport of small moleculesR-HSA-382551722 genes
- Vesicle-mediated transportR-HSA-5653656735 genes
- Reactome, the human pathway list and hierarchy · Reactome release 97 · read · Reactome downloads"ReactomePathways.txt" and "ReactomePathwaysRelation.txt", Reactome, release 97, https://reactome.org/download-data/ (date of access 2026-09-09). Data CC0; attribution encouraged.